Zhiyuan Hu

Zhiyuan Hu

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Plastin 3 down-regulation augments the sensitivity of MDA-MB-231 cells to paclitaxel via the p38 MAPK signalling pathway.

Artif Cells Nanomed Biotechnol 2019 Dec;47(1):685-695

a CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety , CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China , Beijing , China.

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http://dx.doi.org/10.1080/21691401.2019.1576707DOI Listing
December 2019

Emission reduction characteristics of a catalyzed continuously regenerating trap after-treatment system and its durability performance.

J Environ Sci (China) 2019 Oct 14;84:166-173. Epub 2019 May 14.

School of Chemical and Process Engineering, Faculty of Engineering, University of Leeds, Leeds LS2 9JT, UK.

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http://dx.doi.org/10.1016/j.jes.2019.05.001DOI Listing
October 2019

Experimental study on the emission characteristics of a non-road diesel engine equipped with different after-treatment devices.

Environ Sci Pollut Res Int 2019 Sep 10;26(26):26617-26627. Epub 2019 Jul 10.

School of Automotive Studies, Tongji University, Shanghai, 201804, China.

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http://dx.doi.org/10.1007/s11356-019-05839-yDOI Listing
September 2019

Device for whole genome sequencing single circulating tumor cells from whole blood.

Lab Chip 2019 Sep;19(19):3168-3178

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, China.

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http://dx.doi.org/10.1039/c9lc00473dDOI Listing
September 2019

Breakthroughs in medicine and bioimaging with up-conversion nanoparticles.

Int J Nanomedicine 2019 23;14:7759-7780. Epub 2019 Sep 23.

Laboratory of Biomolecular Research, Department of Biology and Chemistry, Paul Scherrer Institute, Villigen, PSI 5232, Switzerland.

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http://dx.doi.org/10.2147/IJN.S221433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765331PMC
September 2019

A Novel Peptide Probe for Identification of PLS3-Expressed Cancer Cells.

Anal Chem 2019 Aug 24;91(15):9640-9647. Epub 2019 Jul 24.

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience , National Center for Nanoscience and Technology of China , Beijing 100190 , China.

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http://dx.doi.org/10.1021/acs.analchem.9b01061DOI Listing
August 2019

IGFBP7 is associated to prognosis and could suppress cell survival in cholangiocarcinoma.

Artif Cells Nanomed Biotechnol 2018 10;46(sup2):817-825. Epub 2018 Jul 10.

a CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterial and Nanosafety, CAS Center for Excellence in Nanoscience , National Center for Nanoscience and Technology of China , Beijing , China.

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http://dx.doi.org/10.1080/21691401.2018.1470524DOI Listing
June 2019

Quantitative proteomic analysis to the first commercialized liposomal paclitaxel nano-platform Lipusu revealed the molecular mechanism of the enhanced anti-tumor effect.

Artif Cells Nanomed Biotechnol 2018 19;46(sup3):S147-S155. Epub 2018 Sep 19.

a CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety , CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China , Beijing , China.

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http://dx.doi.org/10.1080/21691401.2018.1489822DOI Listing
June 2019

Boosting the Theranostic Effect of Liposomal Probes toward Prominin-1 through Optimized Dual-Site Targeting.

Anal Chem 2019 Jun 5;91(11):7245-7253. Epub 2019 Apr 5.

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience , National Center for Nanoscience and Technology of China , Beijing 100190 , China.

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http://dx.doi.org/10.1021/acs.analchem.9b00622DOI Listing
June 2019

Peptosome Coadministration Improves Nanoparticle Delivery to Tumors through NRP1-Mediated Co-Endocytosis.

Biomolecules 2019 05 5;9(5). Epub 2019 May 5.

CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China.

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http://dx.doi.org/10.3390/biom9050172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572427PMC
May 2019

Detection of Parkinson's Disease through the Peptoid Recognizing α-Synuclein in Serum.

ACS Chem Neurosci 2019 03 29;10(3):1204-1208. Epub 2019 Jan 29.

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience , National Center for Nanoscience and Technology , Beijing 100190 , China.

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http://dx.doi.org/10.1021/acschemneuro.8b00540DOI Listing
March 2019

Microenvironment-Induced In Situ Self-Assembly of Polymer-Peptide Conjugates That Attack Solid Tumors Deeply.

Angew Chem Int Ed Engl 2019 Mar 27;58(14):4632-4637. Epub 2019 Feb 27.

CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), No. 11 Beiyitiao, Zhongguancun, Beijing, 100190, China.

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http://dx.doi.org/10.1002/anie.201900135DOI Listing
March 2019

Proteomic profiling of RAW264.7 macrophage cells exposed to graphene oxide: insights into acute cellular responses.

Nanotoxicology 2019 Feb 17;13(1):35-49. Epub 2019 Jan 17.

a CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety , CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology , Beijing , China.

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https://www.tandfonline.com/doi/full/10.1080/17435390.2018.1
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http://dx.doi.org/10.1080/17435390.2018.1530389DOI Listing
February 2019

MMP-2-Controlled Transforming Micelles for Heterogeneic Targeting and Programmable Cancer Therapy.

Theranostics 2019 28;9(6):1728-1740. Epub 2019 Feb 28.

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, China.

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http://dx.doi.org/10.7150/thno.30915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485184PMC
February 2019

Association between Physical Exercise and Biomarkers of Oxidative Stress among Middle-Aged and Elderly Community Residents with Essential Hypertension in China.

Biomed Res Int 2018 3;2018:4135104. Epub 2018 Jul 3.

Department of Epidemiology and Statistics, Bengbu Medical College, 2600 Dong Hai Avenue, Bengbu 233030, China.

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https://www.hindawi.com/journals/bmri/2018/4135104/
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http://dx.doi.org/10.1155/2018/4135104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051290PMC
January 2019

Tumor-microenvironment controlled nanomicelles with AIE property for boosting cancer therapy and apoptosis monitoring.

Biomaterials 2019 01 9;188:96-106. Epub 2018 Oct 9.

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2018.10.003DOI Listing
January 2019

Targeting Peptide-Based Probes for Molecular Imaging and Diagnosis.

Adv Mater 2018 Dec 7:e1804827. Epub 2018 Dec 7.

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, P. R. China.

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http://dx.doi.org/10.1002/adma.201804827DOI Listing
December 2018

An assessment of prognostic immunity markers in breast cancer.

NPJ Breast Cancer 2018 29;4:35. Epub 2018 Oct 29.

5Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC USA.

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http://www.nature.com/articles/s41523-018-0088-0
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http://dx.doi.org/10.1038/s41523-018-0088-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206135PMC
October 2018

Quantitative Proteomic Analysis of Cell Responses to Electroporation, a Classical Gene Delivery Approach.

Proteomics 2018 08 6;18(16):e1800127. Epub 2018 Aug 6.

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, 100190, Beijing, P. R. China.

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http://dx.doi.org/10.1002/pmic.201800127DOI Listing
August 2018

Synthesis of imidazo[1,5-a]pyridines via I-mediated sp C-H amination.

Org Biomol Chem 2018 08;16(31):5653-5660

College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan Province 450001, China.

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http://dx.doi.org/10.1039/c8ob01501eDOI Listing
August 2018

Precisely Enumerating Circulating Tumor Cells Utilizing a Multi-Functional Microfluidic Chip and Unique Image Interpretation Algorithm.

Theranostics 2017 17;7(19):4710-4721. Epub 2017 Oct 17.

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, China.

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http://dx.doi.org/10.7150/thno.20440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706094PMC
July 2018

Combined peripheral natural killer cell and circulating tumor cell enumeration enhance prognostic efficiency in patients with metastatic triple-negative breast cancer.

Chin J Cancer Res 2018 Jun;30(3):315-326

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Breast Oncology, Peking University Cancer Hospital & Institute, Beijing 100142, China.

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http://dx.doi.org/10.21147/j.issn.1000-9604.2018.03.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037585PMC
June 2018

pH-Triggered Peptide Self-Assembly for Targeting Imaging and Therapy toward Angiogenesis with Enhanced Signals.

ACS Appl Mater Interfaces 2018 Mar 23;10(9):7871-7881. Epub 2018 Feb 23.

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience , National Center for Nanoscience and Technology of China , Beijing 100190 , P. R. China.

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http://dx.doi.org/10.1021/acsami.8b00583DOI Listing
March 2018

Racial Differences in PAM50 Subtypes in the Carolina Breast Cancer Study.

J Natl Cancer Inst 2018 02;110(2)

Department of Epidemiology, Lineberger Comprehensive Cancer Center; Department of Pathology and Lab Medicine, Department of Nutrition (EHA), and Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC; Dana Farber Cancer Institute, Harvard University, Boston, MA; Center for Clinical Cancer Genetics, Global Health Department of Medicine, The University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1093/jnci/djx135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059138PMC
February 2018

Device To Study the Cell Invasion Behavior and Phenotypic Profile at Single Cell Level.

Anal Chem 2018 02 22;90(3):1691-1700. Epub 2018 Jan 22.

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China , Beijing 100190, China.

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http://dx.doi.org/10.1021/acs.analchem.7b03294DOI Listing
February 2018

Multiple single cell screening and DNA MDA amplification chip for oncogenic mutation profiling.

Lab Chip 2018 02;18(5):723-734

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, China.

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http://dx.doi.org/10.1039/c7lc00924kDOI Listing
February 2018

Identifying EGFR-Expressed Cells and Detecting EGFR Multi-Mutations at Single-Cell Level by Microfluidic Chip.

Nanomicro Lett 2018 14;10(1):16. Epub 2017 Nov 14.

1CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190 People's Republic of China.

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http://link.springer.com/10.1007/s40820-017-0168-y
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http://dx.doi.org/10.1007/s40820-017-0168-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199061PMC
November 2017

HER2 Targeting Peptides Screening and Applications in Tumor Imaging and Drug Delivery.

Theranostics 2016 28;6(8):1261-73. Epub 2016 May 28.

1. CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China;; 2. CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China;

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http://www.thno.org/v06p1261.pdf
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http://dx.doi.org/10.7150/thno.14302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893650PMC
October 2017

Reconfigurable Peptide Nanotherapeutics at Tumor Microenvironmental pH.

ACS Appl Mater Interfaces 2017 Sep 31;9(36):30426-30436. Epub 2017 Aug 31.

CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST) , Beijing 100190, China.

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http://dx.doi.org/10.1021/acsami.7b09033DOI Listing
September 2017

The Functions of Circulating Tumor Cells in Early Diagnosis and Surveillance During Cancer Advancement.

J Transl Int Med 2017 Sep 30;5(3):135-138. Epub 2017 Sep 30.

Center for Neuroscience Research, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian Province, China.

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http://dx.doi.org/10.1515/jtim-2017-0029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655459PMC
September 2017

Antibody-Mimetic Peptoid Nanosheet for Label-Free Serum-Based Diagnosis of Alzheimer's Disease.

Adv Mater 2017 Aug 12;29(30). Epub 2017 Jun 12.

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory of Biological Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, 100190, China.

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http://dx.doi.org/10.1002/adma.201700057DOI Listing
August 2017

A pan-cancer genome-wide analysis reveals tumour dependencies by induction of nonsense-mediated decay.

Nat Commun 2017 06 26;8:15943. Epub 2017 Jun 26.

Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.1038/ncomms15943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490262PMC
June 2017

SPECT/CT Imaging of the Novel HER2-Targeted Peptide Probe Tc-HYNIC-H6F in Breast Cancer Mouse Models.

J Nucl Med 2017 05 19;58(5):821-826. Epub 2017 Jan 19.

Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, China

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http://dx.doi.org/10.2967/jnumed.116.183863DOI Listing
May 2017

Nanoparticle abraxane possesses impaired proliferation in A549 cells due to the underexpression of glucosamine 6-phosphate N-acetyltransferase 1 (GNPNAT1/GNA1).

Int J Nanomedicine 2017 1;12:1685-1697. Epub 2017 Mar 1.

Chinese Academy of Sciences Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, People's Republic of China.

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http://dx.doi.org/10.2147/IJN.S129976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338994PMC
May 2017

Interaction of gold and silver nanoparticles with human plasma: Analysis of protein corona reveals specific binding patterns.

Colloids Surf B Biointerfaces 2017 Apr 20;152:317-325. Epub 2017 Jan 20.

Key Laboratory for Biological Effects of Nanomaterials and Nanosafety of Chinese Academy of Sciences, Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, 100190, P.R. China; University of Chinese Academy of Sciences, Beijing, 100049, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.colsurfb.2017.01.037DOI Listing
April 2017

Peptide probes derived from pertuzumab by molecular dynamics modeling for HER2 positive tumor imaging.

PLoS Comput Biol 2017 Apr 13;13(4):e1005441. Epub 2017 Apr 13.

CAS Key Laboratory for Biological Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology, Beijing, China.

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https://dx.plos.org/10.1371/journal.pcbi.1005441
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http://dx.doi.org/10.1371/journal.pcbi.1005441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390981PMC
April 2017

I-Mediated Intramolecular C-H Amidation for the Synthesis of N-Substituted Benzimidazoles.

J Org Chem 2017 03 2;82(6):3152-3158. Epub 2017 Mar 2.

College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou, Henan Province 450001, People's Republic of China.

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http://pubs.acs.org/doi/10.1021/acs.joc.7b00142
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http://dx.doi.org/10.1021/acs.joc.7b00142DOI Listing
March 2017

Targeting peptide functionalized liposomes towards aminopeptidase N for precise tumor diagnosis and therapy.

Biomater Sci 2017 Feb;5(3):417-421

CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, P. R. China.

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http://dx.doi.org/10.1039/c6bm00898dDOI Listing
February 2017

Antiamyloidogenic Activity of Aβ42-Binding Peptoid in Modulating Amyloid Oligomerization.

Small 2017 Jan 7;13(1). Epub 2016 Oct 7.

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory of Biological Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, 100190, China.

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http://dx.doi.org/10.1002/smll.201602857DOI Listing
January 2017

Tumor detection using magnetosome nanoparticles functionalized with a newly screened EGFR/HER2 targeting peptide.

Biomaterials 2017 01 16;115:53-64. Epub 2016 Nov 16.

CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China; CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.11.022DOI Listing
January 2017

Synthesis of Quinazolines from N,N'-Disubstituted Amidines via I/KI-Mediated Oxidative C-C Bond Formation.

J Org Chem 2016 10 3;81(20):9924-9930. Epub 2016 Oct 3.

College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou, Henan Province 450001, China.

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http://dx.doi.org/10.1021/acs.joc.6b02100DOI Listing
October 2016

Identification of Human Papillomavirus Infection in Cancer Tissue by Targeted Next-generation Sequencing.

Appl Immunohistochem Mol Morphol 2016 08;24(7):490-5

*Department of Pathology and Laboratory Medicine †Lineberger Comprehensive Cancer Center ‡Department of Medicine, Division of Medical Oncology, The University of North Carolina, Chapel Hill, NC.

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http://dx.doi.org/10.1097/PAI.0000000000000215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791202PMC
August 2016

High-Throughput Peptide Screening on a Bimodal Imprinting Chip Through MS-SPRi Integration.

Methods Mol Biol 2016 ;1352:111-25

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, No.11. Beiyitiao Zhongguancun, Beijing, 100190, China.

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http://link.springer.com/10.1007/978-1-4939-3037-1_9
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http://dx.doi.org/10.1007/978-1-4939-3037-1_9DOI Listing
August 2016

Synthesis of 1,2,4-Triazolo[4,3-a]pyridines and Related Heterocycles by Sequential Condensation and Iodine-Mediated Oxidative Cyclization.

Chemistry 2016 Jul 29;22(31):11022-7. Epub 2016 Jun 29.

College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450001, P.R. China.

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http://doi.wiley.com/10.1002/chem.201601744
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http://dx.doi.org/10.1002/chem.201601744DOI Listing
July 2016

Switchable Liposomes: Targeting-Peptide-Functionalized and pH-Triggered Cytoplasmic Delivery.

ACS Appl Mater Interfaces 2016 Jul 12;8(29):18658-63. Epub 2016 Jul 12.

CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology , Beijing 100190, China.

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http://dx.doi.org/10.1021/acsami.6b05678DOI Listing
July 2016

Self-Assembled ROS-Sensitive Polymer-Peptide Therapeutics Incorporating Built-in Reporters for Evaluation of Treatment Efficacy.

Biomacromolecules 2016 05 8;17(5):1643-52. Epub 2016 Apr 8.

CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST) , Beijing, 100190, China.

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http://dx.doi.org/10.1021/acs.biomac.6b00041DOI Listing
May 2016

Abraxane, the Nanoparticle Formulation of Paclitaxel Can Induce Drug Resistance by Up-Regulation of P-gp.

PLoS One 2015 16;10(7):e0131429. Epub 2015 Jul 16.

CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing, 100190, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131429PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504487PMC
April 2016

Structure-based Design of Peptides with High Affinity and Specificity to HER2 Positive Tumors.

Theranostics 2015 1;5(10):1154-65. Epub 2015 Aug 1.

CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China.

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http://dx.doi.org/10.7150/thno.12398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533098PMC
April 2016

Switchable probes: pH-triggered and VEGFR2 targeted peptides screening through imprinting microarray.

Chem Commun (Camb) 2016 Apr;52(33):5690-3

CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China.

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http://dx.doi.org/10.1039/c6cc01302cDOI Listing
April 2016

Micromixer Based Preparation of Functionalized Liposomes and Targeting Drug Delivery.

ACS Med Chem Lett 2016 Apr 10;7(4):429-34. Epub 2016 Feb 10.

CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology of China , Beijing 100190, China.

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http://dx.doi.org/10.1021/acsmedchemlett.6b00028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834645PMC
April 2016

Performance of Three-Biomarker Immunohistochemistry for Intrinsic Breast Cancer Subtyping in the AMBER Consortium.

Cancer Epidemiol Biomarkers Prev 2016 Mar 28;25(3):470-8. Epub 2015 Dec 28.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-0874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779705PMC
March 2016

Response of Human Osteoblast to n-HA/PEEK--Quantitative Proteomic Study of Bio-effects of Nano-Hydroxyapatite Composite.

Sci Rep 2016 Mar 9;6:22832. Epub 2016 Mar 9.

Center for Craniofacial Stem Cell Research and Regeneration, Department of Orthodontics, Laboratory of Interdisciplinary Studies, Peking University School and Hospital of Stomatology, Beijing 100081, China.

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http://dx.doi.org/10.1038/srep22832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783780PMC
March 2016

Effect of ammonia stress on nitrogen metabolism of Ceratophyllum demersum.

Environ Toxicol Chem 2016 Jan 3;35(1):205-11. Epub 2015 Dec 3.

School of Resource and Environmental Science, Wuhan University, Wuhan, China.

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http://doi.wiley.com/10.1002/etc.3182
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http://dx.doi.org/10.1002/etc.3182DOI Listing
January 2016

Pathological-Condition-Driven Construction of Supramolecular Nanoassemblies for Bacterial Infection Detection.

Adv Mater 2016 Jan 16;28(2):254-62. Epub 2015 Nov 16.

Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), No. 11 Beiyitiao, Zhongguancun, Beijing, 100190, China.

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http://doi.wiley.com/10.1002/adma.201503437
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January 2016

Distinguishing of tumor cell-targeting peptide ligands through a color-encoding microarray.

Lab Chip 2015 Dec 4;15(24):4512-6. Epub 2015 Nov 4.

CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology of China, Beijing 100190, China.

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http://dx.doi.org/10.1039/c5lc01010aDOI Listing
December 2015

Discovering of Tumor-targeting Peptides using Bi-functional Microarray.

Adv Healthc Mater 2015 Dec 9;4(18):2802-8. Epub 2015 Nov 9.

CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology of China, Beijing, 100190, China.

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http://doi.wiley.com/10.1002/adhm.201500724
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December 2015

Energy Migration Engineering of Bright Rare-Earth Upconversion Nanoparticles for Excitation by Light-Emitting Diodes.

Adv Mater 2015 Nov 22;27(41):6418-22. Epub 2015 Sep 22.

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, Beijing, 100190, China.

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November 2015

Quantitative Proteomic Analysis of Cellular Resistance to the Nanoparticle Abraxane.

ACS Nano 2015 Oct 9;9(10):10099-112. Epub 2015 Sep 9.

CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology of China, Chinese Academy of Sciences , Beijing 100190, China.

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http://dx.doi.org/10.1021/acsnano.5b03677DOI Listing
October 2015

Fast assembling microarrays of superparamagnetic Fe3O4@Au nanoparticle clusters as reproducible substrates for surface-enhanced Raman scattering.

Nanoscale 2015 Aug 16;7(32):13427-37. Epub 2015 Jun 16.

Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-based Functional Materials & Devices, Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu Province 215123, China.

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http://xlink.rsc.org/?DOI=C5NR02491A
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August 2015

Microarray based screening of peptide nano probes for HER2 positive tumor.

Anal Chem 2015 Aug 6;87(16):8367-72. Epub 2015 Aug 6.

§Institute for Systems Biology, 401 Terry Avenue North, Seattle, Washington 98109, United States.

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http://dx.doi.org/10.1021/acs.analchem.5b01588DOI Listing
August 2015

Ammonia stress on the carbon metabolism of Ceratophyllum demersum.

Environ Toxicol Chem 2015 Apr 27;34(4):843-9. Epub 2015 Feb 27.

Research Institute of Environmental Sciences, College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, China; School of Resource and Environmental Science, Wuhan University, Wuhan, China.

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http://dx.doi.org/10.1002/etc.2866DOI Listing
April 2015

A fluorescent Arg-Gly-Asp (RGD) peptide-naphthalenediimide (NDI) conjugate for imaging integrin α(v)β(3) in vitro.

Chem Commun (Camb) 2015 Apr 3;51(32):6901-4. Epub 2015 Feb 3.

State Key Lab of Heavy Oil Processing, China University of Petroleum-Beijing, No. 18 Fuxue Road, 102249, Beijing, China.

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http://dx.doi.org/10.1039/c4cc08265fDOI Listing
April 2015

Label-free detection microarray for novel peptide ligands screening base on MS-SPRi combination.

Talanta 2015 Mar 18;134:705-711. Epub 2014 Dec 18.

CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology of China, Beijing 100190, China; Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing 102206, China; Institute for Systems Biology, 401 Terry Avenue N, Seattle, WA 98109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.talanta.2014.12.012DOI Listing
March 2015

Label-free detection of Alzheimer's disease through the ADP3 peptoid recognizing the serum amyloid-beta42 peptide.

Chem Commun (Camb) 2015 Jan;51(4):718-21

National Center for Nanoscience and Technology, No. 11, Beiyitiao Zhongguancun, Beijing, 100190, P.R. China.

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http://dx.doi.org/10.1039/c4cc07037bDOI Listing
January 2015

Rapid screening of peptide probes through in situ single-bead sequencing microarray.

Anal Chem 2014 Dec 14;86(23):11854-9. Epub 2014 Nov 14.

CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology of China , Beijing 100190, China.

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http://dx.doi.org/10.1021/ac503454zDOI Listing
December 2014

Betaine homocysteine methyltransferase (BHMT) as a specific and sensitive blood marker for acute liver injury.

Biomarkers 2014 Nov 21;19(7):578-84. Epub 2014 Aug 21.

National Center for Nanoscience and Technology , Beijing , P.R. China .

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http://dx.doi.org/10.3109/1354750X.2014.951880DOI Listing
November 2014

A flexible microneedle array as low-voltage electroporation electrodes for in vivo DNA and siRNA delivery.

Lab Chip 2014 Oct;14(20):4093-102

National Center for Nanoscience and Technology, Beijing 100190, China.

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October 2014

Flow-through cell electroporation microchip integrating dielectrophoretic viable cell sorting.

Anal Chem 2014 Oct 6;86(20):10215-22. Epub 2014 Oct 6.

National Center for Nanoscience and Technology , Beijing 100190, China.

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http://dx.doi.org/10.1021/ac502294eDOI Listing
October 2014

Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity.

Theranostics 2014 14;4(2):215-28. Epub 2014 Jan 14.

2. Institute for Systems Biology, 401 Terry Avenue N, Seattle, Washington 98109, USA.

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http://www.thno.org/v04p0215.htm
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900804PMC
September 2014

Label-free quantitative detection of tumor-derived exosomes through surface plasmon resonance imaging.

Anal Chem 2014 Sep 11;86(17):8857-64. Epub 2014 Aug 11.

National Center for Nanoscience and Technology , No. 11, Beiyitiao Zhongguancun, Beijing 100190, P. R. China.

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http://pubs.acs.org/doi/10.1021/ac5023056
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151789PMC
September 2014

LSECtin expressed on melanoma cells promotes tumor progression by inhibiting antitumor T-cell responses.

Cancer Res 2014 Jul 25;74(13):3418-28. Epub 2014 Apr 25.

Authors' Affiliations: State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine; College of Life Sciences, Peking University; and Department of Biology Sciences and Biotechnology, Tsinghua University, Beijing, China

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2690DOI Listing
July 2014

Bimodal imprint chips for peptide screening: integration of high-throughput sequencing by MS and affinity analyses by surface plasmon resonance imaging.

Anal Chem 2014 Apr 24;86(8):3703-7. Epub 2014 Mar 24.

CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology of China , Beijing 100190, China.

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http://dx.doi.org/10.1021/ac500465eDOI Listing
April 2014

An automated Teflon microfluidic peptide synthesizer.

Lab Chip 2013 Sep 8;13(17):3347-50. Epub 2013 Jul 8.

National Center for Nanoscience and Technology, No.11 ZhongGuanCun BeiYiTiao, 100190 Beijing, PR China.

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http://dx.doi.org/10.1039/c3lc50632kDOI Listing
September 2013

Ultrafine particle emission characteristics of diesel engine by on-board and test bench measurement.

J Environ Sci (China) 2012 ;24(11):1972-8

School of Automobile Studies, Tongji University, Shanghai 201804, China.

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http://dx.doi.org/10.1016/s1001-0742(11)61038-3DOI Listing
May 2013

Circulating tumor cells in HER2-positive metastatic breast cancer patients: a valuable prognostic and predictive biomarker.

BMC Cancer 2013 Apr 23;13:202. Epub 2013 Apr 23.

Department of Breast Cancer, Affiliated Hospital of Academy of Military Medical Sciences, No.8 Dongdajie, Beijing, 100071, China.

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http://dx.doi.org/10.1186/1471-2407-13-202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643882PMC
April 2013

Clinical implementation of RNA signatures for pharmacogenomic decision-making.

Pharmgenomics Pers Med 2011 8;4:95-107. Epub 2011 Sep 8.

Department of Pathology and Laboratory Medicine.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513222PMC
December 2012

Circulating microRNA-122 as a potential biomarker for liver injury.

Mol Med Rep 2012 Jun 15;5(6):1428-32. Epub 2012 Mar 15.

School of Life Science, Zhejiang Sci-Tech University, Hangzhou, Zhejiang , People's Republic of China.

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http://dx.doi.org/10.3892/mmr.2012.838DOI Listing
June 2012

Quality assurance of RNA expression profiling in clinical laboratories.

J Mol Diagn 2012 Jan 20;14(1):1-11. Epub 2011 Oct 20.

Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, 27599-7525, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338342PMC
January 2012

Label-free detection with surface plasmon resonance imaging.

Methods Mol Biol 2011 ;723:321-33

Institute for Systems Biology, Seattle, WA, USA.

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http://link.springer.com/10.1007/978-1-61779-043-0_20
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June 2011

Systematic bias in genomic classification due to contaminating non-neoplastic tissue in breast tumor samples.

BMC Med Genomics 2011 Jun 30;4:54. Epub 2011 Jun 30.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151208PMC
June 2011

Towards nanomedicines: design protocols to assemble, visualize and test carbon nanotube probes for multi-modality biomedical imaging.

Philos Trans A Math Phys Eng Sci 2010 Aug;368(1924):3683-712

Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK.

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http://dx.doi.org/10.1098/rsta.2010.0081DOI Listing
August 2010

SPR imaging for high throughput, label-free interaction analysis.

Comb Chem High Throughput Screen 2009 Sep 1;12(8):741-51. Epub 2009 Sep 1.

Institute for Systems Biology, Seattle, Washington 98103, USA.

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http://dx.doi.org/10.2174/138620709789104933DOI Listing
September 2009

Circulating microRNAs, potential biomarkers for drug-induced liver injury.

Proc Natl Acad Sci U S A 2009 Mar 25;106(11):4402-7. Epub 2009 Feb 25.

Institute for Systems Biology, 1441 North 34th Street, Seattle, WA 98103, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657429PMC
March 2009