Publications by authors named "Zhiqing Lv"

3 Publications

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Eye pain and blurred vision as main complaints in a new case with MDPL syndrome.

Eur J Ophthalmol 2021 Apr 16:11206721211009179. Epub 2021 Apr 16.

Department of ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Introduction: We report a novel phenotype of mandibular hypoplasia, deafness, and progeroid features with lipodystrophy (MDPL) syndrome with mutation in a Chinese girl.

Case Description: Diabetic retinopathy was detected as the primary manifestation in a Chinese girl with MDPL syndrome carrying a known mutation (c.1812_1814delCTC, p.Ser605del). Typical characteristics of the syndrome including mandibular hypoplasia, deafness, progeroid features, and diabetes were detected after comprehensive examinations. The patient suffered from blurred vision and eye pain due to the neovascularization of the retina (vitreous hemorrhage and retinal detachment) and iris (neovascular glaucoma). The literature review revealed that the prevalence of hepatomegaly and abnormal triglyceride levels were significantly higher in female than in male with MDPL syndrome carrying mutations.

Conclusion: These results expand our knowledge regarding the clinical phenotypes of MDPL syndrome with mutations. Diabetic retinopathy is a non-negligible complication of MDPL syndrome. The phenotype varies among female and male patients with the syndrome. Hepatomegaly and abnormal triglyceride levels are more common in female patients with MDPL syndrome.
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http://dx.doi.org/10.1177/11206721211009179DOI Listing
April 2021

Preparation and Mechanical Behavior of Ultra-High Strength Low-Carbon Steel.

Materials (Basel) 2020 Jan 18;13(2). Epub 2020 Jan 18.

Key Laboratory of Advanced Forging & Stamping Technology and Science, Ministry of Education of China Yanshan University, Qinhuangdao 066004, China.

The low-carbon steel (~0.12 wt%) with complete martensite structure, obtained by quenching, was cold rolled to get the high-strength steel sheets. Then, the mechanical properties of the sheets were measured at different angles to the rolling direction, and the microstructural evolution of low-carbon martensite with cold rolling reduction was observed. The results show that the hardness and the strength gradually increase with increasing rolling reduction, while the elongation and impact toughness obviously decrease. The strength of the sheets with the same rolling reduction are different at the angles of 0°, 45°, and 90° to the rolling direction. The tensile strength (elongation) along the rolling direction is higher than that in the other two directions, but the differences between them are not obvious. When the aging was performed at a low temperature, the strength of the initial martensite and deformed martensite increased with increasing aging time during the early stages of aging, followed by a gradual decrease with further aging. However, the elongation increases with increasing aging time. The change of hardness is consistent with that of strength for the cold-rolled martensite, while the hardness of the initial martensite decreases gradually with increasing aging time.
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http://dx.doi.org/10.3390/ma13020459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013394PMC
January 2020

Structural Properties and Phase Stability of Primary Y Phase (Ti₂SC) in Ti-Stabilized Stainless Steel from Experiments and First Principles.

Materials (Basel) 2019 Apr 4;12(7). Epub 2019 Apr 4.

Key Laboratory of Advanced Forging & Stamping Technology and Science (Yanshan University), Ministry of Education of China, Qinhuangdao 066004, China.

The morphology and microstructural evaluation of Y phases in AISI 321 (a Ti-stabilized stainless steel) were characterized after hot deformation. The electronic structure and phase stability of titanium carbosulfide were further discussed by first-principle calculations. It was found that Y phases, like curved strips or bones in AISI 321 stainless steel, mostly show a clustered distribution and are approximately arranged in parallel. The width of the Y phase is much less than the length, and the composition of the Y phase is close to that of Ti₂SC. Y phases have exceptional thermal stability. The morphology of Y phases changed considerably after forging. During the first calculations, the Ti₂SC with hexagonal structure does not spontaneously change into TiS and TiC; however Ti₄S₂C₂ (Z = 2) can spontaneously change into the two phases. The Ti-S bonds are compressed in Ti₄S₂C₂ cells, which leads to poor structural stability for Ti₄S₂C₂. There is a covalent interaction between C/S and Ti, as well as an exchange of electrons between Ti and S/C atoms. Evidently, the mechanical stability of Ti₄S₂C₂ is weak; however, Ti₂SC shows high stability. Ti₂SC, as a hard brittle phase, does not easily undergo plastic deformation.
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http://dx.doi.org/10.3390/ma12071118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480572PMC
April 2019