Zhili Zheng

Zhili Zheng

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Zhili Zheng

Zhili Zheng

Publications by authors named "Zhili Zheng"

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A resource-efficient tool for mixed model association analysis of large-scale data.

Nat Genet 2019 Dec 25;51(12):1749-1755. Epub 2019 Nov 25.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/s41588-019-0530-8DOI Listing
December 2019

Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy.

Cancer Immunol Res 2019 Nov 4;7(11):1824-1836. Epub 2019 Sep 4.

Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1158/2326-6066.CIR-19-0299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825592PMC
November 2019

Identification of Neoantigen-Reactive Tumor-Infiltrating Lymphocytes in Primary Bladder Cancer.

J Immunol 2019 Jun 29;202(12):3458-3467. Epub 2019 Apr 29.

Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;

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http://dx.doi.org/10.4049/jimmunol.1801022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548619PMC
June 2019

Genome-wide association study of medication-use and associated disease in the UK Biobank.

Nat Commun 2019 04 23;10(1):1891. Epub 2019 Apr 23.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-019-09572-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478889PMC
April 2019

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

Nat Genet 2018 07 23;50(8):1112-1121. Epub 2018 Jul 23.

National Bureau of Economic Research, Cambridge, MA, USA.

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http://www.nature.com/articles/s41588-018-0147-3
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http://dx.doi.org/10.1038/s41588-018-0147-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393768PMC
July 2018

Global genetic differentiation of complex traits shaped by natural selection in humans.

Nat Commun 2018 05 14;9(1):1865. Epub 2018 May 14.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-018-04191-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951811PMC
May 2018

An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors.

Mol Ther 2018 02 28;26(2):379-389. Epub 2017 Oct 28.

Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2017.10.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835023PMC
February 2018

Causal associations between risk factors and common diseases inferred from GWAS summary data.

Nat Commun 2018 01 15;9(1):224. Epub 2018 Jan 15.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-017-02317-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768719PMC
January 2018

Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II-Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3.

J Clin Oncol 2017 Oct 15;35(29):3322-3329. Epub 2017 Aug 15.

Yong-Chen Lu, Linda L. Parker, Tangying Lu, Zhili Zheng, Mary Ann Toomey, Donald E. White, Xin Yao, Yong F. Li, Paul F. Robbins, Steven A. Feldman, Christopher A. Klebanoff, Stephanie L. Goff, Richard M. Sherry, Udai S. Kammula, James C. Yang, and Steven A. Rosenberg, National Cancer Institute, Bethesda, MD; Pierre van der Bruggen, Ludwig Institute for Cancer Research; De Duve Institute, Université Catholique de Louvain, Brussels; and Walloon Excellence in Life Sciences and Biotechnology (WELBIO), Wallonia, Belgium; Christopher A. Klebanoff, Memorial Sloan Kettering Cancer Center, Parker Institute for Cancer Immunotherapy, New York, NY.

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http://dx.doi.org/10.1200/JCO.2017.74.5463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652397PMC
October 2017

Quantifying the mapping precision of genome-wide association studies using whole-genome sequencing data.

Genome Biol 2017 05 16;18(1):86. Epub 2017 May 16.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://genomebiology.biomedcentral.com/articles/10.1186/s130
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http://dx.doi.org/10.1186/s13059-017-1216-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432979PMC
May 2017

Genetic signatures of high-altitude adaptation in Tibetans.

Proc Natl Acad Sci U S A 2017 04 3;114(16):4189-4194. Epub 2017 Apr 3.

The Eye Hospital, School of Ophthalmology & Optometry, Wenzhou Medical University, China National Engineering Research Center of Ophthalmology and Optometry, State Key Laboratory Cultivation Base and Key Laboratory of Vision Science, Ministry of Health, Wenzhou 325027, China

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http://dx.doi.org/10.1073/pnas.1617042114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402460PMC
April 2017

Comparison of three monocular methods for measuring accommodative stimulus-response curves.

Clin Exp Optom 2017 Mar 3;100(2):155-161. Epub 2016 Nov 3.

School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.

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http://dx.doi.org/10.1111/cxo.12469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347892PMC
March 2017

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer.

N Engl J Med 2016 Dec;375(23):2255-2262

From the Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1056/NEJMoa1609279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178827PMC
December 2016

The up-regulation of long non-coding RNA CCAT2 indicates a poor prognosis for prostate cancer and promotes metastasis by affecting epithelial-mesenchymal transition.

Biochem Biophys Res Commun 2016 Nov 21;480(4):508-514. Epub 2016 Aug 21.

Department of Urology Surgery, Renmin Hospital, Hanzhong, Shaanxi Province, 723000, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.08.120DOI Listing
November 2016

Immunogenicity of somatic mutations in human gastrointestinal cancers.

Science 2015 Dec 29;350(6266):1387-90. Epub 2015 Oct 29.

Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1126/science.aad1253DOI Listing
December 2015

The effects of spatial frequency on the accommodation responses of myopes and emmetropes under various detection demands.

Vision Res 2015 Oct 22;115(Pt A):1-7. Epub 2015 Aug 22.

Wenzhou Medical University [WMU], 270 Xueyuan Xi Road, 325027 Wenzhou, China; WMU-Essilor International Research Centre [WEIRC], 270 Xueyuan Xi Road, 325027 Wenzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.visres.2015.05.020DOI Listing
October 2015

Novel CD4-Based Bispecific Chimeric Antigen Receptor Designed for Enhanced Anti-HIV Potency and Absence of HIV Entry Receptor Activity.

J Virol 2015 Jul 15;89(13):6685-94. Epub 2015 Apr 15.

Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

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http://dx.doi.org/10.1128/JVI.00474-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468509PMC
July 2015

Gamma-retroviral vector design for the co-expression of artificial microRNAs and therapeutic proteins.

Nucleic Acid Ther 2014 Oct 14;24(5):356-63. Epub 2014 Jul 14.

Surgery Branch, Center for Cancer Research, National Cancer Institute , Bethesda, Maryland.

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http://dx.doi.org/10.1089/nat.2014.0486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162432PMC
October 2014

Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells.

J Immunother Cancer 2014 19;2:25. Epub 2014 Aug 19.

Surgery Branch, Center for Cancer Research, National Cancer Institute, 10 Center Drive, Building 10 Hatfield CRC, Rm 3-5930, 20892-1201 Bethesda, MD, USA ; Current address: Bluebird bio, 150 Second St, Cambridge, MA 02141, USA.

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http://dx.doi.org/10.1186/2051-1426-2-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155770PMC
September 2014

Gene expression profiling using nanostring digital RNA counting to identify potential target antigens for melanoma immunotherapy.

Clin Cancer Res 2013 Sep 10;19(18):4941-50. Epub 2013 Sep 10.

Authors' Affiliation: Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778100PMC
September 2013

Evaluation of γ-retroviral vectors that mediate the inducible expression of IL-12 for clinical application.

J Immunother 2012 Jun;35(5):430-9

Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1097/CJI.0b013e31825898e8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358728PMC
June 2012

Protein L: a novel reagent for the detection of chimeric antigen receptor (CAR) expression by flow cytometry.

J Transl Med 2012 Feb 13;10:29. Epub 2012 Feb 13.

Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1186/1479-5876-10-29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299624PMC
February 2012

The position of the AUG start codon in MFG-based γ-retroviral vectors has a dramatic effect on translation-dependent protein expression.

J Gene Med 2011 Sep;13(9):478-86

Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1002/jgm.1599DOI Listing
September 2011

Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment.

Mol Ther 2011 Apr 1;19(4):751-9. Epub 2011 Feb 1.

Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/mt.2010.313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070103PMC
April 2011

Development of human anti-murine T-cell receptor antibodies in both responding and nonresponding patients enrolled in TCR gene therapy trials.

Clin Cancer Res 2010 Dec;16(23):5852-61

Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-1280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058233PMC
December 2010

Transduction of an HLA-DP4-restricted NY-ESO-1-specific TCR into primary human CD4+ lymphocytes.

J Immunother 2006 Jul-Aug;29(4):398-406

Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1097/01.cji.0000203082.20365.7fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1510955PMC
September 2006

High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation.

Mol Ther 2006 Jan 2;13(1):151-9. Epub 2005 Sep 2.

Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ymthe.2005.07.688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1473967PMC
January 2006

Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR.

J Immunol 2005 Nov;175(9):5799-808

Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1473968PMC
http://dx.doi.org/10.4049/jimmunol.175.9.5799DOI Listing
November 2005

The Chapel Hill hemophilia A dog colony exhibits a factor VIII gene inversion.

Proc Natl Acad Sci U S A 2002 Oct 19;99(20):12991-6. Epub 2002 Sep 19.

Food and Drug Administration, Center for Biologics Evaluation and Research, Rockville, MD 20852, USA.

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http://dx.doi.org/10.1073/pnas.192219599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC130574PMC
October 2002

Inhibition of viral gene expression and replication in mosquito cells by dsRNA-triggered RNA interference.

Mol Ther 2002 Aug;6(2):243-51

National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA.

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http://dx.doi.org/10.1006/mthe.2002.0652DOI Listing
August 2002