Zhijie Chang

Zhijie Chang

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Zhijie Chang

Publications by authors named "Zhijie Chang"

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Mesenchymal stem cells combined with traditional Chinese medicine (qi-fang-bi-min-tang) alleviates rodent allergic rhinitis.

J Cell Biochem 2020 Feb 18;121(2):1541-1551. Epub 2019 Sep 18.

School of Medicine, State Key Laboratory of Membrane Biology, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1002/jcb.29389DOI Listing
February 2020

CREPT Promotes Melanoma Progression Through Accelerated Proliferation and Enhanced Migration by RhoA-Mediated Actin Filaments and Focal Adhesion Formation.

Cancers (Basel) 2019 Dec 20;12(1). Epub 2019 Dec 20.

Laboratory of Experimental Oncology, Department of Pathology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.

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http://dx.doi.org/10.3390/cancers12010033DOI Listing
December 2019

Expression of CREPT is associated with poor prognosis of patients with renal cell carcinoma.

Oncol Lett 2019 Nov 9;18(5):4789-4797. Epub 2019 Sep 9.

Department of Urology, Peking University People's Hospital, The Second Clinical Medical College of Peking University, Beijing 100044, P.R. China.

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http://dx.doi.org/10.3892/ol.2019.10831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781659PMC
November 2019

Identification of novel genetic variants predisposing to familial oral squamous cell carcinomas.

Cell Discov 2019 26;5:57. Epub 2019 Nov 26.

1Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390 USA.

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http://dx.doi.org/10.1038/s41421-019-0126-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877579PMC
November 2019

CREPT is a novel predictor of the response to adjuvant therapy or concurrent chemoradiotherapy in esophageal squamous cell carcinoma.

Int J Clin Exp Pathol 2019 1;12(9):3301-3310. Epub 2019 Sep 1.

The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College Guangdong, P. R. China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949861PMC
September 2019

GdX/UBL4A-knockout mice resist collagen-induced arthritis by balancing the population of T1/T17 and regulatory T cells.

FASEB J 2019 Jul 19;33(7):8375-8385. Epub 2019 Apr 19.

State Key Laboratory of Membrane Biology, School of Medicine, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1096/fj.201802217RRDOI Listing
July 2019

Phosphorylation of proliferating cell nuclear antigen promotes cancer progression by activating the ATM/Akt/GSK3β/Snail signaling pathway.

J Biol Chem 2019 04 11;294(17):7037-7045. Epub 2019 Mar 11.

Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75390

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http://dx.doi.org/10.1074/jbc.RA119.007897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497965PMC
April 2019

HOXB13 networking with ABCG1/EZH2/Slug mediates metastasis and confers resistance to cisplatin in lung adenocarcinoma patients.

Theranostics 2019 6;9(7):2084-2099. Epub 2019 Apr 6.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), and State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing 100191, China.

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http://dx.doi.org/10.7150/thno.29463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485289PMC
April 2019

MicroRNA-383 acts as a tumor suppressor in colorectal cancer by modulating CREPT/RPRD1B expression.

Mol Carcinog 2018 10 3;57(10):1408-1420. Epub 2018 Jul 3.

State Key Laboratory of Membrane Biology, School of Medicine, National Engineering Laboratory for anti-tumor Therapeutics, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1002/mc.22866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324535PMC
October 2018

SAD-A Promotes Glucose-Stimulated Insulin Secretion Through Phosphorylation and Inhibition of GDIα in Male Islet β Cells.

Endocrinology 2018 08;159(8):3036-3047

Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas.

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http://dx.doi.org/10.1210/en.2017-03243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693047PMC
August 2018

CREPT facilitates colorectal cancer growth through inducing Wnt/β-catenin pathway by enhancing p300-mediated β-catenin acetylation.

Oncogene 2018 06 22;37(26):3485-3500. Epub 2018 Mar 22.

Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, Shenzhen Research Institute, The Chinese University of Hong Kong, Sha Tin, Hong Kong.

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http://dx.doi.org/10.1038/s41388-018-0161-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021369PMC
June 2018

WWP2 is a physiological ubiquitin ligase for phosphatase and tensin homolog (PTEN) in mice.

J Biol Chem 2018 06 23;293(23):8886-8899. Epub 2018 Apr 23.

From the State Key Laboratory of Proteomics, National Center of Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing 102206, China,

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http://dx.doi.org/10.1074/jbc.RA117.001060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995496PMC
June 2018

TRIM59 Promotes Gliomagenesis by Inhibiting TC45 Dephosphorylation of STAT3.

Cancer Res 2018 04 31;78(7):1792-1804. Epub 2018 Jan 31.

State Key Laboratory of Oncogenes and Related Genes, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-2774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882560PMC
April 2018

CHIP regulates bone mass by targeting multiple TRAF family members in bone marrow stromal cells.

Bone Res 2018 29;6:10. Epub 2018 Mar 29.

2Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612 USA.

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http://dx.doi.org/10.1038/s41413-018-0010-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874245PMC
March 2018

CREPT and p15RS regulate cell proliferation and cycling in chicken DF-1 cells through the Wnt/β-catenin pathway.

J Cell Biochem 2018 01 23;119(1):1083-1092. Epub 2017 Aug 23.

Key Laboratory of Animal Breeding Reproduction and Molecular Design for Jiangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, P. R. China.

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http://dx.doi.org/10.1002/jcb.26277DOI Listing
January 2018

Histone H1 defect in escort cells triggers germline tumor in Drosophila ovary.

Dev Biol 2017 04 21;424(1):40-49. Epub 2017 Feb 21.

Gene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2017.02.012DOI Listing
April 2017

MFN2 suppresses cancer progression through inhibition of mTORC2/Akt signaling.

Sci Rep 2017 02 8;7:41718. Epub 2017 Feb 8.

Central laboratory, General Surgery, Putuo Hospital, and Interventional Cancer Institute of Chinese Integrative Medicine, Shanghai University of Traditional Chinese Medicine, 164 Lanxi Rd, Shanghai 200062, PR China.

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http://www.nature.com/articles/srep41718
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http://dx.doi.org/10.1038/srep41718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296837PMC
February 2017

Lysyl Oxidase 3 Is a Dual-Specificity Enzyme Involved in STAT3 Deacetylation and Deacetylimination Modulation.

Mol Cell 2017 Jan 5;65(2):296-309. Epub 2017 Jan 5.

Institute of Health Sciences, Chinese Academy of Sciences, Jiaotong University School of Medicine, 320 Yueyang Road, Shanghai 200031, China. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.12.002DOI Listing
January 2017

CD8(+)NKT-like cells regulate the immune response by killing antigen-bearing DCs.

Sci Rep 2015 Sep 15;5:14124. Epub 2015 Sep 15.

Institute of Immunology, Tsinghua University School of Medicine, Beijing 100084, China.

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http://dx.doi.org/10.1038/srep14124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569892PMC
September 2015

CREPT expression correlates with poor prognosis in patients with retroperitoneal leiomyosarcoma.

Int J Clin Exp Pathol 2014 15;7(10):6596-605. Epub 2014 Sep 15.

Department of General Surgery, Chinese PLA General Hospital Beijing 100853, China.

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http://www.ijcep.com/files/ijcep0001163.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230136PMC
July 2015

Nuclear termination of STAT3 signaling through SIPAR (STAT3-Interacting Protein As a Repressor)-dependent recruitment of T cell tyrosine phosphatase TC-PTP.

FEBS Lett 2015 Jul 27;589(15):1890-6. Epub 2015 May 27.

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, Tsinghua University, Beijing 100084, China. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2015.05.031DOI Listing
July 2015

p15RS/RPRD1A (p15INK4b-related sequence/regulation of nuclear pre-mRNA domain-containing protein 1A) interacts with HDAC2 in inhibition of the Wnt/β-catenin signaling pathway.

J Biol Chem 2015 Apr 19;290(15):9701-13. Epub 2015 Feb 19.

From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China, the State Key Laboratory of Biotherapy, Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Sichuan 610041, China,

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http://www.jbc.org/lookup/doi/10.1074/jbc.M114.620872
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http://dx.doi.org/10.1074/jbc.M114.620872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392270PMC
April 2015

Tumor necrosis factor receptor 2 (TNFR2)·interleukin-17 receptor D (IL-17RD) heteromerization reveals a novel mechanism for NF-κB activation.

J Biol Chem 2015 Jan 5;290(2):861-71. Epub 2014 Nov 5.

From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, Tsinghua University, Beijing 100084, China, Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China,

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http://dx.doi.org/10.1074/jbc.M114.586560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294508PMC
January 2015

Characterization of a monoclonal antibody against CREPT, a novel protein highly expressed in tumors.

Monoclon Antib Immunodiagn Immunother 2014 Dec;33(6):401-8

1 State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, Tsinghua University , Beijing, China .

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http://dx.doi.org/10.1089/mab.2014.0043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278082PMC
December 2014

CREPT/RPRD1B, a recently identified novel protein highly expressed in tumors, enhances the β-catenin·TCF4 transcriptional activity in response to Wnt signaling.

J Biol Chem 2014 Aug 30;289(33):22589-99. Epub 2014 Jun 30.

From the State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, the State Key Laboratory of Biotherapy, Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Sichuan 610041, and

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http://www.jbc.org/lookup/doi/10.1074/jbc.M114.560979
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http://dx.doi.org/10.1074/jbc.M114.560979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132767PMC
August 2014

p32, a novel binding partner of Mcl-1, positively regulates mitochondrial Ca(2+) uptake and apoptosis.

Biochem Biophys Res Commun 2014 Aug 1;451(2):322-8. Epub 2014 Aug 1.

Division of Life Science, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.07.122DOI Listing
August 2014

FGFR3 induces degradation of BMP type I receptor to regulate skeletal development.

Biochim Biophys Acta 2014 Jul 20;1843(7):1237-47. Epub 2014 Mar 20.

Center of Bone Metabolism and Repair (CBMR), Trauma Center, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China; State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University, Chongqing 400042, China; Department of Rehabilitation Medicine, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2014.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111238PMC
July 2014

Protein tyrosine phosphatase PTPN9 regulates erythroid cell development through STAT3 dephosphorylation in zebrafish.

J Cell Sci 2014 Jun 11;127(Pt 12):2761-70. Epub 2014 Apr 11.

Beijing Key Laboratory of Cardiometabolic Molecular Medicine and State Key Laboratory of Natural and Biomimetic Drugs, Institute of Molecular Medicine, Peking University, Beijing, 100871 China

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http://dx.doi.org/10.1242/jcs.145367DOI Listing
June 2014

CHIP/Stub1 functions as a tumor suppressor and represses NF-κB-mediated signaling in colorectal cancer.

Carcinogenesis 2014 May 3;35(5):983-91. Epub 2013 Dec 3.

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1093/carcin/bgt393DOI Listing
May 2014

CHIP/Stub1 interacts with eIF5A and mediates its degradation.

Cell Signal 2014 May 6;26(5):1098-104. Epub 2014 Feb 6.

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, Tsinghua University, Beijing 100084, China. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2014.01.030DOI Listing
May 2014

Hsp70 and Hsp90 oppositely regulate TGF-β signaling through CHIP/Stub1.

Biochem Biophys Res Commun 2014 Mar 5;446(1):387-92. Epub 2014 Mar 5.

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, Tsinghua University, Beijing 100084, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.02.124DOI Listing
March 2014

Structural basis for the recognition of RNA polymerase II C-terminal domain by CREPT and p15RS.

Sci China Life Sci 2014 Jan 9;57(1):97-106. Epub 2014 Jan 9.

Ministry of Education Key Laboratory of Protein Science, Center for Structure Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.

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http://dx.doi.org/10.1007/s11427-013-4589-7DOI Listing
January 2014

VEGF189 expression is highly related to adaptation of the plateau pika (Ochotona curzoniae) inhabiting high altitudes.

High Alt Med Biol 2013 Dec;14(4):395-404

1 Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology , The Chinese Academy of Sciences, Xining, China .

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http://dx.doi.org/10.1089/ham.2013.1013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880108PMC
December 2013

SIPAR negatively regulates STAT3 signaling and inhibits progression of melanoma.

Cell Signal 2013 Nov 31;25(11):2272-80. Epub 2013 Jul 31.

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.cellsig.2013.07.023DOI Listing
November 2013

Activation of TAK1 by Sef-S induces apoptosis in 293T cells.

Cell Signal 2013 Oct 11;25(10):2039-46. Epub 2013 Jun 11.

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.cellsig.2013.06.006DOI Listing
October 2013

Glutathione S-transferase M1 null genotype contributes to increased risk of esophageal carcinoma in Chinese population.

Tumour Biol 2013 Aug 28;34(4):2403-7. Epub 2013 Apr 28.

Institute of Biomedicine and School of Medicine, Tsinghua University, Beijing, 100084, People's Republic of China.

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http://dx.doi.org/10.1007/s13277-013-0790-3DOI Listing
August 2013

Inhibitory role of Smad7 in hepatocarcinogenesis in mice and in vitro.

J Pathol 2013 Aug;230(4):441-52

Institute of Digestive Disease and Department of Medicine and Therapeutics, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong.

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http://dx.doi.org/10.1002/path.4206DOI Listing
August 2013

Generation of mice with conditional null allele for GdX/Ubl4A.

Genesis 2012 Jul 24;50(7):534-42. Epub 2012 Jan 24.

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1002/dvg.20832DOI Listing
July 2012

miR-764-5p promotes osteoblast differentiation through inhibition of CHIP/STUB1 expression.

J Bone Miner Res 2012 Jul;27(7):1607-18

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1002/jbmr.1597DOI Listing
July 2012

Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic β-Cells.

J Biol Chem 2012 Jul 5;287(31):26435-44. Epub 2012 Jun 5.

Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 210029, China.

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http://dx.doi.org/10.1074/jbc.M112.378372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406726PMC
July 2012

Rab21 attenuates EGF-mediated MAPK signaling through enhancing EGFR internalization and degradation.

Biochem Biophys Res Commun 2012 May 14;421(4):651-7. Epub 2012 Apr 14.

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, National Engineering Laboratory for Anti-Tumor Therapeutics, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.bbrc.2012.04.049DOI Listing
May 2012

Protein tyrosine phosphatase Meg2 dephosphorylates signal transducer and activator of transcription 3 and suppresses tumor growth in breast cancer.

Breast Cancer Res 2012 Mar 6;14(2):R38. Epub 2012 Mar 6.

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, School of Life Sciences, Tsinghua University, Beijing 100084, China.

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http://breast-cancer-research.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/bcr3134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446372PMC
March 2012

Null genotype of glutathione S-transferase Tl contributes to colorectal cancer risk in the Asian population: a meta-analysis.

J Gastroenterol Hepatol 2012 Feb;27(2):231-7

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1111/j.1440-1746.2011.06920.xDOI Listing
February 2012

CREPT accelerates tumorigenesis by regulating the transcription of cell-cycle-related genes.

Cancer Cell 2012 Jan;21(1):92-104

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1016/j.ccr.2011.12.016DOI Listing
January 2012

Elf3 regulates allergic airway inflammation by controlling dendritic cell-driven T cell differentiation.

J Immunol 2011 Nov 23;187(9):4639-53. Epub 2011 Sep 23.

Physiology and Experimental Medicine Research Program, Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.

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http://dx.doi.org/10.4049/jimmunol.1101967DOI Listing
November 2011

GABARAPL1 negatively regulates Wnt/β-catenin signaling by mediating Dvl2 degradation through the autophagy pathway.

Cell Physiol Biochem 2011 15;27(5):503-12. Epub 2011 Jun 15.

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing, R.P. China.

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http://dx.doi.org/10.1159/000329952DOI Listing
October 2011

Caspase 3 is activated through caspase 8 instead of caspase 9 during H2O2-induced apoptosis in HeLa cells.

Cell Physiol Biochem 2011 15;27(5):539-46. Epub 2011 Jun 15.

School of Medicine, Department of Biological Sciences and Biotechnology, State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1159/000329955DOI Listing
October 2011

[Eukaryotic expression of human IL17-RD-ECD and generation of its monoclonal antibody].

Sheng Wu Gong Cheng Xue Bao 2011 Oct;27(10):1507-12

School of Medicine, Tsinghua University, Beijing 100084, China.

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October 2011

Spata4 promotes osteoblast differentiation through Erk-activated Runx2 pathway.

J Bone Miner Res 2011 Aug;26(8):1964-73

Protein Science Key Laboratory of Ministry of Education, State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, Tsinghua University, Beijing, People's Republic of China.

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http://dx.doi.org/10.1002/jbmr.394DOI Listing
August 2011

Inhibition of B16 murine melanoma metastasis and enhancement of immunity by fever-range whole body hyperthermia.

Int J Hyperthermia 2011 ;27(3):275-85

Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, P.R. China.

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http://www.tandfonline.com/doi/full/10.3109/02656736.2011.55
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http://dx.doi.org/10.3109/02656736.2011.559613DOI Listing
August 2011

SNX25 regulates TGF-β signaling by enhancing the receptor degradation.

Cell Signal 2011 May 23;23(5):935-46. Epub 2011 Jan 23.

Department of Hematology/Oncology, Affiliated Hospital, Hainan Medical College, Hainan (570102), China.

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http://dx.doi.org/10.1016/j.cellsig.2011.01.022DOI Listing
May 2011

Molecular mechanism of the negative regulation of Smad1/5 protein by carboxyl terminus of Hsc70-interacting protein (CHIP).

J Biol Chem 2011 May 16;286(18):15883-94. Epub 2011 Mar 16.

MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1074/jbc.M110.201814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091198PMC
May 2011

p15RS attenuates Wnt/{beta}-catenin signaling by disrupting {beta}-catenin·TCF4 Interaction.

J Biol Chem 2010 Nov 25;285(45):34621-31. Epub 2010 Aug 25.

School of Medicine, School of Life Sciences, State Key Laboratory of Biomembrane and Membrane Biotechnology, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1074/jbc.M110.148791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966078PMC
November 2010

RACK1 promotes Bax oligomerization and dissociates the interaction of Bax and Bcl-XL.

Cell Signal 2010 Oct 10;22(10):1495-501. Epub 2010 Jun 10.

School of Medicine, Department of Biological Sciences and Biotechnology, State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua University, Beijing (100084), China.

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http://dx.doi.org/10.1016/j.cellsig.2010.05.018DOI Listing
October 2010

Development of an inflammation-inducible gene expression system using helper-dependent adenoviral vectors.

J Gene Med 2010 Oct;12(10):832-9

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.1002/jgm.1501DOI Listing
October 2010

A novel function of the human CLS1 in phosphatidylglycerol synthesis and remodeling.

Biochim Biophys Acta 2010 Apr 16;1801(4):438-45. Epub 2009 Dec 16.

Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, 500 University Drive, H166, Hershey, PA 17033, USA.

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http://dx.doi.org/10.1016/j.bbalip.2009.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830748PMC
April 2010

Nuclear protein IkappaB-zeta inhibits the activity of STAT3.

Biochem Biophys Res Commun 2009 Sep 10;387(2):348-52. Epub 2009 Jul 10.

State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, 27 Taiping Road, Beijing 100850, China.

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http://dx.doi.org/10.1016/j.bbrc.2009.07.023DOI Listing
September 2009

[Expression and its Clinical Significance of NOK, EGFR in NSCLC.].

Zhongguo Fei Ai Za Zhi 2009 Sep;12(9):983-8

Department of Thoracic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China.

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http://dx.doi.org/10.3779/j.issn.1009-3419.2009.09.008DOI Listing
September 2009

CHIP functions an E3 ubiquitin ligase of Runx1.

Biochem Biophys Res Commun 2009 Aug 12;386(1):242-6. Epub 2009 Jun 12.

School of Medicine, Department of Biological Sciences and Biotechnology, State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.bbrc.2009.06.043DOI Listing
August 2009

ZNF536, a novel zinc finger protein specifically expressed in the brain, negatively regulates neuron differentiation by repressing retinoic acid-induced gene transcription.

Mol Cell Biol 2009 Jul 27;29(13):3633-43. Epub 2009 Apr 27.

School of Medicine, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1128/MCB.00362-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698762PMC
July 2009

ALCAT1 is a polyglycerophospholipid acyltransferase potently regulated by adenine nucleotide and thyroid status.

Am J Physiol Endocrinol Metab 2009 Apr 23;296(4):E647-53. Epub 2008 Dec 23.

Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, 500 Univ. Dr., H166, Hershey, PA 17033, USA.

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http://dx.doi.org/10.1152/ajpendo.90761.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734525PMC
April 2009

IL-17RD (Sef or IL-17RLM) interacts with IL-17 receptor and mediates IL-17 signaling.

Cell Res 2009 Feb;19(2):208-15

School of Medicine, Department of Biological Sciences and Biotechnology, State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1038/cr.2008.320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603938PMC
February 2009

Varp interacts with Rab38 and functions as its potential effector.

Biochem Biophys Res Commun 2008 Jul 12;372(1):162-7. Epub 2008 May 12.

Key Laboratory of Beijing, College of Life Science, Beijing Normal University, Beijing 100875, China.

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http://dx.doi.org/10.1016/j.bbrc.2008.05.017DOI Listing
July 2008

CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation.

J Cell Biol 2008 Jun 9;181(6):959-72. Epub 2008 Jun 9.

Department of Biological Sciences and Biotechnology, State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, Tsinghua University, Beijing 100084, China.

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http://jcb.rupress.org/content/181/6/959.full.pdf
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http://www.jcb.org/cgi/doi/10.1083/jcb.200711044
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http://dx.doi.org/10.1083/jcb.200711044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426947PMC
June 2008

hSef potentiates EGF-mediated MAPK signaling through affecting EGFR trafficking and degradation.

Cell Signal 2008 Mar 28;20(3):518-33. Epub 2007 Nov 28.

School of Medicine, Department of Biological Sciences and Biotechnology, State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1016/j.cellsig.2007.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514529PMC
March 2008

[Preparation of anti-hNOK antibodies and expression examination of NOK in the lung cancer tissues].

Sheng Wu Gong Cheng Xue Bao 2008 Mar;24(3):480-4

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Medicine, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China.

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March 2008

[Construction and characterization of hSef recombinant adenoviral vectors].

Sheng Wu Gong Cheng Xue Bao 2008 Feb;24(2):193-7

School of Medicine, Department of Biological Sciences and Biotechnology, State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua University, Beijing, China.

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February 2008

[Cloning and expression of human GABARAP and preparation of anti-GABARAP antibodies].

Sheng Wu Gong Cheng Xue Bao 2008 Feb;24(2):245-9

School of Medicine, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China.

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February 2008

Differential ubiquitination of Smad1 mediated by CHIP: implications in the regulation of the bone morphogenetic protein signaling pathway.

J Mol Biol 2007 Nov 3;374(3):777-90. Epub 2007 Oct 3.

Department of Biological Sciences and Biotechnology, State-Key Lab of Biomembranes and Membrane Biotechnology, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.jmb.2007.09.082DOI Listing
November 2007

Interleukin-17F signaling requires ubiquitination of interleukin-17 receptor via TRAF6.

Cell Signal 2007 Jul 6;19(7):1514-20. Epub 2007 Feb 6.

Department of Biological Sciences and Biotechnology, School of Medicine, Institute of Biomedicine, State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.cellsig.2007.01.025DOI Listing
July 2007

The carboxyl terminal tyrosine 417 residue of NOK has an autoinhibitory effect on NOK-mediated signaling transductions.

Biochem Biophys Res Commun 2007 May 8;356(2):444-9. Epub 2007 Mar 8.

Tsinghua Institute of Genome Research, Institute of Biomedicine & School of Medicine, Tsinghua University, Beijing 100084, China.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0700455
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http://dx.doi.org/10.1016/j.bbrc.2007.02.154DOI Listing
May 2007

Therapeutic and prophylactic potential of small interfering RNAs against severe acute respiratory syndrome: progress to date.

BioDrugs 2007 ;21(1):9-15

School of Medicine, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing, China.

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http://link.springer.com/10.2165/00063030-200721010-00002
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http://dx.doi.org/10.2165/00063030-200721010-00002DOI Listing
March 2007

Tyrosine 330 in hSef is critical for the localization and the inhibitory effect on FGF signaling.

Biochem Biophys Res Commun 2007 Mar 18;354(3):741-6. Epub 2007 Jan 18.

Department of Biological Sciences and Biotechnology, School of Medicine, Institute of Biomedicine, State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1016/j.bbrc.2007.01.037DOI Listing
March 2007

Nonnatural protein-protein interaction-pair design by key residues grafting.

Proc Natl Acad Sci U S A 2007 Mar 19;104(13):5330-5. Epub 2007 Mar 19.

Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.

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http://dx.doi.org/10.1073/pnas.0606198104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838465PMC
March 2007

Sef-S, an alternative splice isoform of sef gene, inhibits NIH3T3 cell proliferation via a mitogen-activated protein kinases p42 and p44 (ERK1/2)-independent mechanism.

Cell Signal 2007 Jan 8;19(1):93-102. Epub 2006 Jun 8.

Tsinghua Institute of Genome Research, Department of Biological Sciences and Biotechnology, and School of Medicine, Tsinghua University, Beijing 100084, China.

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http://linkinghub.elsevier.com/retrieve/pii/S089865680600140
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http://dx.doi.org/10.1016/j.cellsig.2006.05.033DOI Listing
January 2007

hSef co-localizes and interacts with Ras in the inhibition of Ras/MAPK signaling pathway.

Biochem Biophys Res Commun 2006 Sep 13;347(4):988-93. Epub 2006 Jul 13.

Tsinghua Institute of Genome Research, Department of Biological Sciences and Biotechnology, and School of Medicine, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.bbrc.2006.06.193DOI Listing
September 2006

Wilms' tumor 1 and signal transducers and activators of transcription 3 synergistically promote cell proliferation: a possible mechanism in sporadic Wilms' tumor.

Cancer Res 2006 Aug;66(16):8049-57

Department of Biological Sciences and Biotechnology and Institute of Biomedicine, Tsinghua University, Beijing 10084, China.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-1172DOI Listing
August 2006

Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics.

J Cell Sci 2006 Mar;119(Pt 6):1053-62

Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing (100084), China.

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http://dx.doi.org/10.1242/jcs.02810DOI Listing
March 2006

CHIP controls the sensitivity of transforming growth factor-beta signaling by modulating the basal level of Smad3 through ubiquitin-mediated degradation.

J Biol Chem 2005 May 21;280(21):20842-50. Epub 2005 Mar 21.

Department of Biological Sciences and Biotechnology, and Institute of Biomedicine, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1074/jbc.M412275200DOI Listing
May 2005

[Different expression of chaperone interacting protein in normal, scar and chronic ulcer tissues and its relationship with wound healing].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2005 Feb;19(2):127-9

Key Research Laboratory of Wound Repair of PLA, 304th Clinical Department, General Hospital of PLA, Beijing, 100037, PR China.

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February 2005

Studies on bone marrow stromal cells affinity of poly (3-hydroxybutyrate-co-3-hydroxyhexanoate).

Biomaterials 2004 Mar-Apr;25(7-8):1365-73

Department of Biological Sciences and Biotechnology, State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.biomaterials.2003.08.018DOI Listing
August 2004

CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription.

Mol Cell Biol 2004 Jan;24(2):856-64

Tsinghua Institute of Genome Research, Department of Biological Sciences and Biotechnology and School of Medicine, Tsinghua University, Beijing 100084, People's Republic of China.

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http://mcb.asm.org/content/24/2/856.full.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC343794PMC
http://dx.doi.org/10.1128/mcb.24.2.856-864.2004DOI Listing
January 2004

A mechanism for Wnt coreceptor activation.

Mol Cell 2004 Jan;13(1):149-56

Division of Neuroscience, Children's Hospital, Department of Neurology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/s1097-2765(03)00484-2DOI Listing
January 2004

hSef inhibits PC-12 cell differentiation by interfering with Ras-mitogen-activated protein kinase MAPK signaling.

J Biol Chem 2003 Dec 4;278(50):50273-82. Epub 2003 Sep 4.

Tsinghua Institute of Genome Research, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084,China.

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http://dx.doi.org/10.1074/jbc.M306936200DOI Listing
December 2003