Zhihong Zeng

Zhihong Zeng

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Zhihong Zeng

Zhihong Zeng

Publications by authors named "Zhihong Zeng"

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49Publications

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Gypenosides mediate cholesterol efflux and suppress oxidized LDL induced inflammation in retinal pigment epithelium cells.

Exp Eye Res 2020 Feb 10;191:107931. Epub 2020 Jan 10.

Department of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow, G4 0BA, UK; Department of Vision Science, Glasgow Caledonian University, Glasgow, G4 0BA, UK. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2020.107931DOI Listing
February 2020

Vitamin D Attenuates Oxidative Damage and Inflammation in Retinal Pigment Epithelial Cells.

Antioxidants (Basel) 2019 Aug 24;8(9). Epub 2019 Aug 24.

Department of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow G4 0BA, UK.

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http://dx.doi.org/10.3390/antiox8090341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770403PMC
August 2019

Efficient Single-Strand Break Repair Requires Binding to Both Poly(ADP-Ribose) and DNA by the Central BRCT Domain of XRCC1.

Cell Rep 2019 01;26(3):573-581.e5

Cancer Research UK DNA Repair Enzymes Group, Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9RQ, UK; Division of Structural Biology, Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW1E 6BT, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183204
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http://dx.doi.org/10.1016/j.celrep.2018.12.082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334254PMC
January 2019

Targeting dihydroorotate dehydrogenase in acute myeloid leukemia.

Haematologica 2018 09;103(9):1415-1417

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

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http://dx.doi.org/10.3324/haematol.2018.197806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119147PMC
September 2018

Role of MSC-derived galectin 3 in the AML microenvironment.

Biochim Biophys Acta Mol Cell Res 2018 07 12;1865(7):959-969. Epub 2018 Apr 12.

Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, United States; Section of Molecular Hematology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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http://dx.doi.org/10.1016/j.bbamcr.2018.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936474PMC
July 2018

Single-Cell Mass Cytometry of Acute Myeloid Leukemia and Leukemia Stem/Progenitor Cells.

Methods Mol Biol 2017 ;1633:75-86

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/978-1-4939-7142-8_5DOI Listing
May 2018

Conditional reprogrammed human limbal epithelial cells represent a novel in vitro cell model for drug responses.

Biochem Biophys Res Commun 2018 05 10;499(4):735-742. Epub 2018 Apr 10.

Shenzhen R&D Center of State Key Laboratory of Virology, Wuhan University Shenzhen Institute, Shenzhen, Guangdong 518057, China; State Key Laboratory of Virology, Institute of Medical Virology, Wuhan University School of Basic Medical Sciences, Wuhan, Hubei 430071, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.03.168DOI Listing
May 2018

TGF-β-Neutralizing Antibody 1D11 Enhances Cytarabine-Induced Apoptosis in AML Cells in the Bone Marrow Microenvironment.

PLoS One 2013 27;8(6):e62785. Epub 2013 Jun 27.

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America ; Department of Clinical Laboratory Medicine, Juntendo University School of Medicine, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062785PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695026PMC
October 2017

Acylpeptide hydrolase is a component of the cellular response to DNA damage.

DNA Repair (Amst) 2017 10 24;58:52-61. Epub 2017 Aug 24.

Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2017.08.008DOI Listing
October 2017

Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin.

Nucleic Acids Res 2017 03;45(5):2546-2557

Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9RQ, UK.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkw1246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389470PMC
March 2017

Ex vivo 2D and 3D HSV-2 infection model using human normal vaginal epithelial cells.

Oncotarget 2017 Feb;8(9):15267-15282

State Key Laboratory of Virology, Institute of Medical Virology, Wuhan University School of Basic Medical Sciences, Wuhan, Hubei 430071, China.

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http://dx.doi.org/10.18632/oncotarget.14840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362485PMC
February 2017

PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2).

Nat Commun 2016 08 17;7:12404. Epub 2016 Aug 17.

Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK.

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http://dx.doi.org/10.1038/ncomms12404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992063PMC
August 2016

The protein phosphatase 2A regulatory subunit B55α is a modulator of signaling and microRNA expression in acute myeloid leukemia cells.

Biochim Biophys Acta 2014 Sep 21;1843(9):1969-77. Epub 2014 May 21.

Division of Molecular Hematology, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Stem Cell Transplantation, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.bbamcr.2014.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165504PMC
September 2014

Preclinical and early clinical evaluation of the oral AKT inhibitor, MK-2206, for the treatment of acute myelogenous leukemia.

Clin Cancer Res 2014 Apr 28;20(8):2226-35. Epub 2014 Feb 28.

Authors' Affiliations: Department of Leukemia; Division of Quantitative Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Division of Hematology/Department of Medicine; Department of Epidemiology, University of Washington, Seattle, Washington; and National Cancer Institute, Rockville, Maryland.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-13-1978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989412PMC
April 2014

Targeting hypoxia in the leukemia microenvironment.

Int J Hematol Oncol 2013 Aug;2(4):279-288

Auckland Cancer Society Research Centre, University of Auckland, Private Bag 92019, Auckland, New Zealand.

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http://dx.doi.org/10.2217/IJH.13.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905090PMC
August 2013

Mitochondrial uncoupling and the reprograming of intermediary metabolism in leukemia cells.

Front Oncol 2013 2;3:67. Epub 2013 Apr 2.

Grupo de Terapia Celular y Molecular Laboratorio de Bioquimica, Pontificia Universidad Javeriana Bogotá, Colombia.

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http://dx.doi.org/10.3389/fonc.2013.00067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613776PMC
April 2013

TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.

Nucleic Acids Res 2012 Sep 26;40(17):8371-80. Epub 2012 Jun 26.

School of Life Sciences, Genome Damage and Stability Centre, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK.

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http://dx.doi.org/10.1093/nar/gks622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458563PMC
September 2012

Functional characterization of the human RPGR proximal promoter.

Invest Ophthalmol Vis Sci 2012 Jun 26;53(7):3951-8. Epub 2012 Jun 26.

Department of Life Sciences, Glasgow Caledonian University, Glasgow, United Kingdom.

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http://dx.doi.org/10.1167/iovs.11-8811DOI Listing
June 2012

TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage.

J Biol Chem 2011 Jan 28;286(1):403-9. Epub 2010 Oct 28.

Genome Damage and Stability Centre, Science Park Road, University of Sussex, Falmer, Brighton, BN1 9RQ, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M110.181016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012998PMC
January 2011

RAP80 acts independently of BRCA1 in repair of topoisomerase II poison-induced DNA damage.

Cancer Res 2010 Nov 19;70(21):8467-74. Epub 2010 Oct 19.

Department of Radiation Genetics, Kyoto University, Graduate School of Medicine, Yoshidakonoe, Sakyo-ku, Kyoto, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0267DOI Listing
November 2010

Therapeutic targeting of microenvironmental interactions in leukemia: mechanisms and approaches.

Drug Resist Updat 2009 Aug-Oct;12(4-5):103-13. Epub 2009 Jul 25.

Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.drup.2009.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640296PMC
March 2010

The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling.

Cancer Res 2007 May;67(9):4210-8

Section of Molecular Hematology and Therapy, Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3629DOI Listing
May 2007

Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias.

Mol Cancer Ther 2006 Dec;5(12):3113-21

Department of Blood and Marrow Transplantation, Section of Molecular Hematology and Therapy, Unit 448, 1515 Holcombe Boulevard, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-06-0228DOI Listing
December 2006

Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies.

Clin Cancer Res 2006 Sep;12(17):5165-73

Authors' Affiliations: Departments of Leukemia and Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-0764DOI Listing
September 2006

The expression and alternative splicing of alpha-neurexins during Xenopus development.

Int J Dev Biol 2006 ;50(1):39-46

School of Pharmacy and Biomedical Sciences, Institute of Biomedical and Biomolecular Sciences, University of Portsmouth, UK.

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http://www.intjdevbiol.com/paper.php?doi=052068zz
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http://dx.doi.org/10.1387/ijdb.052068zzDOI Listing
April 2006

Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia.

Cancer Res 2006 Apr;66(7):3737-46

Section of Molecular Hematology and Therapy, Department of Blood and Marrow Transplantation, The University of Texas M.D. Anderson Cancer Center, 1400 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1278DOI Listing
April 2006

Developmental and tissue expression of Xenopus laevis RPGR.

Invest Ophthalmol Vis Sci 2006 Jan;47(1):348-56

MRC Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1167/iovs.05-0858DOI Listing
January 2006

MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy.

Blood 2005 Nov 12;106(9):3150-9. Epub 2005 Jul 12.

Section of Molecular Hematology and Therapy, Department of Blood and Marrow Transplantation, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Unit 448, Houston, TX 77030, USA.

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http://dx.doi.org/10.1182/blood-2005-02-0553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895324PMC
November 2005

Structure-aided optimization of kinase inhibitors derived from alsterpaullone.

Chembiochem 2005 Mar;6(3):541-9

Institut für Pharmazeutische Chemie, Technische Universität Braunschweig, Beethovenstrasse 55, 38106 Braunschweig, Germany.

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http://dx.doi.org/10.1002/cbic.200400099DOI Listing
March 2005