Zhigang Hong

Zhigang Hong

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Zhigang Hong

Zhigang Hong

Publications by authors named "Zhigang Hong"

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Alveolar Stretch Activation of Endothelial Piezo1 Protects Adherens Junctions and Lung Vascular Barrier.

Am J Respir Cell Mol Biol 2019 Aug 13. Epub 2019 Aug 13.

University of Illinois at Chicago College of Medicine, 12247, Dept of Pharmacology, Chicago, Illinois, United States;

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http://dx.doi.org/10.1165/rcmb.2019-0024OCDOI Listing
August 2019

Hyperpigmentation on the Palm in a Three-year-old Girl: A Quiz.

Acta Derm Venereol 2019 Jun;99(7):715-716

Department of Dermatology, the Fifth Hospital of Jinhua city, 321000 Jinhua, China.

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http://dx.doi.org/10.2340/00015555-3190DOI Listing
June 2019

Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions.

Proc Natl Acad Sci U S A 2019 Jun 11;116(26):12980-12985. Epub 2019 Jun 11.

Department of Pharmacology, University of Illinois College of Medicine, University of Illinois at Chicago, Chicago, IL 60612;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1902165116
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http://dx.doi.org/10.1073/pnas.1902165116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600969PMC
June 2019

Piezo1 mediates angiogenesis through activation of MT1-MMP signaling.

Am J Physiol Cell Physiol 2019 Jan 14;316(1):C92-C103. Epub 2018 Nov 14.

Department of Pharmacology and The Center for Lung and Vascular Biology, The University of Illinois College of Medicine , Chicago, Illinois.

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http://dx.doi.org/10.1152/ajpcell.00346.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383143PMC
January 2019

The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation.

Immunity 2018 07 26;49(1):56-65.e4. Epub 2018 Jun 26.

Department of Pharmacology and the Center for Lung and Vascular Biology, The University of Illinois College of Medicine, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.04.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051907PMC
July 2018

A computational approach to identify cellular heterogeneity and tissue-specific gene regulatory networks.

BMC Bioinformatics 2018 06 7;19(1):217. Epub 2018 Jun 7.

Department of Pharmacology, The University of Illinois College of Medicine, 835 S. Wolcott Ave. Rm. E403, Chicago, IL, 60612, USA.

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http://dx.doi.org/10.1186/s12859-018-2190-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019795PMC
June 2018

Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.

J Clin Invest 2017 Nov 9;127(11):4124-4135. Epub 2017 Oct 9.

Department of Pharmacology, The University of Illinois College of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1172/JCI94495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663346PMC
November 2017

SOX17 Regulates Conversion of Human Fibroblasts Into Endothelial Cells and Erythroblasts by Dedifferentiation Into CD34 Progenitor Cells.

Circulation 2017 Jun 5;135(25):2505-2523. Epub 2017 Apr 5.

From Department of Pharmacology (L.Z., A.J., Z.H., G.M., P.T.T., A.B.M., J.R.), Department of Medicine, Division of Cardiology (J.R.), The University of Illinois College of Medicine, Chicago; and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis (B.-S.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.025722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472005PMC
June 2017

PAR1 Scaffolds TGFβRII to Downregulate TGF-β Signaling and Activate ESC Differentiation to Endothelial Cells.

Stem Cell Reports 2016 12 17;7(6):1050-1058. Epub 2016 Nov 17.

Department of Pharmacology, University of Illinois, College of Medicine, 835 South Wolcott Avenue, Room E403, Chicago, IL 60612, USA; The Center for Lung and Vascular Biology, University of Illinois, College of Medicine, 835 South Wolcott Avenue, Room E403, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161529PMC
December 2016

A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus.

Pflugers Arch 2016 Jan 23;468(1):43-58. Epub 2015 Sep 23.

Department of Medicine, Queen's University, Etherington Hall, Room 3041, 94 Stuart St, Kingston, ON, K7L 3N6, Canada.

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http://link.springer.com/content/pdf/10.1007%2Fs00424-015-17
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http://link.springer.com/10.1007/s00424-015-1736-y
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http://dx.doi.org/10.1007/s00424-015-1736-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703457PMC
January 2016

Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus.

J Mol Med (Berl) 2014 Sep 8;92(9):995-1007. Epub 2014 Jun 8.

Department of Medicine, Queen's University, Etherington Hall, Room 3041, 94 Stuart St., Kingston, Ontario, K7L 3 N6, Canada.

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http://dx.doi.org/10.1007/s00109-014-1162-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134409PMC
September 2014

Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer.

FASEB J 2012 May 9;26(5):2175-86. Epub 2012 Feb 9.

Section of Cardiology, University of Chicago, 5841 South Maryland Ave., MC6080, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1096/fj.11-196543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336787PMC
May 2012

Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle.

J Mol Med (Berl) 2012 Jan 28;90(1):31-43. Epub 2011 Aug 28.

Medicine/Cardiology, University of Chicago, 5841 South Maryland Avenue (MC6080), Chicago, IL 60637, USA.

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http://dx.doi.org/10.1007/s00109-011-0804-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249482PMC
January 2012

A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion.

Am J Respir Crit Care Med 2011 Apr 10;183(8):1080-91. Epub 2010 Dec 10.

Section of Cardiology, Department of Medicine, The University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1164/rccm.201008-1303OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086745PMC
April 2011

The role of ion channels in hypoxic pulmonary vasoconstriction.

Adv Exp Med Biol 2010 ;661:3-14

VA Medical Center, 1 Veterans Drive, 111C, Minneapolis, MN, 55417, USA.

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http://dx.doi.org/10.1007/978-1-60761-500-2_1DOI Listing
April 2010

Acute normoxia increases fetal pulmonary artery endothelial cell cytosolic Ca2+ via Ca2+-induced Ca2+ release.

Pediatr Res 2006 Sep 20;60(3):258-63. Epub 2006 Jul 20.

Department of Pediatrics, Division of Pediatric Pulmonary and Critical Care Medicine, University of Minnesota, Minneapolis, MN 55455, USA.

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http://www.nature.com/doifinder/10.1203/01.pdr.0000233077.29
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http://dx.doi.org/10.1203/01.pdr.0000233077.29866.f0DOI Listing
September 2006

Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus.

Circulation 2006 Sep 18;114(13):1372-9. Epub 2006 Sep 18.

Department of Medicine, VA Medical Center and University of Minnesota, Minneapolis, MN 55417, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.641126DOI Listing
September 2006

Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction.

Circulation 2005 Sep 29;112(10):1494-9. Epub 2005 Aug 29.

Department of Medicine, Veterans Affairs Medical Center, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.105.556704DOI Listing
September 2005

Increased release of serotonin from rat ileum due to dexfenfluramine.

Am J Physiol Regul Integr Comp Physiol 2004 Nov 8;287(5):R1209-13. Epub 2004 Jul 8.

Department of Medicine, Veterans Administration Medical Center, University of Minnesota, Minneapolis 55417, USA.

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http://www.physiology.org/doi/10.1152/ajpregu.00191.2004
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http://dx.doi.org/10.1152/ajpregu.00191.2004DOI Listing
November 2004

Subacute hypoxia decreases voltage-activated potassium channel expression and function in pulmonary artery myocytes.

Am J Respir Cell Mol Biol 2004 Sep 19;31(3):337-43. Epub 2004 May 19.

VA Medical Center, University of Minnesota, Minneapolis, USA.

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http://www.atsjournals.org/doi/abs/10.1165/rcmb.2003-0386OC
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http://dx.doi.org/10.1165/rcmb.2003-0386OCDOI Listing
September 2004

Nordexfenfluramine causes more severe pulmonary vasoconstriction than dexfenfluramine.

Am J Physiol Lung Cell Mol Physiol 2004 Mar 7;286(3):L531-8. Epub 2003 Nov 7.

Veterans Affairs Medical Center, Minneapolis, MN 55417, USA.

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http://dx.doi.org/10.1152/ajplung.00247.2003DOI Listing
March 2004

Low potassium dextran lung preservation solution reduces reactive oxygen species production.

Ann Thorac Surg 2003 Jun;75(6):1705-10

Department of Surgery, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA.

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http://dx.doi.org/10.1016/s0003-4975(03)00173-5DOI Listing
June 2003

Contribution of the K(Ca) channel to membrane potential and O2 sensitivity is decreased in an ovine PPHN model.

Am J Physiol Lung Cell Mol Physiol 2002 Nov;283(5):L1103-9

Department of Anesthesiology, Justus Liebig University, 35392 Giessen, Germany.

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http://dx.doi.org/10.1152/ajplung.00100.2002DOI Listing
November 2002

Graded response of K+ current, membrane potential, and [Ca2+]i to hypoxia in pulmonary arterial smooth muscle.

Am J Physiol Lung Cell Mol Physiol 2002 Nov;283(5):L1143-50

Justus Liebig University, 35392 Giessen, Germany.

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http://www.physiology.org/doi/10.1152/ajplung.00104.2002
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http://dx.doi.org/10.1152/ajplung.00104.2002DOI Listing
November 2002

Redox signaling in oxygen sensing by vessels.

Respir Physiol Neurobiol 2002 Aug;132(1):121-30

Department of Medicine, VA Medical Center, Minneapolis, MN 55417, USA.

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August 2002