Publications


Differences of first-pass effect in the liver and intestine contribute to the stereoselective pharmacokinetics of rhynchophylline and isorhynchophylline epimers in rats.
J Ethnopharmacol 2017 Sep 26;209:175-183. Epub 2017 Jul 26.
Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing 210009, China. Electronic address:

An Unusual Mechanism for Negative Differential Resistance in Ferroelectric Nanocapacitors: Polarization Switching-Induced Charge Injection Followed by Charge Trapping.
ACS Appl Mater Interfaces 2017 Aug 2;9(32):27120-27126. Epub 2017 Aug 2.
Institute for Advanced Materials and Guangdong Provincial Key Laboratory of Quantum Engineering and Quantum Materials, South China Academy of Advanced Optoelectronics, South China Normal University , Guangzhou 510006, China.

Uncoupling the Mitogenic and Metabolic Functions of FGF1 by Tuning FGF1-FGF Receptor Dimer Stability.
Cell Rep 2017 Aug;20(7):1717-1728
Department of Biochemistry & Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA. Electronic address:

[Protective effects of valproic acid on gut barrier function after major burn injury and its mechanism].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2017 Mar;29(3):221-227
Department of Burns and Wound Repair Surgery, Guangdong General Hospital (Guangdong Academy of Medical Sciences), Guangzhou 510080, Guangdong, China (Luo HM, Bian HN, Zheng SY, Xiong B, Huang ZF, Liu ZA, Sun CW, Ma LH, Li HH, Chen HD, Lai W); Laboratory of Shock and Organ Dysfunction, Burn Institute, First Hospital Affiliated to the PLA General Hospital, Beijing 100048, China (Hu S); Department of Critical Care Medicine, Sun Yat-sen Memorial Hospital, Guangzhou 510120, Guangdong, China (Yu W); Department of Emergency, Chinese PLA General Hospital, Beijing 100048, China (Du MH). Corresponding author: Lai Wen, Email:

Tailorable chiroptical activity of metallic nanospiral arrays.
Nanoscale 2016 Feb;8(8):4504-10
Department of Physics, Hong Kong Baptist University (HKBU), Kowloon Tong, Kowloon, Hong Kong SAR, P. R. China. and HKBU Institute of Research and Continuing Education, 9F, the Industrialization Complex of Shenzhen Virtual University Park, No. 2 Yuexing 3rd Road, South Zone, Hi-tech Industrial Park, Nanshan District, Shenzhen, Guangdong Province, P. R. China and Institute of Advanced Materials, HKBU, Kowloon Tong, Kowloon, Hong Kong SAR, P. R. China and Partner State Key Laboratory of Environmental and Biological Analysis, HKBU, Kowloon Tong, Kowloon, HongKong SAR, P. R. China.

Two FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase Cγ.
Mol Cell 2016 Jan 10;61(1):98-110. Epub 2015 Dec 10.
Department of Biochemistry & Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA. Electronic address:

Three-dimensional coherent X-ray diffractive imaging of whole frozen-hydrated cells.
IUCrJ 2015 Sep 20;2(Pt 5):575-83. Epub 2015 Aug 20.
Department of Physics and Astronomy and California NanoSystems Institute, University of California, Los Angeles, CA 90095, USA.

Fibroblast growth factor 21 protects the heart from apoptosis in a diabetic mouse model via extracellular signal-regulated kinase 1/2-dependent signalling pathway.
Diabetologia 2015 Aug 4;58(8):1937-48. Epub 2015 Jun 4.
Chinese-American Research Institute for Diabetic Complication, School of Pharmaceutical Sciences, Wenzhou Medical University, Chashan University-Town, Wenzhou, 325035, People's Republic of China.

Grain rotation and lattice deformation during photoinduced chemical reactions revealed by in situ X-ray nanodiffraction.
Nat Mater 2015 Jul 8;14(7):691-5. Epub 2015 Jun 8.
Department of Physics &Astronomy and California NanoSystems Institute, University of California, Los Angeles, California 90095, USA.


Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.
Nature 2014 Sep 16;513(7518):436-9. Epub 2014 Jul 16.
1] Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA [2] Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, California 92037, USA.

Aqueous and air-compatible fabrication of high-performance conductive textiles.
Chem Asian J 2014 Aug 27;9(8):2170-7. Epub 2014 May 27.
Nanotechnology Centre, Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR (China), Fax: (+852) 27731432; Advanced Research Centre for Fashion and Textiles, The Hong Kong Polytechnic University, Shenzhen Research Institute, Shenzhen (China).

[Effect of bone marrow mesenchymal stem cells on lipopolysacharide-induced secretion of inflammatory cytokines in rat macrophages in vitro].
Nan Fang Yi Ke Da Xue Xue Bao 2014 Aug;34(9):1259-64
1Southern Medical University, Guangzhou 510515, China; 2Department of Burn Surgery, Guangdong General Hospital/Guangdong Academy of Medical Sciences, Guangzhou 510080, China. E-mail:


High-resolution, low-dose phase contrast X-ray tomography for 3D diagnosis of human breast cancers.
Proc Natl Acad Sci U S A 2012 Nov 22;109(45):18290-4. Epub 2012 Oct 22.
Department of Physics and Astronomy and California NanoSystems Institute, University of California, Los Angeles, CA 90095, USA.

Chemical modification of recombinant human keratinocyte growth factor 2 with polyethylene glycol improves biostability and reduces animal immunogenicity.
J Biotechnol 2009 Jul 27;142(3-4):242-9. Epub 2009 May 27.
Key Laboratory of Biotechnology and Pharmaceutical Engineering of Zhejiang Province, Wenzhou Medical College, Wenzhou 325035, China.


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