Publications by authors named "Zhi-dong Zhou"

35Publications

Oxidized nicotinamide adenine dinucleotide-dependent mitochondrial deacetylase sirtuin-3 as a potential therapeutic target of Parkinson's disease.

Ageing Res Rev 2020 Sep 12;62:101107. Epub 2020 Jun 12.

National Neuroscience Institute, 11 Jalan Tan Tock Seng, 308433, Singapore; Department of Neurology, Singapore General Hospital, Outram Road, 169608, Singapore; Duke-NUS Graduate Medical School, 8 College Road, 169857, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2020.101107DOI Listing
September 2020

Molecular targets for modulating the protein translation vital to proteostasis and neuron degeneration in Parkinson's disease.

Transl Neurodegener 2019 4;8. Epub 2019 Feb 4.

1Department of Research, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore, 308433 Singapore.

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http://dx.doi.org/10.1186/s40035-019-0145-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360798PMC
February 2019

Pathophysiological mechanisms linking F-box only protein 7 (FBXO7) and Parkinson's disease (PD).

Mutat Res 2018 Oct - Dec;778:72-78. Epub 2018 Oct 17.

Department of Research, National Neuroscience Institute, 11 Jalan Tan Tock Seng, 308433, Singapore; Department of Neurology, Singapore General Hospital, Outram Road, 169608, Singapore; Signature Research Program in Neuroscience and Behavioural Disorders, Duke-NUS Medical School, 8 College Road, 169857, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.mrrev.2018.10.001DOI Listing
April 2019

Iron regulatory protein (IRP)-iron responsive element (IRE) signaling pathway in human neurodegenerative diseases.

Mol Neurodegener 2017 10 23;12(1):75. Epub 2017 Oct 23.

National Neuroscience Institute of Singapore, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.

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http://dx.doi.org/10.1186/s13024-017-0218-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654065PMC
October 2017

LRRK2 interacts with ATM and regulates Mdm2-p53 cell proliferation axis in response to genotoxic stress.

Hum Mol Genet 2017 11;26(22):4494-4505

Neural Stem Cell Research Lab, Research Department, National Neuroscience Institute, Singapore 308433.

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http://dx.doi.org/10.1093/hmg/ddx337DOI Listing
November 2017

Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease.

Sci Signal 2017 Jul 18;10(488). Epub 2017 Jul 18.

Research Department, National Neuroscience Institute, Singapore General Hospital (SGH) Campus, Singapore 169856, Singapore.

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http://dx.doi.org/10.1126/scisignal.aam6790DOI Listing
July 2017

p62-Mediated mitochondrial clustering attenuates apoptosis induced by mitochondrial depolarization.

Biochim Biophys Acta Mol Cell Res 2017 Jul 19;1864(7):1308-1317. Epub 2017 Apr 19.

Department of Neurology, National Neuroscience Institute, Singapore; Department of Neurology, Singapore General Hospital, Singapore; Duke-NUS Graduate Medical School, National University of Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2017.04.009DOI Listing
July 2017

Erratum to: Mitochondrial CHCHD-Containing Proteins: Physiologic Functions and Link with Neurodegenerative Diseases.

Mol Neurobiol 2017 09;54(7):5547-5549

National Neuroscience Institute of Singapore, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.

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http://dx.doi.org/10.1007/s12035-016-0160-4DOI Listing
September 2017

Mitochondrial CHCHD-Containing Proteins: Physiologic Functions and Link with Neurodegenerative Diseases.

Mol Neurobiol 2017 09 8;54(7):5534-5546. Epub 2016 Sep 8.

National Neuroscience Institute of Singapore, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.

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http://dx.doi.org/10.1007/s12035-016-0099-5DOI Listing
September 2017

Posterior pericardiotomy for the prevention of atrial fibrillation after coronary artery bypass grafting: A meta-analysis of randomized controlled trials.

Int J Cardiol 2016 Jul 16;215:252-6. Epub 2016 Apr 16.

Department of Anesthesiology, The Second Affiliated Hospital to Nanchang University, Nanchang 330006, Jiangxi Province, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.04.081DOI Listing
July 2016

Linking F-box protein 7 and parkin to neuronal degeneration in Parkinson's disease (PD).

Mol Brain 2016 Apr 18;9:41. Epub 2016 Apr 18.

National Neuroscience Institute of Singapore, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.

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http://dx.doi.org/10.1186/s13041-016-0218-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835861PMC
April 2016

Antioxidants inhibit neuronal toxicity in Parkinson's disease-linked LRRK2.

Ann Clin Transl Neurol 2016 04 2;3(4):288-94. Epub 2016 Mar 2.

Department of Neurology Singapore General Hospital 20 College Rd The Academia Discovery Tower Singapore 169856; National Neuroscience Institute 11 Tan Tock Seng Singapore 308433; Duke-NUS Graduate Medical School 8 College Rd Singapore 169857.

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http://dx.doi.org/10.1002/acn3.282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818746PMC
April 2016

F-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagy.

Hum Mol Genet 2015 Nov 26;24(22):6314-30. Epub 2015 Aug 26.

National Neuroscience Institute of Singapore, 11 Jalan Tan Tock Seng, Singapore, Singapore, Signature Research Program in Neuroscience and Behavioral Disorders, Duke-NUS Graduate Medical School Singapore, 8 College Road, Singapore, Singapore, Department of Neurology, Singapore General Hospital, Outram Road, Singapore, Singapore and

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http://dx.doi.org/10.1093/hmg/ddv340DOI Listing
November 2015

Association Analysis of COQ2 Variant in Dementia and Essential Tremor.

Parkinsons Dis 2015 22;2015:926280. Epub 2015 Apr 22.

Department of Neurology, Singapore General Hospital, Singapore 169608 ; National Neuroscience Institute, Singapore 308433 ; Duke-NUS Graduate Medical School, Singapore 169857 ; Department of Clinical Research, Singapore General Hospital, Singapore 169608.

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http://dx.doi.org/10.1155/2015/926280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421028PMC
May 2015

Thiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in Drosophila.

Hum Mol Genet 2014 Jun 23;23(12):3157-65. Epub 2014 Jan 23.

Department of Neurology, Singapore General Hospital, Singapore, Singapore 169856 National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore, Singapore 308433 Duke-NUS Graduate Medical School, 8 College Road, Singapore, Singapore 169857

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http://dx.doi.org/10.1093/hmg/ddu026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030771PMC
June 2014

Mutant PINK1 upregulates tyrosine hydroxylase and dopamine levels, leading to vulnerability of dopaminergic neurons.

Free Radic Biol Med 2014 Mar 25;68:220-33. Epub 2013 Dec 25.

National Neuroscience Institute, Singapore 308433, Singapore; Duke-National University of Singapore Graduate Medical School, Singapore 169857, Singapore; Department of Neurology, Singapore General Hospital, Singapore 169608, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2013.12.015DOI Listing
March 2014

[Effect of Achyranthes bidentata polysaccharides stimulated dendritic cells co-cultured with cytokine induced killer cells against SW480 cells].

Zhongguo Zhong Yao Za Zhi 2013 Apr;38(7):1056-60

Department of Immunology, Taizhou University, Taizhou 318000, China.

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April 2013

LINGO-1 and Neurodegeneration: Pathophysiologic Clues for Essential Tremor.

Tremor Other Hyperkinet Mov (N Y) 2012 20;2. Epub 2012 Feb 20.

National Neuroscience Institute, Singapore 308433.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569903PMC
http://dx.doi.org/10.7916/D8PZ57JVDOI Listing
July 2013

Iron species-mediated dopamine oxidation, proteasome inhibition, and dopaminergic cell demise: implications for iron-related dopaminergic neuron degeneration.

Free Radic Biol Med 2010 Dec 18;49(12):1856-71. Epub 2010 Sep 18.

Department of Biological Science, National University of Singapore, Singapore.

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http://dx.doi.org/10.1016/j.freeradbiomed.2010.09.010DOI Listing
December 2010

Glutathione conjugates with dopamine-derived quinones to form reactive or non-reactive glutathione-conjugates.

Neurochem Res 2010 Nov 19;35(11):1805-18. Epub 2010 Aug 19.

Department of Biological Science, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1007/s11064-010-0247-7DOI Listing
November 2010

Notch as a molecular switch in neural stem cells.

IUBMB Life 2010 Aug;62(8):618-23

National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore.

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http://dx.doi.org/10.1002/iub.362DOI Listing
August 2010

Notch as a molecular switch in neural stem cells.

IUBMB Life 2010 Aug;62(8):spcone

National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433.

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http://dx.doi.org/10.1002/iub.372DOI Listing
August 2010

Dopamine (DA) induced irreversible proteasome inhibition via DA derived quinones.

Free Radic Res 2009 Apr 17;43(4):417-30. Epub 2009 Mar 17.

Department of Biological Science, National University of Singapore, 14 Science Drive 4, Singapore 117543.

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http://dx.doi.org/10.1080/10715760902801533DOI Listing
April 2009

Dopamine auto-oxidation aggravates non-apoptotic cell death induced by over-expression of human A53T mutant alpha-synuclein in dopaminergic PC12 cells.

J Neurochem 2009 Feb 27;108(3):601-10. Epub 2008 Nov 27.

Department of Biological Science, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1111/j.1471-4159.2008.05795.xDOI Listing
February 2009

Roles of glutathione (GSH) in dopamine (DA) oxidation studied by improved tandem HPLC plus ESI-MS.

Neurochem Res 2009 Feb 5;34(2):316-26. Epub 2008 Jul 5.

Department of Biological Science, National University of Singapore, 14 Science Drive 4, Singapore, Singapore, 117543.

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http://dx.doi.org/10.1007/s11064-008-9778-6DOI Listing
February 2009

[Surface markers and functions of human dendritic cells exposed to mobile phone 1800 MHz electromagnetic fields].

Zhejiang Da Xue Xue Bao Yi Xue Ban 2008 Jan;37(1):29-33

Institute of Immunology, College of Medicine, Zhejiang University, Hangzhou 310058, China.

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January 2008

[Study on effect of lentinan in enhancing anti-tumor action of dendritic cytoma vaccine and its mechanism].

Zhongguo Zhong Xi Yi Jie He Za Zhi 2007 Jan;27(1):60-4

Hangzhou Red Cross Hospital, Zhejiang.

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January 2007

Chromium (III) enhanced diamine silver staining of proteins and DNA in gels.

Biotechnol Lett 2003 Nov;25(21):1801-4

State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, PR China.

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http://dx.doi.org/10.1023/a:1026280519327DOI Listing
November 2003

Low content of protein S29 in ribosomes of human lung cancer cell line a549: detected by two-dimensional electrophoresis.

Protein Pept Lett 2003 Feb;10(1):91-7

State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China.

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http://dx.doi.org/10.2174/0929866033408273DOI Listing
February 2003