Zhi-xiu Lin

Zhi-xiu Lin

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Zhi-xiu Lin

Publications by authors named "Zhi-xiu Lin"

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Huang-Lian-Jie-Du extract ameliorates atopic dermatitis-like skin lesions induced by 2,4-dinitrobenzene in mice via suppression of MAPKs and NF-κB pathways.

J Ethnopharmacol 2020 Mar 31;249:112367. Epub 2019 Oct 31.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, China; Brain Research Centre, School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China; Institute of Integrative Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2019.112367DOI Listing
March 2020

Origins of Beta Amyloid Differ Between Vascular Amyloid Deposition and Parenchymal Amyloid Plaques in the Spinal Cord of a Mouse Model of Alzheimer's Disease.

Mol Neurobiol 2020 Jan 19;57(1):278-289. Epub 2019 Jul 19.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, Hong Kong.

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http://dx.doi.org/10.1007/s12035-019-01697-4DOI Listing
January 2020

Apoptosis induced by bruceine D in human non‑small‑cell lung cancer cells involves mitochondrial ROS‑mediated death signaling.

Int J Mol Med 2019 Dec 3;44(6):2015-2026. Epub 2019 Oct 3.

Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510120, P.R. China.

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http://dx.doi.org/10.3892/ijmm.2019.4363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844635PMC
December 2019

Berberine enhances survival and axonal regeneration of motoneurons following spinal root avulsion and re-implantation in rats.

Free Radic Biol Med 2019 Nov 28;143:454-470. Epub 2019 Aug 28.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, 999077, China; Brain Research Centre, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, 999077, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08915849193098
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http://dx.doi.org/10.1016/j.freeradbiomed.2019.08.029DOI Listing
November 2019

Isorhynchophylline ameliorates cognitive impairment via modulating amyloid pathology, tau hyperphosphorylation and neuroinflammation: Studies in a transgenic mouse model of Alzheimer's disease.

Brain Behav Immun 2019 Nov 30;82:264-278. Epub 2019 Aug 30.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region; Brain Research Centre, School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region; Hong Kong Institute of Integrative Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2019.08.194DOI Listing
November 2019

Isorhynchophylline exerts antidepressant-like effects in mice modulating neuroinflammation and neurotrophins: involvement of the PI3K/Akt/GSK-3β signaling pathway.

FASEB J 2019 Sep 24;33(9):10393-10408. Epub 2019 Jun 24.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1096/fj.201802743RRDOI Listing
September 2019

Prenylated xanthones and biphenyls from with antistaphylococcal activity.

Nat Prod Res 2019 Sep 12:1-8. Epub 2019 Sep 12.

School of Pharmacy, Shanghai University of Traditional Chinese Medicine , Shanghai , People's Republic of China.

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http://dx.doi.org/10.1080/14786419.2019.1663511DOI Listing
September 2019

Brusatol, a Nrf2 Inhibitor Targets STAT3 Signaling Cascade in Head and Neck Squamous Cell Carcinoma.

Biomolecules 2019 09 30;9(10). Epub 2019 Sep 30.

College of Korean Medicine, Kyung Hee University, #47, Kyungheedae-gil, Dongdaemoon-gu, Seoul 130-701, Korea.

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http://dx.doi.org/10.3390/biom9100550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843503PMC
September 2019

Uncaria rhynchophylla and Its Major Constituents on Central Nervous System: A Review on Their Pharmacological Actions.

Curr Vasc Pharmacol 2019 Jul 3. Epub 2019 Jul 3.

School of Chinese Medicine, The Chinese University of Hong Kong. Hong Kong.

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http://dx.doi.org/10.2174/1570161117666190704092841DOI Listing
July 2019

Therapeutic effect of Brucea javanica oil emulsion on experimental Crohn's disease in rats: Involvement of TLR4/ NF-κB signaling pathway.

Biomed Pharmacother 2019 Jun 20;114:108766. Epub 2019 Mar 20.

Guangdong Provincial Key Laboratory of New Drug Development and Research of Chinese Medicine, Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2019.108766DOI Listing
June 2019

Pharmacokinetic study on bruceoside A revealed the potential role of quassinoid glycosides for the anticancer properties of Fructus Bruceae.

J Pharm Biomed Anal 2019 Jun 23;170:264-272. Epub 2019 Mar 23.

Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2019.03.052DOI Listing
June 2019

Association Between Axonopathy and Amyloid Plaques in the Spinal Cord of the Transgenic Mice of Alzheimer's Disease.

Neuroscience 2019 06 26;409:152-161. Epub 2019 Apr 26.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong; Brain Research Centre, Faculty of Medicine, The Chinese University of Hong Kong. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2019.04.037DOI Listing
June 2019

Ameliorative effect of supercritical fluid extract of Chrysanthemum indicum Linnén against D-galactose induced brain and liver injury in senescent mice via suppression of oxidative stress, inflammation and apoptosis.

J Ethnopharmacol 2019 Apr 2;234:44-56. Epub 2019 Jan 2.

Guangdong Provincial Key Laboratory of New Drug Development and Research of Chinese Medicine, Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2018.12.050DOI Listing
April 2019

Evaluation of the safety profiles of estrogenic Chinese herbal medicines in breast cancer.

Phytomedicine 2019 Mar 8;56:103-117. Epub 2018 Oct 8.

Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong; State Key Laboratory of Phytochemistry and Plant Resources in West China (CUHK), The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09447113183052
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http://dx.doi.org/10.1016/j.phymed.2018.10.003DOI Listing
March 2019

Evidence on Integrating Pharmacokinetics to Find Truly Therapeutic Agent for Alzheimer's Disease: Comparative Pharmacokinetics and Disposition Kinetics Profiles of Stereoisomers Isorhynchophylline and Rhynchophylline in Rats.

Evid Based Complement Alternat Med 2019 3;2019:4016323. Epub 2019 Feb 3.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong.

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http://dx.doi.org/10.1155/2019/4016323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377964PMC
February 2019

Self-nanoemulsifying drug delivery system of bruceine D: a new approach for anti-ulcerative colitis.

Int J Nanomedicine 2018 28;13:5887-5907. Epub 2018 Sep 28.

Department of Pharmacy, The First Affiliated Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China,

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http://dx.doi.org/10.2147/IJN.S174146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167998PMC
November 2018

Comparison of the anti-inflammatory effects of Sinapis alba and Brassica juncea in mouse models of inflammation.

Phytomedicine 2018 Nov 19;50:196-204. Epub 2018 May 19.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2018.05.010DOI Listing
November 2018

Moxibustion for alleviating side effects of chemotherapy or radiotherapy in people with cancer.

Cochrane Database Syst Rev 2018 Nov 13;11:CD010559. Epub 2018 Nov 13.

School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.

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http://doi.wiley.com/10.1002/14651858.CD010559.pub2
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http://dx.doi.org/10.1002/14651858.CD010559.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517257PMC
November 2018

Curcumin's Metabolites, Tetrahydrocurcumin and Octahydrocurcumin, Possess Superior Anti-inflammatory Effects Through Suppression of TAK1-NF-κB Pathway.

Front Pharmacol 2018 17;9:1181. Epub 2018 Oct 17.

Guangdong Provincial Key Laboratory of New Drug Development and Research of Chinese Medicine, Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.

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http://dx.doi.org/10.3389/fphar.2018.01181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199526PMC
October 2018

Angelica sinensis Supercritical Fluid CO Extract Attenuates D-Galactose-Induced Liver and Kidney Impairment in Mice by Suppressing Oxidative Stress and Inflammation.

J Med Food 2018 Sep 15;21(9):887-898. Epub 2018 Aug 15.

4 Shenzhen Key Laboratory of Hospital Chinese Medicine Preparation, Shenzhen Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine , Shenzhen, China .

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http://dx.doi.org/10.1089/jmf.2017.4061DOI Listing
September 2018

Complete Chloroplast Genomes from : Identity and Variation Among Four Species.

Molecules 2018 Aug 24;23(9). Epub 2018 Aug 24.

Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

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http://www.mdpi.com/1420-3049/23/9/2137
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http://dx.doi.org/10.3390/molecules23092137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225366PMC
August 2018

Effectiveness and safety of acupuncture for elderly overactive bladder population in Hong Kong: study protocol for a randomized controlled trial.

Trials 2018 Jul 13;19(1):376. Epub 2018 Jul 13.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.

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http://dx.doi.org/10.1186/s13063-018-2706-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045827PMC
July 2018

The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer.

Oncotarget 2018 06 5;9(43):27104-27116. Epub 2018 Jun 5.

MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.18632/oncotarget.25497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007465PMC
June 2018

Isorhynchophylline alleviates learning and memory impairments induced by aluminum chloride in mice.

Chin Med 2018 14;13:29. Epub 2018 Jun 14.

1School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR People's Republic of China.

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http://dx.doi.org/10.1186/s13020-018-0187-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000983PMC
June 2018

Synergistic antitumor effect of brusatol combined with cisplatin on colorectal cancer cells.

Int J Mol Med 2018 Mar 9;41(3):1447-1454. Epub 2018 Jan 9.

College of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, P.R. China.

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http://dx.doi.org/10.3892/ijmm.2018.3372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819912PMC
March 2018

The Therapeutic Effects of a Traditional Chinese Medicine Formula Wuzi Yanzong Pill for the Treatment of Oligoasthenozoospermia: A Meta-Analysis of Randomized Controlled Trials.

Evid Based Complement Alternat Med 2018 17;2018:2968025. Epub 2018 Jan 17.

Department of Obstetrics and Gynecology, Prince of Wales Hospital, The Chinese University of Hong Kong, Sha Tin, Hong Kong.

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http://dx.doi.org/10.1155/2018/2968025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822795PMC
January 2018

Motor deficits are independent of axonopathy in an Alzheimer's disease mouse model of TgCRND8 mice.

Oncotarget 2017 Nov 9;8(58):97900-97912. Epub 2017 Jun 9.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.18632/oncotarget.18429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716700PMC
November 2017

Exploring brusatol as a new anti-pancreatic cancer adjuvant: biological evaluation and mechanistic studies.

Oncotarget 2017 Oct 10;8(49):84974-84985. Epub 2017 May 10.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, China.

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http://dx.doi.org/10.18632/oncotarget.17761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689587PMC
October 2017

Protective Effect of SFE-CO of Ligusticum chuanxiong Hort Against d-Galactose-Induced Injury in the Mouse Liver and Kidney.

Rejuvenation Res 2017 Jun 23;20(3):231-243. Epub 2017 Feb 23.

1 Guangdong Provincial Key Laboratory of New Chinese Medicinals Development and Research, Guangzhou University of Chinese Medicine , Guangzhou, P.R. China .

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http://dx.doi.org/10.1089/rej.2016.1870DOI Listing
June 2017

Dalbergia odorifera extract promotes angiogenesis through upregulation of VEGFRs and PI3K/MAPK signaling pathways.

J Ethnopharmacol 2017 May 12;204:132-141. Epub 2017 Apr 12.

Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03788741163231
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http://dx.doi.org/10.1016/j.jep.2017.04.006DOI Listing
May 2017

Antidepressant-Like Effect of Isorhynchophylline in Mice.

Neurochem Res 2017 Feb 30;42(2):678-685. Epub 2016 Nov 30.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, People's Republic of China.

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http://link.springer.com/10.1007/s11064-016-2124-5
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http://dx.doi.org/10.1007/s11064-016-2124-5DOI Listing
February 2017

Anti-inflammatory effects of Brucea javanica oil emulsion by suppressing NF-κB activation on dextran sulfate sodium-induced ulcerative colitis in mice.

J Ethnopharmacol 2017 Feb 22;198:389-398. Epub 2017 Jan 22.

Guangdong Provincial Key Laboratory of New Chinese Medicinal Development and Research, College of Chinese Medicines, Guangzhou University of Chinese Medicine, Guangzhou 510006, People's Republic of China; Dongguan Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Songshan Hu Industrial Park, Dongguan 523808, Guangdong, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2017.01.042DOI Listing
February 2017

Effects of Ginkgo biloba on dementia: An overview of systematic reviews.

J Ethnopharmacol 2017 Jan 7;195:1-9. Epub 2016 Dec 7.

School of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2016.12.005DOI Listing
January 2017

Effectiveness and Safety of Acupuncture for Poststroke Dysphagia: Study Protocol for a Pragmatic Multicenter Nonrandomized Controlled Trial.

Evid Based Complement Alternat Med 2017 29;2017:2349794. Epub 2017 Jan 29.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.

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http://dx.doi.org/10.1155/2017/2349794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303584PMC
January 2017

Attenuation of blood pressure in spontaneously hypertensive rats by acupuncture was associated with reduction oxidative stress and improvement from endothelial dysfunction.

Chin Med 2016 30;11(1):38. Epub 2016 Aug 30.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1186/s13020-016-0110-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006281PMC
September 2016

Neuroprotective effects of honokiol against beta-amyloid-induced neurotoxicity via GSK-3β and β-catenin signaling pathway in PC12 cells.

Neurochem Int 2016 07 27;97:8-14. Epub 2016 Apr 27.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong Special Administrative Region. Electronic address:

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http://dx.doi.org/10.1016/j.neuint.2016.04.014DOI Listing
July 2016

Anti-inflammatory and anti-allergic effects and underlying mechanisms of Huang-Lian-Jie-Du extract: Implication for atopic dermatitis treatment.

J Ethnopharmacol 2016 Jun 11;185:41-52. Epub 2016 Mar 11.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2016.03.028DOI Listing
June 2016

Xiaoke Pill () and anti-diabetic drugs: A review on clinical evidence of possible herb-drug interactions.

Chin J Integr Med 2016 Jan 29. Epub 2016 Jan 29.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1007/s11655-015-2106-5DOI Listing
January 2016

An overview on adverse drug reactions to traditional Chinese medicines.

Br J Clin Pharmacol 2015 Oct 19;80(4):834-43. Epub 2015 May 19.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.

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http://dx.doi.org/10.1111/bcp.12598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594726PMC
October 2015

Honokiol improves learning and memory impairments induced by scopolamine in mice.

Eur J Pharmacol 2015 Aug 23;760:88-95. Epub 2015 Apr 23.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2015.04.013DOI Listing
August 2015

Characterization of solid dispersions of Patchouli alcohol with different polymers: effects on the inhibition of reprecipitation and the improvement of dissolution rate.

Drug Dev Ind Pharm 2015 Mar 13;41(3):436-44. Epub 2014 Jan 13.

School of Chinese Materia Medica, Guangzhou University of Chinese Medicine , Guangzhou , China .

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http://dx.doi.org/10.3109/03639045.2013.877482DOI Listing
March 2015

Protective effects of pogostone from Pogostemonis Herba against ethanol-induced gastric ulcer in rats.

Fitoterapia 2015 Jan 3;100:110-7. Epub 2014 Dec 3.

College of Chinese Medicines, Guangzhou University of Chinese Medicine, Guangzhou 510006, People's Republic of China; Dongguan Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Dongguan 523808, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2014.11.017DOI Listing
January 2015

Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease.

Cochrane Database Syst Rev 2014 Dec 18(12):CD008353. Epub 2014 Dec 18.

School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.

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http://dx.doi.org/10.1002/14651858.CD008353.pub2DOI Listing
December 2014

Pogostone suppresses proinflammatory mediator production and protects against endotoxic shock in mice.

J Ethnopharmacol 2014 Nov 26;157:212-21. Epub 2014 Sep 26.

College of Chinese Medicines, Guangzhou University of Chinese Medicine, 232 Wai Huan Dong Road, Guangzhou Higher Education Mega Center, Guangzhou 510006, PR China; Dongguan Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Dongguan 523808, PR China. Electronic address:

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http://ac.els-cdn.com/S0378874114006771/1-s2.0-S037887411400
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http://linkinghub.elsevier.com/retrieve/pii/S037887411400677
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http://dx.doi.org/10.1016/j.jep.2014.09.023DOI Listing
November 2014

Isorhynchophylline treatment improves the amyloid-β-induced cognitive impairment in rats via inhibition of neuronal apoptosis and tau protein hyperphosphorylation.

J Alzheimers Dis 2014 ;39(2):331-46

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.

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http://dx.doi.org/10.3233/JAD-131457DOI Listing
October 2014

Isorhynchophylline improves learning and memory impairments induced by D-galactose in mice.

Neurochem Int 2014 Oct 28;76:42-9. Epub 2014 Jun 28.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuint.2014.06.011DOI Listing
October 2014

Effects of topical application of patchouli alcohol on the UV-induced skin photoaging in mice.

Eur J Pharm Sci 2014 Oct 14;63:113-23. Epub 2014 Jul 14.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region. Electronic address:

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http://dx.doi.org/10.1016/j.ejps.2014.07.001DOI Listing
October 2014

Astragalus (a traditional Chinese medicine) for treating chronic kidney disease.

Cochrane Database Syst Rev 2014 Oct 22(10):CD008369. Epub 2014 Oct 22.

School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.

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http://dx.doi.org/10.1002/14651858.CD008369.pub2DOI Listing
October 2014

Mechanistic studies of anti-hyperpigmentary compounds: elucidating their inhibitory and regulatory actions.

Int J Mol Sci 2014 Aug 21;15(8):14649-68. Epub 2014 Aug 21.

School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.

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http://dx.doi.org/10.3390/ijms150814649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159873PMC
August 2014

Induction of phosphorylated c-Jun in neonatal spinal motoneurons after axonal injury is coincident with both motoneuron death and regeneration.

J Anat 2014 May 7;224(5):575-82. Epub 2014 Feb 7.

Faculty of Medicine, School of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, China; Department of Anatomy, University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1111/joa.12165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981500PMC
May 2014

Assessment of the rate of spinal motor axon regeneration by choline acetyltransferase immunohistochemistry following sciatic nerve crush injury in mice.

J Neurosurg 2014 Feb 13;120(2):502-8. Epub 2013 Sep 13.

School of Chinese Medicine, Faculty of Science, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China;

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http://dx.doi.org/10.3171/2013.8.JNS121648DOI Listing
February 2014

Amyloid pathology in spinal cord of the transgenic Alzheimer's disease mice is correlated to the corticospinal tract pathway.

J Alzheimers Dis 2013 ;35(4):675-85

Faculty of Science, School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, China.

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http://dx.doi.org/10.3233/JAD-122323DOI Listing
December 2013

Isorhynchophylline Protects PC12 Cells Against Beta-Amyloid-Induced Apoptosis via PI3K/Akt Signaling Pathway.

Evid Based Complement Alternat Med 2013 6;2013:163057. Epub 2013 Nov 6.

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.

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http://downloads.hindawi.com/journals/ecam/2013/163057.pdf
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http://www.hindawi.com/journals/ecam/2013/163057/
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http://dx.doi.org/10.1155/2013/163057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836301PMC
December 2013

Contrasting neuropathology and functional recovery after spinal cord injury in developing and adult rats.

Neurosci Bull 2013 Aug 11;29(4):509-16. Epub 2013 Jul 11.

Department of Anatomy, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.

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http://dx.doi.org/10.1007/s12264-013-1356-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561938PMC
August 2013

1,4-dihydroxy-2-naphthoic Acid Induces Apoptosis in Human Keratinocyte: Potential Application for Psoriasis Treatment.

Evid Based Complement Alternat Med 2013 11;2013:792840. Epub 2013 Apr 11.

School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.

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http://dx.doi.org/10.1155/2013/792840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638593PMC
July 2013

Protective effects of hydroxysafflor yellow A on β-amyloid-induced neurotoxicity in PC12 cells.

Neurochem Res 2013 May 19;38(5):951-60. Epub 2013 Feb 19.

School of Chinese Materia Medica, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.

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http://dx.doi.org/10.1007/s11064-013-1002-7DOI Listing
May 2013

Existence of different types of senile plaques between brain and spinal cord of TgCRND8 mice.

Neurochem Int 2013 Feb 17;62(3):211-20. Epub 2013 Jan 17.

School of Chinese Medicine, Faculty of Science, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.

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http://dx.doi.org/10.1016/j.neuint.2013.01.006DOI Listing
February 2013

Comparison the neuropreotective effect of Cortex Phellodendri chinensis and Cortex Phellodendri amurensis against beta-amyloid-induced neurotoxicity in PC12 cells.

Phytomedicine 2013 Jan 2;20(2):187-93. Epub 2012 Nov 2.

School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong Special Administrative Region.

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http://dx.doi.org/10.1016/j.phymed.2012.09.028DOI Listing
January 2013

Extending the CONSORT Statement to moxibustion.

J Integr Med 2013 Jan;11(1):54-63

School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.

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http://dx.doi.org/10.3736/jintegrmed2013009DOI Listing
January 2013

Protective effects of pinostrobin on β-amyloid-induced neurotoxicity in PC12 cells.

Cell Mol Neurobiol 2012 Nov 8;32(8):1223-30. Epub 2012 May 8.

School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1007/s10571-012-9847-xDOI Listing
November 2012

Fingerprinting and simultaneous determination of alkaloids in Picrasma quassioides from different locations by high performance liquid chromatography with photodiode array detection.

J Sep Sci 2012 Sep 7;35(17):2193-202. Epub 2012 Aug 7.

New Drug Research & Development Center, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China.

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http://dx.doi.org/10.1002/jssc.201200025DOI Listing
September 2012

P75 and phosphorylated c-Jun are differentially regulated in spinal motoneurons following axotomy in rats.

Neural Regen Res 2012 Sep;7(26):2005-11

School of Chinese Medicine, Faculty of Science, the Chinese University of Hong Kong, Shatin, N.T, Hong Kong Special Administrative Region, China.

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http://dx.doi.org/10.3969/j.issn.1673-5374.2012.26.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296419PMC
September 2012

Topical herbal application as an adjuvant treatment for chronic kidney disease--a systematic review of randomized controlled clinical trials.

J Adv Nurs 2012 Aug 10;68(8):1679-91. Epub 2012 Jan 10.

School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong.

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http://doi.wiley.com/10.1111/j.1365-2648.2011.05925.x
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http://dx.doi.org/10.1111/j.1365-2648.2011.05925.xDOI Listing
August 2012

Effect of Rhizoma Polygonati on 12-O-tetradecanoylphorbol-acetate-induced ear edema in mice.

J Ethnopharmacol 2012 Aug 16;142(3):851-6. Epub 2012 Jun 16.

School of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong SAR, PR China.

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http://dx.doi.org/10.1016/j.jep.2012.06.013DOI Listing
August 2012

Bioassay-Guided Isolation of Neuroprotective Compounds from Uncaria rhynchophylla against Beta-Amyloid-Induced Neurotoxicity.

Evid Based Complement Alternat Med 2012 20;2012:802625. Epub 2012 Jun 20.

School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.

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http://dx.doi.org/10.1155/2012/802625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388340PMC
August 2012

Involvement of the mitochondrial pathway in bruceine D-induced apoptosis in Capan-2 human pancreatic adenocarcinoma cells.

Int J Mol Med 2012 Jul 23;30(1):93-9. Epub 2012 Apr 23.

School of Chinese Medicine, Faculty of Science, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, P.R. China.

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http://dx.doi.org/10.3892/ijmm.2012.980DOI Listing
July 2012

Effects of Panax notoginseng flower extract on the TGF-β/Smad signal transduction pathway in heart remodeling of human chymase transgenic mice.

Mol Med Rep 2012 Jun 2;5(6):1443-8. Epub 2012 Apr 2.

Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.

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http://dx.doi.org/10.3892/mmr.2012.856DOI Listing
June 2012

Ethyl acetate fraction of Radix rubiae inhibits cell growth and promotes terminal differentiation in cultured human keratinocytes.

J Ethnopharmacol 2012 Jun 8;142(1):241-7. Epub 2012 May 8.

School of Chinese Medicine, Faculty of Science, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.

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http://linkinghub.elsevier.com/retrieve/pii/S037887411200278
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http://dx.doi.org/10.1016/j.jep.2012.04.051DOI Listing
June 2012

Protective effect of isorhynchophylline against β-amyloid-induced neurotoxicity in PC12 cells.

Cell Mol Neurobiol 2012 Apr 1;32(3):353-60. Epub 2011 Nov 1.

School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, People's Republic of China.

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http://dx.doi.org/10.1007/s10571-011-9763-5DOI Listing
April 2012

Decreased c-Jun expression correlates with impaired spinal motoneuron regeneration in aged mice following sciatic nerve crush.

Exp Gerontol 2012 Apr 22;47(4):329-36. Epub 2012 Feb 22.

School of Chinese Medicine, Faculty of Science, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, China.

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http://dx.doi.org/10.1016/j.exger.2012.02.006DOI Listing
April 2012

Ethanolic extract of fructus Alpinia oxyphylla protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish.

Cell Mol Neurobiol 2012 Jan 9;32(1):27-40. Epub 2011 Jul 9.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Av. Padre Toma's Pereira S.J. Taipa, Macao SAR, China.

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http://dx.doi.org/10.1007/s10571-011-9731-0DOI Listing
January 2012

Uncaria rhynchophylla ameliorates cognitive deficits induced by D-galactose in mice.

Planta Med 2011 Dec 19;77(18):1977-83. Epub 2011 Aug 19.

School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N. T., Hong Kong SAR, China.

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http://dx.doi.org/10.1055/s-0031-1280125DOI Listing
December 2011

Anti-inflammatory activity of patchouli alcohol isolated from Pogostemonis Herba in animal models.

Fitoterapia 2011 Dec 19;82(8):1295-301. Epub 2011 Sep 19.

College of Chinese Medicines, Guangzhou University of Chinese Medicine, Guangzhou, PR China.

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http://dx.doi.org/10.1016/j.fitote.2011.09.003DOI Listing
December 2011

Celastrol-induced apoptosis in human HaCaT keratinocytes involves the inhibition of NF-κB activity.

Eur J Pharmacol 2011 Nov 21;670(2-3):399-408. Epub 2011 Sep 21.

School of Chinese Medicine, Faculty of Science, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.

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http://linkinghub.elsevier.com/retrieve/pii/S001429991100978
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http://dx.doi.org/10.1016/j.ejphar.2011.09.014DOI Listing
November 2011

Comparison on the anti-inflammatory effect of Cortex Phellodendri Chinensis and Cortex Phellodendri Amurensis in 12-O-tetradecanoyl-phorbol-13-acetate-induced ear edema in mice.

J Ethnopharmacol 2011 Oct 19;137(3):1425-30. Epub 2011 Aug 19.

School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, PR China.

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http://dx.doi.org/10.1016/j.jep.2011.08.014DOI Listing
October 2011

Anti-inflammatory effect of patchouli alcohol isolated from Pogostemonis Herba in LPS-stimulated RAW264.7 macrophages.

Exp Ther Med 2011 May 21;2(3):545-550. Epub 2011 Mar 21.

School of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong SAR;

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http://dx.doi.org/10.3892/etm.2011.233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440699PMC
May 2011

Sulfur-containing constituents and one 1H-pyrrole-2-carboxylic acid derivative from pineapple [Ananas comosus (L.) Merr.] fruit.

Phytochemistry 2010 Dec 16;71(17-18):2046-51. Epub 2010 Sep 16.

School of Biological Sciences, The University of Hong Kong, Hong Kong, PR China.

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http://dx.doi.org/10.1016/j.phytochem.2010.08.014DOI Listing
December 2010

Application of a combined sulphorhodamine B and melanin assay to the evaluation of Chinese medicines and their constituent compounds for hyperpigmentation treatment.

J Ethnopharmacol 2010 Oct 17;132(1):274-9. Epub 2010 Aug 17.

School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China.

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http://dx.doi.org/10.1016/j.jep.2010.08.027DOI Listing
October 2010

Tyrosinase inhibitory constituents from the roots of Morus nigra: a structure-activity relationship study.

J Agric Food Chem 2010 May;58(9):5368-73

School of Biological Sciences, The University of Hong Kong, Hong Kong, P R China.

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http://pubs.acs.org/doi/abs/10.1021/jf1003607
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May 2010

Natural taurine promotes apoptosis of human hepatic stellate cells in proteomics analysis.

World J Gastroenterol 2010 Apr;16(15):1916-23

The Affiliated Ruikang Hospital of Guangxi Traditional Chinese Medical University, Nanning 530011, Guangxi Zhuang Autonomous Region, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856835PMC
http://dx.doi.org/10.3748/wjg.v16.i15.1916DOI Listing
April 2010

Attenuation of portal hypertension by natural taurine in rats with liver cirrhosis.

World J Gastroenterol 2009 Sep;15(36):4529-37

The Affiliated Ruikang Hospital of Guangxi Traditional Chinese Medical College, Nanning 530011, Guangxi Zhuang Autonomous Region, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751997PMC
http://dx.doi.org/10.3748/wjg.15.4529DOI Listing
September 2009

Bruceine D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase.

Cancer Lett 2009 Aug 14;281(1):42-52. Epub 2009 Mar 14.

Department of Physiology, The Chinese University of Hong Kong, Shatin, NT, SAR, China.

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http://linkinghub.elsevier.com/retrieve/pii/S030438350900118
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http://dx.doi.org/10.1016/j.canlet.2009.02.017DOI Listing
August 2009

Realgar-mediated growth inhibition on HaCaT human keratinocytes is associated with induction of apoptosis.

Int J Mol Med 2009 Aug;24(2):189-96

School of Chinese Medicine, Faculty of Science, Department of Biochemistry, The Chinese University of Hong Kong, Shatin, Hong Kong, PR China.

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http://dx.doi.org/10.3892/ijmm_00000222DOI Listing
August 2009

Angiogenic effect of saponin extract from Panax notoginseng on HUVECs in vitro and zebrafish in vivo.

Phytother Res 2009 May;23(5):677-86

Institute of Chinese Medical Sciences, University of Macau, Av. Padre Tomás Pereira SJ, Taipa, Macao, China.

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http://dx.doi.org/10.1002/ptr.2705DOI Listing
May 2009

Arsenic trioxide, arsenic pentoxide, and arsenic iodide inhibit human keratinocyte proliferation through the induction of apoptosis.

J Pharmacol Exp Ther 2008 Aug 1;326(2):388-94. Epub 2008 May 1.

School of Chinese Medicine, Faculty of Science, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.

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http://dx.doi.org/10.1124/jpet.107.134080DOI Listing
August 2008

Brucea javanica fruit induces cytotoxicity and apoptosis in pancreatic adenocarcinoma cell lines.

Phytother Res 2008 Apr;22(4):477-86

School of Chinese Medicine, Faculty of Science, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, China.

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http://doi.wiley.com/10.1002/ptr.2344
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April 2008

Induction of apoptosis underlies the Radix Rubiae-mediated anti-proliferative action on human epidermal keratinocytes: implications for psoriasis treatment.

Int J Mol Med 2007 Nov;20(5):663-72

School of Chinese Medicine, Faculty of Science, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, P.R. China.

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November 2007

Evaluation of the anti-proliferative properties of selected psoriasis-treating Chinese medicines on cultured HaCaT cells.

J Ethnopharmacol 2006 Nov 5;108(1):133-41. Epub 2006 May 5.

School of Chinese Medicine, Faculty of Science, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.

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http://dx.doi.org/10.1016/j.jep.2006.04.023DOI Listing
November 2006