Publications by authors named "Zhi-Jian Wen"

3 Publications

  • Page 1 of 1

Effect of preoperative jaundice on long-term prognosis of gallbladder carcinoma with radical resection.

World J Surg Oncol 2020 Sep 5;18(1):239. Epub 2020 Sep 5.

Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Changhai Road 225, Shanghai, 200438, China.

Purposes: This study was designed to evaluate the effect of preoperative jaundice on long-term prognosis of gallbladder carcinoma (GBC) after radical resection (R0).

Methods: A total of 267 GBC patients who underwent R0 resection from January 2004 to December 2014 were enrolled, including 54 patients with preoperative jaundice and 213 patients without jaundice. The clinicopathological parameters between the two groups were compared, and the correlation between preoperative jaundice and the long-term prognosis was furtherly analyzed.

Results: Unilateral and multivariate analyses of 267 GBC patients showed that the depth of tumor invasion (pT stage), lymphatic metastasis, and hepatic invasion were independent prognostic factors. The univariate and multivariate analysis of 54 GBC patients with preoperative jaundice showed that only pT stage was an independent factor for prognosis. Furthermore, the intraoperative blood transfusion and pT stage were significant different between long-term survival (survive for more than 3 years) and those who died within 3 years (P < 0.05).

Conclusion: Preoperative jaundice was not the independent factor resulting in the poor long-term prognosis of gallbladder carcinoma after R0 resection. The pT stage was the only long-term prognostic factor in all GBC patients regardless of preoperative jaundice.
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http://dx.doi.org/10.1186/s12957-020-02015-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487893PMC
September 2020

Relationship between Prognosis and Time Interval from Cholecystectomy to Reoperation in Postoperative Incidental Gallbladder Carcinoma.

Chin Med J (Engl) 2018 Oct;131(20):2503-2505

Department of Military Health Service Management, College of Health Service, Second Military Medical University, Shanghai 200433, China.

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http://dx.doi.org/10.4103/0366-6999.243565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202608PMC
October 2018

Case-control study of the efficacy of retrogastric Roux-en-Y choledochojejunostomy.

Oncotarget 2017 Oct 8;8(46):81226-81234. Epub 2017 Mar 8.

Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.

The traditional, retrocolic/antegastric Roux-en-Y choledochojejunostomy is technically complicated, and the incidence of postoperative complications remains high. Here we report the outcome of 59 consecutively treated patients (, SG) that underwent a new choledochojejunostomy method in which the jejunal loop is passed behind the antrum pyloricum (retrogastric route). A retrospective comparison was made between this group of patients and 187 patients (, CG) that underwent conventional Roux-en-Y choledochojejunostomy (antegastric route). Baseline clinicopathological characteristics were similar in both groups, except for the BMI, which was significantly higher in the SG. The time spent on constructing the anastomosis, as well as overall postoperative complications, did not differ between groups. Compared with the CG, the incidence of postoperative delayed gastric emptying was decreased in the SG, and the time elapsed before the patients' first postoperative liquid food consumption was shorter. We ascribe these beneficial effects to the superiority of the modified, retropyloric choledochojejunostomy approach, and propose that this surgical technique is particularly suitable for obese patients, especially those with a short ascending bowel loop.
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http://dx.doi.org/10.18632/oncotarget.16006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655277PMC
October 2017