Zhi Dai

Zhi Dai

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Zhi Dai

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Metadherin-PRMT5 complex enhances the metastasis of hepatocellular carcinoma through the WNT-β-catenin signaling pathway.

Carcinogenesis 2019 Sep 9. Epub 2019 Sep 9.

Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, China.

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http://dx.doi.org/10.1093/carcin/bgz065DOI Listing
September 2019

New aporphine alkaloids with selective cytotoxicity against glioma stem cells from Thalictrum foetidum.

Chin J Nat Med 2019 Sep;17(9):698-706

Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China. Electronic address:

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http://dx.doi.org/10.1016/S1875-5364(19)30084-6DOI Listing
September 2019

Plasma hsa_circ_0027089 is a diagnostic biomarker for hepatitis B virus-related hepatocellular carcinoma.

Carcinogenesis 2019 Sep 19. Epub 2019 Sep 19.

Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, China.

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http://dx.doi.org/10.1093/carcin/bgz154DOI Listing
September 2019

Anti-inflammatory Effect of Pomelo Peel and Its Bioactive Coumarins.

J Agric Food Chem 2019 Aug 1;67(32):8810-8818. Epub 2019 Aug 1.

Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology , Yunnan University , Kunming , Yunnan 650091 , People's Republic of China.

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http://dx.doi.org/10.1021/acs.jafc.9b02511DOI Listing
August 2019

The miR-561-5p/CXCL1 Signaling Axis Regulates Pulmonary Metastasis in Hepatocellular Carcinoma Involving CXCR1 Natural Killer Cells Infiltration.

Theranostics 2019 9;9(16):4779-4794. Epub 2019 Jul 9.

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China; State Key Laboratory of Genetic Engineering, Fudan University, Shanghai, 200032, China.

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http://dx.doi.org/10.7150/thno.32543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643446PMC
July 2019

Tissue-infiltrating lymphocytes signature predicts survival in patients with early/intermediate stage hepatocellular carcinoma.

BMC Med 2019 06 5;17(1):106. Epub 2019 Jun 5.

Department of Liver Surgery, Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Liver Cancer Institute, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, People's Republic of China.

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http://dx.doi.org/10.1186/s12916-019-1341-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549297PMC
June 2019

Targeting β2 subunit of Na/K-ATPase induces glioblastoma cell apoptosis through elevation of intracellular Ca.

Am J Cancer Res 2019 1;9(6):1293-1308. Epub 2019 Jun 1.

Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province Kunming 650223, Yunnan, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610052PMC
June 2019

HNRNPAB-regulated lncRNA-ELF209 inhibits the malignancy of hepatocellular carcinoma.

Int J Cancer 2019 May 15. Epub 2019 May 15.

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/ijc.32409DOI Listing
May 2019

Folate-targeted pH-sensitive bortezomib conjugates for cancer treatment.

Chem Commun (Camb) 2019 Apr;55(29):4254-4257

Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M University, College Station, Texas 77843, USA.

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http://dx.doi.org/10.1039/c9cc01344jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543544PMC
April 2019

The Antioxidative Action of ZTP by Increasing Nrf2/ARE Signal Pathway.

Evid Based Complement Alternat Med 2019 10;2019:5421528. Epub 2019 Mar 10.

School of Life Science, Beijing Institute of Technology, Beijing 100081, China.

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https://www.hindawi.com/journals/ecam/2019/5421528/
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http://dx.doi.org/10.1155/2019/5421528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431467PMC
March 2019

Systemic inflammation score predicts survival in patients with intrahepatic cholangiocarcinoma undergoing curative resection.

J Cancer 2019 1;10(2):494-503. Epub 2019 Jan 1.

Department of General Surgery, Zhongshan Hospital (South), Fudan University, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200083, China.

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http://dx.doi.org/10.7150/jca.26890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360305PMC
January 2019

Antitumor Triterpenoid Saponin from the Fruits of Avicennia marina.

Nat Prod Bioprospect 2018 Oct 25;8(5):347-353. Epub 2018 May 25.

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.

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http://dx.doi.org/10.1007/s13659-018-0167-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109444PMC
October 2018

Comparative efficacy and safety between ablative therapies or surgery for small hepatocellular carcinoma: a network meta-analysis.

Expert Rev Gastroenterol Hepatol 2018 Sep 25;12(9):935-945. Epub 2018 Jul 25.

a Liver Cancer Institute, Zhongshan Hospital , Fudan University , Shanghai , China.

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https://www.tandfonline.com/doi/full/10.1080/17474124.2018.1
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http://dx.doi.org/10.1080/17474124.2018.1503531DOI Listing
September 2018

Novel nor-monoterpenoid indole alkaloids inhibiting glioma stem cells from fruits of Alstonia scholaris.

Phytomedicine 2018 Sep 10;48:170-178. Epub 2018 May 10.

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China; State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510120, China. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2018.04.057DOI Listing
September 2018

A new method of identifying glioblastoma subtypes and creation of corresponding animal models.

Oncogene 2018 08 17;37(35):4781-4791. Epub 2018 May 17.

Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, 650223, Kunming, Yunnan, China.

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http://dx.doi.org/10.1038/s41388-018-0305-1DOI Listing
August 2018

Antitumor aporphine alkaloids from Thalictrum wangii.

Fitoterapia 2018 Jul 24;128:204-212. Epub 2018 May 24.

Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650091, PR China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences/Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming, 650201, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2018.05.012DOI Listing
July 2018

Unprecedented sugar bridged bisindoles selective inhibiting glioma stem cells.

Bioorg Med Chem 2018 05 16;26(8):1776-1783. Epub 2018 Feb 16.

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China; Guangzhou Medical University, Guangzhou 511436, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2018.02.024DOI Listing
May 2018

A Novel Risk prediction Model for Patients with Combined Hepatocellular-Cholangiocarcinoma.

J Cancer 2018 28;9(6):1025-1032. Epub 2018 Feb 28.

Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, China.

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http://dx.doi.org/10.7150/jca.23229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868170PMC
February 2018

Surgical Treatment of Combined Hepatocellular-Cholangiocarcinoma is as Effective in Elderly Patients as it is in Younger Patients: A Propensity Score Matching Analysis.

J Cancer 2018 28;9(6):1106-1112. Epub 2018 Feb 28.

Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, China.

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http://dx.doi.org/10.7150/jca.23921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868178PMC
February 2018

The Anticancer Activities Phenolic Amides from the Stem of Lycium barbarum.

Nat Prod Bioprospect 2017 Dec 6;7(6):421-431. Epub 2017 Jun 6.

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.

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http://dx.doi.org/10.1007/s13659-017-0134-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709248PMC
December 2017

The relation between gallstone disease and cardiovascular disease.

Sci Rep 2017 11 8;7(1):15104. Epub 2017 Nov 8.

Department of endocrinology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Zhejiang, P.R. China.

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http://dx.doi.org/10.1038/s41598-017-15430-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678091PMC
November 2017

Improving Tumor Specificity and Anticancer Activity of Dasatinib by Dual-Targeted Polymeric Micelles.

ACS Appl Mater Interfaces 2017 Oct 10;9(42):36642-36654. Epub 2017 Oct 10.

Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M University Health Science Center , 1010 West Ave. B, MSC 131, Kingsville, Texas 78363, United States.

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http://dx.doi.org/10.1021/acsami.7b12233DOI Listing
October 2017

Prognostic value of systemic inflammation score in patients with hepatocellular carcinoma after hepatectomy.

Oncotarget 2017 Oct 24;8(45):79366-79375. Epub 2017 May 24.

Department of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai, P.R. China.

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http://dx.doi.org/10.18632/oncotarget.18121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668048PMC
October 2017

Coagulopathy associated with poor prognosis in intrahepatic cholangiocarcinoma patients after curative resection.

Biosci Trends 2017 Sep 7;11(4):469-474. Epub 2017 Aug 7.

Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education.

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http://dx.doi.org/10.5582/bst.2017.01080DOI Listing
September 2017

Building Stable MMP2-Responsive Multifunctional Polymeric Micelles by an All-in-One Polymer-Lipid Conjugate for Tumor-Targeted Intracellular Drug Delivery.

ACS Appl Mater Interfaces 2017 Sep 13;9(38):32520-32533. Epub 2017 Sep 13.

Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M University Health Science Center , Kingsville, Texas 78363, United States.

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http://dx.doi.org/10.1021/acsami.7b09511DOI Listing
September 2017

Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan.

Nat Prod Bioprospect 2017 Aug 15;7(4):323-327. Epub 2017 Jun 15.

State Key Laboratory of Phytochemistry and Plant Resources of West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.

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http://dx.doi.org/10.1007/s13659-017-0137-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507811PMC
August 2017

Serum exosomal miR-125b is a novel prognostic marker for hepatocellular carcinoma.

Onco Targets Ther 2017 1;10:3843-3851. Epub 2017 Aug 1.

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.2147/OTT.S140062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546809PMC
August 2017

Prostate-derived ETS factor improves prognosis and represses proliferation and invasion in hepatocellular carcinoma.

Oncotarget 2017 Aug 31;8(32):52488-52500. Epub 2017 Jan 31.

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Labolatory of Carcinogenesis and Cancer Invasion, Fudan University, Ministry of Education, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.14924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581045PMC
August 2017

Isocostunolide inhibited glioma stem cell by suppression proliferation and inducing caspase dependent apoptosis.

Bioorg Med Chem Lett 2017 07 26;27(13):2863-2867. Epub 2017 Apr 26.

Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.04.075DOI Listing
July 2017

Novel role of semaphorin 3A in the growth and progression of hepatocellular carcinoma.

Oncol Rep 2017 Jun 2;37(6):3313-3320. Epub 2017 May 2.

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.

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https://www.spandidos-publications.com/10.3892/or.2017.5616
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http://dx.doi.org/10.3892/or.2017.5616DOI Listing
June 2017

MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET-SOCS1-MMP9 signaling axis.

Cell Death Dis 2017 06 29;8(6):e2906. Epub 2017 Jun 29.

Key Laboratory of Carcinogenesis and Cancer Invasion, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Ministry of Education, Shanghai 200032, China.

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http://dx.doi.org/10.1038/cddis.2017.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520877PMC
June 2017

Cytotoxic Indole Alkaloid 3α-Acetonyltabersonine Induces Glioblastoma Apoptosis via Inhibition of DNA Damage Repair.

Toxins (Basel) 2017 04 28;9(5). Epub 2017 Apr 28.

Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, 21 Qingsong Road, Kunming 650203, China.

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http://dx.doi.org/10.3390/toxins9050150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450698PMC
April 2017

CCL24 contributes to HCC malignancy via RhoB- VEGFA-VEGFR2 angiogenesis pathway and indicates poor prognosis.

Oncotarget 2017 Jan;8(3):5135-5148

Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.14095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354897PMC
January 2017

Indole Glycosides from Aqueous Fraction of Strychnos nitida.

Nat Prod Bioprospect 2016 Dec 9;6(6):285-290. Epub 2016 Nov 9.

State Key Laboratory of Phytochemistry and Plant Resources in West China, Chinese Academy of Sciences, Kunming, 650201, China.

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http://dx.doi.org/10.1007/s13659-016-0112-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136373PMC
December 2016

Evaluation of the Transverse Displacement of the Proximal Segment After Bilateral Sagittal Split Ramus Osteotomy With Different Lingual Split Patterns and Advancement Amounts Using the Finite Element Method.

J Oral Maxillofac Surg 2016 Nov 25;74(11):2286.e1-2286.e11. Epub 2016 Jul 25.

Postgraduate Student, Department of Mechanical Engineering, Tianjin University, Tianjin, China.

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http://dx.doi.org/10.1016/j.joms.2016.07.011DOI Listing
November 2016

Overexpression of semaphorin 3A promotes tumor progression and predicts poor prognosis in hepatocellular carcinoma after curative resection.

Oncotarget 2016 Aug;7(32):51733-51746

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Fudan University, Ministry of Education, Shanghai 200032, China.

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http://dx.doi.org/10.18632/oncotarget.10104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239511PMC
August 2016

Cognitive Changes during Prolonged Stay at High Altitude and Its Correlation with C-Reactive Protein.

PLoS One 2016 5;11(1):e0146290. Epub 2016 Jan 5.

Department of Neurosurgery, Southwest Hospital, Third Military Medical University, Collaborative Innovation Center for Brain Science, Chong-Qing, 400038, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0146290PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701497PMC
June 2016

Tumor-Associated Neutrophils Recruit Macrophages and T-Regulatory Cells to Promote Progression of Hepatocellular Carcinoma and Resistance to Sorafenib.

Gastroenterology 2016 06 26;150(7):1646-1658.e17. Epub 2016 Feb 26.

Liver Surgery Department, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Fudan University, Shanghai, China; Institute of Biomedical Sciences, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.02.040DOI Listing
June 2016

Multifunctional Micellar Nanocarriers for Tumor-Targeted Delivery of Hydrophobic Drugs.

J Biomed Nanotechnol 2016 Jun;12(6):1199-210

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http://dx.doi.org/10.1166/jbn.2016.2249DOI Listing
June 2016

miR-28-5p-IL-34-macrophage feedback loop modulates hepatocellular carcinoma metastasis.

Hepatology 2016 May 7;63(5):1560-75. Epub 2016 Mar 7.

Liver Surgery Department, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University), Ministry of Education, Shanghai, China.

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http://dx.doi.org/10.1002/hep.28445DOI Listing
May 2016

MMP2-Sensitive PEG-Lipid Copolymers: A New Type of Tumor-Targeted P-Glycoprotein Inhibitor.

ACS Appl Mater Interfaces 2016 05 12;8(20):12661-73. Epub 2016 May 12.

Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M University Health Science Center , Kingsville, Texas 78363, United States.

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http://dx.doi.org/10.1021/acsami.6b03064DOI Listing
May 2016

LOXL4 is downregulated in hepatocellular carcinoma with a favorable prognosis.

Int J Clin Exp Pathol 2015 1;8(4):3892-900. Epub 2015 Apr 1.

Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466960PMC
April 2016

Caveolin-1 promotes tumor growth and metastasis via autophagy inhibition in hepatocellular carcinoma.

Clin Res Hepatol Gastroenterol 2016 Apr 20;40(2):169-78. Epub 2015 Jul 20.

Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University, 180, FengLin Road, 200032 Shanghai, China; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.clinre.2015.06.017DOI Listing
April 2016

[Study on main pharmacodynamics and underlying mechanisms of 999 Ganmaoling].

Zhongguo Zhong Yao Za Zhi 2016 Apr;41(8):1388-1396

Research Center, Huarun Three Nine Pharmaceutical Limited By Share Ltd., Shenzhen 518110, China.

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http://dx.doi.org/10.4268/cjcmm20160805DOI Listing
April 2016

The elevated preoperative neutrophil-to-lymphocyte ratio predicts poor prognosis in intrahepatic cholangiocarcinoma patients undergoing hepatectomy.

Tumour Biol 2015 Jul 12;36(7):5283-9. Epub 2015 Feb 12.

Liver Cancer Institute, Zhongshan Hospital, Fudan University, 136 Yi Xue Yuan Road, Shanghai, 200032, People's Republic of China.

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http://dx.doi.org/10.1007/s13277-015-3188-6DOI Listing
July 2015

Endoplasmic reticulum stress induces up-regulation of hepatic β-Klotho expression through ATF4 signaling pathway.

Biochem Biophys Res Commun 2015 Apr 26;459(2):300-305. Epub 2015 Feb 26.

Shanghai Key Laboratory of Diabetes Mellitus, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.02.104DOI Listing
April 2015

Negative impact of preoperative platelet-lymphocyte ratio on outcome after hepatic resection for intrahepatic cholangiocarcinoma.

Medicine (Baltimore) 2015 Apr;94(13):e574

From the Liver Cancer Institute (QC, ZD, DY, LY, ZW, YX, JF, JZ), Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education; and Institute of Biomedical Sciences (DY, JF, JZ), Fudan University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1097/MD.0000000000000574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554024PMC
April 2015

CC chemokine receptor-like 1 functions as a tumour suppressor by impairing CCR7-related chemotaxis in hepatocellular carcinoma.

J Pathol 2015 Mar 18;235(4):546-58. Epub 2014 Dec 18.

Liver Cancer Institute, Zhongshan Hospital, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Fudan University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1002/path.4450DOI Listing
March 2015

High levels of hepatitis B surface antigen are associated with poorer survival and early recurrence of hepatocellular carcinoma in patients with low hepatitis B viral loads.

Ann Surg Oncol 2015 Mar 1;22(3):843-50. Epub 2014 Oct 1.

Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

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http://dx.doi.org/10.1245/s10434-014-4043-5DOI Listing
March 2015

CXCR2/CXCL5 axis contributes to epithelial-mesenchymal transition of HCC cells through activating PI3K/Akt/GSK-3β/Snail signaling.

Cancer Lett 2015 Mar 24;358(2):124-135. Epub 2014 Nov 24.

Liver Surgery Department, Liver Cancer Institute, Zhongshan Hospital, Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University), Ministry of Education, Fudan University, Shanghai 200032, China; Institute of Biomedical Sciences, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.11.044DOI Listing
March 2015

Macrophage-secreted IL-8 induces epithelial-mesenchymal transition in hepatocellular carcinoma cells by activating the JAK2/STAT3/Snail pathway.

Int J Oncol 2015 Feb 18;46(2):587-96. Epub 2014 Nov 18.

Liver Cancer Institute, Zhongshan Hospital, Key Laboratory of Carcinogenesis and Cancer Invasion, Fudan University, Ministry of Education, Shanghai 200032, P.R. China.

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http://dx.doi.org/10.3892/ijo.2014.2761DOI Listing
February 2015

PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma.

Oncotarget 2015 Jan;6(2):846-61

Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359260PMC
http://dx.doi.org/10.18632/oncotarget.2749DOI Listing
January 2015

Addition of poly (propylene glycol) to multiblock copolymer to optimize siRNA delivery.

Bioengineered 2014 Jan-Feb;5(1):30-7. Epub 2013 Dec 18.

Center of Excellence for Infectious Diseases; Department of Biomedical Sciences; Paul L Foster School of Medicine; Texas Tech University Health Sciences Center; El Paso, TX USA.

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http://dx.doi.org/10.4161/bioe.27339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008463PMC
December 2014

Capn4 contributes to tumour growth and metastasis of hepatocellular carcinoma by activation of the FAK-Src signalling pathways.

J Pathol 2014 Nov 18;234(3):316-28. Epub 2014 Aug 18.

Liver Cancer Institute and Zhongshan Hospital, Key Laboratory of Carcinogenesis and Cancer Invasion, Fudan University, Ministry of Education, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1002/path.4395DOI Listing
November 2014

Fibroblast growth factor 21 is regulated by the IRE1α-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis.

J Biol Chem 2014 Oct 28;289(43):29751-65. Epub 2014 Aug 28.

From the Shanghai Key Laboratory of Diabetes Mellitus, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, and Shanghai Key Clinical Center for Metabolic Disease, Shanghai JiaoTong University Affiliated Sixth People's Hospital, Shanghai 200233,

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http://dx.doi.org/10.1074/jbc.M114.565960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207989PMC
October 2014

Human miR-1228 as a stable endogenous control for the quantification of circulating microRNAs in cancer patients.

Int J Cancer 2014 Sep 10;135(5):1187-94. Epub 2014 Mar 10.

Liver Cancer Institute Zhongshan Hospital, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Fudan University, Shanghai, China.

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http://doi.wiley.com/10.1002/ijc.28757
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http://dx.doi.org/10.1002/ijc.28757DOI Listing
September 2014

Tacrolimus promotes hepatocellular carcinoma and enhances CXCR4/SDF‑1α expression in vivo.

Mol Med Rep 2014 Aug 5;10(2):585-92. Epub 2014 Jun 5.

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.

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http://dx.doi.org/10.3892/mmr.2014.2302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094770PMC
August 2014

Expression of hemopexin in acute rejection of rat liver allograft identified by serum proteomic analysis.

Shock 2014 Jul;42(1):65-74

*Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China; †Departments of General and Visceral Surgery, and ‡Gastroenterology and Endocrinology, University Medical Center Goettingen, Goettingen, Germany; and §Department of Surgery, Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou; and ∥Shanghai Key Laboratory of Organ Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1097/SHK.0000000000000171DOI Listing
July 2014

Synthesis and characterization of electron donor-acceptor platinum(II) complexes composed of N,N-diphenylpyridineamine and triphenylamine ligands.

Inorg Chem 2014 Jul 27;53(14):7188-96. Epub 2014 Jun 27.

Department of Chemistry, University of Texas at El Paso , 500 W. University Avenue, El Paso, Texas 79968, United States.

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http://dx.doi.org/10.1021/ic500290mDOI Listing
July 2014

MiR-302c inhibits tumor growth of hepatocellular carcinoma by suppressing the endothelial-mesenchymal transition of endothelial cells.

Sci Rep 2014 Jul 16;4:5524. Epub 2014 Jul 16.

1] Liver Cancer Institute, Zhong Shan Hospital, Fudan University, Shanghai, 200032 China; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University), Ministry of Education [2] Shanghai Key Laboratory of Organ Transplantation, Zhong Shan Hospital, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1038/srep05524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100019PMC
July 2014

Clinical significance of the ubiquitin ligase UBE3C in hepatocellular carcinoma revealed by exome sequencing.

Hepatology 2014 Jun 2;59(6):2216-27. Epub 2014 May 2.

Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, P.R. China.

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http://doi.wiley.com/10.1002/hep.27012
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June 2014

Activating mutations in PTPN3 promote cholangiocarcinoma cell proliferation and migration and are associated with tumor recurrence in patients.

Gastroenterology 2014 May 4;146(5):1397-407. Epub 2014 Feb 4.

Liver Cancer Institute, Zhongshan Hospital, and Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Fudan University, Shanghai, China; Cancer Center, Institute of Biomedical Sciences, Fudan University, Shanghai, China. Electronic address:

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May 2014

HNRNPAB induces epithelial-mesenchymal transition and promotes metastasis of hepatocellular carcinoma by transcriptionally activating SNAIL.

Cancer Res 2014 May 17;74(10):2750-62. Epub 2014 Mar 17.

Authors' Affiliations: Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education; and Institute of Biomedical Sciences, Fudan University, Shanghai, ChinaAuthors' Affiliations: Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education; and Institute of Biomedical Sciences, Fudan University, Shanghai, ChinaAuthors' Affiliations: Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education; and Institute of Biomedical Sciences, Fudan University, Shanghai, China

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2509DOI Listing
May 2014

High expression of 5-hydroxymethylcytosine and isocitrate dehydrogenase 2 is associated with favorable prognosis after curative resection of hepatocellular carcinoma.

J Exp Clin Cancer Res 2014 Apr 10;33:32. Epub 2014 Apr 10.

Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai 200032, China.

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http://dx.doi.org/10.1186/1756-9966-33-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081660PMC
April 2014

CXCL5 contributes to tumor metastasis and recurrence of intrahepatic cholangiocarcinoma by recruiting infiltrative intratumoral neutrophils.

Carcinogenesis 2014 Mar 30;35(3):597-605. Epub 2013 Nov 30.

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai 200032, China and.

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http://dx.doi.org/10.1093/carcin/bgt397DOI Listing
March 2014

Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells.

Autophagy 2013 Dec 1;9(12):2056-68. Epub 2013 Oct 1.

Department of Liver Surgery; Liver Cancer Institute; Zhongshan Hospital; Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education; Shanghai, China.

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http://dx.doi.org/10.4161/auto.26398DOI Listing
December 2013

Margin-infiltrating CD20(+) B cells display an atypical memory phenotype and correlate with favorable prognosis in hepatocellular carcinoma.

Clin Cancer Res 2013 Nov 20;19(21):5994-6005. Epub 2013 Sep 20.

Authors' Affiliations: Liver Cancer Institute and Biomedical Research Center, Zhongshan Hospital; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, and Institute of Biomedical Sciences, Fudan University, Shanghai, PR China.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-3497DOI Listing
November 2013

MiR-146a enhances angiogenic activity of endothelial cells in hepatocellular carcinoma by promoting PDGFRA expression.

Carcinogenesis 2013 Sep 13;34(9):2071-9. Epub 2013 May 13.

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1093/carcin/bgt160DOI Listing
September 2013

Enantiomeric separation of racemic 4-aryl-1,4-dihydropyridines and 4-aryl-1,2,3,4-tetrahydropyrimidines on a chiral tetraproline stationary phase.

Chirality 2013 Apr 1;25(4):238-42. Epub 2013 Mar 1.

Department of Chemistry, Box 9573, Mississippi State University, Mississippi State, MS 39762, USA.

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http://dx.doi.org/10.1002/chir.22135DOI Listing
April 2013

Plasma microRNA, a potential biomarker for acute rejection after liver transplantation.

Transplantation 2013 Apr;95(8):991-9

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University), the Chinese Ministry of Education, and Shanghai Key Laboratory for Organ Transplantation, Shanghai, PR China.

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http://dx.doi.org/10.1097/TP.0b013e31828618d8DOI Listing
April 2013

The ion implantation-induced properties of one-dimensional nanomaterials.

Nanoscale Res Lett 2013 Apr 17;8(1):175. Epub 2013 Apr 17.

Department of Physics and Key Laboratory of Artificial Micro- and Nano-structures of Ministry of Education, Wuhan University, Wuhan, 430072, People's Republic of China.

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http://dx.doi.org/10.1186/1556-276X-8-175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668221PMC
April 2013

Overexpression of HnRNP A1 promotes tumor invasion through regulating CD44v6 and indicates poor prognosis for hepatocellular carcinoma.

Int J Cancer 2013 Mar 7;132(5):1080-9. Epub 2012 Aug 7.

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/ijc.27742DOI Listing
March 2013

Biomarkers for hepatocellular carcinoma: progression in early diagnosis, prognosis, and personalized therapy.

Biomark Res 2013 Feb 5;1(1):10. Epub 2013 Feb 5.

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

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http://dx.doi.org/10.1186/2050-7771-1-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177612PMC
February 2013

T2* MRI of minimal hepatic encephalopathy and cognitive correlates in vivo.

J Magn Reson Imaging 2013 Jan 25;37(1):179-86. Epub 2012 Sep 25.

Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/jmri.23811DOI Listing
January 2013

Overexpression of CXCL5 mediates neutrophil infiltration and indicates poor prognosis for hepatocellular carcinoma.

Hepatology 2012 Dec;56(6):2242-54

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1002/hep.25907DOI Listing
December 2012

Enantiomeric recognition of racemic 4-aryl-1,4-dihydropyridine derivatives via chiralpak AD-H stationary phases.

Chirality 2012 Oct 10;24(10):854-9. Epub 2012 Jul 10.

Department of Chemistry, Mississippi State University, Mississippi, USA.

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http://dx.doi.org/10.1002/chir.22083DOI Listing
October 2012

Activation of PI3K/AKT and MAPK pathway through a PDGFRβ-dependent feedback loop is involved in rapamycin resistance in hepatocellular carcinoma.

PLoS One 2012 9;7(3):e33379. Epub 2012 Mar 9.

Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302853PMC
August 2012

Solution-phase synthesis and evaluation of tetraproline chiral stationary phases.

Chirality 2012 Apr 17;24(4):329-38. Epub 2012 Feb 17.

Department of Chemistry, Mississippi State University, Starkville, Mississippi, USA.

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http://dx.doi.org/10.1002/chir.22001DOI Listing
April 2012

Genetic variations in plasma circulating DNA of HBV-related hepatocellular carcinoma patients predict recurrence after liver transplantation.

PLoS One 2011 5;6(10):e26003. Epub 2011 Oct 5.

Liver Cancer Institute, Zhong Shan Hospital, Fudan University, Key Laboratory for Carcinogenesis and Cancer Invasion, the Chinese Ministry of Education, Shanghai Key Laboratory for Organ Transplantation, Shanghai, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0026003PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187841PMC
February 2012

Prognostic indicators for tumor recurrence after liver transplantation in hepatocellular carcinoma and related molecular targeted therapy.

Oncology 2011 22;81 Suppl 1:116-22. Epub 2011 Dec 22.

Liver Cancer Institute, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1159/000333273DOI Listing
February 2012

Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma.

J Clin Oncol 2011 Dec 21;29(36):4781-8. Epub 2011 Nov 21.

Liver Cancer Institute, Zhongshan Hospital, Fudan University, People's Republic of China.

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http://dx.doi.org/10.1200/JCO.2011.38.2697DOI Listing
December 2011

Validity of plasma macrophage migration inhibitory factor for diagnosis and prognosis of hepatocellular carcinoma.

Int J Cancer 2011 Nov 20;129(10):2463-72. Epub 2011 Apr 20.

Liver Cancer Institute, Fudan University and Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University), Ministry of Education, Shanghai, China.

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http://doi.wiley.com/10.1002/ijc.25918
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November 2011

Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis.

Autophagy 2011 Oct 1;7(10):1159-72. Epub 2011 Oct 1.

Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.4161/auto.7.10.16818DOI Listing
October 2011

An immune function assay predicts post-transplant recurrence in patients with hepatocellular carcinoma.

J Cancer Res Clin Oncol 2011 Oct 2;137(10):1445-53. Epub 2011 Aug 2.

Department of Liver Surgery, Liver Cancer Institute, Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai, 200032, China.

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http://link.springer.com/content/pdf/10.1007/s00432-011-1014
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http://link.springer.com/10.1007/s00432-011-1014-0
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October 2011

Autophagy activation in hepatocellular carcinoma contributes to the tolerance of oxaliplatin via reactive oxygen species modulation.

Clin Cancer Res 2011 Oct 8;17(19):6229-38. Epub 2011 Aug 8.

Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Shanghai, China.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-0816DOI Listing
October 2011

An investigation of the effect of sorafenib on tumour growth and recurrence after liver cancer resection in nude mice independent of phosphorylated extracellular signal-regulated kinase levels.

Expert Opin Investig Drugs 2011 Aug 14;20(8):1039-45. Epub 2011 Jun 14.

Fudan University, Liver Cancer Institute and Zhongshan Hospital, Shanghai, P.R. China.

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http://dx.doi.org/10.1517/13543784.2011.588598DOI Listing
August 2011

Steric effects on the enantiodiscrimination of diproline chiral stationary phases in the resolution of racemic compounds.

J Chromatogr A 2011 Aug 21;1218(32):5498-503. Epub 2011 Jun 21.

Department of Chemistry, Box 9573, Mississippi State University, MS 39762, USA.

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http://dx.doi.org/10.1016/j.chroma.2011.06.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154017PMC
August 2011

[Cellular signaling pathways involved in hepatocellular carcinoma occurrence and progression].

Zhonghua Gan Zang Bing Za Zhi 2010 Dec;18(12):955-7

Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.3760/cma.j.issn.1007-3418.2010.12.022DOI Listing
December 2010