Zhenyu Zhong

Zhenyu Zhong

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Zhenyu Zhong

Publications by authors named "Zhenyu Zhong"

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Membrane-bound and soluble porcine CD83 functions antithetically in T cell activation and dendritic cell differentiation in vitro.

Dev Comp Immunol 2019 10 20;99:103398. Epub 2019 May 20.

Laboratory of Molecular Virology and Immunology, College of Animal Science and Technology/College of Veterinary Medicine, Hebei Agricultural University, Baoding, Hebei, 071000, China; Hebei Engineering and Technology Research Center of Veterinary Biotechnology, Baoding, Hebei, 071000, China. Electronic address:

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http://dx.doi.org/10.1016/j.dci.2019.103398DOI Listing
October 2019

Comparison of Clinical Features and Visual Outcome between Sympathetic Ophthalmia and Vogt-Koyanagi-Harada Disease in Chinese Patients.

Ophthalmology 2019 Sep 6;126(9):1297-1305. Epub 2019 Apr 6.

University Eye Clinic, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.ophtha.2019.03.049DOI Listing
September 2019

Lychee Fruit Detection Based on Monocular Machine Vision in Orchard Environment.

Sensors (Basel) 2019 Sep 21;19(19). Epub 2019 Sep 21.

Academy of Contemporary Agricultural Engineering Innovations, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.

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http://dx.doi.org/10.3390/s19194091DOI Listing
September 2019

Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon regulatory factor 1 (IRF1) and removing damaged mitochondria.

J Biol Chem 2019 Aug 24;294(33):12359-12369. Epub 2019 Jun 24.

Division of Digestive and Liver Diseases, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048

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http://dx.doi.org/10.1074/jbc.RA119.007409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699832PMC
August 2019

Assessment of External Properties for Identifying Banana Fruit Maturity Stages Using Optical Imaging Techniques.

Sensors (Basel) 2019 Jul 1;19(13). Epub 2019 Jul 1.

Academy of Contemporary Agricultural Engineering Innovations, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.

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http://dx.doi.org/10.3390/s19132910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651252PMC
July 2019

Association of toll-like receptor 10 polymorphisms with paediatric idiopathic uveitis in Han Chinese.

Br J Ophthalmol 2019 Jul 4. Epub 2019 Jul 4.

The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology and Chongqing Eye Institute, Chongqing, China

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http://dx.doi.org/10.1136/bjophthalmol-2019-314483DOI Listing
July 2019

A multiple modulation synthesis method with high spatial resolution for noninvasive neurostimulation.

PLoS One 2019 20;14(6):e0218293. Epub 2019 Jun 20.

School of Electronic and Information Engineering, South China University of Technology, Guangzhou, Guangdong, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218293PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586313PMC
June 2019

Porcine Parvovirus Infection Causes Pig Placenta Tissue Damage Involving Nonstructural Protein 1 (NS1)-Induced Intrinsic ROS/Mitochondria-Mediated Apoptosis.

Viruses 2019 Apr 25;11(4). Epub 2019 Apr 25.

Laboratory of Molecular Virology and Immunology, College of Animal Science and Technology/College of Veterinary Medicine, Hebei Agricultural University, Hebei Engineering and Technology Research Center of Veterinary Biotechnology, Baoding 071000, China.

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http://dx.doi.org/10.3390/v11040389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520726PMC
April 2019

Porcine CD83 is a glycosylated dimeric protein existing naturally in membrane-bound and soluble forms.

Dev Comp Immunol 2019 01 5;90:60-69. Epub 2018 Sep 5.

Laboratory of Molecular Virology and Immunology, College of Animal Science and Technology/College of Veterinary Medicine, Agricultural University of Hebei, Baoding, Hebei, 071000, China; Hebei Engineering and Technology Research Center of Veterinary Biotechnology, Baoding, Hebei, 071000, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0145305X183038
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http://dx.doi.org/10.1016/j.dci.2018.09.002DOI Listing
January 2019

Author Correction: Inflammation-induced IgA cells dismantle anti-liver cancer immunity.

Nature 2018 09;561(7721):E1

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, California, 92093, USA.

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http://dx.doi.org/10.1038/s41586-018-0304-yDOI Listing
September 2018

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.

Nature 2018 08 25;560(7717):198-203. Epub 2018 Jul 25.

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, CA, USA.

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http://www.nature.com/articles/s41586-018-0372-z
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http://dx.doi.org/10.1038/s41586-018-0372-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329306PMC
August 2018

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity.

Nature 2017 11 8;551(7680):340-345. Epub 2017 Nov 8.

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1038/nature24302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884449PMC
November 2017

lncRNA H19 regulates epithelial-mesenchymal transition and metastasis of bladder cancer by miR-29b-3p as competing endogenous RNA.

Biochim Biophys Acta Mol Cell Res 2017 Oct 2;1864(10):1887-1899. Epub 2017 Aug 2.

Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2017.08.001DOI Listing
October 2017

Circular RNA MYLK as a competing endogenous RNA promotes bladder cancer progression through modulating VEGFA/VEGFR2 signaling pathway.

Cancer Lett 2017 09 4;403:305-317. Epub 2017 Jul 4.

Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing, 400016, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.06.027DOI Listing
September 2017

Fabrication, characterization, and in vitro study of zinc substituted hydroxyapatite/silk fibroin composite coatings on titanium for biomedical applications.

Authors:
Zhenyu Zhong Jun Ma

J Biomater Appl 2017 09 26;32(3):399-409. Epub 2017 Jul 26.

Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.

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http://dx.doi.org/10.1177/0885328217723501DOI Listing
September 2017

Limiting inflammation-the negative regulation of NF-κB and the NLRP3 inflammasome.

Nat Immunol 2017 Jul;18(8):861-869

Unit of Molecular Signal Transduction in Inflammation, Center for Inflammation Research, VIB, Ghent, Belgium.

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http://dx.doi.org/10.1038/ni.3772DOI Listing
July 2017

Papilloma-pseudovirus eradicates intestinal tumours and triples the lifespan of Apc mice.

Nat Commun 2017 04 11;8:15004. Epub 2017 Apr 11.

Department of Microbiology and Immunology, Stritch School of Medicine, Health Sciences Division, Loyola University Chicago, Maywood, Illinois 60153, USA.

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http://dx.doi.org/10.1038/ncomms15004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394268PMC
April 2017

Autophagy, NLRP3 inflammasome and auto-inflammatory/immune diseases.

Clin Exp Rheumatol 2016 Jul-Aug;34(4 Suppl 98):12-6. Epub 2016 Jul 21.

Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology; and Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.

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December 2016

Cancel Yulin's annual dog meat festival.

Science 2016 09;353(6304):1107

Beijing Milu Ecological Research Centre, Beijing, 100076, China.

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http://dx.doi.org/10.1126/science.aah4388DOI Listing
September 2016

Screening differential circular RNA expression profiles reveals the regulatory role of circTCF25-miR-103a-3p/miR-107-CDK6 pathway in bladder carcinoma.

Sci Rep 2016 08 3;6:30919. Epub 2016 Aug 3.

Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China.

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http://dx.doi.org/10.1038/srep30919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971518PMC
August 2016

Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.

J Exp Clin Cancer Res 2016 08 30;35(1):130. Epub 2016 Aug 30.

Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing, 400016, China.

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http://dx.doi.org/10.1186/s13046-016-0408-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006283PMC
August 2016

Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment.

Cell 2016 Jul;166(2):288-298

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA; Department of Pathology, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.05.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947210PMC
July 2016

Motor nerve conduction velocity is affected in segmental vitiligo lesional limbs.

Int J Dermatol 2016 Jun 24;55(6):700-5. Epub 2016 Feb 24.

Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1111/ijd.13171DOI Listing
June 2016

p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells.

Cancer Cell 2016 06 19;29(6):935-948. Epub 2016 May 19.

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA; Department of Pathology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907799PMC
June 2016

Biomimetic synthesis of hybrid hydroxyapatite nanoparticles using nanogel template for controlled release of bovine serum albumin.

Mater Sci Eng C Mater Biol Appl 2016 May 4;62:377-83. Epub 2016 Feb 4.

Advanced Biomaterials and Tissue Engineering Center, Huazhong University of Science and Technology, Wuhan 430074, PR China; Department of Biomedical Engineering, School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.msec.2016.01.088DOI Listing
May 2016

NLRP3 inflammasome activation contributes to Listeria monocytogenes-induced animal pregnancy failure.

BMC Vet Res 2016 Feb 24;12:36. Epub 2016 Feb 24.

Laboratory of Molecular Virology and Immunology, College of Veterinary Medicine, Agricultural University of Hebei; Hebei Engineering and Technology Research Center of Veterinary Biotechnology, Baoding, 071000, China.

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http://dx.doi.org/10.1186/s12917-016-0655-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765044PMC
February 2016

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.

Cell 2016 Feb;164(5):896-910

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA; Department of Pathology, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.12.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769378PMC
February 2016

Mutual enhancement of IL-2 and IL-7 on DNA vaccine immunogenicity mainly involves regulations on their receptor expression and receptor-expressing lymphocyte generation.

Vaccine 2015 Jul 9;33(30):3480-7. Epub 2015 Jun 9.

Laboratory of Molecular Virology and Immunology, College of Veterinary Medicine, Agricultural University of Hebei, Hebei Engineering and Technology Research Center of Veterinary Biotechnology, Baoding 071000, China. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.05.068DOI Listing
July 2015

Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy.

Nature 2015 May 29;521(7550):94-8. Epub 2015 Apr 29.

1] Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, San Diego, California 92093, USA [2] Department of Pathology, School of Medicine, University of California San Diego, 9500 Gilman Drive, San Diego, California 92093, USA.

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http://dx.doi.org/10.1038/nature14395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501632PMC
May 2015

Cellulose acetate/hydroxyapatite/chitosan coatings for improved corrosion resistance and bioactivity.

Mater Sci Eng C Mater Biol Appl 2015 Apr 8;49:251-255. Epub 2015 Jan 8.

Advanced Biomaterials and Tissue Engineering Center, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China; Department of Biomedical Engineering, School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.msec.2015.01.020DOI Listing
April 2015

Soluble CD83 inhibits human monocyte differentiation into dendritic cells in vitro.

Cell Immunol 2014 Nov-Dec;292(1-2):25-31. Epub 2014 Sep 6.

Department of Biotechnology, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, China. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2014.08.003DOI Listing
February 2015

Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis.

Immunity 2014 Dec 25;41(6):1052-63. Epub 2014 Nov 25.

Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0723, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613140043
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http://dx.doi.org/10.1016/j.immuni.2014.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272447PMC
December 2014

ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development.

Cancer Cell 2014 Sep 14;26(3):331-343. Epub 2014 Aug 14.

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California, San Diego, 9500 Gilman Drive, San Diego, CA 92093, USA; Department of Pathology, School of Medicine, University of California, San Diego, 9500 Gilman Drive, San Diego, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165611PMC
September 2014

Soluble form of canine transferrin receptor inhibits canine parvovirus infection in vitro and in vivo.

Biomed Res Int 2013 8;2013:172479. Epub 2013 Sep 8.

Laboratory of Molecular Virology and Immunology, College of Veterinary Medicine, Agricultural University of Hebei, Baodiing 071001, China ; Hebei Engineering and Technology Research Center of Veterinary Biological Products, North China Research Center of Animal Epidemic Pathogen Biology, China Agriculture Ministry, Baoding 071001, China.

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http://dx.doi.org/10.1155/2013/172479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780538PMC
June 2014

Molecular mechanism for the effects of E. coli heat-labile enterotoxin on mouse embryo survival.

Reprod Toxicol 2014 Jun 17;45:31-8. Epub 2014 Jan 17.

Laboratory of Molecular Virology and Immunology, College of Veterinary Medicine, Agricultural University of Hebei, Baoding 071001, China; Hebei Engineering and Technology Research Center of Veterinary Biotechnology , Baoding 071001, China. Electronic address:

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http://dx.doi.org/10.1016/j.reprotox.2014.01.005DOI Listing
June 2014

Novel fate-tracing strategies show that hepatic stellate cells mediate fibrosis in vivo.

Gastroenterology 2014 Jun 21;146(7):1823-5. Epub 2014 Apr 21.

Division of Gastroenterology, Department of Medicine, University of California San Diego, La Jolla, California.

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http://dx.doi.org/10.1053/j.gastro.2014.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743044PMC
June 2014

Transient receptor potential melastatin 2: a novel target for treatment of gout.

Expert Opin Ther Targets 2013 Nov 4;17(11):1243-7. Epub 2013 Sep 4.

Loyola University Chicago, Stritch School of Medicine, Department of Microbiology and Immunology , 2610 South First Ave, Maywood, IL 60153 , USA

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http://dx.doi.org/10.1517/14728222.2013.835399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106263PMC
November 2013

Bovine papillomavirus-like particles presenting conserved epitopes from membrane-proximal external region of HIV-1 gp41 induced mucosal and systemic antibodies.

Vaccine 2013 Nov 19;31(46):5422-9. Epub 2013 Sep 19.

Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, United States.

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http://dx.doi.org/10.1016/j.vaccine.2013.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881962PMC
November 2013

TRPM2 links oxidative stress to NLRP3 inflammasome activation.

Nat Commun 2013 ;4:1611

Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 60153, USA.

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http://dx.doi.org/10.1038/ncomms2608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605705PMC
October 2013

Porcine reproductive and respiratory syndrome virus activates inflammasomes of porcine alveolar macrophages via its small envelope protein E.

Virology 2013 Aug 8;442(2):156-62. Epub 2013 May 8.

Laboratory of Molecular Virology and Immunology, College of Veterinary Medicine, Agricultural University of Hebei, Hebei Engineering and Technology Research Center of Veterinary Biological Products, Baoding, China.

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http://dx.doi.org/10.1016/j.virol.2013.04.007DOI Listing
August 2013

TRPM2 links oxidative stress to the NLRP3 inflammasome activation (P1268).

J Immunol 2013 ;190

Department of Microbiology and Immunology, Loyola University Chicago, Maywood, IL.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160441PMC
January 2013

Increased CSF-BACE1 activity associated with decreased hippocampus volume in Alzheimer's disease.

J Alzheimers Dis 2011 ;25(2):373-81

Discipline of Psychiatry, School of Medicine & Trinity College Institute of Neuroscience, Laboratory of Neuroimaging & Biomarker Research, Trinity College, University of Dublin, The Adelaide and Meath Hospital Incorporating The National Children's Hospital, Tallaght, Ireland.

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http://dx.doi.org/10.3233/JAD-2011-091153DOI Listing
November 2011

Effect of cryopreservation on IL-4, IFNgamma and IL-6 production of porcine peripheral blood lymphocytes.

Cryobiology 2009 Dec 18;59(3):322-6. Epub 2009 Sep 18.

Dept. of Biotechnology, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, Hebei 066004, China.

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http://dx.doi.org/10.1016/j.cryobiol.2009.09.004DOI Listing
December 2009

Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients.

Mol Neurodegener 2009 Jul 15;4:30. Epub 2009 Jul 15.

Haldeman Laboratory of Molecular and Cellular Neurobiology, Sun Health Research Institute, Sun City, AZ USA.

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http://dx.doi.org/10.1186/1750-1326-4-30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722623PMC
July 2009

Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease.

Brain 2008 May 11;131(Pt 5):1252-8. Epub 2008 Mar 11.

Department of Psychiatry, Alzheimer Memorial Center, Ludwig-Maximilian University, Munich, Germany.

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http://dx.doi.org/10.1093/brain/awn034DOI Listing
May 2008

Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment.

Arch Gen Psychiatry 2007 Jun;64(6):718-26

Haldeman Laboratory of Molecular and Cellular Neurobiology, Sun Health Research Institute, Sun City, AZ 85351, USA.

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http://dx.doi.org/10.1001/archpsyc.64.6.718DOI Listing
June 2007

Distinct destructive signal pathways of neuronal death in Alzheimer's disease.

Trends Mol Med 2006 Dec 19;12(12):574-9. Epub 2006 Oct 19.

Haldeman Laboratory of Molecular and Cellular Neurobiology, Sun Health Research Institute 3501, West Santa Fe Drive, Sun City, AZ 85351, USA.

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http://dx.doi.org/10.1016/j.molmed.2006.10.002DOI Listing
December 2006

ACTR/AIB1/SRC-3 and androgen receptor control prostate cancer cell proliferation and tumor growth through direct control of cell cycle genes.

Prostate 2006 Oct;66(14):1474-86

UC Davis Cancer Center/Basic Sciences, Department of Biochemistry & Molecular Medicine, University of California at Davis, School of Medicine, Sacramento, California, USA.

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http://dx.doi.org/10.1002/pros.20477DOI Listing
October 2006

Brain estrogen deficiency accelerates Abeta plaque formation in an Alzheimer's disease animal model.

Proc Natl Acad Sci U S A 2005 Dec 19;102(52):19198-203. Epub 2005 Dec 19.

L. J. Roberts Center for Alzheimer's Research and Haldeman Laboratory for Molecular and Cellular Neurobiology, Sun Health Research Institute, Sun City, AZ 85351, USA.

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http://dx.doi.org/10.1073/pnas.0505203102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1323154PMC
December 2005

Screening of the antigen epitopes of basic fibroblast growth factor by phage display.

J Biochem Mol Biol 2005 May;38(3):290-3

Lab of Molecular Immunology and Antibody Engineering in Life Science and Technological College, Jinan University, Guangzhou, 510632, China.

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May 2005