Publications by authors named "Zhengping Zhuang"

100Publications

A Novel In Vitro Device to Deliver Induced Electromagnetic Fields to Cell and Tissue Cultures.

Biophys J 2020 Dec 13;119(12):2378-2390. Epub 2020 Nov 13.

Section on Quantitative Imaging and Tissue Sciences Eunice Kennedy Shriver National Institutes of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland. Electronic address:

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December 2020

C-Terminal, but Not Intact, FGF23 and EPO Are Strongly Correlatively Elevated in Patients With Gain-of-Function Mutations in HIF2A: Clinical Evidence for EPO Regulating FGF23.

J Bone Miner Res 2020 Oct 13. Epub 2020 Oct 13.

Skeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.

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October 2020

TP5, a Peptide Inhibitor of Aberrant and Hyperactive CDK5/p25: A Novel Therapeutic Approach against Glioblastoma.

Cancers (Basel) 2020 Jul 17;12(7). Epub 2020 Jul 17.

Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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July 2020

Inhibition of protein phosphatase-2A with LB-100 enhances antitumor immunity against glioblastoma.

J Neurooncol 2020 Jun 27;148(2):231-244. Epub 2020 Apr 27.

Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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June 2020

Neuraxial dysraphism in associated syndrome due to improper mesenchymal transition.

Neurol Genet 2020 Jun 1;6(3):e414. Epub 2020 Apr 1.

National Institutes of Health (J.S.R., A.J.C., H.W., Z.Z.), National Cancer Institute Neuro-Oncology Branch; National Institutes of Health (D.P.A., J.D.H.), National Institute of Neurological Disorders and Stroke, Surgical Neurology Branch; National Institutes of Health (Y.P., A.J., K.P.), Eunice Kennedy Shriver National Institute of Child Health and Human Development, Section on Medical Neuroendocrinology; Georgetown Hospital (M.A.N.), Internal Medicine and Pediatrics, Washington DC; National Institutes of Health (J.P.M., D.R.D.), National Institute of Neurological Disorders and Stroke, Mouse Imaging Facility, Bethesda, MD; George Washington University (J.G.S.), Radiology, Washington DC; National Library of Medicine (J.G.S.), MedPix®; National Institutes of Health (M.M.M.), Center for Cancer Research, National Cancer Institute, Laboratory of Pathology; and National Institutes of Health (R.H.K., B.A.K.), National Heart Lung and Blood Institute, Translational Vascular Medicine Branch, Bethesda, MD.

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June 2020

A novel germline gain-of-function HIF2A mutation in hepatocellular carcinoma with polycythemia.

Aging (Albany NY) 2020 04 1;12(7):5781-5791. Epub 2020 Apr 1.

State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou City, China.

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April 2020

Targeting PP2A inhibits the growth of triple-negative breast cancer cells.

Cell Cycle 2020 03 3;19(5):592-600. Epub 2020 Feb 3.

Department of Oncology and Pathology, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.

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March 2020

Inhibition of PP2A with LB-100 Enhances Efficacy of CAR-T Cell Therapy Against Glioblastoma.

Cancers (Basel) 2020 Jan 6;12(1). Epub 2020 Jan 6.

Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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January 2020

Clinical manifestations of Pacak-Zhuang syndrome in a male pediatric patient.

Pediatr Blood Cancer 2020 04 25;67(4):e28096. Epub 2019 Dec 25.

Department of Pathology and Laboratory Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.

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April 2020

Coley's immunotherapy revived: Innate immunity as a link in priming cancer cells for an attack by adaptive immunity.

Semin Oncol 2019 Aug - Oct;46(4-5):385-392. Epub 2019 Nov 6.

Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, MD 20814, USA. Electronic address:

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January 2020

Blocking lncRNA MALAT1/miR-199a/ZHX1 Axis Inhibits Glioblastoma Proliferation and Progression.

Mol Ther Nucleic Acids 2019 Dec 17;18:388-399. Epub 2019 Sep 17.

Department of Neurosurgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No. 160, Pujian Road, District Pudong, Shanghai 200127, China. Electronic address:

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December 2019

DAPT, a γ-Secretase Inhibitor, Suppresses Tumorigenesis, and Progression of Growth Hormone-Producing Adenomas by Targeting Notch Signaling.

Front Oncol 2019 27;9:809. Epub 2019 Aug 27.

Key Laboratory of Central Nervous System Injury Research, Center of Brain Tumor of Beijing Institute for Brain Disorders, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.

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August 2019

Chiari Malformation Type 1 in -Associated Syndrome.

Int J Mol Sci 2019 Jun 10;20(11). Epub 2019 Jun 10.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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June 2019

EGFR signaling confers resistance to BET inhibition in hepatocellular carcinoma through stabilizing oncogenic MYC.

J Exp Clin Cancer Res 2019 Feb 15;38(1):83. Epub 2019 Feb 15.

CAS Key Laboratory of Separation Science for Analytical Chemistry, Scientific Research Center for Translational Medicine, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.

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February 2019

Nonmosaic somatic HIF2A mutations associated with late onset polycythemia-paraganglioma syndrome: Newly recognized subclass of polycythemia-paraganglioma syndrome.

Cancer 2019 04 15;125(8):1258-1266. Epub 2019 Jan 15.

Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.

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April 2019

CHCHD10 is involved in the development of Parkinson's disease caused by CHCHD2 loss-of-function mutation p.T61I.

Neurobiol Aging 2019 03 23;75:38-41. Epub 2018 Oct 23.

Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, Henan, China. Electronic address:

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March 2019

Repurposing propranolol as an antitumor agent in von Hippel-Lindau disease.

J Neurosurg 2018 Oct 1:1-9. Epub 2018 Oct 1.

1Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.

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October 2018

Inhibition of Protein Phosphatase 2A Sensitizes Mucoepidermoid Carcinoma to Chemotherapy via the PI3K-AKT Pathway in Response to Insulin Stimulus.

Cell Physiol Biochem 2018 3;50(1):317-331. Epub 2018 Oct 3.

Department of Oral Pathology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, National Clinical Research Center for Oral Diseases, Shanghai, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China.

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November 2018

Hemangioblast: origin of hemangioblastoma in von Hippel-Lindau (VHL) syndrome.

Oncoscience 2018 Jul 22;5(7-8):212-213. Epub 2018 Aug 22.

Chi-Chao Chan: National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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July 2018

Expression of hypoxia-inducible factor-1a predicts benefit from rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone in diffuse large B-cell lymphoma.

Int J Clin Exp Pathol 2018 1;11(9):4472-4482. Epub 2018 Sep 1.

Department of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, People's Republic of China.

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September 2018

Pharmacologic inhibition of protein phosphatase-2A achieves durable immune-mediated antitumor activity when combined with PD-1 blockade.

Nat Commun 2018 05 29;9(1):2126. Epub 2018 May 29.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892, USA.

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May 2018

Isocitrate dehydrogenase 2 mutations correlate with leukemic transformation and are predicted by 2-hydroxyglutarate in myelodysplastic syndromes.

J Cancer Res Clin Oncol 2018 Jun 16;144(6):1037-1047. Epub 2018 Mar 16.

Department of Hematology, The First Affiliated Hospital, Zhejiang University, No. 79 Qingchun Road, Hangzhou, 310003, People's Republic of China.

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June 2018

A novel splicing site IRP1 somatic mutation in a patient with pheochromocytoma and JAK2 positive polycythemia vera: a case report.

BMC Cancer 2018 03 13;18(1):286. Epub 2018 Mar 13.

Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.

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March 2018

Recurrent somatic mutations of in isolated cardiac myxoma.

Oncotarget 2017 Nov 19;8(61):103968-103974. Epub 2017 Oct 19.

Scientific Research Center for Translational Medicine, Department of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.

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November 2017

Fatty acid oxidation contributes to IL-1β secretion in M2 macrophages and promotes macrophage-mediated tumor cell migration.

Mol Immunol 2018 02 15;94:27-35. Epub 2017 Dec 15.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892, USA; Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, 20892, USA. Electronic address:

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February 2018

Whole-exome sequencing of oral mucosal melanoma reveals mutational profile and therapeutic targets.

J Pathol 2018 03 5;244(3):358-366. Epub 2018 Feb 5.

Bio-X Institutes, Ministry of Education Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Institute of Social Cognitive and Behavioral Sciences, Shanghai Jiao Tong University, Shanghai, PR China.

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March 2018

Probing impaired neurogenesis in human brain organoids exposed to alcohol.

Integr Biol (Camb) 2017 Dec;9(12):968-978

Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, China.

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December 2017

Publisher Correction: PP2A inhibition from LB100 therapy enhances daunorubicin cytotoxicity in secondary acute myeloid leukemia via miR-181b-1 upregulation.

Sci Rep 2017 11 7;7(1):15260. Epub 2017 Nov 7.

Department of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, People's Republic of China.

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November 2017

Global Metabolic Profiling Identifies a Pivotal Role of Proline and Hydroxyproline Metabolism in Supporting Hypoxic Response in Hepatocellular Carcinoma.

Clin Cancer Res 2018 01 30;24(2):474-485. Epub 2017 Oct 30.

Scientific Research Center for Translational Medicine, Department of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.

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January 2018

Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha.

Oncotarget 2017 Aug 23;8(34):56110-56125. Epub 2017 May 23.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.

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August 2017

PP2A inhibition from LB100 therapy enhances daunorubicin cytotoxicity in secondary acute myeloid leukemia via miR-181b-1 upregulation.

Sci Rep 2017 06 6;7(1):2894. Epub 2017 Jun 6.

Department of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, People's Republic of China.

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June 2017

Histone Deacetylase Inhibitor SAHA Is a Promising Treatment of Cushing Disease.

J Clin Endocrinol Metab 2017 08;102(8):2825-2835

Neurosurgery Unit for Pituitary and Inheritable Diseases, National Institute of Neurologic Diseases and Stroke, Bethesda, Maryland 20892.

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August 2017

Anthracyclines suppress pheochromocytoma cell characteristics, including metastasis, through inhibition of the hypoxia signaling pathway.

Oncotarget 2017 Apr;8(14):22313-22324

Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.

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April 2017

Genotype-phenotype correlations in Chinese von Hippel-Lindau disease patients.

Oncotarget 2017 Jun;8(24):38456-38465

Department of Urology, Peking University First Hospital, Beijing, P.R China.

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June 2017

Increase in the radioresistance of normal skin fibroblasts but not tumor cells by mechanical injury.

Cell Death Dis 2017 02 2;8(2):e2573. Epub 2017 Feb 2.

Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.

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February 2017

Somatostatin receptor expression on von Hippel-Lindau-associated hemangioblastomas offers novel therapeutic target.

Sci Rep 2017 01 17;7:40822. Epub 2017 Jan 17.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.

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January 2017

Characterization of the blood brain barrier in pediatric central nervous system neoplasms.

J Interdiscip Histopathol 2016 ;4(2):29-33

Department of Surgical Neurology Branch, National Institutes of Health, Bethesda, MD 20892, USA.

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January 2016

A dynamic in vivo-like organotypic blood-brain barrier model to probe metastatic brain tumors.

Sci Rep 2016 11 10;6:36670. Epub 2016 Nov 10.

Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.

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November 2016

Erythrocytosis in hepatocellular carcinoma portends poor prognosis by respiratory dysfunction secondary to mitochondrial DNA mutations.

Hepatology 2017 01 25;65(1):134-151. Epub 2016 Nov 25.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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January 2017

ZEB1 expression is increased in IDH1-mutant lower-grade gliomas.

J Neurooncol 2016 10 27;130(1):111-122. Epub 2016 Aug 27.

Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke, 9000 Rockville Pike, Building 10 Room 3D17, Bethesda, MD, 20892, USA.

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October 2016

Loss of Quiescence in von Hippel-Lindau Hemangioblastomas is Associated with Erythropoietin Signaling.

Sci Rep 2016 10 17;6:35486. Epub 2016 Oct 17.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.

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October 2016

Pseudo-dominant inheritance of a novel double GLA mutation associated with Fabry disease mimicking familial episodic pain.

Am J Med Genet A 2016 11 17;170(11):3051-3053. Epub 2016 Aug 17.

Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, Henan, China.

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November 2016

HIF2A gain-of-function mutations detected in duodenal gangliocytic paraganglioma.

Endocr Relat Cancer 2016 05 29;23(5):L13-6. Epub 2016 Apr 29.

Section on Medical NeuroendocrinologyEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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May 2016

Application of Peptide Nucleic Acid-based Assays Toward Detection of Somatic Mosaicism.

Mol Ther Nucleic Acids 2016 Apr 26;5:e314. Epub 2016 Apr 26.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.

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April 2016

Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signaling.

Oncotarget 2016 Mar;7(12):15200-14

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.

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March 2016

Metabolomics Study of Roux-en-Y Gastric Bypass Surgery (RYGB) to Treat Type 2 Diabetes Patients Based on Ultraperformance Liquid Chromatography-Mass Spectrometry.

J Proteome Res 2016 Apr 25;15(4):1288-99. Epub 2016 Feb 25.

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences , 457 Zhongshan Road, Dalian 116023, China.

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April 2016

Integration of Metabolomics and Transcriptomics Reveals Major Metabolic Pathways and Potential Biomarker Involved in Prostate Cancer.

Mol Cell Proteomics 2016 Jan 6;15(1):154-63. Epub 2015 Nov 6.

From the ‡Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, China,

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January 2016

Somatic IDH1 mutation in a pituitary adenoma of a patient with Maffucci syndrome.

J Neurosurg 2016 Jun 16;124(6):1562-7. Epub 2015 Oct 16.

National Institute of Neurological Disorders and Stroke, Surgical Neurology Branch, National Institutes of Health, Bethesda, Maryland.

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June 2016

Hypoxia and glioblastoma therapy.

Aging (Albany NY) 2015 Aug;7(8):523-4

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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August 2015

Pheochromocytoma: Gasping for Air.

Horm Cancer 2015 Dec 3;6(5-6):191-205. Epub 2015 Jul 3.

Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver NICHD, National Institutes of Health, Building 10, CRC, 1-East, Room 1E-3140, 10 Center Drive, MSC-1109, Bethesda, MD, 20892-1109, USA.

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December 2015

Potential therapeutic target for malignant paragangliomas: ATP synthase on the surface of paraganglioma cells.

Am J Cancer Res 2015 15;5(4):1558-70. Epub 2015 Mar 15.

Program on Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health Bethesda, MD 20892, USA.

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June 2015

LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential.

Cancer Biol Ther 2015 21;16(6):821-33. Epub 2015 Apr 21.

a The Ohio State University Wexner Medical Center ; Department of Neurological Surgery ; Columbus , OH USA.

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March 2016

New developments in the pathogenesis and therapeutic targeting of the IDH1 mutation in glioma.

Int J Med Sci 2015 20;12(3):201-13. Epub 2015 Jan 20.

2. Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA.

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November 2015

Mutant glucocerebrosidase in Gaucher disease recruits Hsp27 to the Hsp90 chaperone complex for proteasomal degradation.

Proc Natl Acad Sci U S A 2015 Jan 12;112(4):1137-42. Epub 2015 Jan 12.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892

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January 2015

The role of Cullin3-mediated ubiquitination of the catalytic subunit of PP2A in TRAIL signaling.

Cell Cycle 2014 ;13(23):3750-8

a Departments of Oncology and Pathology; Karmanos Cancer Institute ; Wayne State University School of Medicine ; Detroit , MI USA.

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September 2015

Somatic mosaicism of EPAS1 mutations in the syndrome of paraganglioma and somatostatinoma associated with polycythemia.

Hum Genome Var 2015 10;2:15053. Epub 2015 Dec 10.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health , Bethesda, MD, USA.

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April 2016

Cell transcriptional state alters genomic patterns of DNA double-strand break repair in human astrocytes.

Nat Commun 2014 Dec 17;5:5799. Epub 2014 Dec 17.

1] Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA [2] Department of Neurological Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210, USA.

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December 2014

Fab fragment glycosylated IgG may play a central role in placental immune evasion.

Hum Reprod 2015 Feb 11;30(2):380-91. Epub 2014 Dec 11.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, NIH, Building 10, Room 5D 37, 10 Center Drive, Bethesda, MD 20892, USA.

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February 2015

A morphologic and semi-quantitative technique to analyze synthesis and release of specific proteins in cells.

BMC Cell Biol 2014 Dec 5;15:45. Epub 2014 Dec 5.

Department of Pathology and Pathophysiology, Guangdong Provincial Key Laboratory of Infectious Disease and Immunopathology, Shantou University Medical College, Shantou, Guangdong, 515041, China.

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December 2014

The protein phosphatase 2A inhibitor LB100 sensitizes ovarian carcinoma cells to cisplatin-mediated cytotoxicity.

Mol Cancer Ther 2015 Jan 5;14(1):90-100. Epub 2014 Nov 5.

Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.

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January 2015

Inhibition of protein phosphatase 2A sensitizes pancreatic cancer to chemotherapy by increasing drug perfusion via HIF-1α-VEGF mediated angiogenesis.

Cancer Lett 2014 Dec 7;355(2):281-7. Epub 2014 Oct 7.

Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Cancer Prevention and Intervention, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Electronic address:

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December 2014

Alcohol consumption and risk of myelodysplastic syndromes: A meta-analysis of epidemiological studies.

Mol Clin Oncol 2014 Nov 7;2(6):1115-1120. Epub 2014 Aug 7.

Department of Hematology, The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China ; Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, P.R. China.

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November 2014

Germ-line PHD1 and PHD2 mutations detected in patients with pheochromocytoma/paraganglioma-polycythemia.

J Mol Med (Berl) 2015 Jan 30;93(1):93-104. Epub 2014 Sep 30.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.

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January 2015

Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair.

Oncotarget 2014 Sep;5(17):7512-24

Cancer Institute and Hospital, Chinese Academy of Medical Sciences (CAMS) ,Beijing , People's Republic of China. Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong , People's Republic of China. State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong , People's Republic of China.

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September 2014

Ocular manifestations of hypoxia-inducible factor-2α paraganglioma-somatostatinoma-polycythemia syndrome.

Ophthalmology 2014 Nov 8;121(11):2291-3. Epub 2014 Aug 8.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.

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November 2014

Prognostic value of isocitrate dehydrogenase mutations in myelodysplastic syndromes: a retrospective cohort study and meta-analysis.

PLoS One 2014 17;9(6):e100206. Epub 2014 Jun 17.

Department of Hematology, the First Affiliated Hospital of Zhejiang University, Hangzhou, People's Republic of China; Institute of Hematology, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.

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October 2015

Sequential combination of decitabine and idarubicin synergistically enhances anti-leukemia effect followed by demethylating Wnt pathway inhibitor promoters and downregulating Wnt pathway nuclear target.

J Transl Med 2014 Jun 12;12:167. Epub 2014 Jun 12.

Department of Hematology, the First Affiliated Hospital of Zhejiang University, Hangzhou 310003, Zhejiang Province, People's Republic of China.

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June 2014

Von hippel-lindau disease associated pulmonary carcinoid with cranial metastasis.

J Clin Endocrinol Metab 2014 Aug 30;99(8):2633-6. Epub 2014 May 30.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke (C.Z., A.I.Y., C.Y., C.L.N., P.C., J.D.H., Z.Z., K.A.Z.), and Laboratory of Pathology, National Cancer Institute (L.V., S.M., L.S., Z.A., S.D.P., A.G., M.M.Q.), National Institutes of Health, Bethesda, Maryland 20892; and Department of Orthopedics (C.Z.), Xinqiao Hospital, The Third Military Medical University, Chongqing 400037, China.

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August 2014

Upregulation of hypoxia-inducible factors and autophagy in von Hippel-Lindau-associated retinal hemangioblastoma.

Graefes Arch Clin Exp Ophthalmol 2014 Aug 24;252(8):1319-27. Epub 2014 May 24.

Immunopathology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, 10 Center Dr., 10/10N103, NIH/NEI, Bethesda, MD, 20892-1857, USA,

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August 2014

De novo VHL germline mutation detected in a patient with mild clinical phenotype of von Hippel-Lindau disease.

J Neurosurg 2014 Aug 28;121(2):384-386. Epub 2014 Mar 28.

Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.

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August 2014

Tumor derived vasculogenesis in von Hippel-Lindau disease-associated tumors.

Sci Rep 2014 Feb 17;4:4102. Epub 2014 Feb 17.

1] Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD [2] Department of Neurological Surgery, The Ohio State University Wexner Medical Center, Department of Neurological Surgery, Columbus, Ohio.

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February 2014