Publications by authors named "Zhenggang Zhu"

100Publications

Downregulation of CDH11 Promotes Metastasis and Resistance to Paclitaxel in Gastric Cancer Cells.

J Cancer 2021 1;12(1):65-75. Epub 2021 Jan 1.

Department of General Surgery, Gastrointestinal Surgery, Shanghai Key laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

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January 2021

Microsatellite Status Affects Tumor Response and Survival in Patients Undergoing Neoadjuvant Chemotherapy for Clinical Stage III Gastric Cancer.

Front Oncol 2020 15;10:614785. Epub 2020 Dec 15.

Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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December 2020

Neoadjuvant FLOT versus SOX phase II randomized clinical trial for patients with locally advanced gastric cancer.

Nat Commun 2020 11 30;11(1):6093. Epub 2020 Nov 30.

Department of General Surgery, Gastrointestinal Surgery Unit, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Shanghai, China.

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November 2020

Artificial Intelligence-Based Multiclass Classification of Benign or Malignant Mucosal Lesions of the Stomach.

Front Pharmacol 2020 2;11:572372. Epub 2020 Oct 2.

Center for Intelligent Medical Imaging & Health, Research Institute of Tsinghua University in Shenzhen, Shenzhen, China.

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October 2020

Complications and risk factors for complications of implanted subcutaneous ports for intraperitoneal chemotherapy in gastric cancer with peritoneal metastasis.

Chin J Cancer Res 2020 Aug;32(4):497-507

Department of General Surgery, Gastrointestinal Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

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August 2020

Postoperative BMI Loss at One Year Correlated with Poor Outcomes in Chinese Gastric Cancer Patients.

Int J Med Sci 2020 25;17(15):2276-2284. Epub 2020 Aug 25.

Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin er Road, Shanghai, 200025, China.

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August 2020

Activation of astrocytes in hippocampus decreases fear memory through adenosine A receptors.

Elife 2020 09 1;9. Epub 2020 Sep 1.

Department of Neurobiology and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

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September 2020

Genetic Profiles Affect the Biological Effects of Serine on Gastric Cancer Cells.

Front Pharmacol 2020 31;11:1183. Epub 2020 Jul 31.

Department of Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, and Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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July 2020

The prognostic value of HGF-c-MET signaling pathway in Gastric Cancer: a study based on TCGA and GEO databases.

Int J Med Sci 2020 19;17(13):1946-1955. Epub 2020 Jul 19.

Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin er Road, Shanghai, 200025, China.

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July 2020

Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels.

Int J Biol Sci 2020 27;16(13):2382-2391. Epub 2020 Jun 27.

Emergency Department, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 200025, Shanghai, China.

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August 2020

Stearoyl-CoA desaturase 1 (SCD1) facilitates the growth and anti-ferroptosis of gastric cancer cells and predicts poor prognosis of gastric cancer.

Aging (Albany NY) 2020 07 29;12(15):15374-15391. Epub 2020 Jul 29.

Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

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July 2020

Modified surface measurement method to determine catheter tip position of totally implantable venous access port through right subclavian vein.

J Vasc Surg Venous Lymphat Disord 2020 Jul 26. Epub 2020 Jul 26.

Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

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July 2020

Effect of apatinib plus neoadjuvant chemotherapy followed by resection on pathologic response in patients with locally advanced gastric adenocarcinoma: A single-arm, open-label, phase II trial.

Eur J Cancer 2020 05 11;130:12-19. Epub 2020 Mar 11.

Department of Gastrointestinal Surgery, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai, China. Electronic address:

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May 2020

A study of capecitabine metronomic chemotherapy is non-inferior to conventional chemotherapy as maintenance strategy in responders after induction therapy in metastatic colorectal cancer.

Trials 2020 Mar 6;21(1):249. Epub 2020 Mar 6.

Department of Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijin Er Road, Shanghai, 200025, China.

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March 2020

Characterization of the immune microenvironment in brain metastases from different solid tumors.

Cancer Med 2020 04 4;9(7):2299-2308. Epub 2020 Feb 4.

Department of Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

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April 2020

Machine-learning-assisted prediction of surgical outcomes in patients undergoing gastrectomy.

Chin J Cancer Res 2019 Oct;31(5):797-805

Department of Chemistry, College of Sciences, Shanghai University, Shanghai 200444, China.

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October 2019

Severe multiple rabid dog bite injuries in a child in central China: Continuous 10-year observation and analysis on this case.

Hum Vaccin Immunother 2020 04 11;16(4):904-906. Epub 2019 Nov 11.

Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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April 2020

A self-enforcing HOXA11/Stat3 feedback loop promotes stemness properties and peritoneal metastasis in gastric cancer cells.

Theranostics 2019 14;9(25):7628-7647. Epub 2019 Oct 14.

Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin er Road, Shanghai, 200025, China.

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September 2020

Dose-finding study of modified FLOT (mFLOT) regimen as first-line treatment in Chinese patients with metastatic adenocarcinoma of stomach.

Cancer Chemother Pharmacol 2020 01 5;85(1):113-119. Epub 2019 Nov 5.

Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China.

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January 2020

The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis.

Oncogene 2020 02 28;39(7):1414-1428. Epub 2019 Oct 28.

Department of Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 200025, Shanghai, People's Republic of China.

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February 2020

Pre-treatment inflammatory biomarkers predict early treatment response and favorable survival in patients with metastatic colorectal cancer who underwent first line cetuximab plus chemotherapy.

Cancer Manag Res 2019 24;11:8657-8668. Epub 2019 Sep 24.

Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, People's Republic of China.

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September 2019

Expression pattern of CDK12 protein in gastric cancer and its positive correlation with CD8 cell density and CCL12 expression.

Int J Med Sci 2019 6;16(8):1142-1148. Epub 2019 Aug 6.

Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin er Road, Shanghai, 200025, China.

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January 2020

HUPAN: a pan-genome analysis pipeline for human genomes.

Genome Biol 2019 07 31;20(1):149. Epub 2019 Jul 31.

School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China.

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July 2019

Overexpression of CrkL as a novel biomarker for poor prognosis in gastric cancer.

Cancer Biomark 2019 ;26(2):131-138

Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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March 2020

A positive feedback between IDO1 metabolite and COL12A1 via MAPK pathway to promote gastric cancer metastasis.

J Exp Clin Cancer Res 2019 Jul 17;38(1):314. Epub 2019 Jul 17.

Department of Surgery of Ruijin Hospital, and Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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July 2019

A Novel Citrullinated Modification of Histone 3 and Its Regulatory Mechanisms Related to IPO-38 Antibody-Labeled Protein.

Front Oncol 2019 18;9:304. Epub 2019 Apr 18.

Department of Surgery, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai, China.

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April 2019

Response to letter to the editor on analysis.

Hum Vaccin Immunother 2019 3;15(9):2127-2128. Epub 2019 May 3.

Department of Leprosy, Wuhan Institute of Dermatology and Venereology , Wuhan , China.

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October 2019

miR-106b Promotes Metastasis of Early Gastric Cancer by Targeting ALEX1 in Vitro and in Vivo.

Cell Physiol Biochem 2019 ;52(3):606-616

Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China,

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April 2019

LncRNAs GIHCG and SPINT1-AS1 Are Crucial Factors for Pan-Cancer Cells Sensitivity to Lapatinib.

Front Genet 2019 19;10:25. Epub 2019 Feb 19.

Department of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA, United States.

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February 2019

Oncostatin M receptor, positively regulated by SP1, promotes gastric cancer growth and metastasis upon treatment with Oncostatin M.

Gastric Cancer 2019 09 18;22(5):955-966. Epub 2019 Feb 18.

Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

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September 2019

CD36 mediates palmitate acid-induced metastasis of gastric cancer via AKT/GSK-3β/β-catenin pathway.

J Exp Clin Cancer Res 2019 Feb 4;38(1):52. Epub 2019 Feb 4.

Department of Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.

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February 2019

[Analysis of clinical features and prognostic factors on reoperation patients with postoperative recurrence or metastasis of gastrointestinal stromal tumor].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Nov;21(11):1274-1279

Ward III Gastrointestinal Surgery, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai 200025,

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November 2018

KIF14 promotes tumor progression and metastasis and is an independent predictor of poor prognosis in human gastric cancer.

Biochim Biophys Acta Mol Basis Dis 2019 01 4;1865(1):181-192. Epub 2018 Nov 4.

Shanghai Key laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

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January 2019

[Therapeutic arrangement and strategies in perioperative treatment of locally advanced gastric cancer from the view of whole-process management].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Oct;21(10):1093-1098

Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai 200025, China.

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October 2018

[Clinical significance and efficacy of conversion surgery for patients with stage IV gastric cancer].

Authors:
Zhenggang Zhu

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Oct;21(10):1087-1092

Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory of Gastric Neoplasm, Shanghai 200025, China Email:

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October 2018

Difference of molecular alterations in HER2-positive and HER2-negative gastric cancers by whole-genome sequencing analysis.

Cancer Manag Res 2018 26;10:3945-3954. Epub 2018 Sep 26.

Department of Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China,

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September 2018

Analysis on the risks of severe adverse events in rabies post-exposure prophylaxis and appropriate decision-making procedure.

Hum Vaccin Immunother 2019 26;15(9):2121-2125. Epub 2018 Oct 26.

Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , China.

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March 2020

miR-126: An indicator of poor prognosis and recurrence in histologically lymph node-negative gastric cancer.

Cancer Biomark 2018 ;23(3):437-445

Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

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March 2019

HGF-mediated crosstalk between cancer-associated fibroblasts and MET-unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis.

Cell Death Dis 2018 08 29;9(9):867. Epub 2018 Aug 29.

Department of Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijin Er Road, Shanghai, 200025, China.

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August 2018

Cross-Database Analysis Reveals Sensitive Biomarkers for Combined Therapy for ERBB2+ Gastric Cancer.

Front Pharmacol 2018 3;9:861. Epub 2018 Aug 3.

Department of Surgery, Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai, China.

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August 2018

UBE2C Is a Potential Biomarker of Intestinal-Type Gastric Cancer With Chromosomal Instability.

Front Pharmacol 2018 2;9:847. Epub 2018 Aug 2.

Department of Surgery, Ruijin Hospital, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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August 2018

HGF derived from cancer‑associated fibroblasts promotes vascularization in gastric cancer via PI3K/AKT and ERK1/2 signaling.

Oncol Rep 2018 Aug 18;40(2):1185-1195. Epub 2018 Jun 18.

Department of Oncology, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P.R. China.

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August 2018

Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer.

Biochim Biophys Acta Mol Basis Dis 2018 09 23;1864(9 Pt B):2835-2844. Epub 2018 May 23.

Department of Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

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September 2018

Down-regulated serum miR-126 is associated with aggressive progression and poor prognosis of gastric cancer.

Cancer Biomark 2018 ;22(1):119-126

Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

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October 2018

[2017 hotspots review and outlook on gastric cancer surgery in China].

Authors:
Zhenggang Zhu

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Jan;21(1):7-14

Department of Surgery, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory of Gastric Neoplasm, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

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January 2018

Metronomic chemotherapy remodel cancer-associated fibroblasts to decrease chemoresistance of gastric cancer in nude mice.

Oncol Lett 2017 Dec 16;14(6):7903-7909. Epub 2017 Oct 16.

Department of Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P.R. China.

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December 2017

Comprehensive treatment of unresectable cardiac angiosarcoma: A case report and review of literature.

Mol Clin Oncol 2017 Nov 24;7(5):859-863. Epub 2017 Aug 24.

Department of Oncology, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, P.R. China.

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November 2017

Dysregulation of miR-126/Crk protein axis predicts poor prognosis in gastric cancer patients.

Cancer Biomark 2018 Feb;21(2):335-343

Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

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February 2018

[Clinical significance and practice points of conversion therapy for gastric cancer with peritoneal metastasis].

Authors:
Zhenggang Zhu

Zhonghua Wei Chang Wai Ke Za Zhi 2017 Oct;20(10):1094-1098

Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory of Gastric Neoplasm, Shanghai 200025, China.

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October 2017

, a microtubule-associated protein, promotes tumor growth and progression of human gastric cancer.

Oncotarget 2017 Sep 10;8(43):74479-74493. Epub 2017 Aug 10.

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, People's Republic of China.

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September 2017

Integrative bioinformatics analysis identifies ROBO1 as a potential therapeutic target modified by miR-218 in hepatocellular carcinoma.

Oncotarget 2017 Sep 23;8(37):61327-61337. Epub 2017 May 23.

Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 20025, People's Republic of China.

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September 2017

Dual role of carcinoembryonic antigen-related cell adhesion molecule 6 expression in predicting the overall survival of gastric cancer patients.

Sci Rep 2017 09 7;7(1):10773. Epub 2017 Sep 7.

Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.

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September 2017

Long noncoding RNA UCA1 promotes tumour metastasis by inducing GRK2 degradation in gastric cancer.

Cancer Lett 2017 11 23;408:10-21. Epub 2017 Aug 23.

Department of Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, PR China. Electronic address:

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November 2017

Luteolin suppresses angiogenesis and vasculogenic mimicry formation through inhibiting Notch1-VEGF signaling in gastric cancer.

Biochem Biophys Res Commun 2017 08 24;490(3):913-919. Epub 2017 Jun 24.

Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, People's Republic of China. Electronic address:

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August 2017

PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer.

Sci Rep 2017 06 6;7(1):2886. Epub 2017 Jun 6.

Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai, 200025, China.

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June 2017

Cancer-associated fibroblast-derived Lumican promotes gastric cancer progression via the integrin β1-FAK signaling pathway.

Int J Cancer 2017 09 21;141(5):998-1010. Epub 2017 Jun 21.

Department of Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.

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September 2017

[Application and development of patient-derived tumor xenograft model in translational medicine of tumor].

Zhonghua Wei Chang Wai Ke Za Zhi 2017 May;20(5):596-600

Department of Digestive Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.

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May 2017

Dynamic covalent linked triblock copolymer micelles for glutathione-mediated intracellular drug delivery.

Mater Sci Eng C Mater Biol Appl 2017 Aug 27;77:34-44. Epub 2017 Mar 27.

Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address:

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August 2017

A hydrophobic residue in the TALE homeodomain of PBX1 promotes epithelial-to-mesenchymal transition of gastric carcinoma.

Oncotarget 2017 Jul;8(29):46818-46833

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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July 2017

Biocompatible aggregation-induced emission nanoparticles with red emission for in vivo three-photon brain vascular imaging.

J Mater Chem B 2017 Apr 27;5(15):2757-2762. Epub 2017 Mar 27.

State Key Laboratory of Modern Optical Instrumentations, Centre for Optical and Electromagnetic Research, College of Optical Science and Engineering, Zhejiang University, Hangzhou 310058, China.

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April 2017

Fbxw7 haploinsufficiency loses its protection against DNA damage and accelerates MNU-induced gastric carcinogenesis.

Oncotarget 2017 May;8(20):33444-33456

Department of Surgery of Shanghai Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

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May 2017

Characterization of exosomal RNAs derived from human gastric cancer cells by deep sequencing.

Tumour Biol 2017 Apr;39(4):1010428317695012

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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April 2017

Deubiquitinating enzyme USP20 is a positive regulator of Claspin and suppresses the malignant characteristics of gastric cancer cells.

Int J Oncol 2017 Mar 8. Epub 2017 Mar 8.

Department of Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P.R. China.

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March 2017

ADAM9 functions as a promoter of gastric cancer growth which is negatively and post-transcriptionally regulated by miR-126.

Oncol Rep 2017 Apr 16;37(4):2033-2040. Epub 2017 Feb 16.

Department of Surgery, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, P.R. China.

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April 2017

IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway.

Oncotarget 2017 Mar;8(13):20741-20750

Department of Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, People's Republic of China.

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March 2017

microRNA-29c inhibits cell proliferation by targeting NASP in human gastric cancer.

BMC Cancer 2017 Feb 7;17(1):109. Epub 2017 Feb 7.

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No.197 Ruijin Er Road, Shanghai, 200025, People's Republic of China.

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February 2017

Preoperative Chemotherapy for Gastric Cancer: Personal Interventions and Precision Medicine.

Biomed Res Int 2016 25;2016:3923585. Epub 2016 Dec 25.

Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University, Shanghai 200025, China.

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January 2017

ABCG2 confers promotion in gastric cancer through modulating downstream CRKL in vitro combining with biostatistics mining.

Oncotarget 2017 Jan;8(3):5256-5267

Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 20025, People's Republic of China.

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January 2017

[Efficacy and safety of surgery combined with hyperthermic intraperitoneal chemotherapy in the treatment of advanced gastric cancer: a meta-analysis].

Zhonghua Wei Chang Wai Ke Za Zhi 2016 Dec;19(12):1406-1413

Department of General Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai 200025, China.

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December 2016

Safety comparison of four types of rabies vaccines in patients with WHO category II animal exposure: An observation based on different age groups.

Medicine (Baltimore) 2016 Nov;95(47):e5049

Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan Centers for Disease Control and Prevention, Wuhan, China.

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November 2016

SLC7A5 Functions as a Downstream Target Modulated by CRKL in Metastasis Process of Gastric Cancer SGC-7901 Cells.

PLoS One 2016 15;11(11):e0166147. Epub 2016 Nov 15.

Department of Data Science, University of Mississippi Medical Center, Jackson, Mississippi, United States of America.

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June 2017

Regulator of G-protein signaling 3 targeted by miR-126 correlates with poor prognosis in gastric cancer patients.

Anticancer Drugs 2017 02;28(2):161-169

Departments of aSurgery bPathology cShanghai Key Laboratory of Gastric Neoplasms dShanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China eDepartment of Data Science, University of Mississippi Medical Center, Jackson, Mississippi, USA.

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February 2017

EGFR High Expression, but not KRAS Status, Predicts Sensitivity of Pancreatic Cancer Cells to Nimotuzumab Treatment In Vivo.

Curr Cancer Drug Targets 2017 ;17(1):89-97

Department of Oncology, RuiJin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijiner Road, Shanghai 200025, China.

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October 2017

A characteristic biosignature for discrimination of gastric cancer from healthy population by high throughput GC-MS analysis.

Oncotarget 2016 Dec;7(52):87496-87510

Department of Surgery of Ruijin Hospital, and Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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December 2016

MiR-148a Functions as a Tumor Suppressor by Targeting CCK-BR via Inactivating STAT3 and Akt in Human Gastric Cancer.

PLoS One 2016 12;11(8):e0158961. Epub 2016 Aug 12.

Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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July 2017

Effect of urokinase-type plasminogen activator system in gastric cancer with peritoneal metastasis.

Oncol Lett 2016 Jun 26;11(6):4208-4216. Epub 2016 Apr 26.

Department of Gastroenterological Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, P.R. China.

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June 2016

[Clinical and prognostic features of surgical treatment in gastric cancer in aged patients].

Zhonghua Wei Chang Wai Ke Za Zhi 2016 May;19(5):596-600

Department of Surgery, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai 200025, China.

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May 2016

[Analysis of clinicopathological features and risk factors for postoperative complications in the elderly gastric cancer patients].

Zhonghua Wei Chang Wai Ke Za Zhi 2016 May;19(5):514-21

Department of Surgery, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai 200025, China.

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May 2016

[Full attention to several key issues in surgical treatment for the elderly patients with gastrointestinal cancer].

Authors:
Zhenggang Zhu

Zhonghua Wei Chang Wai Ke Za Zhi 2016 May;19(5):486-9

Department of Surgery, RuiJin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai 200025, China.

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May 2016

Suppressive effects on cell proliferation and motility in gastric cancer SGC-7901 cells by introducing ulinastatin in vitro.

Anticancer Drugs 2016 08;27(7):651-9

aDepartment of Surgery bShanghai Key Laboratory of Gastric Neoplasms cShanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China dDepartment of Clinical Science, Quantitative Biomedical Research Center, UT Southwestern Medical Center, Dallas, Texas, USA.

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August 2016

REG4 promotes peritoneal metastasis of gastric cancer through GPR37.

Oncotarget 2016 May;7(19):27874-88

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, People's Republic of China.

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May 2016

Mitochondrial aldehyde dehydrogenase 2 protects gastric mucosa cells against DNA damage caused by oxidative stress.

Free Radic Biol Med 2016 Apr 5;93:165-76. Epub 2016 Feb 5.

Department of Surgery, Ruijin Hospital, Shanghai Institute of Digestive Surgery and Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin er Road, Shanghai 200025, People's Republic of China; Collaborative Innovation Center of Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200025, People's Republic of China. Electronic address:

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April 2016

[Present status of preoperative staging and contemplation on preoperative precision staging for gastric cancer].

Authors:
Zhenggang Zhu

Zhonghua Wei Chang Wai Ke Za Zhi 2016 Feb;19(2):126-31

Department of Surgery, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai 200025, China.

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February 2016

Tissue transglutaminase-2 promotes gastric cancer progression via the ERK1/2 pathway.

Oncotarget 2016 Feb;7(6):7066-79

Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.

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February 2016

ZHX1 Inhibits Gastric Cancer Cell Growth through Inducing Cell-Cycle Arrest and Apoptosis.

J Cancer 2016 1;7(1):60-8. Epub 2016 Jan 1.

Department of Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

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January 2016

Identification of Serum Biomarkers for Gastric Cancer Diagnosis Using a Human Proteome Microarray.

Mol Cell Proteomics 2016 Feb 23;15(2):614-23. Epub 2015 Nov 23.

From the Shanghai Center for Systems Biomedicine, Ministry of Education Key Laboratory of Systems Biomedicine, and Shanghai Key Laboratory of Gastric Neoplasms, Ruijin Hospital, Shanghai Jiao Tong University, Shanghai, 200240, China; State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University, Shanghai, 200240, China;

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February 2016

DBGC: A Database of Human Gastric Cancer.

PLoS One 2015 13;10(11):e0142591. Epub 2015 Nov 13.

School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai, China.

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July 2016

HOXB9 induction of mesenchymal-to-epithelial transition in gastric carcinoma is negatively regulated by its hexapeptide motif.

Oncotarget 2015 Dec;6(40):42838-53

Department of Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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December 2015

[Clinical efficacy of paclitaxel combined with S-1 in the prevention and treatment of gastric cancer with peritoneal metastasis].

Authors:
Zhenggang Zhu

Zhonghua Wei Chang Wai Ke Za Zhi 2015 Oct;18(10):979-82

Department of Surgery, Ruijing Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai 200025, China.

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October 2015

Decreased expression of long non-coding RNA WT1-AS promotes cell proliferation and invasion in gastric cancer.

Biochim Biophys Acta 2016 01 9;1862(1):12-9. Epub 2015 Oct 9.

Shanghai Key laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of medicine, No 197 Ruijin er Road, Shanghai 200025, China. Electronic address:

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January 2016

MicroRNA-126 inhibits cell proliferation in gastric cancer by targeting LAT-1.

Biomed Pharmacother 2015 May 14;72:66-73. Epub 2015 Apr 14.

Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, 197, Rui Jin Er Road, Shanghai 20025, People's Republic of China; Shanghai Key Laboratory of Gastric Neoplasms, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, 197, Rui Jin Er Road, Shanghai 20025, People's Republic of China; Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, 197, Rui Jin Er Road, Shanghai 20025, People's Republic of China.

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May 2015

MTA2 enhances colony formation and tumor growth of gastric cancer cells through IL-11.

BMC Cancer 2015 May 2;15:343. Epub 2015 May 2.

Department of Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijin er Road, Shanghai, 200025, China.

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May 2015

Characterization of differentially expressed genes involved in pathways associated with gastric cancer.

PLoS One 2015 30;10(4):e0125013. Epub 2015 Apr 30.

Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, People's Republic of China.

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February 2016

CEACAM6 promotes tumor angiogenesis and vasculogenic mimicry in gastric cancer via FAK signaling.

Biochim Biophys Acta 2015 May 19;1852(5):1020-8. Epub 2015 Feb 19.

Department of Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, People's Republic of China. Electronic address:

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May 2015

Redox-responsive micelles self-assembled from dynamic covalent block copolymers for intracellular drug delivery.

Acta Biomater 2015 Apr 7;17:193-200. Epub 2015 Feb 7.

Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address:

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April 2015

Capecitabine metronomic chemotherapy inhibits the proliferation of gastric cancer cells through anti-angiogenesis.

Oncol Rep 2015 Apr 29;33(4):1753-62. Epub 2015 Jan 29.

Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P.R. China.

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April 2015