Publications by authors named "Zhengdong Zhang"

100Publications

Remote modulation of lncRNA by risk variant at 16p13 underlying genetic susceptibility to gastric cancer.

Sci Adv 2020 May 20;6(21). Epub 2020 May 20.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1126/sciadv.aay5525DOI Listing
May 2020

Relationship between particulate matter exposure and female breast cancer incidence and mortality: a systematic review and meta-analysis.

Int Arch Occup Environ Health 2020 Sep 10. Epub 2020 Sep 10.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, 101 Longmian Avenue Jiangning District, Nanjing, 211166, China.

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http://dx.doi.org/10.1007/s00420-020-01573-yDOI Listing
September 2020

PD-L1, PDK-1 and p-Akt are correlated in patients with papillary thyroid carcinoma.

Adv Clin Exp Med 2020 Jul;29(7):785-792

Department of General Surgery, Shanghai Xuhui Center Hospital, China.

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http://dx.doi.org/10.17219/acem/121518DOI Listing
July 2020

Beaver and Naked Mole Rat Genomes Reveal Common Paths to Longevity.

Cell Rep 2020 Jul;32(4):107949

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107949DOI Listing
July 2020

Genetics of extreme human longevity to guide drug discovery for healthy ageing.

Nat Metab 2020 Aug 27;2(8):663-672. Epub 2020 Jul 27.

Department of Genetics, Albert Einstein College of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1038/s42255-020-0247-0DOI Listing
August 2020

Remote modulation of lncRNA by risk variant at 16p13 underlying genetic susceptibility to gastric cancer.

Sci Adv 2020 May 20;6(21):eaay5525. Epub 2020 May 20.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1126/sciadv.aay5525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314563PMC
May 2020

A transcriptomic study for identifying cardia- and non-cardia-specific gastric cancer prognostic factors using genetic algorithm-based methods.

J Cell Mol Med 2020 Jul 10. Epub 2020 Jul 10.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1111/jcmm.15618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417703PMC
July 2020

Inducible aging in Hydra oligactis implicates sexual reproduction, loss of stem cells, and genome maintenance as major pathways.

Geroscience 2020 Aug 23;42(4):1119-1132. Epub 2020 Jun 23.

Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.

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http://dx.doi.org/10.1007/s11357-020-00214-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394996PMC
August 2020

Genetic variants in Ras/Raf/MEK/ERK pathway are associated with gastric cancer risk in Chinese Han population.

Arch Toxicol 2020 Aug 11;94(8):2683-2690. Epub 2020 Jun 11.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1007/s00204-020-02771-wDOI Listing
August 2020

Parallel isotope differential modeling for instationary 13C fluxomics at the genome scale.

Biotechnol Biofuels 2020 8;13:103. Epub 2020 Jun 8.

Key Laboratory of Information and Computing Science Guizhou Province, Guizhou Normal University, Guiyang, Guizhou China.

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http://dx.doi.org/10.1186/s13068-020-01737-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278083PMC
June 2020

Alternative splicing related genetic variants contribute to bladder cancer risk.

Mol Carcinog 2020 Aug 27;59(8):923-929. Epub 2020 Apr 27.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1002/mc.23207DOI Listing
August 2020

Multiomics Evaluation of Gastrointestinal and Other Clinical Characteristics of COVID-19.

Gastroenterology 2020 Jun 28;158(8):2298-2301.e7. Epub 2020 Mar 28.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China; Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2020.03.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270476PMC
June 2020

Ankle arthrodesis for end-stage haemophilic ankle arthropathy using a Ilizarov method.

Int Orthop 2020 May 3;44(5):995-1001. Epub 2020 Mar 3.

Department of Orthopedics, West China Hospital, Sichuan University, 37# Guoxue Alley, Chengdu, 610041, Sichuan, People's Republic of China.

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http://dx.doi.org/10.1007/s00264-020-04513-0DOI Listing
May 2020

Genetic variations in Hippo pathway genes influence bladder cancer risk in a Chinese population.

Arch Toxicol 2020 03 2;94(3):785-794. Epub 2020 Mar 2.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Nanjing, 211166, Jiangsu, China.

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http://dx.doi.org/10.1007/s00204-020-02663-zDOI Listing
March 2020

MUC1 is associated with TFF2 methylation in gastric cancer.

Clin Epigenetics 2020 03 2;12(1):37. Epub 2020 Mar 2.

Department of Environmental Genomics, School of Public Health, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, China.

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http://dx.doi.org/10.1186/s13148-020-00832-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053135PMC
March 2020

Sex hormones and genetic variants in hormone metabolic pathways associated with the risk of colorectal cancer.

Environ Int 2020 04 18;137:105543. Epub 2020 Feb 18.

State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China; Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China; Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2020.105543DOI Listing
April 2020

Novel CpG-SNPs in the gastric acid secretion pathway GNAI3 and susceptibility to gastric cancer.

Gene 2020 Apr 4;736:144447. Epub 2020 Feb 4.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing, China; Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2020.144447DOI Listing
April 2020

[Identification of potential traumatic spinal cord injury related circular RNA-microRNA networks by sequence analysis].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2020 Feb;34(2):213-219

Department of Orthopedics, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P.R.China.

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http://dx.doi.org/10.7507/1002-1892.201905079DOI Listing
February 2020

Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion.

Authors:
Isabelle Cleynen Worrawat Engchuan Matthew S Hestand Tracy Heung Aaron M Holleman H Richard Johnston Thomas Monfeuga Donna M McDonald-McGinn Raquel E Gur Bernice E Morrow Ann Swillen Jacob A S Vorstman Carrie E Bearden Eva W C Chow Marianne van den Bree Beverly S Emanuel Joris R Vermeesch Stephen T Warren Michael J Owen Pankaj Chopra David J Cutler Richard Duncan Alex V Kotlar Jennifer G Mulle Anna J Voss Michael E Zwick Alexander Diacou Aaron Golden Tingwei Guo Jhih-Rong Lin Tao Wang Zhengdong Zhang Yingjie Zhao Christian Marshall Daniele Merico Andrea Jin Brenna Lilley Harold I Salmons Oanh Tran Peter Holmans Antonio Pardinas James T R Walters Wolfram Demaerel Erik Boot Nancy J Butcher Gregory A Costain Chelsea Lowther Rens Evers Therese A M J van Amelsvoort Esther van Duin Claudia Vingerhoets Jeroen Breckpot Koen Devriendt Elfi Vergaelen Annick Vogels T Blaine Crowley Daniel E McGinn Edward M Moss Robert J Sharkus Marta Unolt Elaine H Zackai Monica E Calkins Robert S Gallagher Ruben C Gur Sunny X Tang Rosemarie Fritsch Claudia Ornstein Gabriela M Repetto Elemi Breetvelt Sasja N Duijff Ania Fiksinski Hayley Moss Maria Niarchou Kieran C Murphy Sarah E Prasad Eileen M Daly Maria Gudbrandsen Clodagh M Murphy Declan G Murphy Antonio Buzzanca Fabio Di Fabio Maria C Digilio Maria Pontillo Bruno Marino Stefano Vicari Karlene Coleman Joseph F Cubells Opal Y Ousley Miri Carmel Doron Gothelf Ehud Mekori-Domachevsky Elena Michaelovsky Ronnie Weinberger Abraham Weizman Leila Kushan Maria Jalbrzikowski Marco Armando Stéphan Eliez Corrado Sandini Maude Schneider Frédérique Sloan Béna Kevin M Antshel Wanda Fremont Wendy R Kates Raoul Belzeaux Tiffany Busa Nicole Philip Linda E Campbell Kathryn L McCabe Stephen R Hooper Kelly Schoch Vandana Shashi Tony J Simon Flora Tassone Celso Arango David Fraguas Sixto García-Miñaúr Jaume Morey-Canyelles Jordi Rosell Damià H Suñer Jasna Raventos-Simic Michael P Epstein Nigel M Williams Anne S Bassett

Mol Psychiatry 2020 Feb 3. Epub 2020 Feb 3.

Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/s41380-020-0654-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396297PMC
February 2020

Genetic variants in circTUBB interacting with smoking can enhance colorectal cancer risk.

Arch Toxicol 2020 01 3;94(1):325-333. Epub 2019 Dec 3.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, People's Republic of China.

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http://dx.doi.org/10.1007/s00204-019-02624-1DOI Listing
January 2020

Case report: whole genome sequencing based investigation of maternal-neonatal listeriosis in Sichuan, China.

BMC Infect Dis 2019 Oct 26;19(1):893. Epub 2019 Oct 26.

State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.

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http://dx.doi.org/10.1186/s12879-019-4551-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815428PMC
October 2019

Transarticular external fixation versus deltoid ligament repair in treating SER IV ankle fractures: a comparative study.

BMC Musculoskelet Disord 2019 Oct 18;20(1):453. Epub 2019 Oct 18.

Department of Orthopedics, West China Hospital, Sichuan University, 37# Wainan Guoxue Road, Chengdu, 610041, People's Republic of China.

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http://dx.doi.org/10.1186/s12891-019-2840-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800498PMC
October 2019

Genetic variants in m6A modification genes are associated with colorectal cancer risk.

Carcinogenesis 2020 03;41(1):8-17

Department of Environmental Genomics, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1093/carcin/bgz165DOI Listing
March 2020

Mobilization of Transplanted Bone Marrow Mesenchymal Stem Cells by Erythropoietin Facilitates the Reconstruction of Segmental Bone Defect.

Stem Cells Int 2019 1;2019:5750967. Epub 2019 Apr 1.

Department of Orthopedics, West China Hospital, Sichuan University, 37# Wainan Guoxue Road, Chengdu 610041, China.

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http://dx.doi.org/10.1155/2019/5750967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466852PMC
April 2019

A genetic variation in the CpG island of pseudogene GBAP1 promoter is associated with gastric cancer susceptibility.

Cancer 2019 07 5;125(14):2465-2473. Epub 2019 Apr 5.

Department of Environmental Genomics, Center for Global Health, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1002/cncr.32081DOI Listing
July 2019

Genetic variants in RPA1 associated with the response to oxaliplatin-based chemotherapy in colorectal cancer.

J Gastroenterol 2019 Nov 28;54(11):939-949. Epub 2019 Mar 28.

Department of Environmental Genomics, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1007/s00535-019-01571-zDOI Listing
November 2019

Combinations of single nucleotide polymorphisms identified in genome-wide association studies determine risk for colorectal cancer.

Int J Cancer 2019 11 26;145(10):2661-2669. Epub 2019 Mar 26.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, 211166, China.

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http://doi.wiley.com/10.1002/ijc.32267
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http://dx.doi.org/10.1002/ijc.32267DOI Listing
November 2019

The effects of particulate matters on allergic rhinitis in Nanjing, China.

Environ Sci Pollut Res Int 2019 Apr 25;26(11):11452-11457. Epub 2019 Feb 25.

Department of Otorhinolaryngology, First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.

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http://dx.doi.org/10.1007/s11356-019-04593-5DOI Listing
April 2019

Ambient fine particulate matter (PM) induces oxidative stress and pro-inflammatory response via up-regulating the expression of CYP1A1/1B1 in human bronchial epithelial cells in vitro.

Mutat Res Genet Toxicol Environ Mutagen 2019 Mar 12;839:40-48. Epub 2018 Dec 12.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing, China; Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.mrgentox.2018.12.005DOI Listing
March 2019

Long non-coding RNA FLJ22763 is involved in the progression and prognosis of gastric cancer.

Gene 2019 Apr 1;693:84-91. Epub 2019 Feb 1.

Department of Environmental Genomics, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China; Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2019.01.028DOI Listing
April 2019

Comparison of the modified Heuter approach and the Kocher-Langenbeck approach in the treatment of Pipkin type I and type II femoral head fractures.

Int Orthop 2019 11 25;43(11):2613-2620. Epub 2019 Jan 25.

Department of Orthopedics, West China Hospital, Sichuan University, 37# Wainan Guoxue Road, Chengdu, 610041, People's Republic of China.

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http://link.springer.com/10.1007/s00264-019-04301-5
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http://dx.doi.org/10.1007/s00264-019-04301-5DOI Listing
November 2019

Genome-wide long non-coding RNAs identified a panel of novel plasma biomarkers for gastric cancer diagnosis.

Gastric Cancer 2019 07 2;22(4):731-741. Epub 2019 Jan 2.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://link.springer.com/10.1007/s10120-018-00915-7
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http://dx.doi.org/10.1007/s10120-018-00915-7DOI Listing
July 2019

Genetic variant in miR-21 binding sites is associated with colorectal cancer risk.

J Cell Mol Med 2019 03 19;23(3):2012-2019. Epub 2018 Dec 19.

Department of Colorectal Surgery, The Third Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.

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http://doi.wiley.com/10.1111/jcmm.14104
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http://dx.doi.org/10.1111/jcmm.14104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378227PMC
March 2019

Illustration and application of enhancing effect of arginine on interactions between nano-clays: self-healing hydrogels.

Soft Matter 2019 Jan;15(2):303-311

State Key Laboratory of Organic-Inorganic Composite Materials, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Chaoyang District, Beijing, 100029, China.

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http://dx.doi.org/10.1039/c8sm02188kDOI Listing
January 2019

Polymorphism rs4787951 in IL-4R contributes to the increased risk of renal cell carcinoma in a Chinese population.

Gene 2019 Feb 23;685:242-247. Epub 2018 Nov 23.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China; State Key Laboratory of Reproductive Medicine, Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03781119183121
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http://dx.doi.org/10.1016/j.gene.2018.11.070DOI Listing
February 2019

A genome-scale metabolic network alignment method within a hypergraph-based framework using a rotational tensor-vector product.

Sci Rep 2018 11 6;8(1):16376. Epub 2018 Nov 6.

Key Laboratory of Information and Computing Science Guizhou Province, Guizhou Normal University, Guiyang, Guizhou, China.

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http://www.nature.com/articles/s41598-018-34692-1
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http://dx.doi.org/10.1038/s41598-018-34692-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219566PMC
November 2018

Exosome-transmitted long non-coding RNA PTENP1 suppresses bladder cancer progression.

Mol Cancer 2018 10 3;17(1):143. Epub 2018 Oct 3.

Department of Environmental Genomics, School of Public Health, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, China.

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https://molecular-cancer.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s12943-018-0880-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169076PMC
October 2018

Evaluation of GWAS-Identified Genetic Variants for Gastric Cancer Survival.

EBioMedicine 2018 Jul 6;33:82-87. Epub 2018 Jul 6.

Department of Oncology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.06.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085567PMC
July 2018

A genetic variant located in the miR-532-5p-binding site of TGFBR1 is associated with the colorectal cancer risk.

J Gastroenterol 2019 Feb 3;54(2):141-148. Epub 2018 Jul 3.

Department of Oncology, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing, 210006, China.

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http://dx.doi.org/10.1007/s00535-018-1490-yDOI Listing
February 2019

Multi-center evaluation of GenoType MTBDRsl line probe assay for rapid detection of pre-XDR and XDR Mycobacterium tuberculosis in China.

J Infect 2018 10 30;77(4):328-334. Epub 2018 Jun 30.

Department of Epidemiology, School of Public Health, China and Key Laboratory of Public Health Safety (Fudan University), Ministry of Education, Fudan University, Shanghai 200032, China; Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jinf.2018.06.014DOI Listing
October 2018

Circadian clock pathway genes associated with colorectal cancer risk and prognosis.

Arch Toxicol 2018 08 2;92(8):2681-2689. Epub 2018 Jul 2.

Department of Oncology, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing, 210000, Jiangsu, People's Republic of China.

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http://dx.doi.org/10.1007/s00204-018-2251-7DOI Listing
August 2018

Evaluating the effect of multiple genetic risk score models on colorectal cancer risk prediction.

Gene 2018 Oct 14;673:174-180. Epub 2018 Jun 14.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China; Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China; China International Cooperation Center for Environment and Human Health, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2018.06.035DOI Listing
October 2018

Effects of Natural Hirudin and Low Molecular Weight Heparin in Preventing Deep Venous Thrombosis in Aged Patients with Intertrochanteric Fracture.

Sci Rep 2018 06 11;8(1):8847. Epub 2018 Jun 11.

Department of Othopedics, West China Hospital, Sichuan University, 37# Wainan Guoxue Road, Chendu, 610041, People's Republic of China.

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http://dx.doi.org/10.1038/s41598-018-27243-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995864PMC
June 2018

Body mass index (BMI) trajectories and risk of colorectal cancer in the PLCO cohort.

Br J Cancer 2018 07 6;119(1):130-132. Epub 2018 Jun 6.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1038/s41416-018-0121-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035226PMC
July 2018

Genetic variants in PI3K/Akt/mTOR pathway genes contribute to gastric cancer risk.

Gene 2018 Sep 24;670:130-135. Epub 2018 May 24.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China; Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03781119183059
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http://dx.doi.org/10.1016/j.gene.2018.05.093DOI Listing
September 2018

Association study of genetic variants in estrogen metabolic pathway genes and colorectal cancer risk and survival.

Arch Toxicol 2018 06 16;92(6):1991-1999. Epub 2018 May 16.

Department of Oncology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, Jiangsu, People's Republic of China.

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http://dx.doi.org/10.1007/s00204-018-2195-yDOI Listing
June 2018

Vitamin B intake reduces the risk for colorectal cancer: a dose-response analysis.

Eur J Nutr 2019 Jun 9;58(4):1591-1602. Epub 2018 May 9.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1007/s00394-018-1702-5DOI Listing
June 2019

LncRNA and its genetic variant rs1902432 are associated with prostate cancer risk.

J Cancer 2018 6;9(8):1414-1420. Epub 2018 Apr 6.

Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.7150/jca.23685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929086PMC
April 2018

LncRNA MT1JP functions as a ceRNA in regulating FBXW7 through competitively binding to miR-92a-3p in gastric cancer.

Mol Cancer 2018 05 2;17(1):87. Epub 2018 May 2.

Department of Environmental Genomics, School of Public Health, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, China.

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https://molecular-cancer.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s12943-018-0829-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930724PMC
May 2018

A Genetic Variant Located in Promoter Region Is Associated with Prognosis of Gastric Cancer.

Cancer Epidemiol Biomarkers Prev 2018 07 23;27(7):822-828. Epub 2018 Apr 23.

Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1158/1055-9965.EPI-17-1054DOI Listing
July 2018

Tagging SNPs in the HOTAIR gene are associated with bladder cancer risk in a Chinese population.

Gene 2018 Jul 16;664:22-26. Epub 2018 Apr 16.

Department of General Surgery, Yixing Tumor Hospital, Yixing, China. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2018.04.039DOI Listing
July 2018

Epigenetic alterations to Polycomb targets precede malignant transition in a mouse model of breast cancer.

Sci Rep 2018 04 3;8(1):5535. Epub 2018 Apr 3.

Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, USA.

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http://dx.doi.org/10.1038/s41598-018-24005-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882905PMC
April 2018

Genetic variants in XDH are associated with prognosis for gastric cancer in a Chinese population.

Gene 2018 Jul 15;663:196-202. Epub 2018 Mar 15.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China; Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2018.03.043DOI Listing
July 2018

Polymorphism rs2682818 in miR-618 is associated with colorectal cancer susceptibility in a Han Chinese population.

Cancer Med 2018 04 13;7(4):1194-1200. Epub 2018 Mar 13.

Department of Oncology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1002/cam4.1409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911622PMC
April 2018

Multidrug-Resistant : Co-occurrence of β-Lactamase and MCR-1 Encoding Genes.

Front Microbiol 2018 16;9:258. Epub 2018 Feb 16.

Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

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http://dx.doi.org/10.3389/fmicb.2018.00258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820351PMC
February 2018

Evaluation of vulnerable PM-exposure individuals: a repeated-measure study in an elderly population.

Environ Sci Pollut Res Int 2018 Apr 14;25(12):11833-11840. Epub 2018 Feb 14.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Nanjing, 211166, China.

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http://dx.doi.org/10.1007/s11356-018-1412-9DOI Listing
April 2018

Association between obesity and bladder cancer recurrence: A meta-analysis.

Clin Chim Acta 2018 May 20;480:41-46. Epub 2018 Feb 20.

Department of Environmental Genomics, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China; Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2018.01.039DOI Listing
May 2018

Prevalence and molecular characteristics of Listeria monocytogenes in cooked products and its comparison with isolates from listeriosis cases.

Front Med 2018 Feb 25;12(1):104-112. Epub 2018 Jan 25.

State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.

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http://dx.doi.org/10.1007/s11684-017-0593-9DOI Listing
February 2018

Hypermethylation of EIF4E promoter is associated with early onset of gastric cancer.

Carcinogenesis 2018 01;39(1):66-71

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1093/carcin/bgx110DOI Listing
January 2018

PGA: post-GWAS analysis for disease gene identification.

Bioinformatics 2018 05;34(10):1786-1788

Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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https://academic.oup.com/bioinformatics/article/34/10/1786/4
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http://dx.doi.org/10.1093/bioinformatics/btx845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946835PMC
May 2018

Integrated rare variant-based risk gene prioritization in disease case-control sequencing studies.

PLoS Genet 2017 12 27;13(12):e1007142. Epub 2017 Dec 27.

Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760082PMC
December 2017

A functional polymorphism in TFF1 promoter is associated with the risk and prognosis of gastric cancer.

Int J Cancer 2018 05 20;142(9):1805-1816. Epub 2017 Dec 20.

Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1002/ijc.31197DOI Listing
May 2018

Ilizarov external fixation versus plate internal fixation in the treatment of end-stage ankle arthritis: decision analysis of clinical parameters.

Sci Rep 2017 11 23;7(1):16155. Epub 2017 Nov 23.

Department of Orthopedics, West China Hospital, Sichuan University, 37# Wainan Guoxue Road, Chengdu, 610041, People's Republic of China.

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http://dx.doi.org/10.1038/s41598-017-16473-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701001PMC
November 2017

XRCC1 mediated the development of cervival cancer through a novel Sp1/Krox-20 swich.

Oncotarget 2017 Oct 16;8(49):86217-86226. Epub 2017 Sep 16.

Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China.

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http://dx.doi.org/10.18632/oncotarget.21040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689679PMC
October 2017

HEDD: Human Enhancer Disease Database.

Nucleic Acids Res 2018 01;46(D1):D113-D120

Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://academic.oup.com/nar/article/46/D1/D113/4564801
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http://dx.doi.org/10.1093/nar/gkx988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753236PMC
January 2018

Defining the Genetic Features of O-Antigen Biosynthesis Gene Cluster and Performance of an O-Antigen Serotyping Scheme for .

Front Microbiol 2017 26;8:1857. Epub 2017 Sep 26.

State Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

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http://dx.doi.org/10.3389/fmicb.2017.01857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622975PMC
September 2017

Information transduction capacity reduces the uncertainties in annotation-free isoform discovery and quantification.

Nucleic Acids Res 2017 Sep;45(15):e143

Department of Automation, Tsinghua National Laboratory for Information Science and Technology, Tsinghua University, Beijing 100084, P. R. China.

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http://dx.doi.org/10.1093/nar/gkx585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587798PMC
September 2017

Linkage between human population and trace elements in soils of the Pearl River Delta: Implications for source identification and risk assessment.

Sci Total Environ 2018 Jan 19;610-611:944-950. Epub 2017 Aug 19.

State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China. Electronic address:

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http://dx.doi.org/10.1016/j.scitotenv.2017.08.147DOI Listing
January 2018

Translation fidelity coevolves with longevity.

Aging Cell 2017 10 13;16(5):988-993. Epub 2017 Jul 13.

Department of Biology, University of Rochester, Rochester, NY, USA.

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http://dx.doi.org/10.1111/acel.12628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595694PMC
October 2017

Short-term effects of ambient air pollution and childhood lower respiratory diseases.

Sci Rep 2017 06 30;7(1):4414. Epub 2017 Jun 30.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1038/s41598-017-04310-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493680PMC
June 2017

Plasma Mesothelin as a Novel Diagnostic and Prognostic Biomarker in Colorectal Cancer.

J Cancer 2017 12;8(8):1355-1361. Epub 2017 May 12.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.7150/jca.18014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479240PMC
May 2017

The association of rs710886 in lncRNA PCAT1 with bladder cancer risk in a Chinese population.

Gene 2017 Sep 13;627:226-232. Epub 2017 Jun 13.

Department of Environmental Genomics, Nanjing Medical University, Nanjing, China; Department of Genetic Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2017.06.021DOI Listing
September 2017

HOTAIR rs7958904 polymorphism is associated with increased cervical cancer risk in a Chinese population.

Sci Rep 2017 06 9;7(1):3144. Epub 2017 Jun 9.

Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China.

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http://dx.doi.org/10.1038/s41598-017-03174-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466640PMC
June 2017

Mxd1 mediates hypoxia-induced cisplatin resistance in osteosarcoma cells by repression of the PTEN tumor suppressor gene.

Mol Carcinog 2017 10 15;56(10):2234-2244. Epub 2017 Jun 15.

Clinical Molecular Diagnostic Laboratory, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, P. R. China.

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http://dx.doi.org/10.1002/mc.22676DOI Listing
October 2017

An inverse association between tea consumption and colorectal cancer risk.

Oncotarget 2017 Jun;8(23):37367-37376

Department of Oncology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.18632/oncotarget.16959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514915PMC
June 2017

Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis.

Bone Res 2017 21;5:17008. Epub 2017 Mar 21.

Department of Orthopaedic Surgery, Institute for Cell Engineering, Johns Hopkins University , Baltimore, MD, USA.

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http://dx.doi.org/10.1038/boneres.2017.8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360159PMC
March 2017

Exome Array Analysis Identifies Variants in SPOCD1 and BTN3A2 That Affect Risk for Gastric Cancer.

Gastroenterology 2017 06 27;152(8):2011-2021. Epub 2017 Feb 27.

Department of Epidemiology and Biostatistics, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Medicine, School of Public Health, Nanjing Medical University, Nanjing, China; State Key Laboratory of Reproductive Medicine, International Joint Research Center for Environment and Human Health, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.02.017DOI Listing
June 2017

KCNMA1 cooperating with PTK2 is a novel tumor suppressor in gastric cancer and is associated with disease outcome.

Mol Cancer 2017 02 23;16(1):46. Epub 2017 Feb 23.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Cancer Center, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1186/s12943-017-0613-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324255PMC
February 2017

Transcriptomic dynamics of breast cancer progression in the MMTV-PyMT mouse model.

BMC Genomics 2017 02 17;18(1):185. Epub 2017 Feb 17.

Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://dx.doi.org/10.1186/s12864-017-3563-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316186PMC
February 2017

Probabilistic natural mapping of gene-level tests for genome-wide association studies.

Brief Bioinform 2018 07;19(4):545-553

Department of Automation, Tsinghua University, China.

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http://dx.doi.org/10.1093/bib/bbx002DOI Listing
July 2018

Genetic variants, PM exposure level and global DNA methylation level: A multi-center population-based study in Chinese.

Toxicol Lett 2017 Mar 6;269:77-82. Epub 2017 Feb 6.

Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Medicine, Nanjing Medical University, Nanjing, Jiangsu, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03784274173005
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http://dx.doi.org/10.1016/j.toxlet.2017.02.003DOI Listing
March 2017

Evaluation of genome-wide genotyping concordance between tumor tissues and peripheral blood.

Genomics 2017 03 2;109(2):108-112. Epub 2017 Feb 2.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China; Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2017.01.003DOI Listing
March 2017

The HOTAIR, PRNCR1 and POLR2E polymorphisms are associated with cancer risk: a meta-analysis.

Oncotarget 2017 Jun;8(26):43271-43283

Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China.

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http://www.oncotarget.com/fulltext/14920
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http://dx.doi.org/10.18632/oncotarget.14920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522144PMC
June 2017

Impact of genotypic and phenotypic resistance to second-line anti-tuberculosis drugs on treatment outcomes in multidrug-resistant tuberculosis in China.

Int J Mycobacteriol 2016 Dec 22;5 Suppl 1:S34-S35. Epub 2016 Nov 22.

Department of Microbiology, Tumor and Cell biology (MTC), Karolinska Institutet, Solna, Sweden.

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http://dx.doi.org/10.1016/j.ijmyco.2016.11.007DOI Listing
December 2016

pncA mutations are associated with slower sputum conversion during standard treatment of multidrug-resistant tuberculosis.

Int J Antimicrob Agents 2017 Feb 24;49(2):183-188. Epub 2016 Nov 24.

Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China; Ministry of Education, Key Laboratory of Public Health Safety (Fudan University), China. Electronic address:

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http://dx.doi.org/10.1016/j.ijantimicag.2016.10.012DOI Listing
February 2017

Genetic variation in IGF1 predicts renal cell carcinoma susceptibility and prognosis in Chinese population.

Sci Rep 2016 12 15;6:39014. Epub 2016 Dec 15.

Department of Urology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.

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http://dx.doi.org/10.1038/srep39014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157037PMC
December 2016

miR-107 regulates tumor progression by targeting NF1 in gastric cancer.

Sci Rep 2016 11 9;6:36531. Epub 2016 Nov 9.

Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1038/srep36531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101511PMC
November 2016