Dr. Zhenbang Chen, Ph.D. - Meharry Medical College - Associate Professor

Dr. Zhenbang Chen

Ph.D.

Meharry Medical College

Associate Professor

Nashville, TN | United States

Main Specialties: Oncology

Additional Specialties: PTEN-AKT, Prostate Cancer

Dr. Zhenbang Chen, Ph.D. - Meharry Medical College - Associate Professor

Dr. Zhenbang Chen

Ph.D.

Introduction

Primary Affiliation: Meharry Medical College - Nashville, TN , United States

Specialties:

Additional Specialties:

Publications

39Publications

1289Reads

9Profile Views

2605PubMed Central Citations

Nuclear MET requires ARF and is inhibited by carbon nanodots through binding to phospho-tyrosine in prostate cancer.

Oncogene 2019 04 19;38(16):2967-2983. Epub 2018 Dec 19.

Department of Chemistry, Nazarbayev University School of Science and Technology, Astana, 010000, Kazakhstan.

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http://dx.doi.org/10.1038/s41388-018-0608-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474787PMC
April 2019
6 Reads
8.459 Impact Factor

Interleukin-17 promotes metastasis in an immunocompetent orthotopic mouse model of prostate cancer.

Am J Clin Exp Urol 2018 15;6(3):114-122. Epub 2018 Jun 15.

Department of Structural and Cellular Biology, Tulane University New Orleans 70112, Louisiana.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055074PMC
June 2018
11 Reads

Translocator Protein PET Imaging in a Preclinical Prostate Cancer Model.

Mol Imaging Biol 2018 04;20(2):200-204

Imaging Research, Barrow Neurological Institute, 350 W Thomas Rd, Phoenix, AZ, 85013, USA.

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http://dx.doi.org/10.1007/s11307-017-1113-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903879PMC
April 2018
11 Reads
2 Citations
2.774 Impact Factor

SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway.

Nat Commun 2018 01 9;9(1):101. Epub 2018 Jan 9.

Chromatin Biology Laboratory, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Av. Gran Via de l'Hospitalet 199-203, 08908, L'Hospitalet de Llobregat (Barcelona), Spain.

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http://dx.doi.org/10.1038/s41467-017-02586-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760577PMC
January 2018
76 Reads
1 Citation
10.742 Impact Factor

Dysregulation of YAP by ARF Stimulated with Tea-derived Carbon Nanodots.

Sci Rep 2017 11 29;7(1):16577. Epub 2017 Nov 29.

Department of Chemistry, School of Science and Technology, Nazarbayev University, Astana, 010000, Kazakhstan.

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http://dx.doi.org/10.1038/s41598-017-16441-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707370PMC
November 2017
11 Reads
5.080 Impact Factor

SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer.

Oncogene 2017 03 21;36(10):1364-1373. Epub 2016 Nov 21.

Department of Biochemistry and Cancer Biology, Meharry Medical College, Nashville, TN, USA.

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http://dx.doi.org/10.1038/onc.2016.300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724960PMC
March 2017
20 Reads
5 Citations
8.460 Impact Factor

Analysis of origin and protein-protein interaction maps suggests distinct oncogenic role of nuclear EGFR during cancer evolution.

J Cancer 2017 12;8(5):903-912. Epub 2017 Mar 12.

Department of Biology, School of Science and Technology, Nazarbayev University, Astana, 010000, Republic of Kazakhstan.

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http://dx.doi.org/10.7150/jca.17961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381180PMC
March 2017
30 Reads
2.640 Impact Factor

Fetuin-A (alpha 2HS glycoprotein) modulates growth, motility, invasion, and senescence in high-grade astrocytomas.

Cancer Med 2016 12 23;5(12):3532-3543. Epub 2016 Nov 23.

Department of Biochemistry and Cancer Biology, Meharry Medical College, 1005 D.B. Todd Blvd., Nashville, 37208, Tennessee.

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http://dx.doi.org/10.1002/cam4.940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224863PMC
December 2016
41 Reads
3 Citations

MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo.

Oncotarget 2016 Jul;7(30):47609-47619

Department of Biochemistry and Cancer Biology, Meharry Medical College, Nashville, TN, 37208, USA.

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http://dx.doi.org/10.18632/oncotarget.10251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216965PMC
July 2016
22 Reads
4 Citations
6.360 Impact Factor

The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis.

Carcinogenesis 2015 Jun;36 Suppl 1:S128-59

Department of Biochemistry and Cancer Biology, Meharry Medical College, Nashville, TN 37208, USA, Department of Environmental and Occupational Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA, Department of Biology/Center for Cancer Research and Therapeutic Development, Clark Atlanta University, Atlanta, GA 30314, USA, Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA, Department of Pathology, Wayne State University, Detroit, MI 48201, USA, Department of Obstetrics and Gynecology, University of Melbourne, Melbourne, Victoria, Australia, Faculty of Pharmacy, Department of Pathology, Kuwait University, Safat 13110, Kuwait, Department of Otolaryngology, University of Michigan Medical College, Ann Arbor, MI 48109, USA, Department of Molecular & Cellular Biochemistry, University of Kentucky, Lexington, KY 40506, USA, Department of Environmental and Radiological Health Sciences/Food Science and Human Nutrition, College of Veterinary Medicine and Biomedical Sciences, Colorado State University/Colorado School of Public Health, Fort Collins, CO 80523-1680, USA, Center for Environmental Carcinogenesis and Risk Assessment, Environmental Protection and Health Prevention Agency, Bologna 40126, Italy, Faculty of Medicine and Health Sciences, University Putra, Serdang, Selangor 43400, Malaysia, Istituto di Genetica Molecolare, CNR, via Abbiategrasso 207, 27100 Pavia, Italy, Toxicology Research Division, Bureau of Chemical Safety Food Directorate, Health Products and Food Branch Health Canada, Ottawa, Ontario K1A0K9, Canada, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA, Centre for Advanced Research, King George's Medical University, Chowk, Lucknow, Uttar Pradesh 226003, India, Mediterranean Institute of Oncology, Viagrande 95029, Italy, Urology Department, kasr Al-Ainy School of Medicine, Cairo University, El Manial, Cairo 12515, Egypt, Department of Experimental and

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http://carcin.oxfordjournals.org/content/36/Suppl_1/S128.ful
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
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http://dx.doi.org/10.1093/carcin/bgv034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565611PMC
June 2015
51 Reads
7 Citations
5.334 Impact Factor

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Authors:
William H Goodson Leroy Lowe David O Carpenter Michael Gilbertson Abdul Manaf Ali Adela Lopez de Cerain Salsamendi Ahmed Lasfar Amancio Carnero Amaya Azqueta Amedeo Amedei Amelia K Charles Andrew R Collins Andrew Ward Anna C Salzberg Annamaria Colacci Ann-Karin Olsen Arthur Berg Barry J Barclay Binhua P Zhou Carmen Blanco-Aparicio Carolyn J Baglole Chenfang Dong Chiara Mondello Chia-Wen Hsu Christian C Naus Clement Yedjou Colleen S Curran Dale W Laird Daniel C Koch Danielle J Carlin Dean W Felsher Debasish Roy Dustin G Brown Edward Ratovitski Elizabeth P Ryan Emanuela Corsini Emilio Rojas Eun-Yi Moon Ezio Laconi Fabio Marongiu Fahd Al-Mulla Ferdinando Chiaradonna Firouz Darroudi Francis L Martin Frederik J Van Schooten Gary S Goldberg Gerard Wagemaker Gladys N Nangami Gloria M Calaf Graeme Williams Gregory T Wolf Gudrun Koppen Gunnar Brunborg H Kim Lyerly Harini Krishnan Hasiah Ab Hamid Hemad Yasaei Hideko Sone Hiroshi Kondoh Hosni K Salem Hsue-Yin Hsu Hyun Ho Park Igor Koturbash Isabelle R Miousse A Ivana Scovassi James E Klaunig Jan Vondráček Jayadev Raju Jesse Roman John Pierce Wise Jonathan R Whitfield Jordan Woodrick Joseph A Christopher Josiah Ochieng Juan Fernando Martinez-Leal Judith Weisz Julia Kravchenko Jun Sun Kalan R Prudhomme Kannan Badri Narayanan Karine A Cohen-Solal Kim Moorwood Laetitia Gonzalez Laura Soucek Le Jian Leandro S D'Abronzo Liang-Tzung Lin Lin Li Linda Gulliver Lisa J McCawley Lorenzo Memeo Louis Vermeulen Luc Leyns Luoping Zhang Mahara Valverde Mahin Khatami Maria Fiammetta Romano Marion Chapellier Marc A Williams Mark Wade Masoud H Manjili Matilde E Lleonart Menghang Xia Michael J Gonzalez Michalis V Karamouzis Micheline Kirsch-Volders Monica Vaccari Nancy B Kuemmerle Neetu Singh Nichola Cruickshanks Nicole Kleinstreuer Nik van Larebeke Nuzhat Ahmed Olugbemiga Ogunkua P K Krishnakumar Pankaj Vadgama Paola A Marignani Paramita M Ghosh Patricia Ostrosky-Wegman Patricia A Thompson Paul Dent Petr Heneberg Philippa Darbre Po Sing Leung Pratima Nangia-Makker Qiang Shawn Cheng R Brooks Robey Rabeah Al-Temaimi Rabindra Roy Rafaela Andrade-Vieira Ranjeet K Sinha Rekha Mehta Renza Vento Riccardo Di Fiore Richard Ponce-Cusi Rita Dornetshuber-Fleiss Rita Nahta Robert C Castellino Roberta Palorini Roslida Abd Hamid Sabine A S Langie Sakina E Eltom Samira A Brooks Sandra Ryeom Sandra S Wise Sarah N Bay Shelley A Harris Silvana Papagerakis Simona Romano Sofia Pavanello Staffan Eriksson Stefano Forte Stephanie C Casey Sudjit Luanpitpong Tae-Jin Lee Takemi Otsuki Tao Chen Thierry Massfelder Thomas Sanderson Tiziana Guarnieri Tove Hultman Valérian Dormoy Valerie Odero-Marah Venkata Sabbisetti Veronique Maguer-Satta W Kimryn Rathmell Wilhelm Engström William K Decker William H Bisson Yon Rojanasakul Yunus Luqmani Zhenbang Chen Zhiwei Hu

Carcinogenesis 2015 Jun;36 Suppl 1:S254-96

Department of Surgery, The Ohio State University College of Medicine, The James Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
Web Search
http://www.ilcambiamento.it/files/carcinogenesi.pdf
Web Search
http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
Publisher Site
http://dx.doi.org/10.1093/carcin/bgv039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480130PMC
June 2015
239 Reads
38 Citations
5.334 Impact Factor

Roles of ubiquitination and SUMOylation on prostate cancer: mechanisms and clinical implications.

Int J Mol Sci 2015 Feb 27;16(3):4560-80. Epub 2015 Feb 27.

Department of Biochemistry and Cancer Biology, Meharry Medical College, Nashville, TN 37208, USA.

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http://dx.doi.org/10.3390/ijms16034560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394435PMC
February 2015
6 Reads
10 Citations
2.862 Impact Factor

Identifying actionable targets through integrative analyses of GEM model and human prostate cancer genomic profiling.

Mol Cancer Ther 2015 Jan 7;14(1):278-88. Epub 2014 Nov 7.

Human Oncology and Pathogenesis Oncology Program, Memorial Sloan-Kettering Cancer Center, New York, New York. Department of Surgery and Division of Urology, Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://mct.aacrjournals.org/content/14/1/278.full.pdf
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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-14
Publisher Site
http://dx.doi.org/10.1158/1535-7163.MCT-14-0542-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297258PMC
January 2015
40 Reads
13 Citations
5.683 Impact Factor

SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination.

Oncotarget 2015 Jan;6(2):771-88

Department of Biochemistry and Cancer Biology, Meharry Medical College, TN 37208, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359254PMC
http://dx.doi.org/10.18632/oncotarget.2718DOI Listing
January 2015
40 Reads
20 Citations
6.360 Impact Factor

Crosstalk between nuclear MET and SOX9/β-catenin correlates with castration-resistant prostate cancer.

Mol Endocrinol 2014 Oct 6;28(10):1629-39. Epub 2014 Aug 6.

Department of Biochemistry and Cancer Biology (Y.X., W.L., S.L., Q.Y., Z.C.), Meharry Medical College, Nashville, Tennessee 37208; Department of Surgery and Division of Urology (B.S.C.), Memorial Sloan-Kettering Cancer Center, New York, New York 10065; and Vancouver Prostate Centre and Department of Urologic Sciences (E.L., Y.W., L.F., M.G.), The University of British Columbia, Vancouver, British Columbia, Canada V6H 3Z6.

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http://dx.doi.org/10.1210/me.2014-1078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179634PMC
October 2014
24 Reads
10 Citations
4.022 Impact Factor

Slug regulates E-cadherin repression via p19Arf in prostate tumorigenesis.

Mol Oncol 2014 Oct 21;8(7):1355-64. Epub 2014 May 21.

Department of Biochemistry and Cancer Biology, Meharry Medical College, 1005 Dr. D. B. Todd Jr. Blvd, Nashville, TN 37208, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2014.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198473PMC
October 2014
61 Reads
17 Citations
5.331 Impact Factor

Mouse models of prostate cancer: picking the best model for the question.

Cancer Metastasis Rev 2014 Sep;33(2-3):377-97

Vanderbilt University, Nashville, TN, USA,

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http://dx.doi.org/10.1007/s10555-013-9487-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108581PMC
September 2014
47 Reads
21 Citations
7.234 Impact Factor

Skp2 regulates androgen receptor through ubiquitin-mediated degradation independent of Akt/mTOR pathways in prostate cancer.

Prostate 2014 Apr 17;74(4):421-32. Epub 2013 Dec 17.

Department of Biochemistry and Cancer Biology, Meharry Medical College, Nashville, Tennessee.

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http://dx.doi.org/10.1002/pros.22763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062570PMC
April 2014
19 Reads
13 Citations
3.565 Impact Factor

Regulation of Androgen Receptor by E3 Ubiquitin Ligases: for More or Less.

Receptors Clin Investig 2014 ;1(5)

Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, 1005 Dr. D.B. Todd Jr. Boulevard, Nashville, Tennessee 37208-3599, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139040PMC
http://dx.doi.org/10.14800/rci.122DOI Listing
January 2014
37 Reads
9 Citations

Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion.

Nat Genet 2013 Jul 2;45(7):739-746. Epub 2013 Jun 2.

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Departments of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1038/ng.2654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036521PMC
July 2013
75 Reads
40 Citations
29.352 Impact Factor

ARF represses androgen receptor transactivation in prostate cancer.

Mol Endocrinol 2013 Apr 28;27(4):635-48. Epub 2013 Feb 28.

Department of Biochemistry and Cancer Biology, Meharry Medical College, 1005 Dr D. B. Todd Jr Boulevard, Nashville, Tennessee 37208, USA.

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http://dx.doi.org/10.1210/me.2012-1294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607697PMC
April 2013
11 Reads
13 Citations
4.022 Impact Factor

XMRV accelerates cellular proliferation, transformational activity, and invasiveness of prostate cancer cells by downregulating p27(Kip1).

Prostate 2012 Jun 19;72(8):886-97. Epub 2011 Sep 19.

Laboratory of Retrovirology and Epigenetics, Center for AIDS Health Disparities Research, Vanderbilt-Meharry Center For AIDS Research (CFAR), Meharry Medical College School of Medicine, 1005 Dr. DB Todd Jr Blvd., Nashville, TN 37208, USA.

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http://dx.doi.org/10.1002/pros.21491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275676PMC
June 2012
8 Reads
9 Citations
3.565 Impact Factor

Interleukin-17 promotes formation and growth of prostate adenocarcinoma in mouse models.

Cancer Res 2012 May 28;72(10):2589-99. Epub 2012 Mar 28.

Department of Structural & Cellular Biology, School of Medicine, New Orleans, LA, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665158PMC
May 2012
48 Reads
37 Citations
9.330 Impact Factor

A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.

J Clin Invest 2010 Mar 8;120(3):681-93. Epub 2010 Feb 8.

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Departments of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1172/JCI40535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827955PMC
March 2010
17 Reads
113 Citations
13.215 Impact Factor

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.

Nature 2010 Mar;464(7287):374-9

Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nature08815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928066PMC
March 2010
34 Reads
166 Citations
42.351 Impact Factor

Differential p53-independent outcomes of p19(Arf) loss in oncogenesis.

Sci Signal 2009 Aug 18;2(84):ra44. Epub 2009 Aug 18.

Beth Israel Deaconess Cancer Center, Departments of Medicine and Pathology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/scisignal.2000053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928478PMC
August 2009
7 Reads
36 Citations
6.280 Impact Factor

Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate.

Nat Genet 2009 May 26;41(5):619-24. Epub 2009 Apr 26.

Cancer Biology and Genetics Program, Sloan-Kettering Institute, New York, New York, USA.

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http://dx.doi.org/10.1038/ng.370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835150PMC
May 2009
19 Reads
232 Citations
29.352 Impact Factor

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB.

Nat Cell Biol 2009 Apr 8;11(4):420-32. Epub 2009 Mar 8.

Department of Pathology, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/ncb1849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830812PMC
April 2009
9 Reads
110 Citations
19.680 Impact Factor

ETS rearrangements and prostate cancer initiation.

Nature 2009 Feb;457(7231):E1; discussion E2-3

Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nature07738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967456PMC
February 2009
72 Reads
39 Citations
42.351 Impact Factor

Differential requirement of mTOR in postmitotic tissues and tumorigenesis.

Sci Signal 2009 Jan 27;2(55):ra2. Epub 2009 Jan 27.

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/scisignal.2000189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906144PMC
January 2009
16 Reads
25 Citations
6.280 Impact Factor

Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events.

Genes Dev 2008 Aug;22(16):2172-7

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1101/gad.1699608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518820PMC
August 2008
16 Reads
38 Citations
10.800 Impact Factor

Pennisetum squamulatum: is the predominant cytotype hexaploid or octaploid?

J Hered 2006 Sep-Oct;97(5):521-4. Epub 2006 Jun 22.

Department of Horticulture, University of Georgia Tifton Campus, Tifton, GA 31793-0748, USA.

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http://dx.doi.org/10.1093/jhered/esl005DOI Listing
January 2007
15 Reads
2 Citations
2.090 Impact Factor

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN.

Cell 2007 Jan;128(1):129-39

Cell Biology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Box 522, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.cell.2006.11.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828909PMC
January 2007
38 Reads
214 Citations
32.242 Impact Factor

Ubiquitination regulates PTEN nuclear import and tumor suppression.

Cell 2007 Jan;128(1):141-56

Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.cell.2006.11.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855245PMC
January 2007
13 Reads
232 Citations
32.242 Impact Factor

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.

Nature 2005 Aug;436(7051):725-30

Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, Sloan-Kettering Institute, 1275 York Avenue, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nature03918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939938PMC
August 2005
17 Reads
657 Citations
42.351 Impact Factor

Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression.

Genes Dev 2005 Aug 18;19(15):1779-86. Epub 2005 Jul 18.

Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1101/gad.1314405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182340PMC
August 2005
3 Reads
36 Citations
10.800 Impact Factor

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis.

Cell 2005 Apr;121(2):179-93

Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1016/j.cell.2005.02.031DOI Listing
April 2005
11 Reads
412 Citations
32.242 Impact Factor

Top co-authors

Pier Paolo Pandolfi
Pier Paolo Pandolfi

Cancer Research Institute

15
Wenfu Lu
Wenfu Lu

Cancer Institute

12
Yingqiu Xie
Yingqiu Xie

University of Maryland School of Medicine

10
Andrea Alimonti
Andrea Alimonti

Harvard Medical School

8
Qing Yang
Qing Yang

Zhejiang University

8
Brett S Carver
Brett S Carver

Louisiana State University Health Sciences Center

7
Caterina Nardella
Caterina Nardella

Beth Israel Deaconess Cancer Center

7
William Gerald
William Gerald

New York University School of Medicine

5
Arkaitz Carracedo
Arkaitz Carracedo

Harvard Medical School

5