Zhaohui Feng

Zhaohui Feng

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Zhaohui Feng

Publications by authors named "Zhaohui Feng"

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Association of KRAS mutation with tumor deposit status and overall survival of colorectal cancer.

Cancer Causes Control 2020 Jul 11;31(7):683-689. Epub 2020 May 11.

Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.

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http://dx.doi.org/10.1007/s10552-020-01313-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319095PMC
July 2020

Gain of function mutant p53 protein activates AKT through the Rac1 signaling to promote tumorigenesis.

Cell Cycle 2020 Jun 10;19(11):1338-1351. Epub 2020 Apr 10.

Rutgers Cancer Institute of New Jersey; Rutgers University , New Brunswick, NJ, USA.

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http://dx.doi.org/10.1080/15384101.2020.1749790DOI Listing
June 2020

Loss of H3K36 Methyltransferase SETD2 Impairs V(D)J Recombination during Lymphoid Development.

iScience 2020 Mar 27;23(3):100941. Epub 2020 Feb 27.

Department of Pediatric Oncology, Dana Farber Cancer Institute, and Division of Hematology/Oncology, Boston Children's Hospital, 450 Brookline Avenue, Boston, MA 02215-5450, USA. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2020.100941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066224PMC
March 2020

The role of p53 in reproduction, an unexpected function for a tumor suppressor.

J Mol Cell Biol 2019 07;11(7):624-627

Rutgers Cancer Institute of New Jersey, Rutgers University, New Brunswick, NJ 08903, USA.

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http://dx.doi.org/10.1093/jmcb/mjz072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735926PMC
July 2019

Genetic variant in the promoter region of microRNA‑137 reduces the warfarin maintenance dose in patients with atrial fibrillation.

Mol Med Rep 2019 Jun 30;19(6):5361-5367. Epub 2019 Apr 30.

Department of Cardiology, China‑Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China.

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http://dx.doi.org/10.3892/mmr.2019.10205DOI Listing
June 2019

Tumor suppressor p53 and metabolism.

J Mol Cell Biol 2019 04;11(4):284-292

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers University, State University of New Jersey, New Brunswick, NJ, USA.

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http://dx.doi.org/10.1093/jmcb/mjy070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487777PMC
April 2019

Suppression of microRNA-495 alleviates high-glucose-induced retinal ganglion cell apoptosis by regulating Notch/PTEN/Akt signaling.

Biomed Pharmacother 2018 Oct 12;106:923-929. Epub 2018 Jul 12.

Ophthalmology Department, The Second Affiliated Hospital, Medical College, Xi'an Jiaotong University, Xi'an, 710004, PR China.

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http://dx.doi.org/10.1016/j.biopha.2018.07.018DOI Listing
October 2018

Parkinson's disease-associated protein Parkin: an unusual player in cancer.

Cancer Commun (Lond) 2018 06 26;38(1):40. Epub 2018 Jun 26.

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, NJ, 08903, USA.

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http://dx.doi.org/10.1186/s40880-018-0314-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020249PMC
June 2018

A polymorphism in the tumor suppressor p53 affects aging and longevity in mouse models.

Elife 2018 03 20;7. Epub 2018 Mar 20.

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers, the State University of New Jersey, New Brunswick, United States.

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http://dx.doi.org/10.7554/eLife.34701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906094PMC
March 2018

A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response.

Cell 2018 02;172(5):1007-1021.e17

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02210, USA; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.01.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052445PMC
February 2018

Mercury risk in poultry in the Wanshan Mercury Mine, China.

Environ Pollut 2017 Nov 10;230:810-816. Epub 2017 Aug 10.

State Key Laboratory of Environmental Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550081, China.

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http://dx.doi.org/10.1016/j.envpol.2017.07.027DOI Listing
November 2017

Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression.

Nat Commun 2017 11 28;8(1):1823. Epub 2017 Nov 28.

Rutgers Cancer Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers, State University of New Jersey, New Brunswick, NJ, 08903, USA.

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http://dx.doi.org/10.1038/s41467-017-01947-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703960PMC
November 2017

Gain-of-function mutant p53 activates small GTPase Rac1 through SUMOylation to promote tumor progression.

Genes Dev 2017 08;31(16):1641-1654

Rutgers Cancer Institute of New Jersey, the State University of New Jersey, New Brunswick, New Jersey 08903, USA.

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http://dx.doi.org/10.1101/gad.301564.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647935PMC
August 2017

Mutant p53 in Cancer: Accumulation, Gain-of-Function, and Therapy.

J Mol Biol 2017 06 6;429(11):1595-1606. Epub 2017 Apr 6.

Rutgers Cancer Institute of New Jersey, Rutgers, the State University of New Jersey, New Brunswick, NJ 08903, USA; Department of Pharmacology, Rutgers, the State University of New Jersey, New Brunswick, NJ 08903, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2017.03.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663274PMC
June 2017

MicroRNA Control of p53.

J Cell Biochem 2017 01 3;118(1):7-14. Epub 2016 Jun 3.

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick 08903, New Jersey.

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http://dx.doi.org/10.1002/jcb.25609DOI Listing
January 2017

A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis.

Cell Discov 2016 1;2:16039. Epub 2016 Nov 1.

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers the State University of New Jersey, New Brunswick, NJ, USA; Department of Pharmacology, Rutgers the State University of New Jersey, New Brunswick, NJ, USA.

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http://dx.doi.org/10.1038/celldisc.2016.39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088412PMC
November 2016

Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia.

Cancer Discov 2016 10 17;6(10):1166-1181. Epub 2016 Aug 17.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Pediatric Oncology, Dana-Farber Cancer Institute, and Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-16-0237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584808PMC
October 2016

Cullin3-KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression.

Genes Dev 2016 Sep;30(17):1956-70

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers University, The State University of New Jersey, New Brunswick, New Jersey 08903, USA; Department of Pharmacology, Rutgers University, The State University of New Jersey, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1101/gad.283283.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066239PMC
September 2016

TRIM32 is a novel negative regulator of p53.

Mol Cell Oncol 2015 Apr-Jun;2(2):e970951. Epub 2014 Dec 1.

Department of Radiation Oncology; Rutgers Cancer Institute of New Jersey; Rutgers, State University of New Jersey ; New Brunswick, NJ USA.

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http://dx.doi.org/10.4161/23723548.2014.970951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904883PMC
June 2016

microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis.

Oncotarget 2016 Feb;7(8):8783-96

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, NJ 08903, USA.

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http://dx.doi.org/10.18632/oncotarget.7088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891004PMC
February 2016

Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis.

Elife 2016 Jan 11;5:e10727. Epub 2016 Jan 11.

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, United States.

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http://dx.doi.org/10.7554/eLife.10727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749555PMC
January 2016

RRAD inhibits the Warburg effect through negative regulation of the NF-κB signaling.

Oncotarget 2015 Jun;6(17):14982-92

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, NJ, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558130PMC
http://dx.doi.org/10.18632/oncotarget.3719DOI Listing
June 2015

Tumor suppressor p53 and its mutants in cancer metabolism.

Cancer Lett 2015 Jan 24;356(2 Pt A):197-203. Epub 2013 Dec 24.

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, NJ 08903, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2013.12.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069248PMC
January 2015

The regulation of the p53/MDM2 feedback loop by microRNAs.

RNA Dis 2015;2(1):e502

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, NJ 08903, USA.

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https://www.researchgate.net/profile/Juan_Liu62/publication/
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http://www.smartscitech.com/index.php/RD/article/view/502
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http://dx.doi.org/10.14800/rd.502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435570PMC
January 2015

Red yeast rice repairs kidney damage and reduces inflammatory transcription factors in rat models of hyperlipidemia.

Exp Ther Med 2014 Dec 21;8(6):1737-1744. Epub 2014 Oct 21.

Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China.

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http://dx.doi.org/10.3892/etm.2014.2035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217782PMC
December 2014

Ionizing radiation sensitizes breast cancer cells to Bcl-2 inhibitor, ABT-737, through regulating Mcl-1.

Radiat Res 2014 Dec;182(6):618-25

a  Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.

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http://dx.doi.org/10.1667/RR13856.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523983PMC
December 2014

MicroRNA-339-5p inhibits colorectal tumorigenesis through regulation of the MDM2/p53 signaling.

Oncotarget 2014 Oct;5(19):9106-17

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, NJ, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253422PMC
http://dx.doi.org/10.18632/oncotarget.2379DOI Listing
October 2014

LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers.

Nat Commun 2014 Oct 17;5:5218. Epub 2014 Oct 17.

Rutgers Cancer Institute of New Jersey, Rutgers, the State University of New Jersey, New Brunswick, New Jersey 08903, USA.

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http://dx.doi.org/10.1038/ncomms6218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203416PMC
October 2014

Tumour-associated mutant p53 drives the Warburg effect.

Nat Commun 2013 ;4:2935

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers State University of New Jersey, New Brunswick, New Jersey 08902, USA.

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http://dx.doi.org/10.1038/ncomms3935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969270PMC
July 2014

Spliced MDM2 isoforms promote mutant p53 accumulation and gain-of-function in tumorigenesis.

Nat Commun 2013 ;4:2996

Department of Pediatrics, Rutgers Cancer Institute of New Jersey, Rutgers State University of New Jersey, New Brunswick, NJ 08903, USA.

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http://dx.doi.org/10.1038/ncomms3996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960723PMC
July 2014

Whole exome sequencing identifies a novel EMD mutation in a Chinese family with dilated cardiomyopathy.

BMC Med Genet 2014 Jul 5;15:77. Epub 2014 Jul 5.

State Key Lab of Medical Genetics, Central South University, 410008 Changsha, Hunan province, China.

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http://dx.doi.org/10.1186/1471-2350-15-77DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105140PMC
July 2014

Tumor suppressor p53 negatively regulates glycolysis stimulated by hypoxia through its target RRAD.

Oncotarget 2014 Jul;5(14):5535-46

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, USA.

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http://www.oncotarget.com/fulltext/2137
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170611PMC
http://dx.doi.org/10.18632/oncotarget.2137DOI Listing
July 2014

Tumor suppressor p53 and its gain-of-function mutants in cancer.

Acta Biochim Biophys Sin (Shanghai) 2014 Mar 29;46(3):170-9. Epub 2013 Dec 29.

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, NJ 08903, USA.

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https://academic.oup.com/abbs/article-lookup/doi/10.1093/abb
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http://dx.doi.org/10.1093/abbs/gmt144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932832PMC
March 2014

LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway.

Oncotarget 2014 Feb;5(3):788-801

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers State University of New Jersey, New Brunswick, NJ, USA.

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http://www.oncotarget.com/fulltext/1772
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996668PMC
http://dx.doi.org/10.18632/oncotarget.1772DOI Listing
February 2014

The regulation of cellular metabolism by tumor suppressor p53.

Cell Biosci 2013 Feb 6;3(1). Epub 2013 Feb 6.

The Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, 195 Little Albany Street, New Brunswick, NJ, 08903, USA.

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http://dx.doi.org/10.1186/2045-3701-3-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573943PMC
February 2013

PTEN, energy metabolism and tumor suppression.

Acta Biochim Biophys Sin (Shanghai) 2012 Aug 1;44(8):629-31. Epub 2012 Jul 1.

Department of Radiation Oncology, The Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08903, USA.

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http://dx.doi.org/10.1093/abbs/gms048DOI Listing
August 2012

Chronic restraint stress attenuates p53 function and promotes tumorigenesis.

Proc Natl Acad Sci U S A 2012 May 16;109(18):7013-8. Epub 2012 Apr 16.

Department of Radiation Oncology and Department of Pediatrics, Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08903, USA.

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http://dx.doi.org/10.1073/pnas.1203930109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345015PMC
May 2012

The Regulation of Multiple p53 Stress Responses is Mediated through MDM2.

Genes Cancer 2012 Mar;3(3-4):199-208

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ, USA.

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http://dx.doi.org/10.1177/1947601912454734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494373PMC
March 2012

TAp63γ enhances nucleotide excision repair through transcriptional regulation of DNA repair genes.

DNA Repair (Amst) 2012 Feb 6;11(2):167-76. Epub 2011 Nov 6.

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08903, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S156878641100311
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http://dx.doi.org/10.1016/j.dnarep.2011.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348579PMC
February 2012

Morphological and migratory alterations in retinal Müller cells during early stages of hypoxia and oxidative stress.

Neural Regen Res 2012 Jan;7(1):31-5

Department of Ophthalmology, Second Affiliated Hospital of Xi'an Jiaotong University Medical College, Xi'an 710004, Shaanxi Province, China.

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http://dx.doi.org/10.3969/j.issn.1673-5374.2012.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354112PMC
January 2012

Acrolein induced DNA damage, mutagenicity and effect on DNA repair.

Mol Nutr Food Res 2011 Sep 29;55(9):1291-300. Epub 2011 Jun 29.

Department of Environmental Medicine, New York University School of Medicine, Tuxedo Park, NY 10967, USA.

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http://dx.doi.org/10.1002/mnfr.201100148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606864PMC
September 2011

Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect.

Proc Natl Acad Sci U S A 2011 Sep 19;108(39):16259-64. Epub 2011 Sep 19.

Department of Radiation Oncology and Department of Pediatrics, Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08903, USA.

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http://dx.doi.org/10.1073/pnas.1113884108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182683PMC
September 2011

Regulation of female reproduction by p53 and its family members.

FASEB J 2011 Jul 14;25(7):2245-55. Epub 2011 Mar 14.

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey, USA.

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http://dx.doi.org/10.1096/fj.10-180166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114525PMC
July 2011

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.

Cancer Cell 2011 Jul;20(1):66-78

Division of Hematology/Oncology, Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ccr.2011.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329803PMC
July 2011

The Regulation of Aging and Longevity: A New and Complex Role of p53.

Genes Cancer 2011 Apr;2(4):443-52

Department of Radiation Oncology, The Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ, USA.

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http://dx.doi.org/10.1177/1947601911410223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135645PMC
April 2011

Tumor suppressor p53 meets microRNAs.

J Mol Cell Biol 2011 Feb;3(1):44-50

Department of Radiation Oncology, Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08903, USA.

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http://dx.doi.org/10.1093/jmcb/mjq040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030969PMC
February 2011

The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein.

Trends Cell Biol 2010 Jul;20(7):427-34

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08903, USA.

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http://dx.doi.org/10.1016/j.tcb.2010.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921989PMC
July 2010

Negative regulation of tumor suppressor p53 by microRNA miR-504.

Mol Cell 2010 Jun;38(5):689-99

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08903, USA.

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http://dx.doi.org/10.1016/j.molcel.2010.05.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900922PMC
June 2010

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function.

Proc Natl Acad Sci U S A 2010 Apr 8;107(16):7455-60. Epub 2010 Apr 8.

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08903, USA.

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http://dx.doi.org/10.1073/pnas.1001006107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867677PMC
April 2010

p53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment.

Authors:
Zhaohui Feng

Cold Spring Harb Perspect Biol 2010 Feb;2(2):a001057

Department of Radiation Oncology, Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey 08903, USA.

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http://dx.doi.org/10.1101/cshperspect.a001057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828273PMC
February 2010

[Development and application of lens parameters calculating software based on B ultrasound images].

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2010 Feb;27(1):174-7

Department of Ophthalmology, The 2nd Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710004, China.

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February 2010

The regulation of human reproduction by p53 and its pathway.

Cell Cycle 2009 Nov;8(22):3621-2

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http://dx.doi.org/10.4161/cc.8.22.9938DOI Listing
November 2009

Transformation from committed progenitor to leukemia stem cells.

Ann N Y Acad Sci 2009 Sep;1176:144-9

Division of Hematology/Oncology, Children's Hospital, Department of Pediatric Oncology, Dana Farber Cancer Institute, and Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://doi.wiley.com/10.1111/j.1749-6632.2009.04966.x
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http://dx.doi.org/10.1111/j.1749-6632.2009.04966.xDOI Listing
September 2009

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans.

Proc Natl Acad Sci U S A 2009 Jun 22;106(24):9761-6. Epub 2009 May 22.

Center for Reproductive Medicine and Infertility, Weill Cornell Medical College, New York, NY 10021, USA.

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http://dx.doi.org/10.1073/pnas.0904280106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700980PMC
June 2009

Gene expression profiling of leukemia stem cells.

Methods Mol Biol 2009 ;538:231-46

Department of Pediatric Oncology, Division of Hematology/Oncology, Children's Hospital, Dana Farber Cancer Insitute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/978-1-59745-418-6_11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339407PMC
May 2009

The tumor suppressor p53: cancer and aging.

Cell Cycle 2008 Apr 23;7(7):842-7. Epub 2008 Jan 23.

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey, USA.

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http://www.tandfonline.com/doi/abs/10.4161/cc.7.7.5657
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http://dx.doi.org/10.4161/cc.7.7.5657DOI Listing
April 2008

p53: a new player in reproduction.

Cell Cycle 2008 Apr 23;7(7):848-52. Epub 2008 Jan 23.

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey, USA.

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http://dx.doi.org/10.4161/cc.7.7.5658DOI Listing
April 2008

Reconstructing signal transduction pathways: challenges and opportunities.

Ann N Y Acad Sci 2007 Dec 12;1115:32-50. Epub 2007 Oct 12.

School of Natural Sciences, Institute for Advanced Study, Einstein Drive, Princeton, NJ 08540-0631, USA.

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http://dx.doi.org/10.1196/annals.1407.018DOI Listing
December 2007

p53 regulates maternal reproduction through LIF.

Nature 2007 Nov;450(7170):721-4

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey 08903, USA.

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http://dx.doi.org/10.1038/nature05993DOI Listing
November 2007

Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations.

Proc Natl Acad Sci U S A 2007 Oct 5;104(42):16633-8. Epub 2007 Oct 5.

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08903, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0708043104
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http://dx.doi.org/10.1073/pnas.0708043104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034252PMC
October 2007

A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells.

Cancer Res 2007 Mar;67(6):2757-65

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-2656DOI Listing
March 2007

Malondialdehyde, a major endogenous lipid peroxidation product, sensitizes human cells to UV- and BPDE-induced killing and mutagenesis through inhibition of nucleotide excision repair.

Mutat Res 2006 Oct 26;601(1-2):125-36. Epub 2006 Jul 26.

Department of Environmental Medicine, New York University School of Medicine, Tuxedo, NY 10987, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002751070600196
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http://dx.doi.org/10.1016/j.mrfmmm.2006.06.003DOI Listing
October 2006

Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair.

Proc Natl Acad Sci U S A 2006 Oct 9;103(42):15404-9. Epub 2006 Oct 9.

Department of Environmental Medicine, Pathology, and Medicine, New York University School of Medicine, Tuxedo, NY 10987, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0607031103
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http://dx.doi.org/10.1073/pnas.0607031103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592536PMC
October 2006

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

Nature 2006 Aug 16;442(7104):818-22. Epub 2006 Jul 16.

Division of Hematology/Oncology, Children's Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature04980DOI Listing
August 2006

Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways.

Genes Dev 2006 Feb;20(3):267-75

The Institute for Advanced Study, Princeton, New Jersey 08540, USA.

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http://dx.doi.org/10.1101/gad.1363206DOI Listing
February 2006

The coordinate regulation of the p53 and mTOR pathways in cells.

Proc Natl Acad Sci U S A 2005 Jun 31;102(23):8204-9. Epub 2005 May 31.

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA.

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http://dx.doi.org/10.1073/pnas.0502857102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142118PMC
June 2005

Chromium(VI) enhances (+/-)-anti-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene-induced cytotoxicity and mutagenicity in mammalian cells through its inhibitory effect on nucleotide excision repair.

Biochemistry 2004 Nov;43(44):14282-9

Department of Environmental Medicine, Pathology, and Medicine, New York University School of Medicine, Tuxedo, New York 10987, USA.

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http://dx.doi.org/10.1021/bi048560oDOI Listing
November 2004

Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response.

Mol Cell Biol 2004 Oct;24(20):9207-20

Department of Molecular Genetics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

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http://dx.doi.org/10.1128/MCB.24.20.9207-9220.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC517881PMC
October 2004

Differential effects of polycyclic aromatic hydrocarbons on transactivation of AP-1 and NF-kappaB in mouse epidermal cl41 cells.

Mol Carcinog 2004 Jun;40(2):104-15

Nelson Institute of Environmental Medicine, New York University School of Medicine, Tuxedo, New York, USA.

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http://dx.doi.org/10.1002/mc.20020DOI Listing
June 2004

Trans-4-hydroxy-2-nonenal inhibits nucleotide excision repair in human cells: a possible mechanism for lipid peroxidation-induced carcinogenesis.

Proc Natl Acad Sci U S A 2004 Jun;101(23):8598-602

Department of Environmental Medicine, New York University School of Medicine, Tuxedo, NY 10987, USA.

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http://dx.doi.org/10.1073/pnas.0402794101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC423240PMC
June 2004

Nickel (II) enhances benzo[a]pyrene diol epoxide-induced mutagenesis through inhibition of nucleotide excision repair in human cells: a possible mechanism for nickel (II)-induced carcinogenesis.

Carcinogenesis 2004 Mar 6;25(3):455-62. Epub 2003 Nov 6.

Department of Environmental Medicine, New York University School of Medicine, Tuxedo, NY 10987, USA.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgh012DOI Listing
March 2004

Effects of genomic context and chromatin structure on transcription-coupled and global genomic repair in mammalian cells.

Nucleic Acids Res 2003 Oct;31(20):5897-906

Department of Environmental Medicine, New York University School of Medicine, Tuxedo, NY 10987, USA and. Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC219485PMC
http://dx.doi.org/10.1093/nar/gkg808DOI Listing
October 2003

Preferential carcinogen-DNA adduct formation at codons 12 and 14 in the human K-ras gene and their possible mechanisms.

Biochemistry 2003 Aug;42(33):10012-23

Department of Environmental Medicine, New York University School of Medicine, Tuxedo, New York 10987, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi034631s
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August 2003

Mutational spectrum and genotoxicity of the major lipid peroxidation product, trans-4-hydroxy-2-nonenal, induced DNA adducts in nucleotide excision repair-proficient and -deficient human cells.

Biochemistry 2003 Jul;42(25):7848-54

Department of Environmental Medicine, New York University School of Medicine, Tuxedo, New York 10987, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi034431g
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July 2003

Gene expression of primary human bronchial epithelial cells in response to coal dusts with different prevalence of coal workers' pneumoconiosis.

J Toxicol Environ Health A 2003 Jul;66(13):1249-65

Department of Environmental Medicine, New York University School of Medicine, New York 10016, USA.

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http://dx.doi.org/10.1080/15287390306411DOI Listing
July 2003

Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production.

Nat Med 2003 Jun 18;9(6):756-61. Epub 2003 May 18.

Department of Medicine, Diabetes Research and Training Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1038/nm873DOI Listing
June 2003

Chromium(VI) exposure enhances polycyclic aromatic hydrocarbon-DNA binding at the p53 gene in human lung cells.

Carcinogenesis 2003 Apr;24(4):771-8

Department of Environmental Medicine, New York University School of Medicine, Tuxedo 10987, USA.

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http://dx.doi.org/10.1093/carcin/bgg012DOI Listing
April 2003

The major lipid peroxidation product, trans-4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma.

Carcinogenesis 2002 Nov;23(11):1781-9

Department of Environmental Medicine, Pathology and Medicine, New York University School of Medicine, Tuxedo, NY 10987, USA.

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http://dx.doi.org/10.1093/carcin/23.11.1781DOI Listing
November 2002

Transcription-coupled and transcription-independent repair of cyclobutane pyrimidine dimers in the dihydrofolate reductase gene.

J Biol Chem 2002 Oct 6;277(41):38305-10. Epub 2002 Aug 6.

Department of Environmental Medicine, Pathology, and Medicine, New York University School of Medicine, Tuxedo, New York 10987, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M206375200
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October 2002

4-aminobiphenyl is a major etiological agent of human bladder cancer: evidence from its DNA binding spectrum in human p53 gene.

Carcinogenesis 2002 Oct;23(10):1721-7

Department of Environmental Medicine, New York University School of Medicine, Tuxedo, NY 10987, USA.

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http://dx.doi.org/10.1093/carcin/23.10.1721DOI Listing
October 2002

Preferential DNA damage and poor repair determine ras gene mutational hotspot in human cancer.

J Natl Cancer Inst 2002 Oct;94(20):1527-36

Department of Environmental Medicine, New York University School of Medicine, Tuxedo 10987, USA.

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http://dx.doi.org/10.1093/jnci/94.20.1527DOI Listing
October 2002

Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats.

Nat Neurosci 2002 Jun;5(6):566-72

Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1038/nn0602-861DOI Listing
June 2002

Identification of a biochemical link between energy intake and energy expenditure.

J Clin Invest 2002 Jun;109(12):1599-605

Diabetes Research and Training Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1172/JCI15258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151013PMC
June 2002

N-hydroxy-4-aminobiphenyl-DNA binding in human p53 gene: sequence preference and the effect of C5 cytosine methylation.

Biochemistry 2002 May;41(20):6414-21

Department of Environmental Medicine, New York University Medical Center, Tuxedo, New York 10987, USA.

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http://dx.doi.org/10.1021/bi020093sDOI Listing
May 2002

Transcription-coupled DNA repair is genomic context-dependent.

J Biol Chem 2002 Apr 30;277(15):12777-83. Epub 2002 Jan 30.

Department of Environmental Medicine, Pathology and Medicine, New York University School of Medicine, Tuxedo, NY 10987, USA.

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http://dx.doi.org/10.1074/jbc.M112297200DOI Listing
April 2002

Mapping polycyclic aromatic hydrocarbon and aromatic amine-induced DNA damage in cancer-related genes at the sequence level.

Int J Hyg Environ Health 2002 Mar;205(1-2):103-13

Department of Environmental Medicine, New York University School of Medicine, 57 Old Forge Road, Tuxedo, NY 10987, USA.

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http://dx.doi.org/10.1078/1438-4639-00135DOI Listing
March 2002

Central administration of oleic acid inhibits glucose production and food intake.

Diabetes 2002 Feb;51(2):271-5

Departments of Medicine and Molecular Pharmacology, Diabetes Research and Training Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.2337/diabetes.51.2.271DOI Listing
February 2002