Zengqiang Yuan

Zengqiang Yuan

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Zengqiang Yuan

Publications by authors named "Zengqiang Yuan"

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High-dose Propofol Anesthesia Reduces the Occurrence of Postoperative Cognitive Dysfunction via Maintaining Cytoskeleton.

Neuroscience 2019 Nov 1;421:136-143. Epub 2019 Nov 1.

Department of Anesthesiology, Pain Medicine & CCM, Aviation General Hospital of China Medical University & Beijing Institute of Translational Medicine, Chinese Academy of Sciences, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2019.09.024DOI Listing
November 2019

Cyclin-Dependent Kinase 5-Dependent BAG3 Degradation Modulates Synaptic Protein Turnover.

Biol Psychiatry 2019 Nov 21. Epub 2019 Nov 21.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2019.11.013DOI Listing
November 2019

Hippo kinases regulate cell junctions to inhibit tumor metastasis in response to oxidative stress.

Redox Biol 2019 09 4;26:101233. Epub 2019 Jun 4.

Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064, China; Department of Biochemistry, Boston University School of Medicine, Boston, MA, 02118, USA. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582208PMC
September 2019

Deficiency of Yes-Associated Protein Induces Cataract in Mice.

Aging Dis 2019 Apr 1;10(2):293-306. Epub 2019 Apr 1.

2The Brain Science Center, Beijing Institute of Basic Medical Sciences, Beijing 100850, China.

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http://www.aginganddisease.org/EN/10.14336/AD.2018.0910
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http://dx.doi.org/10.14336/AD.2018.0910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457047PMC
April 2019

Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis.

Nat Commun 2019 02 14;10(1):755. Epub 2019 Feb 14.

State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian, 361102, China.

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http://dx.doi.org/10.1038/s41467-019-08680-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376064PMC
February 2019

Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation.

Neuron 2018 11 13;100(3):551-563.e7. Epub 2018 Sep 13.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.08.031DOI Listing
November 2018

Central role of autophagic UVRAG in melanogenesis and the suntan response.

Proc Natl Acad Sci U S A 2018 08 30;115(33):E7728-E7737. Epub 2018 Jul 30.

Department of Molecular Microbiology and Immunology, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033;

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http://dx.doi.org/10.1073/pnas.1803303115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099899PMC
August 2018

YAP promotes breast cancer metastasis by repressing growth differentiation factor-15.

Biochim Biophys Acta Mol Basis Dis 2018 May 28;1864(5 Pt A):1744-1753. Epub 2018 Feb 28.

College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2018.02.020DOI Listing
May 2018

A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ Size.

Dev Cell 2017 12;43(5):603-617.e5

The Brain Science Center, Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China; Center of Alzheimer's Disease, Beijing Institute for Brain Disorders, Beijing 100069, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15345807173090
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http://dx.doi.org/10.1016/j.devcel.2017.10.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722641PMC
December 2017

Mst-1 deficiency promotes post-traumatic spinal motor neuron survival via enhancement of autophagy flux.

J Neurochem 2017 10 19;143(2):244-256. Epub 2017 Sep 19.

Institute of Neuroscience, Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases, Soochow University, Suzhou, China.

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http://dx.doi.org/10.1111/jnc.14154DOI Listing
October 2017

Increased GSNOR Expression during Aging Impairs Cognitive Function and Decreases S-Nitrosation of CaMKIIα.

J Neurosci 2017 10 7;37(40):9741-9758. Epub 2017 Sep 7.

National Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Beijing 100101, China,

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http://dx.doi.org/10.1523/JNEUROSCI.0681-17.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596611PMC
October 2017

c-Abl-mediated Drp1 phosphorylation promotes oxidative stress-induced mitochondrial fragmentation and neuronal cell death.

Cell Death Dis 2017 10 12;8(10):e3117. Epub 2017 Oct 12.

The Brain Science Center, Beijing Institute of Basic Medical Sciences, Beijing 100850, China.

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http://dx.doi.org/10.1038/cddis.2017.524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682686PMC
October 2017

The function of NOD-like receptors in central nervous system diseases.

J Neurosci Res 2017 08 28;95(8):1565-1573. Epub 2016 Dec 28.

The State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.

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http://dx.doi.org/10.1002/jnr.24004DOI Listing
August 2017

Proteomic Analysis of HDAC3 Selective Inhibitor in the Regulation of Inflammatory Response of Primary Microglia.

Neural Plast 2017 15;2017:6237351. Epub 2017 Feb 15.

Department of Neurology, Affiliated Drum Tower Hospital, Nanjing University Medical school, Nanjing, Jiangsu 210008, China.

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http://dx.doi.org/10.1155/2017/6237351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331322PMC
August 2017

c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice.

Diabetologia 2017 05 10;60(5):900-910. Epub 2017 Jan 10.

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing, 100101, China.

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http://dx.doi.org/10.1007/s00125-016-4202-2DOI Listing
May 2017

Yki/Mask double-negative feedback loop mediates blood-brain barrier integrity in .

Proc Natl Acad Sci U S A 2017 03 6;114(12):E2365-E2374. Epub 2017 Mar 6.

Department of Biological Sciences, College of Basic Medical Sciences, Dalian Medical University, Dalian 116044, China;

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http://dx.doi.org/10.1073/pnas.1613233114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373330PMC
March 2017

Autophagy regulates MAVS signaling activation in a phosphorylation-dependent manner in microglia.

Cell Death Differ 2017 02 4;24(2):276-287. Epub 2016 Nov 4.

The State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

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http://dx.doi.org/10.1038/cdd.2016.121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299710PMC
February 2017

DJ-1 maintains energy and glucose homeostasis by regulating the function of brown adipose tissue.

Cell Discov 2017 14;3:16054. Epub 2017 Feb 14.

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences , Beijing, China.

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http://dx.doi.org/10.1038/celldisc.2016.54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309696PMC
February 2017

Rutin ameliorates obesity through brown fat activation.

FASEB J 2017 01 20;31(1):333-345. Epub 2016 Oct 20.

Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China;

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http://dx.doi.org/10.1096/fj.201600459RRDOI Listing
January 2017

Vps35-dependent recycling of Trem2 regulates microglial function.

Traffic 2016 12 1;17(12):1286-1296. Epub 2016 Nov 1.

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.

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http://dx.doi.org/10.1111/tra.12451DOI Listing
December 2016

Hippo/MST1 signaling mediates microglial activation following acute cerebral ischemia-reperfusion injury.

Brain Behav Immun 2016 07 22;55:236-248. Epub 2015 Dec 22.

Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2015.12.016DOI Listing
July 2016

SLC35D3 increases autophagic activity in midbrain dopaminergic neurons by enhancing BECN1-ATG14-PIK3C3 complex formation.

Autophagy 2016 07 12;12(7):1168-79. Epub 2016 May 12.

a State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences , Beijing , China.

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http://dx.doi.org/10.1080/15548627.2016.1179402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990987PMC
July 2016

NF-κB Upregulates Type 5 Phosphodiesterase in N9 Microglial Cells: Inhibition by Sildenafil and Yonkenafil.

Mol Neurobiol 2016 May 25;53(4):2647-58. Epub 2015 Jun 25.

Department of Pharmacology, Shenyang Pharmaceutical University, Box 31, 103 Wenhua Road, Shenyang, 110016, China.

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http://dx.doi.org/10.1007/s12035-015-9293-0DOI Listing
May 2016

IER5 promotes irradiation- and cisplatin-induced apoptosis in human hepatocellular carcinoma cells.

Am J Transl Res 2016 15;8(4):1789-98. Epub 2016 Apr 15.

National Institute for Radiological Protection, Chinese Center for Disease Control and PreventionBeijing 100088, China; Key Laboratory of Radiological Protection and Nuclear Emergency, Chinese Center for Disease Control and PreventionBeijing 100088, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859908PMC
May 2016

Malibatol A enhances alternative activation of microglia by inhibiting phosphorylation of Mammalian Ste20-like kinase1 in OGD-BV-2 cells.

Neurol Res 2016 Apr 21;38(4):342-8. Epub 2016 Apr 21.

a Department of Neurology , Drum Tower Hospital, Medical School of Nanjing University , Nanjing , PR China.

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http://dx.doi.org/10.1080/01616412.2016.1174423DOI Listing
April 2016

YAP enhances autophagic flux to promote breast cancer cell survival in response to nutrient deprivation.

PLoS One 2015 26;10(3):e0120790. Epub 2015 Mar 26.

Institute of Cancer Stem Cell, Dalian Medical University Cancer Center, Dalian, Liaoning, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120790PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374846PMC
March 2016

One-step generation of triple gene-targeted pigs using CRISPR/Cas9 system.

Sci Rep 2016 Feb 9;6:20620. Epub 2016 Feb 9.

State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.

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http://dx.doi.org/10.1038/srep20620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746670PMC
February 2016

Dysfunction of Wntless triggers the retrograde Golgi-to-ER transport of Wingless and induces ER stress.

Sci Rep 2016 Feb 18;6:19418. Epub 2016 Feb 18.

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

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http://dx.doi.org/10.1038/srep19418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757895PMC
February 2016

Amplified RLR signaling activation through an interferon-stimulated gene-endoplasmic reticulum stress-mitochondrial calcium uniporter protein loop.

Sci Rep 2016 Feb 19;6:20158. Epub 2016 Feb 19.

The State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

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http://dx.doi.org/10.1038/srep20158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759556PMC
February 2016

Mitochondrial calcium uniporter protein MCU is involved in oxidative stress-induced cell death.

Protein Cell 2015 Jun 11;6(6):434-42. Epub 2015 Mar 11.

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.

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http://dx.doi.org/10.1007/s13238-015-0144-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444813PMC
June 2015

CHD2 is Required for Embryonic Neurogenesis in the Developing Cerebral Cortex.

Stem Cells 2015 Jun;33(6):1794-806

State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, People's Republic of China.

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http://dx.doi.org/10.1002/stem.2001DOI Listing
June 2015

Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule.

Biochem J 2015 May;468(1):133-44

*National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China.

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http://dx.doi.org/10.1042/BJ20141473DOI Listing
May 2015

Brahma regulates the Hippo pathway activity through forming complex with Yki-Sd and regulating the transcription of Crumbs.

Cell Signal 2015 Mar 8;27(3):606-13. Epub 2014 Dec 8.

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2014.12.002DOI Listing
March 2015

The alteration of Hippo/YAP signaling in the development of hypertrophic cardiomyopathy.

Basic Res Cardiol 2014 29;109(5):435. Epub 2014 Aug 29.

Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, 36 Wuluju, Chaoyang District, Beijing, 100029, China.

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http://dx.doi.org/10.1007/s00395-014-0435-8DOI Listing
February 2015

The roles of Cdk5-mediated subcellular localization of FOXO1 in neuronal death.

J Neurosci 2015 Feb;35(6):2624-35

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Medical College, Xiamen University, Xiamen, 361005, Fujian Province, China,

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http://dx.doi.org/10.1523/JNEUROSCI.3051-14.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582140PMC
February 2015

Hippo signaling in stress response and homeostasis maintenance.

Acta Biochim Biophys Sin (Shanghai) 2015 Jan 4;47(1):2-9. Epub 2014 Dec 4.

State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China

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http://dx.doi.org/10.1093/abbs/gmu109DOI Listing
January 2015

Dynamic phosphorylation of CENP-A at Ser68 orchestrates its cell-cycle-dependent deposition at centromeres.

Dev Cell 2015 Jan 31;32(1):68-81. Epub 2014 Dec 31.

National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2014.11.030DOI Listing
January 2015

HDAC2 selectively regulates FOXO3a-mediated gene transcription during oxidative stress-induced neuronal cell death.

J Neurosci 2015 Jan;35(3):1250-9

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China, Center of Alzheimer's Disease, Beijing Institute for Brain Disorders, Beijing, 100069, China, and

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http://dx.doi.org/10.1523/JNEUROSCI.2444-14.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605534PMC
January 2015

E2F transcription factor 1 regulates cellular and organismal senescence by inhibiting Forkhead box O transcription factors.

J Biol Chem 2014 Dec 24;289(49):34205-13. Epub 2014 Oct 24.

From the State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China,

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http://dx.doi.org/10.1074/jbc.M114.587170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256352PMC
December 2014

Efficient bi-allelic gene knockout and site-specific knock-in mediated by TALENs in pigs.

Sci Rep 2014 Nov 5;4:6926. Epub 2014 Nov 5.

1] State Key laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, P. R. China, 100101 [2] Beijing Farm Animal Research Center, Institute of Zoology, Chinese Academy of Sciences, P. R. China, 100101.

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http://dx.doi.org/10.1038/srep06926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220281PMC
November 2014

DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosis.

Biochem J 2014 Sep;462(3):489-97

*State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

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http://www.biochemj.org/content/ppbiochemj/462/3/489.full.pd
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http://biochemj.org/lookup/doi/10.1042/BJ20140235
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http://dx.doi.org/10.1042/BJ20140235DOI Listing
September 2014

BMP2-SMAD signaling represses the proliferation of embryonic neural stem cells through YAP.

J Neurosci 2014 Sep;34(36):12039-48

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics,

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http://dx.doi.org/10.1523/JNEUROSCI.0486-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608470PMC
September 2014

Ezh2 regulates adult hippocampal neurogenesis and memory.

J Neurosci 2014 Apr;34(15):5184-99

State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China, University of Chinese Academy of Sciences, Beijing 100049, China, and Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

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http://dx.doi.org/10.1523/JNEUROSCI.4129-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609005PMC
April 2014

Endoplasmic reticulum stress activates telomerase.

Aging Cell 2014 Feb 22;13(1):197-200. Epub 2013 Oct 22.

Institute of Aging Research, Hangzhou Normal University School of Medicine, Hangzhou, 310036, China; Key Laboratory for Cell Proliferation and Regulation Biology of Ministry of Education, Beijing Normal University, Beijing, 100875, China.

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http://dx.doi.org/10.1111/acel.12161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326870PMC
February 2014

Mst1/Mst2 regulate development and function of regulatory T cells through modulation of Foxo1/Foxo3 stability in autoimmune disease.

J Immunol 2014 Feb 22;192(4):1525-35. Epub 2014 Jan 22.

State Key Laboratory of Genetic Engineering and Institute of Developmental Biology and Molecular Medicine, National Center for International Research of Development and Diseases, School of Life Sciences, Fudan University, Shanghai 200433, China;

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http://dx.doi.org/10.4049/jimmunol.1301060DOI Listing
February 2014

Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling.

Elife 2013 Oct 15;2:e00999. Epub 2013 Oct 15.

State Key Laboratory of Cell Biology , Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences , Shanghai , China.

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https://elifesciences.org/articles/00999
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http://dx.doi.org/10.7554/eLife.00999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796317PMC
October 2013

YAP/TEAD-mediated transcription controls cellular senescence.

Cancer Res 2013 Jun 10;73(12):3615-24. Epub 2013 Apr 10.

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-3793DOI Listing
June 2013

CAMKII and calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16.

Elife 2013 Jun 25;2:e00518. Epub 2013 Jun 25.

Graduate Program in Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China ; National Institute of Biological Sciences, Beijing , Beijing , China.

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http://dx.doi.org/10.7554/eLife.00518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691573PMC
June 2013

MST1, a key player, in enhancing fast skeletal muscle atrophy.

BMC Biol 2013 Feb 1;11:12. Epub 2013 Feb 1.

National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Datun Road 15, Beijing 100101, China.

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http://link.springer.com/content/pdf/10.1186%2F1741-7007-11-
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http://bmcbiol.biomedcentral.com/articles/10.1186/1741-7007-
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http://dx.doi.org/10.1186/1741-7007-11-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606410PMC
February 2013

Interleukin-22 protects rat PC12 pheochromocytoma cells from serum deprivation-induced cell death.

Mol Cell Biochem 2012 Dec 16;371(1-2):137-46. Epub 2012 Sep 16.

Northern Jiangsu People's Hospital, Nantong West Road No. 98, Yangzhou 225001, China.

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http://dx.doi.org/10.1007/s11010-012-1430-8DOI Listing
December 2012

Post-translational regulation of FOXO.

Acta Biochim Biophys Sin (Shanghai) 2012 Nov 30;44(11):897-901. Epub 2012 Aug 30.

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

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http://dx.doi.org/10.1093/abbs/gms067DOI Listing
November 2012

DJ-1 promotes the proteasomal degradation of Fis1: implications of DJ-1 in neuronal protection.

Biochem J 2012 Oct;447(2):261-9

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

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http://dx.doi.org/10.1042/BJ20120598DOI Listing
October 2012

Regulation of neuronal cell death by c-Abl-Hippo/MST2 signaling pathway.

PLoS One 2012 9;7(5):e36562. Epub 2012 May 9.

Institute of Cancer Stem Cell, Dalian Medical University Cancer Center, Liaoning, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036562PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348883PMC
September 2012

Generation of Calhm1 knockout mouse and characterization of calhm1 gene expression.

Protein Cell 2012 Jun 21;3(6):470-80. Epub 2012 Jun 21.

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.

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http://dx.doi.org/10.1007/s13238-012-2932-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875489PMC
June 2012

The tumor suppressor role of Src homology phosphotyrosine phosphatase 2 in hepatocellular carcinoma.

J Cancer Res Clin Oncol 2012 Apr 7;138(4):637-46. Epub 2012 Jan 7.

Pathology Department, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853, China.

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http://link.springer.com/10.1007/s00432-011-1143-5
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http://dx.doi.org/10.1007/s00432-011-1143-5DOI Listing
April 2012

Lysine methylation of FOXO3 regulates oxidative stress-induced neuronal cell death.

EMBO Rep 2012 Apr;13(4):371-7

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

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http://dx.doi.org/10.1038/embor.2012.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321157PMC
April 2012

PP1A-mediated dephosphorylation positively regulates YAP2 activity.

PLoS One 2011 1;6(9):e24288. Epub 2011 Sep 1.

State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024288PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164728PMC
January 2012

Methylation-mediated regulation of E2F1 in DNA damage-induced cell death.

J Recept Signal Transduct Res 2011 Apr 15;31(2):139-46. Epub 2011 Feb 15.

Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.

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http://dx.doi.org/10.3109/10799893.2011.552914DOI Listing
April 2011

MST1 promotes apoptosis through regulating Sirt1-dependent p53 deacetylation.

J Biol Chem 2011 Mar 6;286(9):6940-5. Epub 2011 Jan 6.

State Key Laboratory of Brain and Cognitive Sciences, Chinese Academy of Sciences, Beijing 100101, China.

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http://dx.doi.org/10.1074/jbc.M110.182543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044949PMC
March 2011

Redemystifying MST1/hippo signaling.

Protein Cell 2010 Aug;1(8):706-8

State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

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http://dx.doi.org/10.1007/s13238-010-0097-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875199PMC
August 2010

Ca(2+) release induced by cADP-ribose is mediated by FKBP12.6 proteins in mouse bladder smooth muscle.

Cell Calcium 2010 May 7;47(5):449-57. Epub 2010 May 7.

Urological Surgery Research Institute, Southwest Hospital, Third Military Medical University, Chongqing, China.

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http://dx.doi.org/10.1016/j.ceca.2010.03.006DOI Listing
May 2010

c-Jun N-terminal kinase enhances MST1-mediated pro-apoptotic signaling through phosphorylation at serine 82.

J Biol Chem 2010 Feb 22;285(9):6259-64. Epub 2009 Dec 22.

National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

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http://dx.doi.org/10.1074/jbc.M109.038570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825421PMC
February 2010

Regulation of neuronal cell death by MST1-FOXO1 signaling.

J Biol Chem 2009 Apr 16;284(17):11285-92. Epub 2009 Feb 16.

Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.M900461200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670133PMC
April 2009

Cell protective mechanism of valproic acid in lethal hemorrhagic shock.

Surgery 2008 Aug;144(2):217-24

Department of Surgery, Division of Trauma, Emergency Surgery and Surgical Critical Care, Massachusetts General Hospital/Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.surg.2008.03.037DOI Listing
August 2008

Prevention of hypoxia-induced neuronal apoptosis through histone deacetylase inhibition.

J Trauma 2008 Apr;64(4):863-70; discussion 870-1

Department of Surgery, Division of Trauma, Emergency Surgery and Surgical Critical Care, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA.

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April 2008

Advances of AKT pathway in human oncogenesis and as a target for anti-cancer drug discovery.

Curr Cancer Drug Targets 2008 Feb;8(1):2-6

Department of Microbiology, Mount Sinai School of Medicine, New York, NY 10029, USA.

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February 2008

Cell-intrinsic regulation of axonal morphogenesis by the Cdh1-APC target SnoN.

Neuron 2006 May;50(3):389-400

Department of Pathology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1016/j.neuron.2006.03.034DOI Listing
May 2006

A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiation.

Science 2006 Feb;311(5763):1012-7

Department of Pathology, Harvard Medical School, 77 Louis Pasteur Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/science.1122513DOI Listing
February 2006

Insulin-like growth factor 1 receptor enhances invasion and induces resistance to apoptosis of colon cancer cells through the Akt/Bcl-x(L) pathway.

Cancer Res 2003 Nov;63(22):7708-16

Department of Interdisciplinary Oncology, Moffitt Cancer Center and Research Institute, University of South Florida College of Medicine, 12902 Magnolia Drive, Tampa, FL 33612, USA.

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November 2003