Publications by authors named "Zemin Zhang"

100Publications

Landscape of transcript isoforms in single T cells infiltrating in non-small-cell lung cancer.

J Genet Genomics 2020 Jul 27. Epub 2020 Jul 27.

BIOPIC, Beijing Advanced Innovation Center for Genomics, School of Life Sciences, Peking University, Beijing, 100871, China. Electronic address:

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http://dx.doi.org/10.1016/j.jgg.2020.06.006DOI Listing
July 2020

Interfacial modification towards highly efficient and stable perovskite solar cells.

Nanoscale 2020 Sep 7;12(36):18563-18575. Epub 2020 Sep 7.

Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.

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http://dx.doi.org/10.1039/d0nr05136eDOI Listing
September 2020

The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications.

Cell Mol Immunol 2020 Aug 1;17(8):807-821. Epub 2020 Jul 1.

Beijing Advanced Innovation Center for Genomics, Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, 100871, Beijing, China.

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http://dx.doi.org/10.1038/s41423-020-0488-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395159PMC
August 2020

Dynamics of peripheral T cell clones during PD-1 blockade in non-small cell lung cancer.

Cancer Immunol Immunother 2020 Jun 26. Epub 2020 Jun 26.

Beijing Advanced Innovation Center for Genomics, School of Life Sciences, BIOPIC, Peking University, Beijing, 100871, China.

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http://dx.doi.org/10.1007/s00262-020-02642-4DOI Listing
June 2020

An entropy-based metric for assessing the purity of single cell populations.

Nat Commun 2020 06 22;11(1):3155. Epub 2020 Jun 22.

School of Life Sciences, BIOPIC and Beijing Advanced Innovation Centre for Genomics, Peking University, Beijing, China.

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http://dx.doi.org/10.1038/s41467-020-16904-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308400PMC
June 2020

Reconstruction of cell spatial organization from single-cell RNA sequencing data based on ligand-receptor mediated self-assembly.

Cell Res 2020 Sep 15;30(9):763-778. Epub 2020 Jun 15.

Beijing Advanced Innovation Centre for Genomics, Peking-Tsinghua Centre for Life Sciences, Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, 100871, Beijing, China.

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http://dx.doi.org/10.1038/s41422-020-0353-2DOI Listing
September 2020

Production Assessment and Genome Comparison Revealed High Yield Potential and Novel Specific Alleles Associated with Fertility and Yield in Neo-Tetraploid Rice.

Rice (N Y) 2020 Jun 3;13(1):32. Epub 2020 Jun 3.

State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, Guangzhou, 510642, China.

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http://dx.doi.org/10.1186/s12284-020-00387-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271338PMC
June 2020

SciBet as a portable and fast single cell type identifier.

Nat Commun 2020 04 14;11(1):1818. Epub 2020 Apr 14.

Peking-Tsinghua Center for Life Sciences, BIOPIC and School of Life Sciences, Peking University, Beijing, China.

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http://dx.doi.org/10.1038/s41467-020-15523-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156687PMC
April 2020

Plasma Membrane Ca Permeable Mechanosensitive Channel Is Involved in Regulation of Plant Architecture and Ion Homeostasis in Rice.

Int J Mol Sci 2020 Feb 7;21(3). Epub 2020 Feb 7.

State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China.

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http://dx.doi.org/10.3390/ijms21031097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037369PMC
February 2020

Systematic comparative analysis of single-nucleotide variant detection methods from single-cell RNA sequencing data.

Genome Biol 2019 11 19;20(1):242. Epub 2019 Nov 19.

School of Life Sciences and BIOPIC, Peking University, Beijing, China.

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http://dx.doi.org/10.1186/s13059-019-1863-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862814PMC
November 2019

Understanding tumor-infiltrating lymphocytes by single cell RNA sequencing.

Adv Immunol 2019 12;144:217-245. Epub 2019 Sep 12.

Beijing Advanced Innovation Centre for Genomics, Peking-Tsinghua Centre for Life Sciences, Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, Beijing, China.

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http://dx.doi.org/10.1016/bs.ai.2019.08.004DOI Listing
May 2020

Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma.

Cell 2019 Oct;179(4):829-845.e20

BIOPIC, Beijing Advanced Innovation Center for Genomics, School of Life Sciences, Peking University, Beijing 100871, China; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.10.003DOI Listing
October 2019

Identification of transcriptional isoforms associated with survival in cancer patient.

J Genet Genomics 2019 09 25;46(9):413-421. Epub 2019 Sep 25.

School of Life Sciences and BIOPIC, Peking University, Beijing, 100871, China; Beijing Advanced Innovation Centre for Genomics, Peking-Tsinghua Centre for Life Sciences, Peking University, Beijing, 100871, China. Electronic address:

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http://dx.doi.org/10.1016/j.jgg.2019.08.003DOI Listing
September 2019

hCINAP regulates the DNA-damage response and mediates the resistance of acute myelocytic leukemia cells to therapy.

Nat Commun 2019 08 23;10(1):3812. Epub 2019 Aug 23.

State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, 100871, China.

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http://www.nature.com/articles/s41467-019-11795-5
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http://dx.doi.org/10.1038/s41467-019-11795-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707248PMC
August 2019

Deep single-cell RNA sequencing data of individual T cells from treatment-naïve colorectal cancer patients.

Sci Data 2019 07 24;6(1):131. Epub 2019 Jul 24.

School of Life Sciences and BIOPIC, Peking University, Beijing, 100871, China.

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http://dx.doi.org/10.1038/s41597-019-0131-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656756PMC
July 2019

Recharacterizing Tumor-Infiltrating Lymphocytes by Single-Cell RNA Sequencing.

Cancer Immunol Res 2019 07;7(7):1040-1046

Beijing Advanced Innovation Center for Genomics, Peking-Tsinghua Center for Life Sciences, BIOPIC and School of Life Sciences, Peking University, Beijing, China.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0658DOI Listing
July 2019

LILRB1 Blockade Enhances Bispecific T Cell Engager Antibody-Induced Tumor Cell Killing by Effector CD8 T Cells.

J Immunol 2019 08 28;203(4):1076-1087. Epub 2019 Jun 28.

Department of Inflammation and Oncology, Amgen Research, Amgen Inc., South San Francisco, CA 94080;

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http://dx.doi.org/10.4049/jimmunol.1801472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680066PMC
August 2019

SSCC: A Novel Computational Framework for Rapid and Accurate Clustering Large-scale Single Cell RNA-seq Data.

Genomics Proteomics Bioinformatics 2019 04 13;17(2):201-210. Epub 2019 Jun 13.

BIOPIC, Beijing Advanced Innovation Center for Genomics, and School of Life Sciences, Peking University, Beijing 100871, China. Electronic address:

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http://dx.doi.org/10.1016/j.gpb.2018.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624216PMC
April 2019

Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes.

Cancer Cell 2019 06 23;35(6):932-947.e8. Epub 2019 May 23.

Biomedical Pioneering Innovation Center (BIOPIC) and Translational Cancer Research Center, School of Life Sciences, First Hospital, Peking University, Beijing 100871, China; Laboratory of Cancer Cell Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.04.007DOI Listing
June 2019

GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis.

Nucleic Acids Res 2019 07;47(W1):W556-W560

School of Life Sciences and BIOPIC, Peking University, Beijing 100871, China.

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https://academic.oup.com/nar/advance-article/doi/10.1093/nar
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http://dx.doi.org/10.1093/nar/gkz430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602440PMC
July 2019

Understanding tumor ecosystems by single-cell sequencing: promises and limitations.

Genome Biol 2018 12 3;19(1):211. Epub 2018 Dec 3.

Beijing Advanced Innovation Centre for Genomics, Peking-Tsinghua Centre for Life Sciences, Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, Beijing, 100871, China.

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http://dx.doi.org/10.1186/s13059-018-1593-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276232PMC
December 2018

Lineage tracking reveals dynamic relationships of T cells in colorectal cancer.

Nature 2018 12 29;564(7735):268-272. Epub 2018 Oct 29.

Beijing Advanced Innovation Centre for Genomics, Peking-Tsinghua Centre for Life Sciences, Peking University, Beijing, China.

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http://www.nature.com/articles/s41586-018-0694-x
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http://dx.doi.org/10.1038/s41586-018-0694-xDOI Listing
December 2018

Constitutive expression of REL1 confers the rice response to drought stress and abscisic acid.

Rice (N Y) 2018 Oct 25;11(1):59. Epub 2018 Oct 25.

State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, China.

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https://thericejournal.springeropen.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12284-018-0251-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202306PMC
October 2018

An automatic skill evaluation framework for robotic surgery training.

Int J Med Robot 2019 Feb 17;15(1):e1964. Epub 2018 Oct 17.

Key Lab for Mechanism Theory and Equipment Design of Ministry of Education, Tianjin University, Tianjin, China.

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http://doi.wiley.com/10.1002/rcs.1964
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http://dx.doi.org/10.1002/rcs.1964DOI Listing
February 2019

Comutations in DNA Damage Response Pathways Serve as Potential Biomarkers for Immune Checkpoint Blockade.

Cancer Res 2018 11 31;78(22):6486-6496. Epub 2018 Aug 31.

State Key Laboratory of Molecular Oncology, Department of Medical Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P.R. China.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-18-1814DOI Listing
November 2018

A20/TNFAIP3 Regulates the DNA Damage Response and Mediates Tumor Cell Resistance to DNA-Damaging Therapy.

Cancer Res 2018 02 12;78(4):1069-1082. Epub 2017 Dec 12.

State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-17-2143DOI Listing
February 2018

Significantly improved charge collection and interface injection in 3D BiVO based multilayered core-shell nanowire photocatalysts.

Nanoscale 2017 Sep;9(37):14015-14022

School of Physical Science and Technology, Lanzhou University, Lanzhou 730000, China.

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http://dx.doi.org/10.1039/c7nr05285eDOI Listing
September 2017

Influence of π-bridge conjugation on the electrochemical properties within hole transporting materials for perovskite solar cells.

Nanoscale 2017 Sep;9(35):12916-12924

Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.

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http://dx.doi.org/10.1039/c7nr04026aDOI Listing
September 2017

Theoretical insights into the effect of a conjugated core on the hole transport properties of hole-transporting materials for perovskite solar cells.

Phys Chem Chem Phys 2017 Sep;19(36):24574-24582

Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.

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http://dx.doi.org/10.1039/c7cp04754aDOI Listing
September 2017

Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing.

Cell 2017 Jun;169(7):1342-1356.e16

BIOPIC, Beijing Advanced Innovation Center for Genomics, and School of Life Sciences, Peking University, Beijing 100871, China; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674173059
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http://dx.doi.org/10.1016/j.cell.2017.05.035DOI Listing
June 2017

Sumoylation E3 Ligase SIZ1 Modulates Plant Immunity Partly through the Immune Receptor Gene SNC1 in Arabidopsis.

Mol Plant Microbe Interact 2017 04 14;30(4):334-342. Epub 2017 Apr 14.

1 Plant Biology Section, School of Integrated Plant Science, Cornell University, Ithaca, NY 14853, U.S.A.

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http://apsjournals.apsnet.org/doi/10.1094/MPMI-02-17-0041-R
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http://dx.doi.org/10.1094/MPMI-02-17-0041-RDOI Listing
April 2017

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses.

Nucleic Acids Res 2017 07;45(W1):W98-W102

BIOPIC, School of Life Sciences, Peking University, Beijing 100871, China.

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http://dx.doi.org/10.1093/nar/gkx247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570223PMC
July 2017

Development of a platform for breeding by design of CMS restorer lines based on an SSSL library in rice ( L.).

Breed Sci 2016 Dec 18;66(5):768-775. Epub 2016 Nov 18.

State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University , Guangzhou 510642 , China.

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https://www.jstage.jst.go.jp/article/jsbbs/66/5/66_16044/_ar
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http://dx.doi.org/10.1270/jsbbs.16044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282752PMC
December 2016

ER-localized adenine nucleotide transporter ER-ANT1: an integrator of energy and stress signaling in rice.

Plant Mol Biol 2016 Dec 10;92(6):701-715. Epub 2016 Sep 10.

The State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou, 510642, China.

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http://dx.doi.org/10.1007/s11103-016-0540-1DOI Listing
December 2016

Albino Leaf 2 is involved in the splicing of chloroplast group I and II introns in rice.

J Exp Bot 2016 10 19;67(18):5339-5347. Epub 2016 Aug 19.

State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, College of Agriculture, South China Agricultural University, Guangzhou 510642, China

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049385PMC
http://dx.doi.org/10.1093/jxb/erw296DOI Listing
October 2016

Nanostructured CuS networks composed of interconnected nanoparticles for asymmetric supercapacitors.

Phys Chem Chem Phys 2016 Sep 19;18(35):24471-6. Epub 2016 Aug 19.

School of Physical Science and Technology, Lanzhou University, Lanzhou 730000, China.

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http://dx.doi.org/10.1039/c6cp02228fDOI Listing
September 2016

Overcoming inter-subspecific hybrid sterility in rice by developing indica-compatible japonica lines.

Sci Rep 2016 06 1;6:26878. Epub 2016 Jun 1.

State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, Guangzhou 510642, China.

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http://dx.doi.org/10.1038/srep26878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887987PMC
June 2016

Albino Leaf1 That Encodes the Sole Octotricopeptide Repeat Protein Is Responsible for Chloroplast Development.

Plant Physiol 2016 06 22;171(2):1182-91. Epub 2016 Apr 22.

State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China (Z.Z., J.T., Q.X., Y.X., C.L., Q.C., H.Z., G.Z.); andShanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 20032, China (Z.S., J.W., J.Z.)

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http://dx.doi.org/10.1104/pp.16.00325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902615PMC
June 2016

Variable Intra-Tumor Genomic Heterogeneity of Multiple Lesions in Patients With Hepatocellular Carcinoma.

Gastroenterology 2016 Apr 2;150(4):998-1008. Epub 2016 Jan 2.

Laboratory of Cancer Cell Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China; Research Center of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.12.033DOI Listing
April 2016

Understanding the Genetic Mechanisms of Cancer Drug Resistance Using Genomic Approaches.

Trends Genet 2016 Feb 13;32(2):127-137. Epub 2015 Dec 13.

BIOPIC and College of Life Sciences, Peking University, Beijing, 100871, China; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, 100871, China. Electronic address:

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http://dx.doi.org/10.1016/j.tig.2015.11.003DOI Listing
February 2016

Opposing Effects on Two Phases of Defense Responses from Concerted Actions of HEAT SHOCK COGNATE70 and BONZAI1 in Arabidopsis.

Plant Physiol 2015 Nov 25;169(3):2304-23. Epub 2015 Sep 25.

Plant Biology Section, School of Integrated Plant Science, Cornell University, Ithaca, New York 14853 (M.G., Z.Z., N.Z., Q.H., H.Y., Z.S., J.H.);State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Agriculture, South China Agricultural University, Guangzhou 510642, China (Z.Z.);State Key Laboratory of Rice Biology, Institute of Nuclear Agricultural Sciences, Zhejiang University, Hangzhou 310029, China (N.Z.);Institute of Nuclear and Biological Technology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, China (Q.H.);The Sainsbury Laboratory, Norwich Research Park, Norwich NR4 7UH, United Kingdom (J.M., C.Z.); andShanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China (Z.S.)

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http://dx.doi.org/10.1104/pp.15.00970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634071PMC
November 2015

Activation of the BMP-BMPR pathway conferred resistance to EGFR-TKIs in lung squamous cell carcinoma patients with EGFR mutations.

Proc Natl Acad Sci U S A 2015 Aug 27;112(32):9990-5. Epub 2015 Jul 27.

Department of Thoracic Medical Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing Cancer Hospital & Beijing Institute for Cancer Research, Beijing 100142, China;

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http://dx.doi.org/10.1073/pnas.1510837112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538677PMC
August 2015

Characterization of Rolled and Erect Leaf 1 in regulating leave morphology in rice.

J Exp Bot 2015 Sep 2;66(19):6047-58. Epub 2015 Jul 2.

State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, China

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http://jxb.oxfordjournals.org/content/early/2015/07/01/jxb.e
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http://jxb.oxfordjournals.org/content/66/19/6047.full.pdf
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http://jxb.oxfordjournals.org/lookup/doi/10.1093/jxb/erv319
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http://dx.doi.org/10.1093/jxb/erv319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566990PMC
September 2015

Light illuminated α-Fe2O3/Pt nanoparticles as water activation agent for photoelectrochemical water splitting.

Sci Rep 2015 Mar 16;5:9130. Epub 2015 Mar 16.

School of Physical Science and Technology, Lanzhou University, Lanzhou 730000, Gansu, P.R. China.

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http://dx.doi.org/10.1038/srep09130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390902PMC
March 2015

Comparative oncogenomics identifies PSMB4 and SHMT2 as potential cancer driver genes.

Cancer Res 2014 Jun 22;74(11):3114-26. Epub 2014 Apr 22.

Authors' Affiliations: Departments of Discovery Oncology, Molecular Biology, Bioinformatics, Pathology, and Molecular Oncology, Genentech Inc., South San Francisco, California

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-2683DOI Listing
June 2014

Assessment of computational methods for predicting the effects of missense mutations in human cancers.

BMC Genomics 2013 28;14 Suppl 3:S7. Epub 2013 May 28.

Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1186/1471-2164-14-S3-S7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665581PMC
October 2013

Genomic landscape of liver cancer.

Authors:
Zemin Zhang

Nat Genet 2012 Oct;44(10):1075-7

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http://www.nature.com/articles/ng.2412
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http://dx.doi.org/10.1038/ng.2412DOI Listing
October 2012

Unconditional and conditional QTL mapping for the developmental behavior of tiller number in rice (Oryza sativa L.).

Genetica 2010 Aug 11;138(8):885-93. Epub 2010 Jul 11.

Guangdong Key Lab of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, People's Republic of China.

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http://dx.doi.org/10.1007/s10709-010-9471-yDOI Listing
August 2010

Inferring the functional effects of mutation through clusters of mutations in homologous proteins.

Hum Mutat 2010 Mar;31(3):264-71

Department of Bioinformatics, Genentech Inc, South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1002/humu.21194DOI Listing
March 2010

Bi-directional SIFT predicts a subset of activating mutations.

PLoS One 2009 Dec 14;4(12):e8311. Epub 2009 Dec 14.

Department of Bioinformatics, Genentech, Inc., South San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008311PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788704PMC
December 2009

Analytical methods for inferring functional effects of single base pair substitutions in human cancers.

Hum Genet 2009 Oct 12;126(4):481-98. Epub 2009 May 12.

Department of Bioinformatics, Genentech, Inc., 1 DNA Way, M.S. 93, South San Francisco, CA 94080, USA.

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http://link.springer.com/10.1007/s00439-009-0677-y
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http://dx.doi.org/10.1007/s00439-009-0677-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762536PMC
October 2009

Dynamic expression of nine QTLs for tiller number detected with single segment substitution lines in rice.

Theor Appl Genet 2009 Feb 24;118(3):443-53. Epub 2008 Oct 24.

Guangdong Key Lab of Plant Molecular Breeding, South China Agricultural University, 510642, Guangzhou, People's Republic of China.

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http://dx.doi.org/10.1007/s00122-008-0911-3DOI Listing
February 2009

Computational prediction of the functional effects of amino acid substitutions in signal peptides using a model-based approach.

Hum Mutat 2009 Jan;30(1):99-106

Department of Bioinformatics, Genentech, Inc., South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1002/humu.20798DOI Listing
January 2009

Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspective.

Genome Biol 2008 Apr 8;9(4):R69. Epub 2008 Apr 8.

Department of Bioinformatics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.

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http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
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http://dx.doi.org/10.1186/gb-2008-9-4-r69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643940PMC
April 2008

High-resolution genomic and expression analyses of copy number alterations in breast tumors.

Genes Chromosomes Cancer 2008 Jun;47(6):530-42

Department of Bioinformatics, Genentech, Inc., South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1002/gcc.20558DOI Listing
June 2008

Identification and fine mapping of S-d, a new locus conferring the partial pollen sterility of intersubspecific F1 hybrids in rice (Oryza sativa L.).

Theor Appl Genet 2008 May 15;116(7):915-22. Epub 2008 Feb 15.

Guangdong Provincial Key Lab of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China.

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http://dx.doi.org/10.1007/s00122-008-0723-5DOI Listing
May 2008

Detection of QTLs with additive effects and additive-by-environment interaction effects on panicle number in rice (Oryza sativa L.) with single-segment substitution lines.

Theor Appl Genet 2008 May 15;116(7):923-31. Epub 2008 Feb 15.

Guangdong Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, People's Republic of China.

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http://dx.doi.org/10.1007/s00122-008-0724-4DOI Listing
May 2008

DUBA: a deubiquitinase that regulates type I interferon production.

Science 2007 Dec 8;318(5856):1628-32. Epub 2007 Nov 8.

Department of Physiological Chemistry, Genentech, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1126/science.1145918DOI Listing
December 2007

The roles of binding site arrangement and combinatorial targeting in microRNA repression of gene expression.

Genome Biol 2007 ;8(8):R166

Department of Bioinformatics, Genentech Inc, 1 DNA Way, South San Francisco, CA 94080, USA.

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http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
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http://dx.doi.org/10.1186/gb-2007-8-8-r166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374997PMC
February 2008

GeneHub-GEPIS: digital expression profiling for normal and cancer tissues based on an integrated gene database.

Nucleic Acids Res 2007 Jul 1;35(Web Server issue):W152-8. Epub 2007 Jun 1.

Department of Bioinformatics, Genentech, Inc., South San Francisco, CA 94080, USA.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkm381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933245PMC
July 2007

CanPredict: a computational tool for predicting cancer-associated missense mutations.

Nucleic Acids Res 2007 Jul 30;35(Web Server issue):W595-8. Epub 2007 May 30.

Department of Bioinformatics, Genentech, Inc., South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1093/nar/gkm405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933186PMC
July 2007

Expression profiling of the mouse prostate after castration and hormone replacement: implication of H-cadherin in prostate tumorigenesis.

Differentiation 2007 Mar 11;75(3):219-34. Epub 2006 Dec 11.

Department of Molecular Biology, MS 72, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S030146810960117
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http://dx.doi.org/10.1111/j.1432-0436.2006.00135.xDOI Listing
March 2007

Bioinformatics and cancer target discovery.

Drug Discov Today 2004 Sep;9(18):795-802

Department of Bioinformatics, Genentech, 1 DNA Way, M.S. 93, South San Francisco, CA 94080, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S135964460403224
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http://dx.doi.org/10.1016/S1359-6446(04)03224-6DOI Listing
September 2004

Signal peptide prediction based on analysis of experimentally verified cleavage sites.

Protein Sci 2004 Oct 31;13(10):2819-24. Epub 2004 Aug 31.

Department of Bioinformatics, Genentech, Inc., South San Francisco, CA 94080, USA.

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https://pdfs.semanticscholar.org/4ba3/87f1751644bdee5d401c9e
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http://doi.wiley.com/10.1110/ps.04682504
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http://dx.doi.org/10.1110/ps.04682504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2286551PMC
October 2004

Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase.

Science 2004 Feb 22;303(5662):1371-4. Epub 2004 Jan 22.

Department of Molecular Oncology, Genentech, Inc., South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1126/science.1093549DOI Listing
February 2004

Genome-wide identification of chromosomal regions of increased tumor expression by transcriptome analysis.

Cancer Res 2003 Sep;63(18):5781-4

Department of Bioinformatics, Genentech, Inc., South San Francisco, California 94080, USA.

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September 2003