Dr. Zbigniew K Binienda, DVM, PhD - FDA/NCTR - Research Scientist

Dr. Zbigniew K Binienda

DVM, PhD

FDA/NCTR

Research Scientist

Little Rock, AR | United States

Main Specialties: Neurology

Additional Specialties: Neurophysiology; Neurotoxicology

Dr. Zbigniew K Binienda, DVM, PhD - FDA/NCTR - Research Scientist

Dr. Zbigniew K Binienda

DVM, PhD

Introduction

Primary Affiliation: FDA/NCTR - Little Rock, AR , United States

Specialties:

Additional Specialties:

Publications

16Publications

361Reads

-Profile Views

80PubMed Central Citations

The Carnitine Palmitoyl Transferase (CPT) System and Possible Relevance for Neuropsychiatric and Neurological Conditions.

Mol Neurobiol 2015 Oct 4;52(2):826-36. Epub 2015 Jun 4.

Research, Innovation and Development, Sigma-tau Health Science International BV, Utrecht, Netherlands,

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http://dx.doi.org/10.1007/s12035-015-9238-7DOI Listing
October 2015
47 Reads
4 Citations
5.140 Impact Factor

Neuroprotective efficacy of a new brain-penetrating C-Abl inhibitor in a murine Parkinson's disease model.

PLoS One 2013 31;8(5):e65129. Epub 2013 May 31.

Division of Neurotoxicology, US FDA/National Center for Toxicological Research, Jefferson, Arkansas, United States of America.

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http://www.biomedsearch.com/attachments/00/23/74/14/23741470
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http://dx.plos.org/10.1371/journal.pone.0065129
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0065129PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669292PMC
January 2014
151 Reads
20 Citations
3.234 Impact Factor

Chronic exposure to rotenone, a dopaminergic toxin, results in peripheral neuropathy associated with dopaminergic damage.

Neurosci Lett 2013 Apr 7;541:233-7. Epub 2013 Mar 7.

Division of Neurotoxicology, National Center for Toxicological Research/US FDA, Jefferson, AR 72079, United States.

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http://dx.doi.org/10.1016/j.neulet.2013.02.047DOI Listing
April 2013
7 Reads
3 Citations
2.060 Impact Factor

Molecular aspects of dopaminergic neurodegeneration: gene-environment interaction in parkin dysfunction.

Int J Environ Res Public Health 2011 12 16;8(12):4702-13. Epub 2011 Dec 16.

Neurochemistry Laboratory, Division of Neurotoxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72029, USA.

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http://dx.doi.org/10.3390/ijerph8124702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290988PMC
December 2011
59 Reads
8 Citations
2.063 Impact Factor

Buprenorphine modulates methamphetamine-induced dopamine dynamics in the rat caudate nucleus.

Neurotox Res 2011 Jan 22;19(1):94-101. Epub 2009 Dec 22.

Institute of Pharmacology and Therapeutics, Biomedical Institute for Research in Light and Image, Faculty of Medicine, University of Coimbra, Subunit 1-Polo 3, Azinhaga de Santa Comba, Celas, 3000-354 Coimbra, Portugal.

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http://dx.doi.org/10.1007/s12640-009-9143-9DOI Listing
January 2011
19 Reads
2 Citations
3.540 Impact Factor

Assessment of 3-nitropropionic acid-evoked peripheral neuropathy in rats: neuroprotective effects of acetyl-l-carnitine and resveratrol.

Neurosci Lett 2010 Aug 11;480(2):117-21. Epub 2010 Jun 11.

Division of Neurotoxicology, National Center for Toxicological Research/FDA, AR 72079, USA.

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http://dx.doi.org/10.1016/j.neulet.2010.06.020DOI Listing
August 2010
2 Reads
3 Citations
2.060 Impact Factor

Neuroprotective strategies in drug abuse-evoked encephalopathy.

Ann N Y Acad Sci 2010 Jun;1199:52-68

Scientific & Medical Affairs, Sigma tau, Pomezia 00040, Roma, Italy.

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http://dx.doi.org/10.1111/j.1749-6632.2009.05171.xDOI Listing
June 2010
20 Reads
3 Citations
4.313 Impact Factor

Metabolic syndrome in drug abuse.

Ann N Y Acad Sci 2007 Dec;1122:50-68

Research and Development, Sigma tau-HealthScience, Via Treviso 4, Pomezia 00040, Italy.

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http://dx.doi.org/10.1196/annals.1403.004DOI Listing
December 2007
8 Reads
9 Citations
4.313 Impact Factor

Co-regulation of dopamine D1 receptor and uncoupling protein-2 expression in 3-nitropropionic acid-induced neurotoxicity: neuroprotective role of L-carnitine.

Neurosci Lett 2006 Dec 18;410(1):62-5. Epub 2006 Oct 18.

Division of Neurotoxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1016/j.neulet.2006.09.070DOI Listing
December 2006
1 Read
3 Citations
2.060 Impact Factor

Effects of L-carnitine pretreatment in methamphetamine and 3-nitropropionic acid-induced neurotoxicity.

Ann N Y Acad Sci 2006 Aug;1074:74-83

Division of Neurotoxicology, HFT-132, FDA/NCTR, Jefferson, AR 72079-9502, USA.

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http://dx.doi.org/10.1196/annals.1369.006DOI Listing
August 2006
1 Read
1 Citation
4.313 Impact Factor

Identification of rat hippocampal mRNAs altered by the mitochondrial toxicant, 3-NPA.

Ann N Y Acad Sci 2005 Aug;1053:162-73

Division of Neurotoxicology, HFT-132, National Center for Toxicology Research, Food and Drug Administration, Jefferson, Arkansas 72079-9502, USA.

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http://dx.doi.org/10.1196/annals.1344.014DOI Listing
August 2005
3 Reads
5 Citations
4.313 Impact Factor

The differential JunB responses to inhibition of succinate dehydrogenase in rat hippocampus and liver.

Neurosci Lett 2005 Jun 28;381(3):354-7. Epub 2005 Mar 28.

Division of Neurotoxicology, FDA/National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079-9502, USA.

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http://dx.doi.org/10.1016/j.neulet.2005.02.049DOI Listing
June 2005
18 Reads
1 Citation
2.060 Impact Factor

Electroencephalographic, behavioral, and c-fos responses to acute domoic acid exposure.

Neurotoxicol Teratol 2004 Mar-Apr;26(2):331-42

Division of Neurotoxicology, National Center for Toxicological Research, USFDA, 3900 NCTR Drive, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1016/j.ntt.2003.10.004DOI Listing
May 2004
2 Reads
7 Citations
2.762 Impact Factor

Neuroprotective effects of L-carnitine in induced mitochondrial dysfunction.

Ann N Y Acad Sci 2003 May;993:289-95; discussion 345-9

Neurophysiology Laboratory, Division of Neurotoxicology, National Center for Toxicological Research/FDA, Jefferson, Arkansas 72079, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2003.tb07536.xDOI Listing
May 2003
1 Read
6 Citations
4.313 Impact Factor

3-nitropropionic acid inhibition of succinate dehydrogenase (complex II) activity in cultured Chinese hamster ovary cells: antagonism by L-carnitine.

Ann N Y Acad Sci 2003 May;993:305-12; discussion 345-9

Laboratory of Experimental Neuropathology, Division of Neurotoxicology, National Center for Toxicological Research, USFDA, Arkansas 72079, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2003.tb07538.xDOI Listing
May 2003
18 Reads
4 Citations
4.313 Impact Factor

Adaptation to repeated cocaine administration in rats.

Ann N Y Acad Sci 2002 Jun;965:172-9

Division of Neurotoxicology, NCTR/FDA, Jefferson, Arkansas 72029, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2002.tb04159.xDOI Listing
June 2002
4 Reads
1 Citation
4.313 Impact Factor