Publications by authors named "Zandra Walton"

20Publications

mTOR Senses Intracellular pH through Lysosome Dispersion from RHEB.

Bioessays 2019 07 3;41(7):e1800265. Epub 2019 Jun 3.

Ludwig Institute for Cancer Research, New York, NY, 10017, USA.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/bies.2018002
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http://dx.doi.org/10.1002/bies.201800265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730656PMC
July 2019

Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.

Cell 2018 06 31;174(1):72-87.e32. Epub 2018 May 31.

Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; The Wistar Institute, Philadelphia, PA 19104, USA; Ludwig Institute for Cancer Research, New York, NY 10017, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398937PMC
June 2018

Inflammatory cytokines in major depressive disorder: A case-control study.

Aust N Z J Psychiatry 2017 Jan 29;51(1):23-31. Epub 2016 Sep 29.

1 Center for Anxiety and Traumatic Stress Disorders, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1177/0004867416652736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731241PMC
January 2017

MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.

Cell Metab 2015 Dec 17;22(6):1009-19. Epub 2015 Sep 17.

Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818967PMC
December 2015

MYC, Metabolism, and Cancer.

Cancer Discov 2015 Oct 17;5(10):1024-39. Epub 2015 Sep 17.

Abramson Family Cancer Research Institute, Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592441PMC
October 2015

MYC and metabolism on the path to cancer.

Semin Cell Dev Biol 2015 Jul 12;43:11-21. Epub 2015 Aug 12.

Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2015.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818970PMC
July 2015

Fructose-1,6-bisphosphatase opposes renal carcinoma progression.

Nature 2014 Sep 20;513(7517):251-5. Epub 2014 Jul 20.

1] Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA [2] Howard Hughes Medical Institute, Philadelphia, Pennsylvania 19104, USA [3] Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://www.nature.com/doifinder/10.1038/nature13557
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http://dx.doi.org/10.1038/nature13557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162811PMC
September 2014

Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.

Cancer Cell 2014 May 1;25(5):590-604. Epub 2014 May 1.

Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Belfer Institute For Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.03.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112370PMC
May 2014

Failure to induce apoptosis via BCL-2 family proteins underlies lack of efficacy of combined MEK and PI3K inhibitors for KRAS-mutant lung cancers.

Cancer Res 2014 Jun 27;74(11):3146-56. Epub 2014 Mar 27.

Authors' Affiliations: Massachusetts General Hospital Cancer Center, Charlestown; Department of Medicine, Harvard Medical School; Department of Medical Oncology, Dana-Farber Cancer Institute; and Department of Pathology, Massachusetts General Hospital, Boston, MassachusettsAuthors' Affiliations: Massachusetts General Hospital Cancer Center, Charlestown; Department of Medicine, Harvard Medical School; Department of Medical Oncology, Dana-Farber Cancer Institute; and Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts

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http://dx.doi.org/10.1158/0008-5472.CAN-13-3728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046322PMC
June 2014

ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation.

Cancer Cell 2012 Nov;22(5):631-44

Abramson Family Cancer Research Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.ccr.2012.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510660PMC
November 2012

Target-specific control of lymphoid-specific protein tyrosine phosphatase (Lyp) activity.

Bioorg Med Chem 2010 Jul 12;18(14):4884-91. Epub 2010 Jun 12.

Amherst College, Department of Chemistry, Amherst, MA 01002, United States.

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http://dx.doi.org/10.1016/j.bmc.2010.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915760PMC
July 2010