Publications by authors named "Zahra Moradi"

31 Publications

Prediction and interpretation of rare missense variant in OTOG associated with hearing loss.

Genomics 2021 Jun 9. Epub 2021 Jun 9.

Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran. Electronic address:

OTOG encodes for otogelin, a component of the tectorial membrane. This gene is associated with nonprogressive mild-to-moderate hearing loss. However, no studies have yet identified the association between OTOG variation and severe-to-profound hearing loss. Therefore, to address this issue, a family-based whole-exome sequencing strategy (WES) was carried out. Two unrelated Iranian families with non-syndromic hearing loss were identified, and WES was conducted on one selected candidate from each family. As a result, a rare homozygous missense variant, OTOG (c.C2383T:p.R795C), was detected in both of the subjected probands, and segregation analysis confirmed the c.C2383T variant in seven cases of severe-to-profound hearing loss. Additionally, the results from the protein modeling demonstrated that the altered position of a few disulfide bonds in the TIL domain may have a deleterious impact on protein stability and normal functionality. In conclusion, it seems that the homozygosity of the OTOG c.C2383T mutation sheds light on hearing loss pathobiology. Nevertheless, further studies are required to unravel the precise function of OTOG mutation, which is potentially associated with severe-to-profound hearing loss.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygeno.2021.06.012DOI Listing
June 2021

Association Between Vitamin D Receptor (VDR) and Vitamin D Binding Protein (VDBP) Genes Polymorphisms to Endometriosis Susceptibility in Iranian Women.

Reprod Sci 2021 May 4. Epub 2021 May 4.

Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Endometriosis is a chronic inflammatory disease that has been reported to be associated with immune system dysfunction. On the other hand, the effect of Vitamin D as an immune modulator and its relation with several autoimmune and inflammatory diseases has been previously investigated. Moreover, several studies have reported the polymorphisms of VDR and VDBP genes can change the functions of these molecules. Therefore, these polymorphisms may be influential on endometriosis pathogenesis. In this study, we aimed at evaluating the association between VDR gene (FokI (F/f), BsmI (B/b), ApaI (A/a), TaqI (T/t)), and VDBP gene (GC*1S, GC*1F, and GC*2) polymorphisms with endometriosis in Iranian women population. This case-control study was performed on 120 women with endometriosis and 110 healthy women. ARMS-PCR and PCR-RFLP methods were used to inspect polymorphisms in VDR and VDBP genes, respectively. Based on the results, there was no statistically significant difference between the cases with endometriosis and control subjects in terms of genotypes and allele frequencies of VDR and VDBP gene polymorphisms. These data suggest that VDR and VDBP gene polymorphisms may have no role in endometriosis susceptibility in Iranian women.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1007/s43032-021-00598-zDOI Listing
May 2021

Impact of Ginger Root Powder Dietary Supplement on Productive Performance, Egg Quality, Antioxidant Status and Blood Parameters in Laying Japanese Quails.

Int J Environ Res Public Health 2021 03 15;18(6). Epub 2021 Mar 15.

CBIOS (Research Center for Biosciences and Health Technologies), Universidade Lusófona de Humanidades e Tecnologias, Campo Grande 376, 1749-024 Lisboa, Portugal.

Medicinal plants with antibacterial effects have been used by humans for centuries. In the recent decade, due to the development of antibiotic resistant strains, many studies have focused on the use of natural compounds as feed additives in livestock. Ginger, among all, have repetitively shown numerous biological activities, antibacterial, and antibiotic properties. This study was conducted to evaluate the effects of ginger root powder (GP) on the performance, egg quality, and blood parameters of Japanese quail. A total of 240 10-weeks old female quails were used in a completely randomized design with 4 treatments, 4 replicates, and 15 birds per replicate. Dietary treatment were basal diet (control) and basal diet containing 0.5, 1, and 1.5 g/kg of ginger root powder. Growth performance and exterior and interior quality of egg were measured biweekly over eight-week period. At the end of experiment blood parameters were evaluated. The results showed that diet supplementation with different levels of GP had no significant effect on egg production, egg mass weight, and egg weight ( > 0.05). However, feed intake and feed conversion ratio were significantly lower in the treatment group than the control in the whole period ( < 0.05). Egg Quality traits (shape index, albumen index, the percentage of albumen, yolk and shell, yolk pH, and shell thickness and strength) were not affected by the supplements in the whole trial period. Addition of GP significantly increased the albumen height, Haugh unit, and albumen pH in comparison with the control treatment ( < 0.05). GP reduced blood triglyceride level yet was ineffective on blood total antioxidant capacity and malondialdehyde. In conclusion, dietary supplementation with GP, could improve productive performance and the egg quality of Japanese quails. Nonetheless a comprehensive study needs to be performed in order to evaluate the impact of quail dietary ginger supplementation on productive performance and egg quality and their stability during storage time for commercial use.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijerph18062995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001588PMC
March 2021

The effects of resveratrol on the expression of VEGF, TGF-β, and MMP-9 in endometrial stromal cells of women with endometriosis.

Sci Rep 2021 Mar 15;11(1):6054. Epub 2021 Mar 15.

Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Resveratrol is a phytochemical with anti-angiogenic, anti-inflammatory, and antioxidant properties. The present study has evaluated the effect of resveratrol on the expression of vascular endothelial growth factor (VEGF), transforming growth factor-β (TGF-β) and matrix metalloproteinase-9 (MMP-9) as factors related to endometriosis progression. Thirteen eutopic (EuESCs) and 8 ectopic (EESCs) endometrial stromal cells from women with endometriosis and 11 control endometrial stromal cells (CESCs) were treated with resveratrol (100 µM) for 6, 24 and 48 h. The gene and protein expression levels of VEGF, TGF-β, and MMP-9 were measured using real-time PCR and ELISA methods, respectively. Results showed that the basal gene and protein expression of VEGF and MMP-9 were higher in EESCs compared to EuESCs and CESCs (P < 0.01 to  < 0.001 and P < 0.05 to  < 0.01 respectively). Also, resveratrol treatment decreased the gene and protein expression of VEGF and MMP-9 in EuESCs, EESCs and CESCs (P < 0.05 to  < 0.01 and P < 0.05 to  < 0.01 respectively) and gene and protein expression of TGF-β in EESCs and EuESCs (P < 0.05 to  < 0.01). The effect of resveratrol in reduction of VEGF gene expression was statistically more noticeable in EESCs compared to EuESCs and CESCs (P < 0.05). According to the findings, resveratrol may ameliorate endometriosis progression through reducing the expression of VEGF, TGF-β, and MMP-9 in endometrial stromal cells (ESCs).
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-021-85512-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961000PMC
March 2021

Evaluating the effect of an educational program on increasing cervical cancer screening behavior among women in Fasa, Iran.

BMC Womens Health 2021 01 28;21(1):41. Epub 2021 Jan 28.

No Communicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.

Background: Cervical cancer is the second most common cancer and the fifth deadliest cancer among women in Iran. Educational interventions based on the proper behavior promoting models can lead to early diagnosis of cervical cancer.This study aimed to investigate the effects of educational intervention on performing Pap smear tests based on the Theory of Planned Behavior among women living in Fasa, Iran.

Methods: A cross-sectional study was conducted on 700 participants. Thereafter, the educational intervention based on the results of cross-sectional study was conducted in a workshop form for 50 women as the intervention group and 50 women as the control group. Afterward, the data were entered into the SPSS statistical software and then analyzed via logistic regressions analysis, paired t test, independent t test, chi-square test, and McNemar test.

Result: According to the results, 45.7% of the patients had a history of performing a Pap smear test, and 20.7% of them regularly performed this test. The knowledge, attitude, subjective norms, and perceived behavioral control were the predictors of intention and behavior of Pap smear test among the women (P < 0.05). These components accounted for 57.4% and 31.6% of the intention and behavior variances, respectively. After the intervention, a significant increase was observed in the means of attitude, subjective norms, and perceived behavioral control in the intervention group compared to the control group. The results reveal no significant difference between these two groups regarding the behavioral intention (p = 0.41) and performance of the Pap smear test (p = 0.583). The number of the participants undergone the Pap smear test has increased from 10 to 26 in the intervention group by passing 3 months from the intervention. The results of McNemar test indicated that this difference was statistically significant.

Conclusion: The results indicated an increase in the women's performance of the Pap smear screening test by appropriate planning, provision of educational packages based on the women's needs, and using effective subjective norms.

Trial Registration: Current Controlled Trials IRCT20160830029608N3:12/31/2018. "Retrospectively registered".
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12905-021-01191-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844982PMC
January 2021

Vitamin D deficiency as a risk factor for endometriosis in Iranian women.

J Reprod Immunol 2021 02 17;143:103266. Epub 2020 Dec 17.

Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Electronic address:

Purpose: Vitamin D (Vit D), as an immunomodulator, has been hypothesized to play a critical role in the pathogenesis of endometriosis. Thus, in this study, we evaluated whether there is an association between 25-hydroxyvitamin D [25(OH)D] and susceptibility to endometriosis in Iranian women.

Methods: Women at reproductive age, including 56 healthy women and 54 patients with endometriosis, were enrolled in the study. Serum levels of 25(OH)D, calcium, parathyroid hormone (PTH), and peritoneal fluid (PF) levels of 25(OH)D were assessed.

Results: The serum and PF levels of 25(OH)D in the patients with endometriosis were significantly lower than the control group (P = 0.001 and P = 0.03, respectively). Subjects with serum levels of 25(OH)D lower than 20 ng/mL had a 2.7 times higher risk of endometriosis than people with 25(OH)D serum levels higher than 20 ng/mL (non-deficient) (OR = 2.7, 95 % confidence interval: 1.24-5.80, P = 0.01). The serum levels of calcium and PTH were significantly lower and higher in patients with endometriosis compared with controls, respectively (P < 0.001, P = 0.02, respectively). Also, the serum levels of 25(OH)D were lower in stages I-II endometriosis than stage III-IV; however, no significant difference was observed.

Conclusion: Our findings showed that people with Vit D deficiency are at higher risk of endometriosis.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jri.2020.103266DOI Listing
February 2021

The effects of exposure to different noise frequency patterns on blood pressure components and hypertension.

Int Arch Occup Environ Health 2020 Nov 6;93(8):975-982. Epub 2020 May 6.

Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Objective: Previous studies have indicated a significant association between exposure to noise and blood pressure. However, the effects of exposure to different noise frequency patterns on blood pressure components and hypertension (HTN) have been unknown.

Methods: We recruited a total of 518 eligible workers in this study. According to types of work (office and production-line), overall A-weighted equivalent sound pressure levels (8-h LAeq), and total 8-h LAeq at low (31.5, 63, and 125 Hz), medium (250, 500, and 1000 Hz), and high ( 2, 4, and 8 kHz) frequencies, we classified subjects into four categories, involving office workers (n = 214) exposed to overall 8-h LAeq < 65 dB and production-line workers, including medium noise exposure group (n = 81) exposed to overall 8-h LAeq < 78 dB that difference between the medium and high frequencies was less than 1 dB, high_A noise exposure group (n = 86) encountered to overall 8-h LAeq > 90 dB that the difference between the medium and high frequencies was less than 1 dB, and high B noise exposure group (n = 137) exposed to overall 8-h LAeq > 90 dB that the levels of noise at the high frequency were 10 dBA more than the medium frequency. The high A and high B groups were a little difference in total 8-h LAeq at the low and medium frequencies (≤ 3 dBA) and a wide difference at the high frequency (more than 10 dBA). The logistic regression models were applied to determine the odds of HTN among study groups.

Results: The significant difference was observed among study groups in the average of systolic blood pressure (SBP), pulse pressure (PP), mean arterial pressure (MAP), and the frequency of HTN (P < 0.05). Also, we found a significant difference in diastolic blood pressure DBP but at the levels of P < 0.10. The odds ratios (ORs) and 95% confidence intervals (CIs) of HTN according to the full adjusted model in the medium, high A, and high B groups compared with the office workers were estimated at 1.66(0.45, 6.10), 2.34(0.80, 6.89), and 4.02(1.63, 9.96), respectively.

Conclusion: This study indicates noise frequency patterns may play a significant role in the association between noise and blood pressure. More studies are warranted to confirm our findings.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00420-020-01545-2DOI Listing
November 2020

Morphological and physical properties of kefiran-whey protein isolate bionanocomposite films reinforced with AlO nanoparticles.

Authors:
Zahra Moradi

Food Sci Technol Int 2020 Dec 1;26(8):666-675. Epub 2020 May 1.

Department of Food Science and Technology, Faculty of Agriculture, Urmia University, Urmia, Iran.

Considering environmental pollution caused by the non-biodegradable polymers used in food packaging, developing and enhancing the properties of biodegradable films seem to be necessary. For this aim, in the present study, kefiran-whey protein isolate bionanocomposite films were prepared and the impact of different concentrations (1, 3 and 5% w/w) of AlO (alumina) nanoparticles on their physical, morphological, thermal and mechanical properties was studied. Based on the obtained results, an increase in the nanoparticles content led to a significant decrease (p < 0.05) in the water vapor permeability, moisture absorption, moisture content, and water solubility. Scanning electron microscope images showed a homogeneous structure, confirming the good dispersion of alumina nanoparticles with smooth surface up to concentration of 3%. In addition, both thermal stability and mechanical properties of the films were improved by the increased concentrations of alumina. The results of X-ray diffraction indicated that the intensity of the crystalline peaks of film increased with the addition of AlO to kefiran-whey protein isolate matrix. By considering all results, the concentration of 3% was proposed as the appropriate concentration of AlO for the nano-reinforcement of kefiran-whey protein isolate bionanocomposites.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1177/1082013220921599DOI Listing
December 2020

The Association of Occupational Noises and the Prevalence of Metabolic Syndrome.

Ann Work Expo Health 2020 06;64(5):514-521

Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Objectives: Previous studies have shown the association of exposure to noise with cardiovascular diseases such as hypertension, however, it is not well known whether the exposure has any effect on metabolic syndrome (MetS). This study aimed to quantify and clarify the association between noise exposure and the prevalence of MetS.

Methods: This cross-sectional study was conducted in 2017 among 518 workers in a thermal power plant industry. According to types of work and 8-h equivalent A-weighted sound pressure level (8-h LAeq), the participants were divided into the following groups: office workers and line-production workers exposed to < 85, 90 to <95, 95 to <100, and ≥100 dBA. We used the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) criteria to identify subjects with MetS. The logistic regression was used to determine the odds of MetS among study groups.

Results: We observed the significant differences in the number (%) of subjects with high blood pressure in line-production workers who exposed to noise ≥100 (12 [19.7%]) versus <85 dBA (7 [7.1%]) and office (10 [4.7%]) groups. For the waist circumference (>102 cm), there was a significant difference in the ≥100 dBA group (12 [19.7%]) compared with office group (21 [9.8%]). Obtained results indicated only the significant difference in the prevalence of MetS in ≥100 versus <85 dBA groups (10 [16.4%] versus 6 [6.1%]). The unadjusted and adjusted odds ratios and 95% confidence intervals of MetS in ≥100 versus <85 dBA groups were estimated 3.01 (1.03, 8.75) and 3.24 (1.01, 10.42), respectively.

Conclusions: This study indicated the significant association between noise exposure and MetS in line-production workers. However, more studies are needed to confirm our results.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1093/annweh/wxaa030DOI Listing
June 2020

Higher frequency of circulating, but not tissue regulatory T cells in patients with endometriosis.

J Reprod Immunol 2020 06 18;139:103119. Epub 2020 Mar 18.

Reproductive Immunology Research Center, Avicenna Research Institute, ACECR, Tehran, PO Box: 19615-1177, Iran; Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Background: Endometriosis is one of the most common chronic gynecological disorders affecting women at reproductive age. Dysregulation of immune cells, including regulatory T (Treg) cells has contributed to the growth of ectopic lesion in patients with endometriosis.

Objective: The present study investigated the frequency of Tregs in peripheral blood and the expression of Foxp3 in eutopic and ectopic endometriotic tissues in women with and without endometriosis.

Materials And Methods: Peripheral blood mononuclear cells (PBMCs) and eutopic and ectopic endometriotic tissues were obtained from 23 endometriotic and 20 non-endometriotic control women. The frequency of Treg cells in PBMCs was measured using flowcytometry and the expression of Foxp3 in eutopic and ectopic endometriotic tissues was determined by real-time PCR, western blotting and immunohistochemistry.

Result: The frequency of circulating Tregs was significantly higher in endometriotic patients compared with non-endometriotic controls (P < 0.01). The mRNA and protein expression of Foxp3 in eutopic and ectopic endometriotic tissues had no significant differences between the two study groups.

Conclusion: Higher frequency of circulating Tregs in patients with endometriosis compared with controls may be considered as a compensatory mechanism to regulate the inflammatory condition in this disease.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jri.2020.103119DOI Listing
June 2020

Updates on Novel Erythropoiesis-Stimulating Agents: Clinical and Molecular Approach.

Indian J Hematol Blood Transfus 2020 Jan 16;36(1):26-36. Epub 2019 Sep 16.

6Faculty of Allied Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.

Erythropoietin (EPO) is an important hormone responsible for the stimulation of hematopoiesis which is impaired in a variety of diseases, such as chronic kidney disease, cancer chemotherapy, and the use of some anti-HIV drugs. Difficulties in the purification of endogenous EPO due to problems such as technical limitations, heterogeneity of target cells, inadequate amount and immunogenicity of the resultant product, had limited the entry of endogenous EPO in the clinical applications. The integration of medical biotechnology and hematology has introduced novel procedures for the production of human recombinant erythropoietin (rHuEPO), and other erythropoiesis-stimulating agents (ESAs). To investigate and produce rHuEPO, the first step is to recognize the molecular biology and functional pathways, structure, metabolism, and basic physiology of EPO. In this review, all clinical indications, side effects, challenges and notable points regarding EPO, rHuEPO, and other ESAs have also been addressed along with its molecular characterization, such as the modifications needed to optimize their rHuEPO biosynthesis.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12288-019-01170-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042474PMC
January 2020

The comparison of plasma fibronectin in term and preterm delivery: A cross-sectional, descriptive-analytical study.

Int J Reprod Biomed 2019 Apr 27;18(1):11-20. Epub 2020 Jan 27.

School of Nursing, Fasa University of Medical Sciences, Fasa, Iran.

Background: Preterm delivery is one of the main causes of infant death. Therefore, prediction of preterm delivery may eliminate a large number of prenatal complications.

Objective: The present study aimed to understand if preterm delivery can be predicted by assessing maternal plasma fibronectin concentration.

Materials And Methods: Serum samples from 105 pregnant women participating in this study were collected. The plasma fibronectin were measured at 24-28 wk of gestation and again at 32-36 wk of gestation. Unfortunately, only 65 of the 105 pregnant women, returned for the second sampling. The plasma fibronectin was analyzed using ELISA method and its concentration in term and preterm deliveries was compared. The delivery dates of all the women were also recorded.

Results: Out of 105 pregnant women, 28 delivered preterm (26.7%). The Plasma fibronectin concentrations in women with preterm delivery were higher than in those who delivered at term (p = 0.001). Accordingly, Plasma fibronectin concentrations were significantly higher in the second serum samples (p = 0.01). Plasma fibronectin concentrations was also higher in obese women and in those suffering from preeclampsia (p = 0.12) and gestational diabetes (p = 0.81).

Conclusion: Plasma fibronectin concentrations test could be used as an optional screening test for preterm delivery at 28 to 34 wk of gestation in pregnant women who prefer to avoid vaginal sampling.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.18502/ijrm.v18i1.6191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996127PMC
April 2019

Attentional saliency and ingroup biases: From society to the brain.

Soc Neurosci 2020 06 17;15(3):324-333. Epub 2020 Jan 17.

Department of Experimental Psychology, University of Oxford , Oxford, England, UK.

There is ample evidence demonstrating intergroup biases on cognition and emotion. However, it remains unclear how exactly group identification influences these processes, with issues of context sensitivity and goal dependence remaining open to scrutiny. Providing a range of interdisciplinary material, the current review attempts to inform understanding of these issues. Specifically, we provide evidence revealing that individuals show enhanced attention for stimuli associated with an ingroup compared to an outgroup. At the attentional level, such biases can be explained by the assignment of different levels of saliency to ingroup versus outgroup targets. Critically, however, salience assignment is not fixed but varies as a function of context and goal-directed behavior. We suggest that the network in the brain previously associated with social and emotional saliency and attention - notably the anterior insula, posterior superior temporal sulcus, and dorsolateral prefrontal cortex - underpins these effects. Moreover, although attention typically favors ingroup targets, outgroup members can be prioritized on occasion. The implications of this viewpoint and future lines of investigation are considered.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1080/17470919.2020.1716070DOI Listing
June 2020

Comparison of the Effects of Lidocaine-Prilocaine Cream and Lidocaine Injection on the Reduction of Perineal Pain While Doing and Repairing Episiotomy in Natural Vaginal Delivery: Randomized Clinical Trial.

Anesth Pain Med 2019 Jun 24;9(3):e90207. Epub 2019 Apr 24.

Nursing School, Fasa University of Medical Sciences, Fasa, Iran.

Background: Doing and repairing episiotomy in a natural vaginal delivery is a painful phenomenon and various methods have been used to reduce its pain. Nowadays, topical ointments are being increasingly used due to low systemic absorption and ease of use.

Objectives: The present study aimed to compare the effects of lidocaine-prilocaine cream (XYLA cream) and lidocaine injection on the reduction of pain while doing and repairing episiotomy.

Methods: This randomized clinical trial was conducted on 98 pregnant women with the gestational age of > 37 weeks. In the intervention group that contained 50 women, 5 gr XYLA cream was applied to the episiotomy area one hour prior to delivery. It was also applied to healthy wound edges to numb the area while repairing episiotomy. In the control group, lidocaine 2% injection was used at the time of delivery. The two groups were compared regarding demographic characteristics, delivery characteristics, pain intensity based on visual analogue scale (VAS), and satisfaction with the applied technique.

Results: The results showed no significant differences between the two groups with respect to age, occupation, mother's weight and education level, gestational age, parity, number of deliveries, and infant's weight and head circumference (P > 0.05). Also, no significant difference was found between the two groups concerning the length of the active, second, and third phases of labor (P > 0.05). Considering postpartum complications (episiotomy wound infection), the infection was detected in three participants in the XYLA cream group and four individuals in the lidocaine group, but the difference was not statistically significant (P = 0.376). It should be noted that the application of XYLA cream did not cause eye irritation in any of the infants. The results also revealed no significant differences between the two groups regarding pain intensity and satisfaction with the applied technique after doing and repairing episiotomy (P = 0.288).

Conclusions: The results indicated that XYLA cream had no specific complications and had an effect similar to lidocaine injection while doing the episiotomy.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.5812/aapm.90207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717320PMC
June 2019

Kefiran, a branched polysaccharide: Preparation, properties and applications: A review.

Carbohydr Polym 2019 Nov 19;223:115100. Epub 2019 Jul 19.

Department of Nanochemistry, Nanotechnology Research Centre, Urmia University, Urmia, 5756151818, Iran. Electronic address:

Considering harmful effects of the environmental pollution and increased concerns about the synthetic polymers, kefiran has been introduced as a biodegradable polymer due to its nontoxicity. This edible biopolymer and its structural derivations play specific roles in a large number of applications including scaffolds, the reserve materials, and the encapsulation for drug delivery, thanks to its amazing properties such as the protective features, the bifidogenic effects and the antimicrobial activity against some microorganisms. The aim of the present review was to focus on the methods of producing kefiran, its properties and finally its applications, bringing significant changes in various fields.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carbpol.2019.115100DOI Listing
November 2019

The effects of exposure to different noise frequencies on the prevalence of metabolic syndrome.

Eur J Prev Cardiol 2020 09 30;27(13):1451-1454. Epub 2019 Jul 30.

Student Research Committee, Kermanshah University of Medical Sciences, Iran.

View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1177/2047487319866988DOI Listing
September 2020

The effect of narrative writing on fathers' stress in neonatal intensive care settings.

J Matern Fetal Neonatal Med 2021 Feb 16;34(3):403-408. Epub 2019 Jun 16.

School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.

This study was conducted to examine the effect of narrative writing on fathers' stress in the Neonatal Intensive Care Units (NICUs) during infants' hospitalization. A quasi-experimental study was conducted among two groups of fathers with preterm infants in the NICUs of two teaching hospitals of Gorgan University of Medical Sciences. Pre- and post-tests were administered to a sample size of 70 during 6 months. The Parental Stressor Scale (PSS) was used. The data were analyzed using descriptive and analytical statistical methods. The mean total stress score was 74.05 ± 17.39 in the control and 80.11 ± 15.82 in the intervention group on the 3rd day, suggesting no significant difference. In other words, both groups had a similar stress level before the intervention (-value = .13,  = 1.52). However, the mean total stress score was 85.45 ± 16.91 in the control group and 48.00 ± 10.49 in the intervention group on the 10th day, suggesting a significant reduction in the stress level in the intervention group following the intervention (-value = .001, = -11.01). According to the findings, the narrative writing may be considered as an efficient supportive intervention to reduce the fathers' stress in the NICUs. However, more research is needed to justify its implementation.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1080/14767058.2019.1609926DOI Listing
February 2021

Perceptions and practices related to clinical alarms.

Nurs Forum 2019 Jul 5;54(3):369-375. Epub 2019 Mar 5.

Department of Anesthesia and Operating Room Nursing, Neyshabur University of Medical Sciences, Neyshabur, Iran.

Background: Clinical alarms represent the top hazard listed in the "Top Ten Health Technology Hazards" report. Frequent false alarms can disrupt patient care and reduce trust in alarms.

Aim: The aim of the present study was to investigate the perceptions and practices of critical and noncritical care nurses regarding clinical alarms.

Methodology: This was a descriptive analytical study conducted from October 2016 to February 2017 at three hospitals on 197 nurses at Neyshabur University of Medical Sciences in Neyshabur, Northeastern Iran. Participants were selected through stratified random sampling. The perceptions were measured through the 2011 Health care Technology Foundation Clinical Alarms Survey.

Results: More than half of the nurses believed that frequent false alarms reduced trust in alarms, leading nurses to inappropriately disable alarms. The nurses ranked frequent false alarms as the most important issue in response to alarms. More than 60% of the nurses indicated that they needed more training on the use of bedside and central monitors.

Conclusion: The result of this study suggested that frequent false alarms, as the most important issue related to alarms, should be taken into account by hospital administrators and researchers to decrease alarm fatigue and improve alarm system safety. More specialized clinical policies and procedures for alarm management should also be considered.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1111/nuf.12338DOI Listing
July 2019

Development and characterization of kefiran - AlO nanocomposite films: Morphological, physical and mechanical properties.

Int J Biol Macromol 2019 Feb 30;122:603-609. Epub 2018 Oct 30.

Department of Food Science and Technology, Faculty of Agriculture, P.O. Box 57561-51818, Urmia University, Urmia, Iran. Electronic address:

Biodegradable kefiran films, containing different concentrations of AlO (alumina) (1, 3 and 5% w/w), were prepared by casting method and their physical, mechanical, and thermal properties were studied. Based on the results, the increase of the nano-AlO content led to a decrease in the water vapor permeability, moisture content, moisture absorption, and water solubility. The addition of nanoparticles did not affect the lightness of the films significantly (P > 0.05). The mechanical tests revealed that the addition of AlO nanoparticles to the kefiran films significantly increased both tensile strength and elastic modulus, while had no effect on the elongation at break (P > 0.05). Thermogravimetric analysis (TGA) indicated the improvement of the films' thermal stability by adding alumina. The results of X-ray diffraction (XRD) confirmed the effect of AlO on the semi-crystalline structure of kefiran. Scanning electron microscopy (SEM) images approved a uniform distribution of nanocomposites containing 1 and 3% w/w of AlO. The obtained results suggested that AlO was able to improve the characteristics of the kefiran-based films for using as food packaging material.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijbiomac.2018.10.193DOI Listing
February 2019

Comparison of the effect of narrative writing and art therapy on maternal stress in neonatal intensive care settings.

J Matern Fetal Neonatal Med 2020 Feb 23;33(4):664-670. Epub 2018 Sep 23.

Department of Nursing, Neyshabur University of Medical Sciences, Neyshabur, Iran.

This study was conducted to examine the effect of narrative writing and art therapy on maternal stress in the neonatal intensive care units (NICUs) during infants' hospitalization. randomized controlled clinical trial with three parallel arms study was conducted among three groups of mothers with preterm infants in the NICUs of two teaching hospitals of Shahroud University of Medical Sciences. Pre- and post-tests were administered to a sample size of 105 during 9 months. The parental stressor scale (PSS) was used. The data were analyzed using descriptive and analytical statistical methods. The mean maternal stress score was 54.94, 47.08, and 47.57 in the art therapy, narrative writing, and control before the intervention respectively, indicating no significant difference between the groups ( = .28). There was also no significant difference in the mean score of stress between the groups after the intervention ( = .92). Also, we found no significant difference in the mean score of parental role and parents' relationship and sights and sounds between the three groups on the second day ( = .22 and  = .12, respectively) but there was a significant difference in the mean score of infant behavior and appearance between the three groups ( = .05). There was no significant difference in parental role and parents' relationship ( = .31), infant behavior and appearance ( = .58), and sights and sounds ( = .67) between the three groups on the sixth day of intervention. Narrative writing and art therapy are only effective on the subscale of infant behavior and appearance in the PSS: NICU.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1080/14767058.2018.1499719DOI Listing
February 2020

In-group biases and oculomotor responses: beyond simple approach motivation.

Exp Brain Res 2018 05 7;236(5):1347-1355. Epub 2018 Mar 7.

Cognitive Neuropsychology Centre, Department of Experimental Psychology, University of Oxford, New Radcliffe House, Walton Street, Oxford, OX2 6AE, UK.

An in-group bias describes an individual's bias towards a group that they belong to. Previous studies suggest that in-group bias facilitates approach motor responses, but disrupts avoidance ones. Such motor biases are shown to be more robust when the out-group is threatening. We investigated whether, under controlled visual familiarity and complexity, in-group biases still promote pro-saccade and hinder anti-saccades oculomotor responses. Participants first learned to associate an in-group or out-group label with an arbitrary shape. They were then instructed to listen to the group-relevant auditory cue (name of own and a rival university) followed by one of the shapes. Half of the participants were instructed to look towards the visual target if it matched the preceding group-relevant auditory cue and to look away from it if it did not match. The other half of the participants received reversed instructions. This design allowed us to orthogonally manipulate the effect of in-group bias and cognitive control demand on oculomotor responses. Both pro- and anti-saccades were faster and more accurate following the in-group auditory cue. Independently, pro-saccades were performed better than anti-saccades, and match judgements were faster and more accurate than non-match judgements. Our findings indicate that under higher cognitive control demands individuals' oculomotor responses improved following the motivationally salient cue (in-group). Our findings have important implications for learning and cognitive control in a social context. As we included rival groups, our results might to some extent reflect the effects of out-group threat. Future studies could extend our findings using non-threatening out-groups instead.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00221-018-5221-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937882PMC
May 2018

Association of CD46 IVS1-1724 C>G Single Nucleotide Polymorphism in Iranian Women with Unexplained Recurrent Spontaneous Abortion (URSA).

Iran J Allergy Asthma Immunol 2016 Aug;15(4):303-308

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran AND Department of Immunology, Tabriz University of Medical Sciences, Tabriz, Iran.

There are several known and unknown factors for unexplained recurrent spontaneous abortion (URSA). Among them, complement regulatory protein CD46 plays a pivotal role in preventing uncontrolled activation of complement and successful continuation of pregnancy. We aimed in this study to investigate the possible association of CD46 IVS1-1724 C>G polymorphism with RSA in Iranian women. 141 women with RSA and 153 women with normal pregnancy were enrolled in this study. RSA was confirmed as the history of having at least three consecutive abortions without any known immunologic, pathologic and genetic reason. Genomic DNA was extracted and RFLP-PCR was done using a specific primer pair and HindIII restriction enzyme. Statistical analysis was done for determining the genotype and allele frequency, and also for odds ratio (OR). Statistical analysis showed no significant difference in genotype frequency between two RSA and normal groups. However G allele was significantly more frequent in fertile women and represented as a protective allele (p=0.04, OR=0.8, CI 95%). In contrary to similar studies in other two ethnic populations, our study showed no genotype differences in CD46 IVS1-1724 C>G Single nucleotide polymorphis (SNP) between RSA and fertile women. On the other hand, G allele was revealed as a protective allele for RSA. CD46 polymorphisms may predict the outcome of pregnancy; however, more studies in different ethnic groups are required.
View Article and Find Full Text PDF

Download full-text PDF

Source
August 2016

Avicenna's View on the Etiologies of Intestinal Obstruction.

Iran Red Crescent Med J 2016 Feb 1;18(2):e20034. Epub 2016 Jan 1.

Department of Gastroenterology, Tehran University of Medical Sciences, Tehran, IR Iran.

Context: Bowel obstruction is one of the most common causes of acute abdomen. Because of heterogeneity of patients' population and variety of causes, therapeutic strategies are not standardized, so treatment of intestinal obstruction is a surgical challenge in many cases. A traditional medicine approach could help detect some issues that were ignored by modern medicine. One of the major schools of medicine, with a history of several thousand years, is Iranian traditional medicine. In this regard, Avicenna, who lived in the medieval period, has had a great influence on the medical knowledge of the world by writing an encyclopedia of medicine entitled "Qanun of Medicine."

Evidence Acquisition: The aim of this study was to investigate Avicenna's views on the causes of intestinal obstruction and comparing them to modern medicine views. This is a review study on an Iranian traditional textbook of medicine by Avicenna, entitled "Qanun of Medicine" (in short "Qanun"). We used Qanun in its original language (Arabic) along with its Persian translation. It consists of 5 books. Part 16 of the third book talks about intestinal anatomy and introduces some intestinal diseases such as "qoolinj" and "ilavos." Intestinal obstruction can be a kind of "qoolinj" or "ilavos" disease. All intestinal obstruction etiologies in Qanun are searched in international and Iranian databases (Scopus, ISI, SID, and Iranmedex) and similar causes in modern medicine will be discussed in this article.

Results: According to Qanun, 16 causes are involved in intestinal etiologies of bowel obstruction such as "reeh," mucoid phlegm, abdominal hot and dry distemperament, decreased bile secretion, job, and so on while modern medicine considers some of them, for instance, volvulus, intestinal herniation, worm, intestinal pseudo-obstruction, and opiate.

Conclusions: Attention to the similar causes of intestinal obstruction in modern medicine and traditional medicine is the starting point for investigation of noninvasive diagnostic and therapeutic methods that have been mentioned in Qanun. In addition, etiologies which are missed in modern medicine can open new doors to the researchers and gastroenterologists for the study, diagnosis, and prevention of the disease.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.5812/ircmj.20034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860500PMC
February 2016

Analysis of survival data in thalassemia patients in Shiraz, Iran.

Epidemiol Health 2015 7;37:e2015031. Epub 2015 Jul 7.

Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.

Objectives: The survival rate of thalassemia patients has not been conclusively established, and the factors associated with survival remain unclear. This study aimed to determine the survival rate of thalassemia among patients in southern Iran and to identify the factors associated with mortality from thalassemia.

Methods: This retrospective cohort study was conducted based on a retrospective review of the medical records of 911 beta-thalassemia patients in 2014. Data analysis was conducted using the Kaplan-Meier method and Cox regression analysis.

Results: Overall, 212 patients (23.3%) died, and 26.8% had thalassemia intermedia. The 20-year, 40-year, and 60-year survival rates were 85%, 63%, and 54%, respectively. Both crude and adjusted analyses found that education, marital status, ferritin levels, and comorbidities were related to mortality.

Conclusions: Sociodemographic and hematological factors were found to be significantly associated with the survival rate of thalassemia. Addressing these factors may help healthcare providers and physicians to provide the best possible care and to improve the survival rate.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.4178/epih/e2015031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616013PMC
October 2015

Effect of burn sites (upper and lower body parts) and gender on extensive burns' mortality.

Iran J Med Sci 2015 Mar;40(2):166-9

Shiraz Burn Research Center, Ghotbedin Burn Hospital, Shiraz University of Medical Sciences, Shiraz, Iran;

Our recent literature survey indicated a lack of clinical assessment of the influence of gender and site of burn injury on the outcome of patients with extensive burns. This report examines the effect of burn sites and gender on extensive burns' mortality. Data was gathered from 283 patients with burns larger than 65% of the total body surface area (TBSA) above the belt line or below the belt line; and without underlying diseases and inhalation burn injury. Patients were classified according to gender, site of injury (upper and lower body parts) and hospital stay period. Mortality rates of each category were then compared with each other. The hospital stay period in the female group was significantly higher compared with the male group (P<0.001) and the mortality rate among the female patients was higher compared with the male patients (P=0.004). Although the mortality rate in lower body part of the male group was significantly higher in comparison with the upper body part burn (P=0.001), there was no difference in mortality rate of upper versus lower body part in the female group. The mortality rate was generally higher among the female patients. Additionally, higher mortality rate was observed among male patients with lower body part burn compared with injuries of male patients with upper body part burn.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359937PMC
March 2015

Production and Purification of a Polyclonal Antibody Against Purified Mouse IgG2b in Rabbits Towards Designing Mouse Monoclonal Isotyping Kits.

Adv Pharm Bull 2015 Mar 5;5(1):109-13. Epub 2015 Mar 5.

Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.

Purpose: Mouse IgG subclasses containing IgG1, IgG2a, IgG2b and IgG3 have been defined and described both physiochemically and immunologically.

Methods: Sepharose beads conjugated with protein A affinity chromatography was used for purification of mouse IgG2b. Sodium citrate buffer (0.1 M, pH: 3.5) was used for separation of mouse IgG2b. Verification of the purified fractions was monitored by SDS-PAGE (polyacrylamide gel electrophoresis) in reducing condition. Immunized rabbit serum was collected and precipitated at the final concentration of 50% ammonium sulfate. After dialysis against tris-phosphate buffer (pH: 8.1) ion exchange chromatography column was used for purification of rabbit anti-mouse IgG2b. The periodate method was performed for conjugation with some variations. After conjugation, direct ELISA was used to determine the titer of HRP conjugated rabbit IgG against mouse IgG2b.

Results: The titer of rabbit anti-mouse IgG2b that determined by ELISA was 32000. The purity of rabbit anti-mouse IgG2b was about 95%. The optimum dilution of prepared HRP conjugated IgG was 1:10000. This study showed that ion-exchange chromatography and affinity chromatography could be appropriate techniques for purification of mouse IgG and IgG subclasses respectively.

Conclusion: This study showed that affinity chromatography could be an appropriate method for purification of IgG2b antibodies.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.5681/apb.2015.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352212PMC
March 2015

The Effect of Acupressure at GB-21 and SP-6 Acupoints on Anxiety Level and Maternal-Fetal Attachment in Primiparous Women: a Randomized Controlled Clinical Trial.

Nurs Midwifery Stud 2014 Sep 20;3(3):e19948. Epub 2014 Sep 20.

Department of Physical Medicine and Rehabilitation, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran.

Background: Delivery is one of the most stressful events in women's life. Excessive anxiety, in turn, increases delivery and pregnancy complications. Mother's positive experience of delivery leads to more effective maternal-fetal attachment in the first few hours of birth.

Objectives: The present study aimed to compare the effects of acupressure at two different acupoints on anxiety level and maternal-fetal attachment in primiparous women.

Materials And Methods: In this study, 150 primiparous women were allocated to acupressure at GB-21 acupoint, acupressure at SP-6 acupoint, and control group. The women in their active phase of delivery were enrolled in the study and pressure was applied to the acupoints for 20 minutes. Mother's anxiety level was assessed using Spielberger's questionnaire before and one hour after the intervention. In addition, maternal-fetal attachment behaviors were evaluated using Avant's questionnaire during the first breastfeeding. Then the data were introduced to the SPSS (v. 13) and were analyzed using t test and one way ANOVA.

Results: The results revealed no significant difference among the three groups regarding the anxiety level before the intervention (P > 0.05). One hour after the intervention, this measure was significantly lower in the intervention groups in comparison to the control group (P < 0.001). However, no significant difference was found between the two intervention groups in this regard (P > 0.05). Moreover, maternal-fetal attachment was higher in the intervention groups in comparison with the control group (P < 0.001).

Conclusions: Acupressure at both acupoints reduced anxiety level and increased maternal-fetal attachment. This method can be easily used in the delivery room.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332991PMC
http://dx.doi.org/10.17795/nmsjournal19948DOI Listing
September 2014

Comparison of respiratory muscles activity and exercise capacity in patients with idiopathic scoliosis and healthy individuals.

Physiother Theory Pract 2014 Nov 22;30(8):552-6. Epub 2014 Jul 22.

Department of Physical Therapy, Iran University of Medical Sciences , Tehran , Iran.

Purpose: Idiopathic scoliosis causes respiratory muscles weakness and reduced exercise capacity. However, the mechanism of these symptoms is still unknown. The main objective of this study was to determine the intensity of respiratory muscle activity and exercise capacity in patients with idiopathic scoliosis in comparison with healthy people.

Subjects: In this study, 20 female patients with adult idiopathic scoliosis (10 mild and 10 moderate) as well as 10 healthy matched individuals with characteristics of the patients were selected.

Methods: The subjects were fatigued through a maximal incremental cycle ergometry protocol. Meanwhile, the electromyography values of the external intercostal muscles and diaphragm were recorded bilaterally, and fatigue duration was determined.

Results: The root mean square of concave external intercostal muscles and concave diaphragm in patients with idiopathic scoliosis was significantly reduced during the fatiguing exercise protocol compared with healthy individuals. The median frequencies of the two sides differed significantly and were lower in patients with moderate scoliosis than healthy subjects. Fatigue duration (minutes) also was lower in patients with moderate scoliosis than healthy subjects.

Conclusions: Scoliosis causes respiratory muscle weakness and reduced fatigue duration in response to mild physical activity compared with healthy subjects and these dysfunctions appear to be related to the severity of scoliosis curvature (moderate > mild).
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.3109/09593985.2014.938382DOI Listing
November 2014

High purity heroin use among women in karaj, iran: a pilot study.

Iran J Psychiatry Behav Sci 2013 ;7(2):51-6

Clinical Psychologist, Psychological Services Centre, Islamic Azad University, Karaj Branch, Karaj, Iran.

Objective: High purity heroin use is a new epidemic health concern among Iranian drug-using women in recent years. However, the nature and initial factors associated with this serious health problem have not been studied yet.

Methods: To understand this issue, a cross-sectional study was conducted and sixty treatment and non-treatment seekers who met the Diagnostic and Statistical Manual of Mental Disorders, 4(th) ed., Text Revision (DSM.IV-TR) criteria for drug dependence with mean age of 28.7 (± 8.3) years were recruited from 16 addiction clinics and drop-in centers (DICs) in Karaj, Iran. First, demographics, and details of drug use and risky behaviors were collected based on items elicited from Addiction Severity Index (ASI). Then, initial factors associated with high purity heroin use were collected by interviewing and applying a researcher-made questionnaire. Data was statistically analyzed by descriptive methods of statistics, chi-square, and Student's independent t-test in SPSS software.

Results: Initiation of high purity heroin use was facilitated by family/relatives factor (66.7%), curiosity (60.1%), peers (54%), desire to experience rapid physical effects of high purity heroin compared with other opioids (50.1%), and treatment of general medical problems such as colic pain (33%). Chi-square test showed that non-treatment seekers were younger (less than 35 years) (66.6% vs. 56%, p ≤ 0.001) and mostly living with drug-dependent friends (26% vs. 3.3%, p ≤ 0.001) compared with treatment seekers. No relation was found among other factors.

Conclusions: Factors facilitating the initiation of high purity heroin use revealed in this study have not been fully addressed by current drug treatment services in Iran. To design comprehensive treatment programs, further studies on larger samples with more women are necessary.

Declaration Of Interest: None.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940000PMC
March 2014

Strength of hip muscle groups in sedentary women with patellofemoral pain syndrome.

J Back Musculoskelet Rehabil 2014 ;27(3):299-306

Department of Physiotherapy, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.

Objective: To compare the strength of hip muscle groups in sedentary women with bilateral patellofemoral pain syndrome (PFPS) with a matched control group of sedentary women without PFPS.

Methods: Twenty four women between 19 and 23 years of age (PFPS group, n=12; control group, n=12) participated in this study. Strength for all 6 hip muscle groups was measured bilaterally in all subjects using a stabilized Hand-held dynamometer.

Results: The hip musculature of sedentary women with bilateral PFPS was statistically weaker (range 31%-52%; p< 0.001) than that of the control group for all muscle groups.

Conclusion: This study demonstrated a statistically significant weakness of hip muscle groups in sedentary women with PFPS.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.3233/BMR-130447DOI Listing
April 2015