Publications by authors named "Z Gao"

8,717 Publications

Effects of polystyrene and triphenyl phosphate on growth, photosynthesis and oxidative stress of Chaetoceros meülleri.

Sci Total Environ 2021 Jul 21;797:149180. Epub 2021 Jul 21.

Institute of Marine Science and Technology, Shandong University, Qingdao 266237, PR China. Electronic address:

The toxicity of microplastics to marine organisms has attracted much attention; however, studies of their effects on marine microalgae remain limited. Here, the effects of the single and combined toxicity of polystyrene (PS) and triphenyl phosphate (TPhP) on the cell growth, photosynthesis, and oxidative stress of Chaetoceros meülleri were investigated. PS inhibited growth of the algae cells and caused a dose-dependent effect on oxidative stress. The significantly high production of reactive oxygen species (ROS) induced severe cell membrane damage, as confirmed by high fluorescence polarization. However, there was no obvious decrease in chlorophyll a content, and 80 mg/L of PS significantly promoted chlorophyll a synthesis. The TPhP also inhibited cell growth, except at low concentrations (0.2-0.8 mg/L), which stimulated algae growth over 48 h. Moreover, no obvious decrease in chlorophyll a and maximal photochemical efficiency of PSII was found in the TPhP experimental groups except for 3.2 mg/L TPhP, where the rapid light curves showed a significantly reduced photosynthetic capacity of algae. In addition, TPhP caused high ROS levels at 96 h, resulting in cell membrane damage. Using the additive index and independent action methods, the combined toxic effects of PS and TPhP on the algae were evaluated as antagonistic; however, cell membrane damage caused by high ROS levels was still noticeable. This study has shown the potential toxicity of PS and TPhP to marine microalgae, and provided insights into the combined risk assessment of TPhP and microplastics in the marine environment.
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http://dx.doi.org/10.1016/j.scitotenv.2021.149180DOI Listing
July 2021

HPM-16, a New Stable Interrupted Zeolite with a Multidimensional Mixed Medium-Large Pore System Containing Supercages.

Angew Chem Int Ed Engl 2021 Jul 26. Epub 2021 Jul 26.

Spanish Council for Scientific Research, Institute of Materials Science of Madrid, Sor Juana Inés de la Cruz, 3, 28049, Madrid, SPAIN.

HPM-16 is a highly porous germanosilicate zeolite with an interrupted framework that contains a three-dimensional system of 12+10×10(12)×12+10 membered ring (MR) pores. The 10(12) MR pore in the b direction is a 10MR pore with long 12MR stretches forming 30 Å  long tubular supercages. Along one direction the 10MR pores are fused, meaning that the  separation between adjacent pores consists of a single tetrahedron that is, additionally,   connected to only three additional tetrahedra (a Q 3 ). These fused pores are thus decorated  by T-OH groups along the whole diffusion path, creating a hydrophilic region embedded in an  otherwise essentially hydrophobic environment. The structure is built from highly porous  12×12×12 MR uninterrupted layers that are connected to each other through Q 3 producing a  second system of 10×10×10 MR pores. This zeolite can be extensively degermanated  yielding a material with high thermal stability, despite its interrupted nature.
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http://dx.doi.org/10.1002/anie.202106734DOI Listing
July 2021

Combined foliar and soil selenium fertilizer improves selenium transport and the diversity of rhizosphere bacterial community in oats.

Environ Sci Pollut Res Int 2021 Jul 26. Epub 2021 Jul 26.

Shanxi Institute of Geological Survey, Taiyuan, 030000, China.

Agronomic selenium (Se) biofortification of grain crops is considered the best method for increasing human Se intake, which may help people alleviate Se-deficiency. To investigate the efficiency of agronomic Se biofortification of oat, four Se fertilizer application treatments were tested: topsoil (T), foliar (S), the combination of T and S (TS), and control without Se application (CK). Compared with CK, TS significantly increased the 1000-grain weight, grain yield, Se contents in all parts of oats, contents of soil available N, K, and organic matter by 18%, 8.70%, 19.7-60.2%, 6.00%, 8.02%, and 17.95%, respectively. Leaves, roots, and ears had the highest conversion rate of exogenous Se in S (644.63%), T (416.00%), and TS (273.20%), respectively. TS also increased the activities of soil urease, alkaline phosphatase, and sucrose and the diversity of soil bacterial communities. TS and T increased the relative abundance of bacteria involved in the decomposition of organic matter, such as Actinobacteria, Gemmatimonadetes, Chloroflexi, and Bacteroidetes positively correlated with soil nutrients and enzyme activities, and reduced Proteobacteria and Firmicutes negatively correlated with them, Granulicella, Bacillus, Raoultella, Lactococcus, Klebsiella, and Pseudomonas. Furthermore, TS significantly increased the relative abundance of Planctomycetes, Chlorobi, Nitrospinae, Nitrospirae, Aciditeromonas, Gemmatimonas, Geobacter, and Thiobacter. T significantly increased the abundance of Lysobacter, Holophaga, Candidatus-Koribacter, Povalibacter, and Pyrinomonas. S did not significantly change the bacterial communities. Thus, a combined foliar and soil Se fertilizer proved conducive for achieving higher yield, grain Se content, and improving Se transport, the diversity of rhizosphere bacterial community, and bacterial functions in oats.
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http://dx.doi.org/10.1007/s11356-021-15439-4DOI Listing
July 2021

Rapid diagnosis of disseminated infection in formalin-fixed, paraffin-embedded specimen using next-generation sequencing: A case report.

World J Clin Cases 2021 Jul;9(20):5621-5630

State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, Guangdong Province, China.

Background: () belongs to the group of rapidly growing . This microorganism is associated with a wide spectrum of infectious diseases. Due to a low detection rate or the time required for conventional culture methodology, a rapid and broad-spectrum method is necessary to identify rare pathogens.

Case Summary: A 12-year-old immunocompetent girl presented with painful masses for five months. The first mass was found in the right upper quadrant of the abdomen, and was about 1 cm × 1.5 cm in size, tough but pliable in texture, with an irregular margin and tenderness. An abscess gradually formed and ulcerated with suppuration of the mass. Three new masses appeared on the back one by one. Chest computed tomography showed patchy and streaky cloudy opacities in both lungs. Needle aspiration of the abscess was performed, but the smear and conventional culture were negative, and the pathological examination showed no pathogens. We then performed next-generation sequencing using a formalin-fixed, paraffin-embedded specimen to identify the pathogen. A significantly high abundance of was detected. The patient's abscesses gradually decreased in size, while inflammation in both lungs improved following 12-wk of treatment. No recurrence was observed four months after the end of the one-year treatment period.

Conclusion: Next-generation sequencing is a promising tool for the rapid and accurate diagnosis of rare pathogens, even when using a formalin-fixed, paraffin-embedded specimen.
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http://dx.doi.org/10.12998/wjcc.v9.i20.5621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281395PMC
July 2021

Effects of mindfulness decompression therapy combined with transcranial magnetic stimulation in generalized anxiety disorder.

Am J Transl Res 2021 15;13(6):6827-6836. Epub 2021 Jun 15.

Department of Clinical Psychology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine Hangzhou, Zhejiang Province, China.

Objective: To explore the clinical effects of mindfulness decompression therapy combined with transcranial magnetic stimulation in generalized anxiety disorder.

Methods: In the present prospective study, ninety-two patients with generalized anxiety disorder were randomly divided into two groups, with 46 cases in each group. On the basis of drug treatment, patients in the control group received transcranial magnetic stimulation, and patients in the research group were treated with mindfulness decompression therapy combined with transcranial magnetic stimulation. The total effective rate, anxiety degree (evaluated by the Hamilton Anxiety Scale (HAMA) score), severity of condition (evaluated by the clinical global impression (CGI) score), comfort degree score (Psychology, physiology, environment, social culture), neuroelectrophysiological parameters and sleep quality (Pittsburgh sleep quality index (PSQI) factors) before and after treatment were compared between the two groups.

Results: After treatment, the research group had higher total effective rate than that of the control group (P<0.05); the HAMA score and CGI score of two groups were both decreased, and the research group decreased much more than the control group (P<0.05); mismatch negativity (MMN) latency, target N2 latency and target P3 latency of two groups were all decreased, MMN amplitude and none-target P2 amplitude were both increased, and the research group improved much more than the control group (P<0.05); the scores of social comfort, environmental comfort, physiological comfort and psychological comfort of two groups were all increased, and the corresponding scores of the research group were all higher than those of the control group (P<0.05); PSQI scores of two groups were all decreased, and the research group had lower PSQI scores than the control group (P<0.05).

Conclusion: Mindfulness decompression therapy combined with transcranial magnetic stimulation effectively relieve anxiety symptoms and improve comfort degree and sleep quality in patients with generalized anxiety disorder.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290819PMC
June 2021
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