Publications by authors named "Yvonne Genzel"

65Publications

High cell density perfusion process for high yield of influenza A virus production using MDCK suspension cells.

Appl Microbiol Biotechnol 2021 Feb 30;105(4):1421-1434. Epub 2021 Jan 30.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.

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February 2021

Production of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparison of Platform Technologies for Viral Vector Production.

Biotechnol J 2021 Jan 8;16(1):e2000024. Epub 2020 Sep 8.

Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Sandtorstr. 1, Magdeburg, 39106, Germany.

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January 2021

Application of an Inclined Settler for Cell Culture-Based Influenza A Virus Production in Perfusion Mode.

Front Bioeng Biotechnol 2020 2;8:672. Epub 2020 Jul 2.

Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.

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July 2020

Virus harvesting in perfusion culture: Choosing the right type of hollow fiber membrane.

Biotechnol Bioeng 2020 10 2;117(10):3040-3052. Epub 2020 Jul 2.

Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.

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October 2020

Performance of an acoustic settler versus a hollow fiber-based ATF technology for influenza virus production in perfusion.

Appl Microbiol Biotechnol 2020 Jun 15;104(11):4877-4888. Epub 2020 Apr 15.

Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstr. 1, 39106, Magdeburg, Germany.

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June 2020

A dynamic model linking cell growth to intracellular metabolism and extracellular by-product accumulation.

Biotechnol Bioeng 2020 05 15;117(5):1533-1553. Epub 2020 Feb 15.

Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.

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May 2020

Perfusion Control for High Cell Density Cultivation and Viral Vaccine Production.

Methods Mol Biol 2020 ;2095:141-168

Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.

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February 2021

Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the "von Magnus effect".

PLoS One 2019 5;14(11):e0224317. Epub 2019 Nov 5.

Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.

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April 2020

Influenza A virus production in a single-use orbital shaken bioreactor with ATF or TFF perfusion systems.

Vaccine 2019 11 29;37(47):7011-7018. Epub 2019 Jun 29.

Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstr. 1, 39106 Magdeburg, Germany.

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November 2019

Semi-perfusion cultures of suspension MDCK cells enable high cell concentrations and efficient influenza A virus production.

Vaccine 2019 11 29;37(47):7003-7010. Epub 2019 Apr 29.

Bioprocess Engineering Group, Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, 39106 Magdeburg, Germany; Chair of Bioprocess Engineering, Otto-von-Guericke University Magdeburg, Universitaetsplatz 2, 39106 Magdeburg, Germany.

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November 2019

Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1.

Vaccine 2019 11 17;37(47):7019-7028. Epub 2019 Apr 17.

Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Sandtorstr. 1, 39106 Magdeburg, Germany; Chair for Bioprocess Engineering, Otto-von-Guericke-University Magdeburg, Universitätsplatz 2, 39106 Magdeburg, Germany.

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November 2019

High titer MVA and influenza A virus production using a hybrid fed-batch/perfusion strategy with an ATF system.

Appl Microbiol Biotechnol 2019 Apr 23;103(7):3025-3035. Epub 2019 Feb 23.

Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstr. 1, 39106, Magdeburg, Germany.

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April 2019

Process intensification of EB66® cell cultivations leads to high-yield yellow fever and Zika virus production.

Appl Microbiol Biotechnol 2018 Oct 8;102(20):8725-8737. Epub 2018 Aug 8.

Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Magdeburg, Sandtorstr. 1, 39106, Magdeburg, Germany.

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October 2018

High-cell-density cultivations to increase MVA virus production.

Vaccine 2018 05 9;36(22):3124-3133. Epub 2018 Feb 9.

Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstr. 1, 39106 Magdeburg, Germany; Chair for Bioprocess Engineering, Otto-von-Guericke-University Magdeburg, Universitätsplatz 2, 39106 Magdeburg, Germany.

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May 2018