Publications by authors named "Yvonne Genzel"

65Publications

Tracking changes in adaptation to suspension growth for MDCK cells: cell growth correlates with levels of metabolites, enzymes and proteins.

Authors:
Sabine Pech Markus Rehberg Robert Janke Dirk Benndorf Yvonne Genzel Thilo Muth Albert Sickmann Erdmann Rapp Udo Reichl

Appl Microbiol Biotechnol 2021 Feb 13. Epub 2021 Feb 13.

Bioprocess Engineering, Otto von Guericke University Magdeburg, Magdeburg, Germany.

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February 2021

High cell density perfusion process for high yield of influenza A virus production using MDCK suspension cells.

Authors:
Yixiao Wu Thomas Bissinger Yvonne Genzel Xuping Liu Udo Reichl Wen-Song Tan

Appl Microbiol Biotechnol 2021 Feb 30;105(4):1421-1434. Epub 2021 Jan 30.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.

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February 2021

OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential.

Authors:
Marc D Hein Heike Kollmus Pavel Marichal-Gallardo Sebastian Püttker Dirk Benndorf Yvonne Genzel Klaus Schughart Sascha Y Kupke Udo Reichl

Appl Microbiol Biotechnol 2021 Jan 4;105(1):129-146. Epub 2020 Dec 4.

Bioprocess Engineering, Otto von Guericke University Magdeburg, Magdeburg, Germany.

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January 2021

Cell Bank Origin of MDCK Parental Cells Shapes Adaptation to Serum-Free Suspension Culture and Canine Adenoviral Vector Production.

Authors:
Ana Filipa Rodrigues Paulo Fernandes Tanja Laske Rute Castro Paula Marques Alves Yvonne Genzel Ana Sofia Coroadinha

Int J Mol Sci 2020 Aug 25;21(17). Epub 2020 Aug 25.

iBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2781-901 Oeiras, Portugal.

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August 2020

Production of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparison of Platform Technologies for Viral Vector Production.

Authors:
Gwendal Gränicher Felipe Tapia Ilona Behrendt Ingo Jordan Yvonne Genzel Udo Reichl

Biotechnol J 2021 Jan 8;16(1):e2000024. Epub 2020 Sep 8.

Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Sandtorstr. 1, Magdeburg, 39106, Germany.

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January 2021

Application of an Inclined Settler for Cell Culture-Based Influenza A Virus Production in Perfusion Mode.

Authors:
Juliana Coronel Gwendal Gränicher Volker Sandig Thomas Noll Yvonne Genzel Udo Reichl

Front Bioeng Biotechnol 2020 2;8:672. Epub 2020 Jul 2.

Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.

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July 2020

Virus harvesting in perfusion culture: Choosing the right type of hollow fiber membrane.

Authors:
Alexander Nikolay Joris de Grooth Yvonne Genzel Jeffery A Wood Udo Reichl

Biotechnol Bioeng 2020 10 2;117(10):3040-3052. Epub 2020 Jul 2.

Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.

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October 2020

Performance of an acoustic settler versus a hollow fiber-based ATF technology for influenza virus production in perfusion.

Authors:
Gwendal Gränicher Juliana Coronel Felix Trampler Ingo Jordan Yvonne Genzel Udo Reichl

Appl Microbiol Biotechnol 2020 Jun 15;104(11):4877-4888. Epub 2020 Apr 15.

Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstr. 1, 39106, Magdeburg, Germany.

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June 2020

A dynamic model linking cell growth to intracellular metabolism and extracellular by-product accumulation.

Authors:
João R C Ramos Alexander G Rath Yvonne Genzel Volker Sandig Udo Reichl

Biotechnol Bioeng 2020 05 15;117(5):1533-1553. Epub 2020 Feb 15.

Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.

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May 2020

Perfusion Control for High Cell Density Cultivation and Viral Vaccine Production.

Authors:
Alexander Nikolay Thomas Bissinger Gwendal Gränicher Yixiao Wu Yvonne Genzel Udo Reichl

Methods Mol Biol 2020 ;2095:141-168

Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.

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February 2021

Orbitally Shaken Single-Use Bioreactor for Animal Cell Cultivation: Fed-Batch and Perfusion Mode.

Authors:
Tim Bürgin Juliana Coronel Gerrit Hagens Michael V Keebler Yvonne Genzel Udo Reichl Tibor Anderlei

Methods Mol Biol 2020 ;2095:105-123

Adolf Kühner AG, Birsfelden, Switzerland.

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February 2021

Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the "von Magnus effect".

Authors:
Felipe Tapia Daniel Wohlfarth Volker Sandig Ingo Jordan Yvonne Genzel Udo Reichl

PLoS One 2019 5;14(11):e0224317. Epub 2019 Nov 5.

Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.

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April 2020

Production of Defective Interfering Particles of Influenza A Virus in Parallel Continuous Cultures at Two Residence Times-Insights From qPCR Measurements and Viral Dynamics Modeling.

Authors:
Felipe Tapia Tanja Laske Milena A Wasik Markus Rammhold Yvonne Genzel Udo Reichl

Front Bioeng Biotechnol 2019 18;7:275. Epub 2019 Oct 18.

Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.

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October 2019

Influenza A virus production in a single-use orbital shaken bioreactor with ATF or TFF perfusion systems.

Authors:
Juliana Coronel Ilona Behrendt Tim Bürgin Tibor Anderlei Volker Sandig Udo Reichl Yvonne Genzel

Vaccine 2019 11 29;37(47):7011-7018. Epub 2019 Jun 29.

Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstr. 1, 39106 Magdeburg, Germany.

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November 2019

Semi-perfusion cultures of suspension MDCK cells enable high cell concentrations and efficient influenza A virus production.

Authors:
Thomas Bissinger Johannes Fritsch Adrian Mihut Yixiao Wu Xuping Liu Yvonne Genzel Wen-Song Tan Udo Reichl

Vaccine 2019 11 29;37(47):7003-7010. Epub 2019 Apr 29.

Bioprocess Engineering Group, Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, 39106 Magdeburg, Germany; Chair of Bioprocess Engineering, Otto-von-Guericke University Magdeburg, Universitaetsplatz 2, 39106 Magdeburg, Germany.

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November 2019

Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1.

Authors:
Gwendal Gränicher Juliana Coronel Alexander Pralow Pavel Marichal-Gallardo Michael Wolff Erdmann Rapp Alexander Karlas Volker Sandig Yvonne Genzel Udo Reichl

Vaccine 2019 11 17;37(47):7019-7028. Epub 2019 Apr 17.

Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Sandtorstr. 1, 39106 Magdeburg, Germany; Chair for Bioprocess Engineering, Otto-von-Guericke-University Magdeburg, Universitätsplatz 2, 39106 Magdeburg, Germany.

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November 2019

High titer MVA and influenza A virus production using a hybrid fed-batch/perfusion strategy with an ATF system.

Authors:
Daniel Vázquez-Ramírez Ingo Jordan Volker Sandig Yvonne Genzel Udo Reichl

Appl Microbiol Biotechnol 2019 Apr 23;103(7):3025-3035. Epub 2019 Feb 23.

Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstr. 1, 39106, Magdeburg, Germany.

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April 2019

Process intensification of EB66® cell cultivations leads to high-yield yellow fever and Zika virus production.

Authors:
Alexander Nikolay Arnaud Léon Klaus Schwamborn Yvonne Genzel Udo Reichl

Appl Microbiol Biotechnol 2018 Oct 8;102(20):8725-8737. Epub 2018 Aug 8.

Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Magdeburg, Sandtorstr. 1, 39106, Magdeburg, Germany.

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October 2018

Vaccine Technology VI: Innovative and integrated approaches in vaccine development.

Authors:
Laura A Palomares Tarit K Mukhopadhyay Yvonne Genzel Linda H L Lua Manon M J Cox

Vaccine 2018 05 11;36(22):3061-3063. Epub 2018 Apr 11.

NextWaveBio, CT, USA. Electronic address:

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May 2018

High-cell-density cultivations to increase MVA virus production.

Authors:
Daniel Vázquez-Ramírez Yvonne Genzel Ingo Jordan Volker Sandig Udo Reichl

Vaccine 2018 05 9;36(22):3124-3133. Epub 2018 Feb 9.

Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstr. 1, 39106 Magdeburg, Germany; Chair for Bioprocess Engineering, Otto-von-Guericke-University Magdeburg, Universitätsplatz 2, 39106 Magdeburg, Germany.

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May 2018