Dr. Yuying Liu, PhD, MEd - The University of Texas Health Science Center at Houston McGovern Medical School - Associate Professor

Dr. Yuying Liu

PhD, MEd

The University of Texas Health Science Center at Houston McGovern Medical School

Associate Professor

Houston, Texas

ORCID logohttps://orcid.org/0000-0003-3848-9254

Dr. Yuying Liu, PhD, MEd - The University of Texas Health Science Center at Houston McGovern Medical School - Associate Professor

Dr. Yuying Liu

PhD, MEd

Introduction

Primary Affiliation: The University of Texas Health Science Center at Houston McGovern Medical School - Houston, Texas

Research Interests:

Experience

Mar 2011 - Aug 2016
The University of Texas Health Science Center at Houston McGovern Medical School
Assistant Professor
Pediatrics
Apr 2009 - Mar 2011
The University of Texas Health Science Center at Houston McGoven Medical School
Instructor
Pediatrics
Nov 2007 - Mar 2009
The University of Texas Health Science Center at Houston McGovern Medical School
Research Scientist
Pediatrics
Mar 2004 - Sep 2006
The University of Texas M.D. Anderson Cancer Center
Instructor
Experimental Therapeutics

Publications

40Publications

586Reads

59Profile Views

336PubMed Central Citations

DSM 17938 feeding of healthy newborn mice regulates immune responses while modulating gut microbiota and boosting beneficial metabolites.

Am J Physiol Gastrointest Liver Physiol 2019 Sep 4. Epub 2019 Sep 4.

Pediatrics-Gastroenterocology, University of Texas Health Science Center at Houston Medical School, United States.

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http://dx.doi.org/10.1152/ajpgi.00107.2019DOI Listing
September 2019
3.798 Impact Factor

Human Breast Milk Promotes the Secretion of Potentially Beneficial Metabolites by Probiotic DSM 17938.

Nutrients 2019 Jul 9;11(7). Epub 2019 Jul 9.

Department of Pediatrics, Division of Gastroenterology, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030, USA.

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http://dx.doi.org/10.3390/nu11071548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683045PMC
July 2019
2 Reads
3.148 Impact Factor

Human breast milk promotes the immunomodulatory function of probiotic Lactobacillus reuteri DSM 17938 in the neonatal rat intestine

J Prob Health 2019 Jul 26; 7:210

Journal of Probiotics & Health

Abstract

Background and Objective: Breast milk has many growth-promoting and immune-active components, including transforming growth factor-β, lactoferrin, lysozyme, immunoglobulin A, and prebiotics such as the human milk oligosaccharides. Treatment with Lactobacillus reuteri DSM 17938 (LR), a probiotic with immunomodulatory functions, significantly increases regulatory T cells (Tregs) in the intestinal mucosa of newborn suckling rats. In humans, treatment with LR of infants with colic reduces crying optimally if the infants are breast-fed. Therefore, we examined the effects of human breast milk (HBM) on LR-associated immune modulation.

Methods: Newborn rats were divided into 8 feeding groups, including dam-fed ± LR (106 CFU/kg bw/day, daily), formula-fed ± LR, formula with 20 % (v/v) HBM-fed ± LR, and HBM-fed ± LR. Pups were fed by gavage from d1 to d3 of age. Subsequently, we measured intestinal immune cell profiles, including Tregs and tolerogenic dendritic cells (tDCs) by flow cytometry. We also measured inflammatory cytokine and chemokine levels of interleukin (IL)-1β and cytokine-induced neutrophil chemoattratant (CINC)-1 in intestinal tissue lysates by ELISA.

Results and Conclusion: (1) Formula feeding increased intestinal CD3+ T cells, CD4+ helper T (TH) cells and CD11c+ DCs, pro-inflammatory effects which were reversed by HBM. (2) When comparing HBM-fed with formula-fed newborns, HBM supplementation produced a lower percentage of CD4+ TH cells and a higher percentage of CD8+ (cytotoxic) T cells, while reducing protein levels of IL-1β and CINC-1 in the intestine. (3) Probiotic LR feeding maximally stimulated the percentage of intestinal Tregs and tDCs when the pups were fed HBM. In conclusion, HBM reduced formula-induced intestinal gut immune activation, and the addition of LR further promoted immune tolerance.

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July 2019
1 Read

Reduces the Severity of Experimental Autoimmune Encephalomyelitis in Mice by Modulating Gut Microbiota.

Front Immunol 2019 7;10:385. Epub 2019 Mar 7.

Division of Gastroenterology, Departments of Pediatrics, The University of Texas Health Science Center at Houston-McGovern Medical School, Houston, TX, United States.

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00385
Publisher Site
http://dx.doi.org/10.3389/fimmu.2019.00385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416370PMC
March 2019
22 Reads

Plasma Urea Cycle Metabolites May Be Useful Biomarkers in Children With Eosinophilic Esophagitis.

Front Pediatr 2018 10;6:423. Epub 2019 Jan 10.

Department of Pediatric Gastroenterology, University of Texas McGovern Medical School, Houston, TX, United States.

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http://dx.doi.org/10.3389/fped.2018.00423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335364PMC
January 2019
3 Reads

Infant Colic Represents Gut Inflammation and Dysbiosis.

J Pediatr 2018 12 31;203:55-61.e3. Epub 2018 Aug 31.

Department of Pediatrics, Gastroenterology Division, McGovern Medical School, UTHealth, Houston, TX.

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http://dx.doi.org/10.1016/j.jpeds.2018.07.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669027PMC
December 2018
9 Reads
1 Citation
3.790 Impact Factor

Infantile Colic: New Insights into an Old Problem.

Gastroenterol Clin North Am 2018 12 28;47(4):829-844. Epub 2018 Sep 28.

Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, The University of Texas Health Science Center at Houston McGovern Medical School, 6431 Fannin Street, MSB 3.137, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.gtc.2018.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659398PMC
December 2018
5 Reads
2.824 Impact Factor

Probiotics in Disease Prevention and Treatment.

J Clin Pharmacol 2018 Oct;58 Suppl 10:S164-S179

Department of Pediatrics, Division of Gastroenterology, and the Pediatric Research Center, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX, USA.

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http://dx.doi.org/10.1002/jcph.1121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656559PMC
October 2018
4 Reads

Probiotics in Autoimmune and Inflammatory Disorders.

Nutrients 2018 Oct 18;10(10). Epub 2018 Oct 18.

The Department of Pediatrics, Division of Gastroenterology, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030, USA.

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http://dx.doi.org/10.3390/nu10101537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213508PMC
October 2018
3 Reads
3.150 Impact Factor

Protective effect of Lactobacillus reuteri DSM 17938 against experimental necrotizing enterocolitis is mediated by Toll-like receptor 2.

Am J Physiol Gastrointest Liver Physiol 2018 08 12;315(2):G231-G240. Epub 2018 Apr 12.

Division of Gastroenterology, Department of Pediatrics, The University of Texas Health Science Center at Houston McGovern Medical School , Houston, Texas.

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http://dx.doi.org/10.1152/ajpgi.00084.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139641PMC
August 2018
11 Reads
1 Citation
3.800 Impact Factor

Adenosine A Receptor Deletion Blocks the Beneficial Effects of in Regulatory T-Deficient Scurfy Mice.

Front Immunol 2017 6;8:1680. Epub 2017 Dec 6.

Division of Gastroenterology, Department of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States.

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http://dx.doi.org/10.3389/fimmu.2017.01680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723640PMC
December 2017
7 Reads
1 Citation

Lactobacillus reuteri for Infants with Colic: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial.

J Pediatr 2017 12 29;191:170-178.e2. Epub 2017 Sep 29.

Department of Pediatrics, the University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2017.07.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336100PMC
December 2017
61 Reads
3 Citations
3.790 Impact Factor

Resetting microbiota by Lactobacillus reuteri inhibits T reg deficiency-induced autoimmunity via adenosine A2A receptors.

J Exp Med 2017 01 19;214(1):107-123. Epub 2016 Dec 19.

Pediatrics Gastroenterology, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030

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http://dx.doi.org/10.1084/jem.20160961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206500PMC
January 2017
43 Reads
9 Citations
12.520 Impact Factor

Can probiotics benefit children with autism spectrum disorders?

World J Gastroenterol 2016 Dec;22(46):10093-10102

Fernando Navarro, Yuying Liu, Jon Marc Rhoads, Department of Pediatrics, Division of Gastroenterology, the University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030, United States.

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http://dx.doi.org/10.3748/wjg.v22.i46.10093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155168PMC
December 2016
9 Reads
7 Citations
2.370 Impact Factor

"LOCK"ing up allergic responses with a Polish probiotic.

Cell Mol Immunol 2016 Mar 23;13(2):263-4. Epub 2015 Mar 23.

Department of Pediatrics, Division of Gastroenterology, The University of Texas Health Science Center at Houston Medical School, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/cmi.2015.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786631PMC
March 2016
3 Reads
4.112 Impact Factor

Circulating L-selectin expressing-T cell subsets correlate with the severity of Foxp3 deficiency autoimmune disease

Int J Clin Exp Pathol 2016;9(2):899-909

International Journal of Clinical and Experimental Pathology

L-selectin (CD62L) is normally highly expressed in naïve T cells. The expression levels of CD62L have been reported to be decreased on T cells during the inflammatory state. It is currently unknown whether the frequency of CD62L+ T cell subsets in the peripheral blood can be used as a marker to indicate is disease severity during inflammation. Our study evaluated whether circulating CD62L+ T cell subsets correlate with the severity of disease by testing an autoimmune condition of scurfy (sf) mouse associated with multi-organ inflammation due to regulatory T cell deficiency. We observed that scurfy mice spontaneously developed an inflammatory phenotype with a significant decrease in the percentage of CD62L-expressing CD4+ T and CD8+ T cells in the peripheral blood. The percentage of CD62L+CD4+ T and CD62L+CD8+ T cells negatively correlated with disease severity, as determined by the weight of spleen and liver, as well as the mean area of lymphocyte infiltrates in lung and liver. The percentage of CD8+ T cells also correlated directly with these markers of disease severity. To conclude, our results support the concept that circulating CD62L-expressing T cells may be used as markers of disease severity in sf mice which is equivalent to a syndrome characterized by immune dysregulation with polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX syndrome) in humans, or in other autoimmune or inflammatory conditions.

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March 2016
6 Reads

Hypoallergenic formula with Lactobacillus rhamnosus GG for babies with colic: A pilot study of recruitment, retention, and fecal biomarkers.

World J Gastrointest Pathophysiol 2016 Feb;7(1):160-70

Nicole Y Fatheree, Yuying Liu, Melissa Van Arsdall, Juleen Min, Dat Q Tran, Fernando Navarro, Wallace Gleason, Sara Gonzalez, J Marc Rhoads, Department of Pediatrics, the University of Texas Health Science Center at Houston Medical School, Houston, TX 77030, United States.

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http://dx.doi.org/10.4291/wjgp.v7.i1.160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753182PMC
February 2016
45 Reads
3 Citations

Oral administration of surfactant protein-a reduces pathology in an experimental model of necrotizing enterocolitis.

J Pediatr Gastroenterol Nutr 2015 May;60(5):613-20

*Department of Pediatrics, Division of Neonatal-Perinatal Medicine †Department of Pediatrics, Division of Pediatric Gastroenterology ‡Department of Pediatrics, Pediatric Research Center, University of Texas Health Science Center at Houston, Houston §Department of Pediatrics, Center for Host Defense, Inflammation and Lung Disease, Pennsylvania State University College of Medicine, Hershey ¶Division of Pulmonary, Critical Care Medicine and Sleep, University of Cincinnati School of Medicine, Cincinnati, OH.

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http://dx.doi.org/10.1097/MPG.0000000000000678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027895PMC
May 2015
20 Reads
5 Citations
2.625 Impact Factor

FoxP3⁺ regulatory T cells attenuate experimental necrotizing enterocolitis.

PLoS One 2013 18;8(12):e82963. Epub 2013 Dec 18.

Department of Pediatrics, The University of Texas Medical School, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082963PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867412PMC
October 2014
16 Reads
10 Citations
3.234 Impact Factor

Lactobacillus reuteri DSM 17938 differentially modulates effector memory T cells and Foxp3+ regulatory T cells in a mouse model of necrotizing enterocolitis.

Am J Physiol Gastrointest Liver Physiol 2014 Jul 22;307(2):G177-86. Epub 2014 May 22.

Division of Gastroenterology, Department of Pediatrics, University of Texas Health Science Center at Houston Medical School, Houston, Texas; Pediatric Research Center, University of Texas Health Science Center at Houston Medical School, Houston, Texas

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http://dx.doi.org/10.1152/ajpgi.00038.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101683PMC
July 2014
11 Reads
13 Citations
3.800 Impact Factor

Communication between B-Cells and Microbiota for the Maintenance of Intestinal Homeostasis

Antibodies 2013, 2(4), 535-55

Antibodies

The human intestine is populated with an extremely dense and diverse bacterial community. Commensal bacteria act as an important antigenic stimulus producing the maturation of gut-associated lymphoid tissue (GALT). The production of immunoglobulin (Ig) A by B-cells in the GALT is one of the immune responses following intestinal colonization of bacteria. The switch of B-cells from IgM to IgA-producing cells in the Peyer’s patches and neighboring lamina propria proceeds by T-cell-dependent and T-cell-independent mechanisms. Several grams of secretory IgA (SIgA) are released into the intestine each day. SIgA serves as a first-line of defense in protecting the intestinal epithelium from enteric toxins and pathogenic microorganisms. SIgA has a capacity to directly quench bacterial virulence factors, influence the composition of the intestinal microbiota, and promote the transportation of antigens across the intestinal epithelium to GALT and down-regulate proinflammatory responses associated with the uptake of highly pathogenic bacteria and potentially allergenic antigens. This review summarizes the reciprocal interactions between intestinal B cells and bacteria, specifically, the formation of IgA in the gut, the role of intestinal IgA in the regulation of bacterial communities and the maintenance of intestinal homeostasis, and the effects of probiotics on IgA levels in the gastrointestinal tract.

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December 2013
23 Reads

Lactobacillus reuteri DSM 17938 changes the frequency of Foxp3+ regulatory T cells in the intestine and mesenteric lymph node in experimental necrotizing enterocolitis.

PLoS One 2013 20;8(2):e56547. Epub 2013 Feb 20.

Divisions of Gastroenterology and Allergy-Immunology, Department of Pediatrics, The University of Texas Health Science Center at Houston Medical School, Houston, Texas, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056547PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577854PMC
September 2013
22 Reads
18 Citations
3.234 Impact Factor

Arginine and citrulline protect intestinal cell monolayer tight junctions from hypoxia-induced injury in piglets.

Pediatr Res 2012 Dec 5;72(6):576-82. Epub 2012 Oct 5.

Department of Pediatrics, Division of Neonatology, University of Texas Health Science Center, Houston, Texas, USA.

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http://dx.doi.org/10.1038/pr.2012.137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976428PMC
December 2012
7 Reads
3 Citations
2.314 Impact Factor

Bax345/BLyS: a novel, completely human fusion protein targeting malignant B cells and delivering a unique mitochondrial toxin.

Cancer Lett 2012 Sep 1;322(2):159-68. Epub 2012 Mar 1.

Department of Experimental Therapeutics, The University of Texas M.D. Anderson Cancer Center, Houston, 77030, USA.

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http://dx.doi.org/10.1016/j.canlet.2012.02.029DOI Listing
September 2012
45 Reads
2 Citations
5.621 Impact Factor

Impaired gastric emptying and small bowel transit in children with mitochondrial disorders.

J Pediatr Gastroenterol Nutr 2012 Aug;55(2):194-9

Department of Pediatrics, University of Texas Health Science Center at Houston Medical School, Houston, TX 77030, USA.

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http://dx.doi.org/10.1097/MPG.0b013e3182514805DOI Listing
August 2012
5 Reads
6 Citations
2.625 Impact Factor

Lactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-κB signaling in the intestine.

Am J Physiol Gastrointest Liver Physiol 2012 Mar 29;302(6):G608-17. Epub 2011 Dec 29.

Department of Pediatrics, Division of Gastroenterology, University of Texas Health Science Center at Houston Medical School, USA.

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http://dx.doi.org/10.1152/ajpgi.00266.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311308PMC
March 2012
12 Reads
39 Citations
3.800 Impact Factor

Infant formula alters surfactant protein A (SP-A) and SP-B expression in pulmonary epithelial cells.

Pediatr Pulmonol 2011 Sep 25;46(9):903-12. Epub 2011 Apr 25.

Division of Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/ppul.21455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671285PMC
September 2011
8 Reads
2 Citations

Human-derived probiotic Lactobacillus reuteri strains differentially reduce intestinal inflammation.

Am J Physiol Gastrointest Liver Physiol 2010 Nov 26;299(5):G1087-96. Epub 2010 Aug 26.

Department of Pediatrics, Division of Gastroenterology and Pediatric Research Institute, The University of Texas Health Science Center at Houston, Houston, Texas 7703, USA.

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http://dx.doi.org/10.1152/ajpgi.00124.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993169PMC
November 2010
19 Reads
42 Citations
3.800 Impact Factor

Characterization and mechanistic studies of a novel melanoma-targeting construct containing IκBa for specific inhibition of nuclear factor-κB activity.

Neoplasia 2010 Oct;12(10):766-77

Immunopharmacology & Targeted Therapy Laboratory, Department of Experimental Therapeutics, MD Anderson Cancer Center, Houston, TX 77030,USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950326PMC
http://dx.doi.org/10.1593/neo.10214DOI Listing
October 2010
26 Reads
6 Citations

Altered fecal microflora and increased fecal calprotectin in infants with colic.

J Pediatr 2009 Dec 22;155(6):823-828.e1. Epub 2009 Jul 22.

Department of Pediatrics, University of Texas Health Sciences Center at Houston-School of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.jpeds.2009.05.012DOI Listing
December 2009
16 Reads
24 Citations
3.790 Impact Factor

Changes in intestinal Toll-like receptors and cytokines precede histological injury in a rat model of necrotizing enterocolitis.

Am J Physiol Gastrointest Liver Physiol 2009 Sep 16;297(3):G442-50. Epub 2009 Jul 16.

Department of Pediatrics, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1152/ajpgi.00182.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739826PMC
September 2009
17 Reads
39 Citations
3.800 Impact Factor

Arginine stimulates cdx2-transformed intestinal epithelial cell migration via a mechanism requiring both nitric oxide and phosphorylation of p70 S6 kinase.

J Nutr 2008 Sep;138(9):1652-7

Department of Pediatrics, University of Texas Health Science Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/jn/138.9.1652DOI Listing
September 2008
5 Reads
12 Citations
3.880 Impact Factor

The antimelanoma immunocytokine scFvMEL/TNF shows reduced toxicity and potent antitumor activity against human tumor xenografts.

Neoplasia 2006 May;8(5):384-93

Immunopharmacology and Targeted Therapy Laboratory, Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1593/neo.06121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592449PMC
May 2006
11 Reads
12 Citations

Targeted apoptosis activation with GrB/scFvMEL modulates melanoma growth, metastatic spread, chemosensitivity, and radiosensitivity.

Neoplasia 2006 Feb;8(2):125-35

Immunopharmacology and Targeted Therapy Section, Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1593/neo.05556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1578517PMC
February 2006
13 Reads
12 Citations

Recombinant single-chain antibody fusion construct targeting human melanoma cells and containing tumor necrosis factor.

Int J Cancer 2004 Feb;108(4):549-57

Immunopharmacology and Targeted Therapy Section, Department of Bioimmunotherapy, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1002/ijc.11524DOI Listing
February 2004
5 Reads
6 Citations
5.085 Impact Factor

Targeted delivery of human pro-apoptotic enzymes to tumor cells: In vitro studies describing a novel class of recombinant highly cytotoxic agents.

Mol Cancer Ther 2003 Dec;2(12):1341-50

Immunopharmacology and Targeted Therapy Section, Department of Bioimmunotherapy, M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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December 2003
8 Reads
16 Citations
5.683 Impact Factor

Mechanistic studies of a novel human fusion toxin composed of vascular endothelial growth factor (VEGF)121 and the serine protease granzyme B: directed apoptotic events in vascular endothelial cells.

Mol Cancer Ther 2003 Oct;2(10):949-59

Immunopharmacology and Targeted Therapy Section, Department of Bioimmunotherapy, M. D. Anderson Cancer Center, University of Texas, Houston, TX 77030, USA.

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October 2003
34 Reads
5 Citations
5.683 Impact Factor

Design, expression, purification, and characterization, in vitro and in vivo, of an antimelanoma single-chain Fv antibody fused to the toxin gelonin.

Cancer Res 2003 Jul;63(14):3995-4002

Department of Bioimmunotherapy, Section of Immunopharmacology and Targeted Therapy, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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July 2003
11 Reads
26 Citations
9.330 Impact Factor

Top co-authors

Nicole Y Fatheree
Nicole Y Fatheree

the University of Texas Health Science Center at Houston McGovern Medical School

13
Dat Q Tran
Dat Q Tran

Laboratory of Immunology

13
Jon Marc Rhoads
Jon Marc Rhoads

McGovern Medical School

12
Lawrence H Cheung
Lawrence H Cheung

The University of Texas MD Anderson Cancer Center

8
Michael G Rosenblum
Michael G Rosenblum

University of Potsdam

8
Thomas K Hoang
Thomas K Hoang

McGovern Medical School

7
Baokun He
Baokun He

The University of Texas Health Science Center at Houston

5
Christopher M Taylor
Christopher M Taylor

Louisiana State University Health Sciences Center

5
Fernando Navarro
Fernando Navarro

University of South Carolina School of Medicine

4
Meng Luo
Meng Luo

Shanghai Ninth People's Hospital

4