Publications by authors named "Yuyang Jiang"

100Publications

NEAT1 regulates microtubule stabilization via FZD3/GSK3β/P-tau pathway in SH-SY5Y cells and APP/PS1 mice.

Aging (Albany NY) 2020 Nov 18;12. Epub 2020 Nov 18.

State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Shenzhen 518055, P.R. China.

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http://dx.doi.org/10.18632/aging.104098DOI Listing
November 2020

Streaming-enhanced, chip-based biosensor with acoustically active, biomarker-functionalized micropillars: A case study of thrombin detection.

Talanta 2021 Jan 13;222:121480. Epub 2020 Aug 13.

State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, Guangdong, 518055, China.

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http://dx.doi.org/10.1016/j.talanta.2020.121480DOI Listing
January 2021

Primary cutaneous CD4 small/medium pleomorphic T-cell lymphoproliferative disorder in a woman successfully treated with intralesional interleukin injection and occlusive corticosteroid.

Indian J Dermatol Venereol Leprol 2020 Nov-Dec;86(6):726-729

Department of Dermatology and Venereology, First Affiliated Hospital of Guangxi Medical University, Nanning, China.

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http://dx.doi.org/10.4103/ijdvl.IJDVL_814_19DOI Listing
October 2020

Zeptomolar-level one-pot simultaneous detection of multiple colorectal cancer microRNAs by cascade isothermal amplification.

Biosens Bioelectron 2020 Dec 17;169:112631. Epub 2020 Sep 17.

State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing, 100084, China. Electronic address:

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http://dx.doi.org/10.1016/j.bios.2020.112631DOI Listing
December 2020

Polydopamine-Modified TS-1 Zeolite Framework Nanoparticles as a Matrix for the Analysis of Small Molecules by MALDI-TOF MS.

ACS Omega 2020 Aug 3;5(32):19952-19959. Epub 2020 Aug 3.

State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.

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http://dx.doi.org/10.1021/acsomega.0c00992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439277PMC
August 2020

Highly Selective Oxidation of Organic Sulfides by a Conjugated Polymer as the Photosensitizer for Singlet Oxygen Generation.

ACS Appl Mater Interfaces 2020 Aug 22;12(31):35475-35481. Epub 2020 Jul 22.

Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China.

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http://dx.doi.org/10.1021/acsami.0c10162DOI Listing
August 2020

Discovery of triazolo [1,5-a] pyridine derivatives as novel JAK1/2 inhibitors.

Bioorg Med Chem Lett 2020 Jul 28;30(14):127225. Epub 2020 Apr 28.

Department of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, PR China; Joint Key State Laboratory of Tumor Chemogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, PR China; School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2020.127225DOI Listing
July 2020

Current discovery strategies for hepatocellular carcinoma therapeutics.

Expert Opin Drug Discov 2020 02 6;15(2):243-258. Epub 2019 Dec 6.

National & Local United Engineering Lab for Personalized Anti-tumor Drugs, The State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, the Graduate School at Shenzhen, Tsinghua University, Shenzhen, PR China.

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http://dx.doi.org/10.1080/17460441.2020.1696769DOI Listing
February 2020

Metabolomics and lipidomics study unveils the impact of polybrominated diphenyl ether-47 on breast cancer mice.

J Hazard Mater 2020 05 13;390:121451. Epub 2019 Oct 13.

State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hong Kong Special Administrative Region, China. Electronic address:

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http://dx.doi.org/10.1016/j.jhazmat.2019.121451DOI Listing
May 2020

Overexpression of lncRNA EPB41L4A-AS1 Induces Metabolic Reprogramming in Trophoblast Cells and Placenta Tissue of Miscarriage.

Mol Ther Nucleic Acids 2019 Dec 26;18:518-532. Epub 2019 Sep 26.

Key Lab in Healthy Science and Technology, Division of Life Science, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, P.R. China; State Key Laboratory of Chemical Oncogenomics, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, P.R. China; Open FIESTA Center, Tsinghua University, Shenzhen 518055, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2019.09.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838551PMC
December 2019

Determination and quantification of fatty acid C=C isomers by epoxidation reaction and liquid chromatography-mass spectrometry.

Anal Chim Acta 2019 Dec 17;1086:82-89. Epub 2019 Aug 17.

State Key Laboratory of Chemical Oncogenomics, Graduate School at Shenzhen, Tsinghua University, Shenzhen, Guangdong, 518055, China; School of Pharmaceutical Sciences, Tsinghua University, Beijing, 100084, China. Electronic address:

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http://dx.doi.org/10.1016/j.aca.2019.08.023DOI Listing
December 2019

One-Step Construction of Fluorenone-Based Donor-Acceptor-Type Conjugated Polymers via Direct Arylation Polymerization for Cell-Imaging Applications.

ACS Appl Mater Interfaces 2019 Aug 30;11(31):28246-28253. Epub 2019 May 30.

The State Key Laboratory of Chemical Oncogenomics, the Graduate School at Shenzhen , Tsinghua University , Shenzhen 518055 , P. R. China.

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http://dx.doi.org/10.1021/acsami.9b04630DOI Listing
August 2019

Discovery of 2-(1-(3-(4-Chloroxyphenyl)-3-oxo- propyl)pyrrolidine-3-yl)-1-benzo[d]imidazole-4-carboxamide: A Potent Poly(ADP-ribose) Polymerase (PARP) Inhibitor for Treatment of Cancer.

Molecules 2019 May 17;24(10). Epub 2019 May 17.

The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China.

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http://dx.doi.org/10.3390/molecules24101901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572064PMC
May 2019

Improvement of the quality of soy sauce by reducing enzyme activity in Aspergillus oryzae.

Food Chem 2019 Sep 15;292:81-89. Epub 2019 Apr 15.

State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science & Technology, No. 29, 13th Avenue, Tianjin Economic and Technological, Tianjin 300457, China. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2019.04.052DOI Listing
September 2019

Label-free fluorescence detection of circulating microRNAs based on duplex-specific nuclease-assisted target recycling coupled with rolling circle amplification.

Talanta 2019 Aug 11;200:480-486. Epub 2019 Jan 11.

Department of Chemistry, Tsinghua University, Beijing 100084, PR China; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, the Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00399140193003
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http://dx.doi.org/10.1016/j.talanta.2019.01.038DOI Listing
August 2019

Development of a versatile DNMT and HDAC inhibitor C02S modulating multiple cancer hallmarks for breast cancer therapy.

Bioorg Chem 2019 06 19;87:200-208. Epub 2019 Mar 19.

Department of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, PR China; National & Local United Engineering Lab for Personalized Anti-tumor Drugs, Shenzhen Kivita Innovative Drug Discovery Institute, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00452068193026
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http://dx.doi.org/10.1016/j.bioorg.2019.03.027DOI Listing
June 2019

LncRNA EPB41L4A-AS1 regulates glycolysis and glutaminolysis by mediating nucleolar translocation of HDAC2.

EBioMedicine 2019 Mar 19;41:200-213. Epub 2019 Feb 19.

State Key Laboratory of Chemical Oncogenomics, Graduate School at Shenzhen, Tsinghua University, Shenzhen, PR China; Key Lab in Healthy Science and Technology, Division of Life Science, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; Open FIESTA Center, Tsinghua University, Shenzhen 518055, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.01.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444057PMC
March 2019

Function, Detection and Alteration of Acylcarnitine Metabolism in Hepatocellular Carcinoma.

Metabolites 2019 Feb 21;9(2). Epub 2019 Feb 21.

State Key Laboratory of Chemical Oncogenomics, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China.

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http://dx.doi.org/10.3390/metabo9020036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410233PMC
February 2019

Naphthalimide-containing conjugated polyelectrolytes with different chain configurations.

Org Biomol Chem 2019 03;17(10):2635-2639

Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China.

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http://dx.doi.org/10.1039/c9ob00219gDOI Listing
March 2019

Evaluation of bisphenol A exposure induced oxidative RNA damage by liquid chromatography-mass spectrometry.

Chemosphere 2019 May 23;222:235-242. Epub 2019 Jan 23.

State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.chemosphere.2019.01.120DOI Listing
May 2019

Discovery of a novel series of hDHODH inhibitors with anti-pulmonary fibrotic activities.

Bioorg Chem 2019 05 7;86:44-51. Epub 2019 Jan 7.

Department of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, PR China; National & Local United Engineering Lab for Personalized Anti-tumor Drugs, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.01.011DOI Listing
May 2019

Isotope Labeling Strategies for Acylcarnitines Profile in Biological Samples by Liquid Chromatography-Mass Spectrometry.

Anal Chem 2019 02 17;91(3):1701-1705. Epub 2019 Jan 17.

State Key Laboratory of Chemical Oncogenomics, Graduate School at Shenzhen , Tsinghua University , Shenzhen , Guangdong 518055 , China.

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http://dx.doi.org/10.1021/acs.analchem.8b05120DOI Listing
February 2019

Recent advances in single cell manipulation and biochemical analysis on microfluidics.

Analyst 2019 Jan;144(3):766-781

State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, P.R. China.

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http://xlink.rsc.org/?DOI=C8AN01186A
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http://dx.doi.org/10.1039/c8an01186aDOI Listing
January 2019

Therapeutic activity of DCC-2036, a novel tyrosine kinase inhibitor, against triple-negative breast cancer patient-derived xenografts by targeting AXL/MET.

Int J Cancer 2019 02 7;144(3):651-664. Epub 2018 Nov 7.

Institute of Clinical Medicine, The First Affiliated Hospital of University of South China, Hengyang, Hunan, China.

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http://doi.wiley.com/10.1002/ijc.31915
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http://dx.doi.org/10.1002/ijc.31915DOI Listing
February 2019

A novel 3D breast-cancer-on-chip platform for therapeutic evaluation of drug delivery systems.

Anal Chim Acta 2018 Dec 15;1036:97-106. Epub 2018 Jun 15.

State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, China; School of Pharmaceutical Sciences, Tsinghua University, Beijing, 100084, China.

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http://dx.doi.org/10.1016/j.aca.2018.06.038DOI Listing
December 2018

Combing metabolomics with bioanalysis methods to study the antitumor mechanism of the new acridone derivative 8q on CCRF-CEM cells: 8q induced mitochondrial-mediated apoptosis and targeted the PI3K/AKT/FOXO1 pathway.

J Pharm Biomed Anal 2018 Oct 8;160:314-322. Epub 2018 Aug 8.

State Key Laboratory of Chemical Oncogenomics, Tsinghua University, Shenzhen 518055, China; School of Medicine, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.jpba.2018.08.016DOI Listing
October 2018

Design, synthesis and anticancer evaluation of acridine hydroxamic acid derivatives as dual Topo and HDAC inhibitors.

Bioorg Med Chem 2018 08 20;26(14):3958-3966. Epub 2018 Jun 20.

State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen, Guangdong 518055, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, PR China.

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http://dx.doi.org/10.1016/j.bmc.2018.06.016DOI Listing
August 2018

Development of Ligand-based Big Data Deep Neural Network Models for Virtual Screening of Large Compound Libraries.

Mol Inform 2018 11 8;37(11):e1800031. Epub 2018 Jun 8.

The State Key Laboratory of Chemical Oncogenomics, the Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, P. R. China.

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http://dx.doi.org/10.1002/minf.201800031DOI Listing
November 2018

Phthalimide conjugations for the degradation of oncogenic PI3K.

Eur J Med Chem 2018 May 26;151:237-247. Epub 2018 Mar 26.

The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing, 100084, PR China; National & Local United Engineering Lab for Personalized Anti-tumor Drugs, The Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.03.066DOI Listing
May 2018

A sensitive colorimetric aptasensor based on trivalent peroxidase-mimic DNAzyme and magnetic nanoparticles.

Anal Chim Acta 2018 Aug 3;1018:86-93. Epub 2018 Feb 3.

State Key Laboratory of Chemical Oncogenomics, The Graduate School at Shenzhen, Tsinghua University, Shenzhen, Guangdong 518055, China; School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.aca.2018.01.040DOI Listing
August 2018

A New Strategy Involving the Use of Peptides and Graphene Oxide for Fluorescence Turn-on Detection of Proteins.

Sensors (Basel) 2018 Jan 29;18(2). Epub 2018 Jan 29.

The State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, the Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China.

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http://dx.doi.org/10.3390/s18020385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855184PMC
January 2018

8u, a pro-apoptosis/cell cycle arrest compound, suppresses invasion and metastasis through HSP90α downregulating and PI3K/Akt inactivation in hepatocellular carcinoma cells.

Sci Rep 2018 01 10;8(1):309. Epub 2018 Jan 10.

State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, China.

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http://dx.doi.org/10.1038/s41598-017-18701-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762664PMC
January 2018

Metabolic profiling on the effect of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in MCF-7 cells.

Chemosphere 2018 Feb 31;192:297-304. Epub 2017 Oct 31.

State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hong Kong Special Administrative Region. Electronic address:

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http://dx.doi.org/10.1016/j.chemosphere.2017.10.170DOI Listing
February 2018

Discovery of 1-(3-aryl-4-chlorophenyl)-3-(p-aryl)urea derivatives against breast cancer by inhibiting PI3K/Akt/mTOR and Hedgehog signalings.

Eur J Med Chem 2017 Dec 6;141:721-733. Epub 2017 Oct 6.

The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing, 100084, PR China; National & Local United Engineering Lab for Personalized Anti-tumor Drugs, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.09.002DOI Listing
December 2017

UBE2J2 promotes hepatocellular carcinoma cell epithelial-mesenchymal transition and invasion .

Oncotarget 2017 Sep 3;8(42):71736-71749. Epub 2017 May 3.

Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China.

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http://dx.doi.org/10.18632/oncotarget.17601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641085PMC
September 2017

Simultaneous quantitation of hydrazine and acetylhydrazine in human plasma by high performance liquid chromatography-tandem mass spectrometry after derivatization with p-tolualdehyde.

J Chromatogr B Analyt Technol Biomed Life Sci 2017 Sep 30;1063:189-195. Epub 2017 Aug 30.

State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China; School of Medicine, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.jchromb.2017.08.036DOI Listing
September 2017

Design, synthesis and biological evaluation of 4-amidobenzimidazole acridine derivatives as dual PARP and Topo inhibitors for cancer therapy.

Eur J Med Chem 2017 Sep 25;138:1135-1146. Epub 2017 Jul 25.

The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing, 100084, PR China; National & Local United Engineering Lab for Personalized Anti-tumor Drugs, The Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234173057
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http://dx.doi.org/10.1016/j.ejmech.2017.07.050DOI Listing
September 2017

Pharmacological relationships and ligand discovery of G protein-coupled receptors revealed by simultaneous ligand and receptor clustering.

J Mol Graph Model 2017 09 11;76:136-142. Epub 2017 Jul 11.

Department of Pharmacy, National University of Singapore, Singapore 117543, Singapore; NUS Graduate School for Integrative Sciences and Engineering, 117456, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.jmgm.2017.06.014DOI Listing
September 2017

Database and Bioinformatics Studies of Probiotics.

J Agric Food Chem 2017 Sep 22;65(35):7599-7606. Epub 2017 Aug 22.

Bioinformatics and Drug Design Group, Department of Pharmacy, and Center for Computational Science and Engineering, National University of Singapore , Singapore 117543.

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http://dx.doi.org/10.1021/acs.jafc.7b01815DOI Listing
September 2017

Predicting the Enzymatic Hydrolysis Half-lives of New Chemicals Using Support Vector Regression Models Based on Stepwise Feature Elimination.

Mol Inform 2017 11 19;36(11). Epub 2017 Jun 19.

The State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, the Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, P. R. China.

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http://doi.wiley.com/10.1002/minf.201600153
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http://dx.doi.org/10.1002/minf.201600153DOI Listing
November 2017

Olaparib hydroxamic acid derivatives as dual PARP and HDAC inhibitors for cancer therapy.

Bioorg Med Chem 2017 08 31;25(15):4100-4109. Epub 2017 May 31.

The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, PR China; National & Local United Engineering Lab for Personalized Anti-tumor Drugs, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680896173033
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http://dx.doi.org/10.1016/j.bmc.2017.05.058DOI Listing
August 2017

AKT and its related molecular feature in aged mice skin.

PLoS One 2017 7;12(6):e0178969. Epub 2017 Jun 7.

Tsinghua Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178969PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462418PMC
September 2017

Design, synthesis and evaluation of azaacridine derivatives as dual-target EGFR and Src kinase inhibitors for antitumor treatment.

Eur J Med Chem 2017 Aug 11;136:372-381. Epub 2017 May 11.

The Guangdong Province Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; National & Local United Engineering Lab for Personalized Antitumor Drugs, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; School of Medicine, Tsinghua University, Beijing 100084, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.05.006DOI Listing
August 2017

Synthesis and biological research of novel azaacridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.

Bioorg Med Chem 2017 07 4;25(13):3437-3446. Epub 2017 May 4.

The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; National & Local United Engineering Lab for Personalized Anti-tumor Drugs, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.04.030DOI Listing
July 2017

Conjugated polyelectrolytes with galactose-containing side chains for targeted hepatoma cell imaging.

Chem Commun (Camb) 2017 May;53(41):5625-5628

Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China.

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http://xlink.rsc.org/?DOI=C7CC02363D
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http://dx.doi.org/10.1039/c7cc02363dDOI Listing
May 2017

Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors.

Eur J Med Chem 2017 Jul 12;134:281-292. Epub 2017 Apr 12.

The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, PR China; National & Local United Engineering Lab for Personalized Anti-tumor Drugs, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.04.017DOI Listing
July 2017

A simple and sensitive aptasensor for colorimetric detection of adenosine triphosphate based on unmodified gold nanoparticles.

Talanta 2017 Jun 4;168:279-285. Epub 2017 Mar 4.

The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, the Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. Electronic address:

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http://dx.doi.org/10.1016/j.talanta.2017.03.014DOI Listing
June 2017

The Optimization and Characterization of an RNA-Cleaving Fluorogenic DNAzyme Probe for MDA-MB-231 Cell Detection.

Sensors (Basel) 2017 Mar 21;17(3). Epub 2017 Mar 21.

Department of Chemistry, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.3390/s17030650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375936PMC
March 2017

Light-Induced Translocation of a Conjugated Polyelectrolyte in Cells: From Fluorescent Probe to Anticancer Agent.

ACS Appl Mater Interfaces 2017 Mar 17;9(12):10512-10518. Epub 2017 Mar 17.

Department of Chemistry and ‡School of Pharmaceutical Sciences, Tsinghua University , Beijing 100084, P. R. China.

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http://dx.doi.org/10.1021/acsami.7b00540DOI Listing
March 2017

An iminodiacetate-modified conjugated polyelectrolyte for fluorescent labeling of histidine-tagged proteins.

Chem Commun (Camb) 2017 Apr;53(30):4191-4194

Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China.

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http://dx.doi.org/10.1039/c7cc00850cDOI Listing
April 2017

Novel multi-substituted benzyl acridone derivatives as survivin inhibitors for hepatocellular carcinoma treatment.

Eur J Med Chem 2017 Mar 17;129:337-348. Epub 2017 Feb 17.

Department of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, PR China; National & Local United Engineering Lab for Personalized Anti-tumor Drugs, The Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing, 100084, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.02.027DOI Listing
March 2017

A Genome-Wide Association Study Identifies Genetic Variants Associated with Mathematics Ability.

Sci Rep 2017 02 3;7:40365. Epub 2017 Feb 3.

CapitalBio eHealth Science &Technology (Beijing) Co., Ltd., Beijing, 102206, China.

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http://dx.doi.org/10.1038/srep40365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290743PMC
February 2017

Predicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway.

Sci Rep 2017 01 19;7:40752. Epub 2017 Jan 19.

Department of Pharmacy, and Center for Computational Science and Engineering, National University of Singapore, Blk S16, Level 8, 3 Science Drive 2, 117543 Singapore.

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http://www.nature.com/articles/srep40752
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http://dx.doi.org/10.1038/srep40752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244366PMC
January 2017

PARP inhibitors as antitumor agents: a patent update (2013-2015).

Expert Opin Ther Pat 2017 Mar 21;27(3):363-382. Epub 2016 Nov 21.

b The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, the Graduate School at Shenzhen , Tsinghua University , Shenzhen , P. R. China.

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http://dx.doi.org/10.1080/13543776.2017.1259413DOI Listing
March 2017

NEAT1 modulates herpes simplex virus-1 replication by regulating viral gene transcription.

Cell Mol Life Sci 2017 03 25;74(6):1117-1131. Epub 2016 Oct 25.

Key Lab in Healthy Science and Technology, Division of Life Science, Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, People's Republic of China.

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http://dx.doi.org/10.1007/s00018-016-2398-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309293PMC
March 2017

Synthesis and investigation of novel 6-(1,2,3-triazol-4-yl)-4-aminoquinazolin derivatives possessing hydroxamic acid moiety for cancer therapy.

Bioorg Med Chem 2017 01 10;25(1):27-37. Epub 2016 Oct 10.

The State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; School of Medicine, Tsinghua University, Beijing 100084, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.10.006DOI Listing
January 2017

Simultaneous bioimaging recognition of Al and Cu in living-cell, and further detection of F and S by a simple fluorogenic benzimidazole-based chemosensor.

Talanta 2016 Dec 22;161:309-319. Epub 2016 Aug 22.

Department of Chemistry, Tsinghua University, Beijing 100084, PR China; The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen, Guangdong 518055, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.talanta.2016.08.061DOI Listing
December 2016

Surface-printed microdot array chips coupled with matrix-assisted laser desorption/ionization mass spectrometry for high-throughput single-cell patterning and phospholipid analysis.

Rapid Commun Mass Spectrom 2016 08;30 Suppl 1:73-9

Key Laboratory of Metabolomics at Shenzhen, Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, China.

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http://dx.doi.org/10.1002/rcm.7628DOI Listing
August 2016

Conjugated Polyelectrolyte Nanoparticles for Apoptotic Cell Imaging.

ACS Appl Mater Interfaces 2016 Aug 16;8(34):21984-9. Epub 2016 Aug 16.

The Ministry-Province Jointly Constructed Base for State Key Lab - Shenzhen Key Laboratory of Chemical Biology, the Graduate School at Shenzhen, Tsinghua University , Shenzhen 518055, P. R. China.

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http://dx.doi.org/10.1021/acsami.6b09347DOI Listing
August 2016

Development of a blood-brain barrier model in a membrane-based microchip for characterization of drug permeability and cytotoxicity for drug screening.

Anal Chim Acta 2016 Aug 24;934:186-93. Epub 2016 Jun 24.

State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; Department of Chemistry, Tsinghua University, Beijing 100084, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.aca.2016.06.028DOI Listing
August 2016

Hair Follicle and Sebaceous Gland De Novo Regeneration With Cultured Epidermal Stem Cells and Skin-Derived Precursors.

Stem Cells Transl Med 2016 12 25;5(12):1695-1706. Epub 2016 Jul 25.

Shenzhen Key Laboratory of Health Sciences and Technology, Graduate School at Shenzhen, Tsinghua University, Beijing, People's Republic of China

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http://dx.doi.org/10.5966/sctm.2015-0397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189649PMC
December 2016

Fluorescence array-based sensing of nitroaromatics using conjugated polyelectrolytes.

Analyst 2016 May;141(11):3242-5

The Ministry-Province Jointly Constructed Base for State Key Lab- Shenzhen Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, P. R. China. and Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, P. R. China.

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http://dx.doi.org/10.1039/c6an00678gDOI Listing
May 2016

Current Progresses and Trends in the Development of Progesterone Receptor Modulators.

Curr Med Chem 2016 ;23(23):2507-54

Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory, the Graduate School at Shenzhen, Tsinghua University, Shenzhen, P.R. China.

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http://dx.doi.org/10.2174/0929867323666160428105310DOI Listing
February 2017

Carbon Dots and 9AA as a Binary Matrix for the Detection of Small Molecules by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry.

J Am Soc Mass Spectrom 2016 07 13;27(7):1227-35. Epub 2016 Apr 13.

National and Local United Engineering Laboratory for Personalized Antitumor Drugs, Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, China.

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http://dx.doi.org/10.1007/s13361-016-1396-yDOI Listing
July 2016

Synthesis and antiproliferative activity of 9-benzylamino-6-chloro-2-methoxy-acridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.

Eur J Med Chem 2016 Jun 28;116:59-70. Epub 2016 Mar 28.

Tsinghua University, Department of Chemistry, Beijing 100084, PR China; The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518-55, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2016.03.066DOI Listing
June 2016

MALDI imaging for the localization of saponins in root tissues and rapid differentiation of three Panax herbs.

Electrophoresis 2016 07 2;37(13):1956-66. Epub 2016 May 2.

State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen, P. R. China.

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http://dx.doi.org/10.1002/elps.201600027DOI Listing
July 2016

Exposure of CCRF-CEM cells to acridone derivative 8a triggers tumor death via multiple mechanisms.

Proteomics 2016 Apr 14;16(7):1177-90. Epub 2016 Mar 14.

The State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen, P. R. China.

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http://dx.doi.org/10.1002/pmic.201500317DOI Listing
April 2016

Metabolomics study on the antitumor effect of marine natural compound flexibilide in HCT-116 colon cancer cell line.

J Chromatogr B Analyt Technol Biomed Life Sci 2016 Mar 8;1014:17-23. Epub 2016 Jan 8.

State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China; Key Laboratory of Metabolomics at Shenzhen, Shenzhen 518055, China. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2016.01.003DOI Listing
March 2016

Proteolysis targeting peptide (PROTAP) strategy for protein ubiquitination and degradation.

Biochem Biophys Res Commun 2016 Feb 28;470(4):936-40. Epub 2016 Jan 28.

The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, Guangdong, China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.bbrc.2016.01.158DOI Listing
February 2016

Matrix-assisted laser desorption/ionization mass spectrometry imaging of cell cultures for the lipidomic analysis of potential lipid markers in human breast cancer invasion.

Rapid Commun Mass Spectrom 2016 Feb;30(4):533-42

State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, China.

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http://dx.doi.org/10.1002/rcm.7466DOI Listing
February 2016

Design, synthesis and evaluation of acridine derivatives as multi-target Src and MEK kinase inhibitors for anti-tumor treatment.

Bioorg Med Chem 2016 Jan 8;24(2):261-9. Epub 2015 Dec 8.

The Guangdong Province Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; National & Local United Engineering Lab for Personalized Anti-tumor Drugs, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; School of Medicine, Tsinghua University, Beijing 100084, PR China.

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http://dx.doi.org/10.1016/j.bmc.2015.12.011DOI Listing
January 2016

A Graphene-Based Biosensing Platform Based on Regulated Release of an Aptameric DNA Biosensor.

Sensors (Basel) 2015 Nov 9;15(11):28244-56. Epub 2015 Nov 9.

The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, the Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China.

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http://dx.doi.org/10.3390/s151128244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701278PMC
November 2015

Drug cytotoxicity and signaling pathway analysis with three-dimensional tumor spheroids in a microwell-based microfluidic chip for drug screening.

Anal Chim Acta 2015 Oct 22;898:85-92. Epub 2015 Oct 22.

School of Medicine, Tsinghua University, Beijing 100084, China; State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. Electronic address:

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http://dx.doi.org/10.1016/j.aca.2015.10.006DOI Listing
October 2015

Localization of ginsenosides in Panax ginseng with different age by matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry imaging.

J Chromatogr B Analyt Technol Biomed Life Sci 2016 Jul 23;1026:263-271. Epub 2015 Oct 23.

State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2015.09.024DOI Listing
July 2016

Sensitive Conjugated-Polymer-Based Fluorescent ATP Probes and Their Application in Cell Imaging.

ACS Appl Mater Interfaces 2016 Feb 22;8(6):3567-74. Epub 2015 Sep 22.

The Ministry-Province Jointly Constructed Base for State Key Lab, Shenzhen Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University , Shenzhen 518055, P. R. China.

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http://dx.doi.org/10.1021/acsami.5b06935DOI Listing
February 2016

A Catalytic DNA Probe with Stem-loop Motif for Human T47D Breast Cancer Cells.

Anal Sci 2015 ;31(8):815-22

Department of Chemistry, Tsinghua University.

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http://dx.doi.org/10.2116/analsci.31.815DOI Listing
May 2016

Excess Integrins Cause Lung Entrapment of Mesenchymal Stem Cells.

Stem Cells 2015 Nov 24;33(11):3315-26. Epub 2015 Jul 24.

The Shenzhen Key Laboratory of Health Sciences and Technology, Graduate School at Shenzhen, Tsinghua University, Shenzhen, People's Republic of China.

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http://dx.doi.org/10.1002/stem.2087DOI Listing
November 2015

Study of Phospholipids in Single Cells Using an Integrated Microfluidic Device Combined with Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry.

Anal Chem 2015 Jul 2;87(14):7052-9. Epub 2015 Jul 2.

‡State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China.

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http://dx.doi.org/10.1021/acs.analchem.5b00010DOI Listing
July 2015

Synthesis and antiproliferative activity of 2,7-diamino l0-(3,5-dimethoxy)benzyl-9(10H)-acridone derivatives as potent telomeric G-quadruplex DNA ligands.

Bioorg Chem 2015 Jun 17;60:30-6. Epub 2015 Apr 17.

The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518-55, PR China; National & Local United Engineering Lab for Personalized Anti-Tumor Drugs, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, PR China.

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http://dx.doi.org/10.1016/j.bioorg.2015.04.002DOI Listing
June 2015

Optimal DNA templates for rolling circle amplification revealed by in vitro selection.

Chemistry 2015 May 15;21(22):8069-74. Epub 2015 Apr 15.

Departments of Biochemistry and Biomedical Sciences and Chemistry and Chemical Biology, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4K1 (Canada).

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http://dx.doi.org/10.1002/chem.201500994DOI Listing
May 2015

Clustered distribution of natural product leads of drugs in the chemical space as influenced by the privileged target-sites.

Sci Rep 2015 Mar 20;5:9325. Epub 2015 Mar 20.

1] Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, the Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, the Graduate School at Shenzhen, Tsinghua University, Shenzhen, and Shenzhen Technology and Engineering Laboratory for Personalized Cancer Diagnostics and Therapeutics, PO Box 518000, P. R. China [2] Bioinformatics and Drug Design Group, Department of Pharmacy, and Center for Computational Science and Engineering, National University of Singapore, Singapore 117543 [3] NUS Graduate School for Integrative Sciences and Engineering, Singapore 117456.

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http://dx.doi.org/10.1038/srep09325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380136PMC
March 2015

Synthesis and biological evaluation of benzimidazole acridine derivatives as potential DNA-binding and apoptosis-inducing agents.

Bioorg Med Chem 2015 Apr 24;23(8):1800-7. Epub 2015 Feb 24.

The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, Shenzhen 518055, PR China; National & Local United Engineering Lab for Personalized Anti-tumor Drugs, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; School of Medicine, Tsinghua University, Beijing 100084, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680896150013
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http://dx.doi.org/10.1016/j.bmc.2015.02.036DOI Listing
April 2015

Genome-wide association study identifies a new susceptibility locus for cleft lip with or without a cleft palate.

Nat Commun 2015 Mar 16;6:6414. Epub 2015 Mar 16.

1] General Hospital of Ningxia Medical University, Yinchuan 750004, China [2] National Engineering Research Center for Beijing Biochip Technology, Sub-center in Ningxia, Yinchuan 750004, China.

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http://dx.doi.org/10.1038/ncomms7414DOI Listing
March 2015

Fluorescence array-based sensing of metal ions using conjugated polyelectrolytes.

ACS Appl Mater Interfaces 2015 Apr 17;7(12):6882-8. Epub 2015 Mar 17.

‡The Ministry-Province Jointly Constructed Base for State Key Lab- Shenzhen Key Laboratory of Chemical Biology, the Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, P. R. China.

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http://dx.doi.org/10.1021/acsami.5b00587DOI Listing
April 2015

A novel method of liquid chromatography-tandem mass spectrometry combined with chemical derivatization for the determination of ribonucleosides in urine.

Anal Chim Acta 2015 Mar 30;864:30-8. Epub 2015 Jan 30.

State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hong Kong, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00032670150010
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http://dx.doi.org/10.1016/j.aca.2015.01.044DOI Listing
March 2015

Molecular design, synthesis and biological research of novel pyridyl acridones as potent DNA-binding and apoptosis-inducing agents.

Eur J Med Chem 2015 Mar 7;93:214-26. Epub 2015 Feb 7.

The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, Shenzhen 518055, PR China; Shenzhen Anti-Tumor Drug Development Engineering Laboratory, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, PR China; School of Medicine, Tsinghua University, Beijing 100084, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2015.02.003DOI Listing
March 2015

Stable isotope labeling strategy for curcumin metabolite study in human liver microsomes by liquid chromatography-tandem mass spectrometry.

J Am Soc Mass Spectrom 2015 Apr 16;26(4):686-94. Epub 2015 Jan 16.

State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, China.

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http://link.springer.com/content/pdf/10.1007/s13361-014-1064
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http://link.springer.com/10.1007/s13361-014-1064-z
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http://dx.doi.org/10.1007/s13361-014-1064-zDOI Listing
April 2015

TGF-β1 induces HMGA1 expression in human breast cancer cells: implications of the involvement of HMGA1 in TGF-β signaling.

Int J Mol Med 2015 Mar 5;35(3):693-701. Epub 2015 Jan 5.

Guangdong Provincial Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen, Guangdong 518055, P.R. China.

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https://www.spandidos-publications.com/10.3892/ijmm.2015.206
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http://dx.doi.org/10.3892/ijmm.2015.2062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314408PMC
March 2015

Examination of bacterial inhibition using a catalytic DNA.

PLoS One 2014 22;9(12):e115640. Epub 2014 Dec 22.

Department of Biochemistry and Biomedical Sciences & Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115640PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274092PMC
December 2015

Highly specific recognition of breast tumors by an RNA-cleaving fluorogenic DNAzyme probe.

Anal Chem 2015 Jan 17;87(1):569-77. Epub 2014 Dec 17.

Department of Chemistry, Tsinghua University , Beijing, 100084, China.

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http://dx.doi.org/10.1021/ac5031557DOI Listing
January 2015

Multitarget inhibitors derived from crosstalk mechanism involving VEGFR2.

Future Med Chem 2014 ;6(16):1771-89

Department of Chemistry, Tsinghua University, Beijing 100084, PR China.

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http://dx.doi.org/10.4155/fmc.14.112DOI Listing
August 2015

Association study of developmental dyslexia candidate genes DCDC2 and KIAA0319 in Chinese population.

Am J Med Genet B Neuropsychiatr Genet 2014 Dec 17;165B(8):627-34. Epub 2014 Sep 17.

The State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, The Graduate School at Shenzhen, Tsinghua University, Shenzhen, China; Medical Systems Biology Research Center, Department of Biomedical Engineering, Tsinghua University School of Medicine, Beijing, China; National Engineering Research Center for Beijing Biochip Technology, Beijing, China; CapitalBio Corporation, Beijing, China.

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http://dx.doi.org/10.1002/ajmg.b.32267DOI Listing
December 2014