Yutaka Tamura

Yutaka Tamura

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Prevalence and characterization of Clostridioides difficile isolates from retail food products (vegetables and meats) in Japan.

Anaerobe 2020 Feb 26;61:102132. Epub 2019 Nov 26.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido, Japan.

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http://dx.doi.org/10.1016/j.anaerobe.2019.102132DOI Listing
February 2020

Manure Compost Is a Potential Source of Tetracycline-Resistant and Tetracycline Resistance Genes in Japanese Farms.

Antibiotics (Basel) 2020 Feb 11;9(2). Epub 2020 Feb 11.

Laboratory of Food Microbiology and Food Safety, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu 069-8501, Japan.

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http://dx.doi.org/10.3390/antibiotics9020076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168215PMC
February 2020

Target protein-oriented isolation of Hes1 dimer inhibitors using protein based methods.

Sci Rep 2020 Jan 28;10(1):1381. Epub 2020 Jan 28.

Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8675, Japan.

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http://dx.doi.org/10.1038/s41598-020-58451-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987128PMC
January 2020

Screening of hospital-manhole sewage using MacConkey agar with cefotaxime reveals extended-spectrum β-lactamase (ESBL)-producing Escherichia coli.

Int J Antimicrob Agents 2019 Dec 6;54(6):831-833. Epub 2019 Aug 6.

Department of Medical Laboratory Science, Faculty of Health Sciences, Hokkaido University Graduate School of Health Sciences, Nishi-5 Kita-12 Jo Kitaku, Sapporo 060-0812, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ijantimicag.2019.08.004DOI Listing
December 2019

Prevalence and characterization of Staphylococcus aureus isolated in raw milk from cows in Hokkaido, Japan.

Trop Anim Health Prod 2019 Dec 16. Epub 2019 Dec 16.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido, Japan.

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http://dx.doi.org/10.1007/s11250-019-02169-6DOI Listing
December 2019

Prevalence of Extended-Spectrum β-Lactamase-Producing Bacteria on Fresh Vegetables in Japan.

J Food Prot 2019 Oct;82(10):1663-1666

School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunkyodai, Ebetsu, Hokkaido 069-8501, Japan (ORCID: https://orcid.org/0000-0003-1624-1469 [M.U.]).

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http://dx.doi.org/10.4315/0362-028X.JFP-19-138DOI Listing
October 2019

Analysis host-recognition mechanism of staphylococcal kayvirus ɸSA039 reveals a novel strategy that protects Staphylococcus aureus against infection by Staphylococcus pseudintermedius Siphoviridae phages.

Appl Microbiol Biotechnol 2019 Aug 25;103(16):6809-6823. Epub 2019 Jun 25.

School of Life Science and Technology, Tokyo Institute of Technology, 4259 J2-15 Nagatsuta-cho, Midori-ku, Yokohama, 226-8501, Japan.

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http://dx.doi.org/10.1007/s00253-019-09940-7DOI Listing
August 2019

Detection of the sul2-strA-strB gene cluster in an ice core from Dome Fuji Station, East Antarctica.

J Glob Antimicrob Resist 2019 06 20;17:72-78. Epub 2018 Nov 20.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, Graduate School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu 069-0834, Hokkaido, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jgar.2018.11.005DOI Listing
June 2019

Zinc Acetate Potentiates the Action of Tosufloxacin against Escherichia coli Biofilm Persisters.

Antimicrob Agents Chemother 2019 06 24;63(6). Epub 2019 May 24.

Institut Pasteur, Genetics of Biofilm Unit, Department of Microbiology, Paris, France

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http://aac.asm.org/lookup/doi/10.1128/AAC.00069-19
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http://dx.doi.org/10.1128/AAC.00069-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535537PMC
June 2019

Prevalence of 16S rRNA methylases in Gram-negative bacteria derived from companion animals and livestock in Japan.

J Vet Med Sci 2019 Jun 2;81(6):874-878. Epub 2019 May 2.

Laboratory of Food Microbiology and Food Safety, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.

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http://dx.doi.org/10.1292/jvms.19-0144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612502PMC
June 2019

Synthesis and Evaluation of Fuligocandin B Derivatives with Activity for Overcoming TRAIL Resistance.

Chem Pharm Bull (Tokyo) 2018 ;66(8):810-817

Graduate School of Pharmaceutical Sciences, Chiba University.

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http://dx.doi.org/10.1248/cpb.c18-00308DOI Listing
May 2019

Role of Flies in the Maintenance of Antimicrobial Resistance in Farm Environments.

Microb Drug Resist 2019 Jan/Feb;25(1):127-132. Epub 2018 Apr 30.

1 Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University , Hokkaido, Japan .

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http://dx.doi.org/10.1089/mdr.2017.0371DOI Listing
April 2019

Quantitative Analysis of Houseflies-mediated Food Contamination with Bacteria.

Food Saf (Tokyo) 2019 Mar 29;7(1):11-14. Epub 2019 Mar 29.

Laboratory of Food Microbiology and Food Safety, School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunkyodai, Ebetsu, Hokkaido 069-8501, Japan.

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http://dx.doi.org/10.14252/foodsafetyfscj.2018013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977770PMC
March 2019

Inhibition effect of flavophospholipol on conjugative transfer of the extended-spectrum β-lactamase and vanA genes.

J Antibiot (Tokyo) 2019 02 25;72(2):79-85. Epub 2018 Oct 25.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.

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http://www.nature.com/articles/s41429-018-0113-4
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http://dx.doi.org/10.1038/s41429-018-0113-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760635PMC
February 2019

Deletion of Eqtn in mice reduces male fertility and sperm-egg adhesion.

Reproduction 2018 12;156(6):579-590

Department of Functional Anatomy, Reproductive Biology and Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.

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https://rep.bioscientifica.com/view/journals/rep/aop/rep-18-
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http://dx.doi.org/10.1530/REP-18-0394DOI Listing
December 2018

GLI1 Inhibitors Identified by Target Protein Oriented Natural Products Isolation (TPO-NAPI) with Hedgehog Inhibition.

ACS Chem Biol 2018 09 7;13(9):2551-2559. Epub 2018 Sep 7.

Graduate School of Pharmaceutical Sciences , Chiba University , 1-8-1 Inohana , Chuo-ku , Chiba 260-8675 , Japan.

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http://dx.doi.org/10.1021/acschembio.8b00492DOI Listing
September 2018

Co-harboring of cephalosporin (bla)/colistin (mcr) resistance genes among Enterobacteriaceae from flies in Thailand.

FEMS Microbiol Lett 2018 08;365(16)

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunkyodai, Ebetsu, Hokkaido 069-8501 Japan.

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https://academic.oup.com/femsle/article/doi/10.1093/femsle/f
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http://dx.doi.org/10.1093/femsle/fny178DOI Listing
August 2018

Prevalence of methicillin-resistant Staphylococcus aureus among veterinary staff in small animal hospitals in Sapporo, Japan, between 2008 and 2016: A follow up study.

J Infect Chemother 2018 Jul 28;24(7):588-591. Epub 2018 Feb 28.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunkyodai, Ebetsu, Hokkaido, 069-8501 Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jiac.2018.01.016DOI Listing
July 2018

Isolation of a mcr-1-harbouring Escherichia coli isolate from a human clinical setting in Sapporo, Japan.

J Glob Antimicrob Resist 2018 06 21;13:20-21. Epub 2018 Feb 21.

Department of Microbiology, Sapporo Medical University School of Medicine, Sapporo, Japan.

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http://dx.doi.org/10.1016/j.jgar.2018.02.010DOI Listing
June 2018

Species distribution, virulence factors, and antimicrobial resistance of Acinetobacter spp. isolates from dogs and cats: a preliminary study.

Microbiol Immunol 2018 May 12. Epub 2018 May 12.

The United Graduate School of Veterinary Science, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan.

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http://dx.doi.org/10.1111/1348-0421.12601DOI Listing
May 2018

Isolation and molecular characterization of a urease-negative Actinobacillus pleuropneumoniae mutant.

J Vet Diagn Invest 2018 Jan 16;30(1):172-174. Epub 2017 Nov 16.

The National Institute of Animal Health, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan (Ito).

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http://dx.doi.org/10.1177/1040638717742436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504136PMC
January 2018

High prevalence of mcr-1, mcr-3 and mcr-5 in Escherichia coli derived from diseased pigs in Japan.

Int J Antimicrob Agents 2018 01 26;51(1):163-164. Epub 2017 Nov 26.

Laboratory of Food Microbiology and Food Safety, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ijantimicag.2017.11.010DOI Listing
January 2018

PGE and E show lower efficacies than E to β-catenin-mediated activity as biased ligands of EP4 prostanoid receptors.

FEBS Lett 2017 11 12;591(22):3771-3780. Epub 2017 Nov 12.

Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences and Graduate School of Biomedical Sciences, Tokushima University, Japan.

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http://dx.doi.org/10.1002/1873-3468.12878DOI Listing
November 2017

Closely related methicillin-resistant Staphylococcus aureus isolates from retail meat, cows with mastitis, and humans in Japan.

PLoS One 2017 30;12(10):e0187319. Epub 2017 Oct 30.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187319PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662215PMC
November 2017

Quinolone Resistance Determinants of Clinical Salmonella Enteritidis in Thailand.

Microb Drug Resist 2017 Oct 23;23(7):885-894. Epub 2017 Feb 23.

2 Division of Bioresources, Hokkaido University Research Center for Zoonosis Control , Sapporo, Japan .

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http://dx.doi.org/10.1089/mdr.2015.0234DOI Listing
October 2017

is highly prevalent among houseflies ().

J Med Microbiol 2017 Aug;66(8):1202-1206

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan.

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http://dx.doi.org/10.1099/jmm.0.000556DOI Listing
August 2017

Antimicrobial Resistance of Pseudomonas aeruginosa Isolated from Dogs and Cats in Primary Veterinary Hospitals in Japan.

Jpn J Infect Dis 2017 Jul 28;70(4):461-463. Epub 2017 Mar 28.

Laboratory of Food Microbiology and Food Safety, School of Veterinary Medicine, Rakuno Gakuen University.

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http://dx.doi.org/10.7883/yoken.JJID.2016.536DOI Listing
July 2017

Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA.

Microbiol Immunol 2017 Jun;61(6):215-224

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, 582 Bunkyoudai-Midorimachi, Ebetsu, 069-8501, Japan.

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http://doi.wiley.com/10.1111/1348-0421.12490
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http://dx.doi.org/10.1111/1348-0421.12490DOI Listing
June 2017

Molecular epidemiological analysis of human- and chicken-derived isolates of Campylobacter jejuni in Japan using next-generation sequencing.

J Infect Chemother 2017 Mar 10;23(3):165-172. Epub 2017 Jan 10.

Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S1341321X163026
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http://dx.doi.org/10.1016/j.jiac.2016.11.011DOI Listing
March 2017

Survival and prevalence of Clostridium difficile in manure compost derived from pigs.

Anaerobe 2017 Feb 18;43:15-20. Epub 2016 Nov 18.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.anaerobe.2016.11.004DOI Listing
February 2017

Human DP and EP2 prostanoid receptors take on distinct forms depending on the diverse binding of different ligands.

FEBS J 2016 11 29;283(21):3931-3940. Epub 2016 Sep 29.

Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Japan.

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http://dx.doi.org/10.1111/febs.13899DOI Listing
November 2016

Impact of mutations in DNA gyrase genes on quinolone resistance in Campylobacter jejuni.

Drug Test Anal 2016 Oct 9;8(10):1071-1076. Epub 2016 Feb 9.

Division of Bioresources, Hokkaido University Research Center for Zoonosis Control, Sapporo, Japan.

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http://dx.doi.org/10.1002/dta.1937DOI Listing
October 2016

Phage Therapy Is Effective in a Mouse Model of Bacterial Equine Keratitis.

Appl Environ Microbiol 2016 09 15;82(17):5332-9. Epub 2016 Aug 15.

Laboratory of Food Microbiology and Food Safety, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan.

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http://dx.doi.org/10.1128/AEM.01166-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988198PMC
September 2016

Bacteriophage can lyse antibiotic-resistant Pseudomonas aeruginosa isolated from canine diseases.

J Vet Med Sci 2016 Jul 14;78(6):1035-8. Epub 2016 Feb 14.

Laboratory of Veterinary Biochemistry, School of Veterinary Medicine, Rakuno Gakuen University, 582 Bunkyodai-Midorimachi Ebetsu, Hokkaido 069-8501, Japan.

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http://dx.doi.org/10.1292/jvms.15-0310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937139PMC
July 2016

Effects of novel small compounds targeting TrkB on neuronal cell survival and depression-like behavior.

Neurochem Int 2016 07 7;97:42-8. Epub 2016 May 7.

Saga-ken Medical Center Koseikan, Saga 840-8571, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neuint.2016.04.017DOI Listing
July 2016

Horizontal Transfer of Plasmid-Mediated Cephalosporin Resistance Genes in the Intestine of Houseflies (Musca domestica).

Microb Drug Resist 2016 Jun 18;22(4):336-41. Epub 2015 Dec 18.

Laboratory of Food Microbiology and Food Safety, School of Veterinary Medicine, Rakuno Gakuen University , Ebetsu, Japan .

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http://www.liebertpub.com/doi/10.1089/mdr.2015.0125
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http://dx.doi.org/10.1089/mdr.2015.0125DOI Listing
June 2016

Complete Genome Sequences of Broad-Host-Range Pseudomonas aeruginosa Bacteriophages ΦR18 and ΦS12-1.

Genome Announc 2016 May 5;4(3). Epub 2016 May 5.

Laboratory of Food Microbiology and Food Safety, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.

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http://dx.doi.org/10.1128/genomeA.00041-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859162PMC
May 2016

Decreases in body temperature and body mass constitute pre-hibernation remodelling in the Syrian golden hamster, a facultative mammalian hibernator.

R Soc Open Sci 2016 Apr 13;3(4):160002. Epub 2016 Apr 13.

Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan; Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Chiyoda-ku, Tokyo 102-0076, Japan.

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http://dx.doi.org/10.1098/rsos.160002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852639PMC
April 2016

Distribution and characterization of Clostridium difficile isolated from dogs in Japan.

Anaerobe 2016 Feb 9;37:58-61. Epub 2015 Oct 9.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.anaerobe.2015.10.002DOI Listing
February 2016

Hes1 inhibitor isolated by target protein oriented natural products isolation (TPO-NAPI) of differentiation activators of neural stem cells.

Chem Sci 2016 Feb 1;7(2):1514-1520. Epub 2015 Dec 1.

Graduate School of Pharmaceutical Sciences , Chiba University , 1-8-1 Inohana, Chuo-ku , Chiba 260-8675 , Japan . Email: ; Email:

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http://dx.doi.org/10.1039/c5sc03540fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963671PMC
February 2016

Multivariable Analysis of the Association Between Antimicrobial Use and Antimicrobial Resistance in Escherichia coli Isolated from Apparently Healthy Pigs in Japan.

Microb Drug Resist 2016 Jan 21;22(1):28-39. Epub 2015 Aug 21.

4 Food Hygiene, Division of Health and Environmental Sciences, Department of Veterinary Medicine, School of Veterinary Medicine, Rakuno Gakuen University , Ebetsu, Japan .

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http://dx.doi.org/10.1089/mdr.2014.0311DOI Listing
January 2016

Liposomally formulated phospholipid-conjugated indocyanine green for intra-operative brain tumor detection and resection.

Int J Pharm 2015 Dec 23;496(2):401-6. Epub 2015 Oct 23.

Department of Bioinformatics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan; Molecular Chirality Research Center, Chiba University, Chiba 263-8522, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2015.10.001DOI Listing
December 2015

Characterisation of meticillin-resistant Staphylococcus aureus ST97 and ST5 isolated from pigs in Japan.

J Glob Antimicrob Resist 2015 Dec 29;3(4):283-285. Epub 2015 Aug 29.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22137165150008
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http://dx.doi.org/10.1016/j.jgar.2015.07.009DOI Listing
December 2015

The Role of Flies in Disseminating Plasmids with Antimicrobial-Resistance Genes Between Farms.

Microb Drug Resist 2015 Oct 20;21(5):562-9. Epub 2015 May 20.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University , Hokkaido, Japan .

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http://dx.doi.org/10.1089/mdr.2015.0033DOI Listing
October 2015

Rapid detection of Salmonella enterica serovar Typhimurium DT104 strains by the polymerase chain reaction.

Acta Vet Scand 2015 Sep 25;57:59. Epub 2015 Sep 25.

Hokkaido Research Station, National Institute of Animal Health, 4 Hitsujigaoka, Toyohira, Sapporo, 062-0045, Japan.

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http://www.actavetscand.com/content/57/1/59
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http://dx.doi.org/10.1186/s13028-015-0143-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583067PMC
September 2015

Characterization of Campylobacter jejuni DNA gyrase as the target of quinolones.

J Infect Chemother 2015 Aug 23;21(8):604-9. Epub 2015 May 23.

Division of Bioresources, Hokkaido University Research Center for Zoonosis Control, Sapporo, Japan; Hokkaido University, The Global Station for Zoonosis Control, Sapporo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jiac.2015.05.003DOI Listing
August 2015

Association of veterinary third-generation cephalosporin use with the risk of emergence of extended-spectrum-cephalosporin resistance in Escherichia coli from dairy cattle in Japan.

PLoS One 2014 22;9(4):e96101. Epub 2014 Apr 22.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0096101PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995961PMC
January 2015

High prevalence of cross-resistance to aminoglycosides in fluoroquinolone-resistant Escherichia coli clinical isolates.

Chemotherapy 2013 13;59(5):379-84. Epub 2014 May 13.

Department of Microbiology, Sapporo Medical University School of Medicine, Sapporo, Japan.

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http://dx.doi.org/10.1159/000361011DOI Listing
January 2015

Modulated electro-hyperthermia enhances dendritic cell therapy through an abscopal effect in mice.

Oncol Rep 2014 Dec 19;32(6):2373-9. Epub 2014 Sep 19.

Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.

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http://dx.doi.org/10.3892/or.2014.3500DOI Listing
December 2014

Genetic relatedness between Japanese and European isolates of Clostridium difficile originating from piglets and their risk associated with human health.

Front Microbiol 2014 8;5:513. Epub 2014 Oct 8.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University Hokkaido, Japan.

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http://dx.doi.org/10.3389/fmicb.2014.00513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189341PMC
October 2014

Aurora kinase A is a possible target of OSU‑03012 to destabilize MYC family proteins.

Oncol Rep 2014 Sep 11;32(3):901-5. Epub 2014 Jul 11.

Department of Anatomy and Cell Biology, College of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA.

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http://dx.doi.org/10.3892/or.2014.3325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121397PMC
September 2014

Isolation of Escherichia coli strains with AcrAB-TolC efflux pump-associated intermediate interpretation or resistance to fluoroquinolone, chloramphenicol and aminopenicillin from dogs admitted to a university veterinary hospital.

J Vet Med Sci 2014 Jul 18;76(7):937-45. Epub 2014 Mar 18.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunkyodai, Ebetsu 069-8501, Hokkaido, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143654PMC
http://dx.doi.org/10.1292/jvms.13-0144DOI Listing
July 2014

Genetic diversity in the prion protein gene (PRNP) of domestic cattle and water buffaloes in Vietnam, Indonesia and Thailand.

J Vet Med Sci 2014 Jul 7;76(7):1001-8. Epub 2014 Apr 7.

Laboratory of Zoonotic Diseases, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143640PMC
http://dx.doi.org/10.1292/jvms.13-0642DOI Listing
July 2014

Effects of fluoroquinolone treatment and group housing of pigs on the selection and spread of fluoroquinolone-resistant Campylobacter.

Vet Microbiol 2014 Jun 8;170(3-4):438-41. Epub 2014 Feb 8.

School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunkyodai, Ebetsu, Hokkaido, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.vetmic.2014.01.036DOI Listing
June 2014

Amino acid substitutions in GyrA and ParC are associated with fluoroquinolone resistance in Mycoplasma bovis isolates from Japanese dairy calves.

J Vet Med Sci 2013 15;75(8):1063-5. Epub 2013 Mar 15.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, 582 Bunkyoudai-Midorimachi, Ebetsu, Hokkaido 069-8501, Japan.

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http://dx.doi.org/10.1292/jvms.12-0508DOI Listing
April 2014

Non-deep-seated primary CNS lymphoma: therapeutic responses and a molecular signature.

J Neurooncol 2014 Apr 1;117(2):261-8. Epub 2014 Feb 1.

Department of Neurological Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba City, Chiba, 260-8670, Japan,

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http://dx.doi.org/10.1007/s11060-014-1379-4DOI Listing
April 2014

Comparison of broad-spectrum cephalosporin-resistant Escherichia coli isolated from dogs and humans in Hokkaido, Japan.

J Infect Chemother 2014 Apr 24;20(4):243-9. Epub 2014 Jan 24.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jiac.2013.12.003DOI Listing
April 2014

Methicillin-resistant Staphylococcus aureus carriage among veterinary staff and dogs in private veterinary clinics in Hokkaido, Japan.

Microbiol Immunol 2014 Mar;58(3):149-54

Department of Veterinary Medicine, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, 183-8509, Japan; School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido, 069-8501, Japan.

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http://dx.doi.org/10.1111/1348-0421.12128DOI Listing
March 2014

Phylogenetic association of fluoroquinolone and cephalosporin resistance of D-O1-ST648 Escherichia coli carrying blaCMY-2 from faecal samples of dogs in Japan.

J Med Microbiol 2014 Feb 21;63(Pt 2):263-270. Epub 2013 Feb 21.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan.

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http://dx.doi.org/10.1099/jmm.0.054676-0DOI Listing
February 2014

Identification of novel candidate compounds targeting TrkB to induce apoptosis in neuroblastoma.

Cancer Med 2014 Feb 1;3(1):25-35. Epub 2014 Jan 1.

Division of Biochemistry and Innovative Cancer Therapeutics, Chiba Cancer Center Research Institute, Chiba, 260-8717, Japan.

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http://dx.doi.org/10.1002/cam4.175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930387PMC
February 2014

Intra-subspecies sequence variability of the MACPPE12 gene in Mycobacterium avium subsp. hominissuis.

Infect Genet Evol 2014 Jan 20;21:479-83. Epub 2013 Sep 20.

Division of Global Epidemiology, Hokkaido University Research Center for Zoonosis Control, Kita-20, Nishi-10, Kita-ku, Sapporo 001-0020, Japan.

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http://dx.doi.org/10.1016/j.meegid.2013.08.010DOI Listing
January 2014

A new VGLUT-specific potent inhibitor: pharmacophore of Brilliant Yellow.

Neurochem Res 2014 Jan 19;39(1):117-28. Epub 2013 Nov 19.

Molecular and Behavioral Neuroscience Institute, Medical School, The University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA.

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http://dx.doi.org/10.1007/s11064-013-1196-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025951PMC
January 2014

Near-infrared-fluorescence imaging of lymph nodes by using liposomally formulated indocyanine green derivatives.

Bioorg Med Chem 2014 Jan 20;22(2):721-7. Epub 2013 Dec 20.

Center for Frontier Medical Engineering, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan; Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2013.12.026DOI Listing
January 2014

Prediction of the interaction between spermidine and the G-G mismatch containing acceptor stem in tRNA(Ile): molecular modeling, density functional theory, and molecular dynamics study.

Biochem Biophys Res Commun 2013 Nov 12;441(4):999-1004. Epub 2013 Nov 12.

Department of Organic and Polymeric Materials, Graduate School of Science and Engineering, Tokyo Institute of Technology, Tokyo 152-8522, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2013.11.016DOI Listing
November 2013

The role of flies in spreading the extended-spectrum β-lactamase gene from cattle.

Microb Drug Resist 2013 Oct 9;19(5):415-20. Epub 2013 May 9.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University , Ebetsu, Hokkaido, Japan .

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http://www.liebertpub.com/doi/10.1089/mdr.2012.0251
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http://dx.doi.org/10.1089/mdr.2012.0251DOI Listing
October 2013

Affinity maturation of a CDR3-grafted VHH using in silico analysis and surface plasmon resonance.

J Biochem 2013 Oct 31;154(4):325-32. Epub 2013 Jul 31.

Kyowa Hakko Kirin Co., Ltd., 3-6-6 Asahi-machi, Machida, Tokyo 194-8533; and Department of Bioinformatics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.

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http://dx.doi.org/10.1093/jb/mvt058DOI Listing
October 2013

Distribution of antimicrobial-resistant lactic acid bacteria in natural cheese in Japan.

Microbiol Immunol 2013 Oct;57(10):684-91

Department of Veterinary Medicine, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509; School of Veterinary Medicine.

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http://dx.doi.org/10.1111/1348-0421.12090DOI Listing
October 2013

Fluoroquinolone resistance mechanisms in an Escherichia coli isolate, HUE1, without quinolone resistance-determining region mutations.

Front Microbiol 2013 24;4:125. Epub 2013 May 24.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University Ebetsu, Japan.

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http://dx.doi.org/10.3389/fmicb.2013.00125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662882PMC
June 2013

Contribution of the AcrAB-TolC efflux pump to high-level fluoroquinolone resistance in Escherichia coli isolated from dogs and humans.

J Vet Med Sci 2013 May 14;75(4):407-14. Epub 2012 Nov 14.

Laboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunkyoudai, Ebetsu, Hokkaido, Japan.

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http://dx.doi.org/10.1292/jvms.12-0186DOI Listing
May 2013

An in vitro method for evaluating endotoxic activity using prostaglandin E(2) induction in bovine peripheral blood.

Biologicals 2013 May 9;41(3):158-61. Epub 2013 Mar 9.

National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, 1-15-1 Tokura, Kokubunji, Tokyo 185-8511, Japan.

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http://dx.doi.org/10.1016/j.biologicals.2013.02.001DOI Listing
May 2013

Presence of Staphylococcus aureus ST398 and ST9 in Swine in Japan.

Jpn J Infect Dis 2012 ;65(6):551-2

National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, Tokyo, Japan. asai-t@nval.maff.go.jp

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http://dx.doi.org/10.7883/yoken.65.551DOI Listing
April 2013

Effect of Antimicrobial Exposure on AcrAB Expression in Salmonella enterica Subspecies enterica Serovar Choleraesuis.

Front Microbiol 2013 14;4:53. Epub 2013 Mar 14.

National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries Kokubunji, Tokyo, Japan ; School of Veterinary Medicine, Rakuno Gakuen University Ebetsu, Hokkaido, Japan.

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http://dx.doi.org/10.3389/fmicb.2013.00053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596762PMC
March 2013