Publications



A novel thymoma-associated autoimmune disease: Anti-PIT-1 antibody syndrome.
Sci Rep 2017 Feb 20;7:43060. Epub 2017 Feb 20.
Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

Genetic and clinical characteristics of Japanese patients with sporadic somatotropinoma.
Endocr J 2016 Nov 6;63(11):953-963. Epub 2016 Aug 6.
Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

Evaluation of Functional Marrow Irradiation Based on Skeletal Marrow Composition Obtained Using Dual-Energy Computed Tomography.
Int J Radiat Oncol Biol Phys 2016 Nov 6;96(3):679-87. Epub 2016 Jul 6.
Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Department of Therapeutic Radiology, University of Minnesota, Minneapolis, Minnesota; Department of Radiation Oncology, Beckman Research Institute, City of Hope, Duarte, California. Electronic address:

Fast Megavoltage Computed Tomography: A Rapid Imaging Method for Total Body or Marrow Irradiation in Helical Tomotherapy.
Int J Radiat Oncol Biol Phys 2016 Nov 6;96(3):688-95. Epub 2016 Jul 6.
Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Department of Therapeutic Radiology, University of Minnesota, Minneapolis, Minnesota; Department of Radiation Oncology and Beckman Research Institute, City of Hope, Duarte, California. Electronic address:

The prognostic value of serum CA 19-9 for patients with advanced lung adenocarcinoma.
BMC Cancer 2016 Nov 14;16(1):890. Epub 2016 Nov 14.
Department of Respiratory Medicine, Kobe City Medical Center, General Hospital, 2-1-1 Minatojima-minamimachi, Chuo-ku, Kobe, 650-0047, Japan.


The influence of type 2 diabetes on serum GH and IGF-I levels in hospitalized Japanese patients.
Growth Horm IGF Res 2016 Aug 26;29:4-10. Epub 2016 Mar 26.
Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan. Electronic address:


A concept for classification of optimal breathing pattern for use in radiotherapy tracking, based on respiratory tumor kinematics and minimum jerk analysis.
Med Phys 2016 Jun;43(6):3168-3177
Department of Radiation Oncology, Osaka University Graduate School of Medicine, Yamadaoka 2-2, Suita-shi, Osaka 565-0871, Japan.




Correlation between patients' anatomical characteristics and interfractional internal prostate motion during intensity modulated radiation therapy for prostate cancer.
Springerplus 2015 6;4:579. Epub 2015 Oct 6.
Department of Radiation Oncology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 Japan.

A diagnostic pitfall in IgG4-related hypophysitis: infiltration of IgG4-positive cells in the pituitary of granulomatosis with polyangiitis.
Pituitary 2015 Oct;18(5):722-30
Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan.


Accelerated Telomere Shortening in Acromegaly; IGF-I Induces Telomere Shortening and Cellular Senescence.
PLoS One 2015 8;10(10):e0140189. Epub 2015 Oct 8.
Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.

Median-lower normal levels of serum thyroxine are associated with low triiodothyronine levels and body temperature in patients with central hypothyroidism.
Eur J Endocrinol 2015 Aug 20;173(2):247-56. Epub 2015 May 20.
Division of Diabetes and EndocrinologyKobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, JapanDivision of Diabetes and EndocrinologyKobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.

The prevalence and associated factors of colorectal neoplasms in acromegaly: a single center based study.
Pituitary 2015 Jun;18(3):343-51
Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan.

Radiation response of mesenchymal stem cells derived from bone marrow and human pluripotent stem cells.
J Radiat Res 2015 Mar 24;56(2):269-77. Epub 2014 Nov 24.
Masonic Cancer Center, University of Minnesota, 420 Delaware Street SE, Mayo Mail Code 494, Minneapolis, MN 55455, USA Department of Therapeutic Radiology, University of Minnesota, 420 Delaware Street SE, Mayo Mail Code 494, Minneapolis, MN 55455, USA


Long-term effects of growth hormone replacement therapy on liver function in adult patients with growth hormone deficiency.
Growth Horm IGF Res 2014 Oct 31;24(5):174-9. Epub 2014 Jul 31.
Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan. Electronic address:

Involvement of PIT-1-reactive cytotoxic T lymphocytes in anti-PIT-1 antibody syndrome.
J Clin Endocrinol Metab 2014 Sep 17;99(9):E1744-9. Epub 2014 Jun 17.
Division of Diabetes and Endocrinology, Department of Internal Medicine (H.B., G.I., H.F., M.Y., R.H., R.M., K.S., H.N., M.T., Y.T.), Kobe University Graduate School of Medicine, Kobe 650-0017, Japan; Department of Nutrition (Y.O.), Kobe Woman's University, Kobe 654-8585; Division of Diabetes and Endocrinology, Department of Medicine (K.T), Jikei University School of Medicine, 105-8461 Tokyo, Japan.


Diabetic osteopenia by decreased β-catenin signaling is partly induced by epigenetic derepression of sFRP-4 gene.
PLoS One 2014 18;9(7):e102797. Epub 2014 Jul 18.
Department of Pathology, Division of Diagnostic Molecular Pathology, Kobe University Graduate School of Medicine, Kobe City, Japan; Department of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime, Japan; Department of Diagnostic Pathology, Ehime University Hospital, Shitsukawa, Toon City, Ehime, Japan.


A missense single-nucleotide polymorphism in the sialic acid acetylesterase (SIAE) gene is associated with anti-PIT-1 antibody syndrome.
Endocr J 2014 20;61(6):641-4. Epub 2014 Apr 20.
Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

First report of KPC-2 Carbapenemase-producing Klebsiella pneumoniae in Japan.
Antimicrob Agents Chemother 2014 May 24;58(5):2961-3. Epub 2014 Feb 24.
Department of Microbiology and Immunology, Graduate School of Health Care Sciences, Tokyo Medical and Dental University, Tokyo, Japan.


The potential role of transient receptor potential type A1 as a mechanoreceptor in human periodontal ligament cells.
Eur J Oral Sci 2013 Dec 31;121(6):538-44. Epub 2013 Aug 31.
Department of Physiological Science and Molecular Biology, Fukuoka Dental College, Fukuoka, Japan; Department of Oral Rehabilitation, Fukuoka Dental College, Fukuoka, Japan.

Estimation of rectal dose using daily megavoltage cone-beam computed tomography and deformable image registration.
Int J Radiat Oncol Biol Phys 2013 Nov;87(3):602-8
Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan; Department of Radiology, Osaka University Hospital, Suita, Osaka, Japan. Electronic address:

SIRT1 regulates adaptive response of the growth hormone--insulin-like growth factor-I axis under fasting conditions in liver.
Proc Natl Acad Sci U S A 2013 Sep 26;110(37):14948-53. Epub 2013 Aug 26.
Division of Diabetes and Endocrinology and Division of Cellular and Molecular Medicine, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.

A PROP1-binding factor, AES cloned by yeast two-hybrid assay represses PROP1-induced Pit-1 gene expression.
Mol Cell Endocrinol 2013 Aug 1;376(1-2):93-8. Epub 2013 Jun 1.
Department of Biophysics, Kobe University Graduate School of Health Science, 7-10-2, Tomogaoka, Suma-ku, Kobe 654-0142, Japan.

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