Yusuke Nakamura

Yusuke Nakamura

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Yusuke Nakamura

Publications by authors named "Yusuke Nakamura"

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Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy.

Mol Oncol 2020 Aug 8;14(8):1719-1730. Epub 2020 Jun 8.

Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, Japan.

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http://dx.doi.org/10.1002/1878-0261.12727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400786PMC
August 2020

Correction: Importance of gastric cancer for the diagnosis and surveillance of Japanese Lynch syndrome patients.

J Hum Genet 2020 07;65(7):633

Division of Clinical Genome Research, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1038/s10038-020-0747-5DOI Listing
July 2020

Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2.

J Hum Genet 2020 Jul 6;65(7):569-575. Epub 2020 May 6.

Project for Immunogenomics, Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, 135-8550, Japan.

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http://dx.doi.org/10.1038/s10038-020-0771-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200206PMC
July 2020

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.

Nat Genet 2020 Jul 8;52(7):669-679. Epub 2020 Jun 8.

Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

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http://dx.doi.org/10.1038/s41588-020-0640-3DOI Listing
July 2020

Plasma or Serum: Which Is Preferable for Mutation Detection in Liquid Biopsy?

Clin Chem 2020 Jul;66(7):946-957

Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, Japan.

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http://dx.doi.org/10.1093/clinchem/hvaa103DOI Listing
July 2020

SARS-CoV-2 genomic variations associated with mortality rate of COVID-19.

J Hum Genet 2020 Jul 22. Epub 2020 Jul 22.

Project for Immunogenomics, Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, 135-8550, Japan.

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http://dx.doi.org/10.1038/s10038-020-0808-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375454PMC
July 2020

Imaging of lysophosphatidylcholine in an induced pluripotent stem cell-derived endothelial cell network.

Regen Ther 2020 Jun 18;14:299-305. Epub 2020 May 18.

Department of Biochemistry, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan.

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http://dx.doi.org/10.1016/j.reth.2020.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240204PMC
June 2020

A case of spindle cell dominant histiocytic sarcoma showing a complete remission after first-line chemotherapy with doxorubicin and ifosfamide.

J Chemother 2020 May 20:1-6. Epub 2020 May 20.

Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Tochigi, Japan.

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http://dx.doi.org/10.1080/1120009X.2020.1767477DOI Listing
May 2020

Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer.

Breast Cancer Res Treat 2020 Apr 4;180(2):331-341. Epub 2020 Feb 4.

Department of Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.

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http://dx.doi.org/10.1007/s10549-019-05512-5DOI Listing
April 2020

Induced Pluripotent Stem Cells for Regenerative Medicine: Quality Control Based on Evaluation of Lipid Composition.

Adv Exp Med Biol 2020 ;1212:49-56

Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, Japan.

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http://link.springer.com/10.1007/5584_2019_394
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http://dx.doi.org/10.1007/5584_2019_394DOI Listing
February 2020

Acute generalized exanthematous pustulosis induced by hydroxychloroquine successfully treated with etretinate.

J Dermatol 2020 Feb 15;47(2):e53-e54. Epub 2019 Dec 15.

Departments of, Department of, Dermatology, Faculty of Medicine, Oita University, Yufu, Japan.

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http://dx.doi.org/10.1111/1346-8138.15185DOI Listing
February 2020

The GALNT6‑LGALS3BP axis promotes breast cancer cell growth.

Int J Oncol 2020 Feb 13;56(2):581-595. Epub 2019 Dec 13.

Division of Genome Medicine, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Tokushima 770‑8503, Japan.

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http://dx.doi.org/10.3892/ijo.2019.4941DOI Listing
February 2020

CMOS-based bio-image sensor spatially resolves neural activity-dependent proton dynamics in the living brain.

Nat Commun 2020 02 5;11(1):712. Epub 2020 Feb 5.

Division of Homeostatic Development, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki, 444-8585, Japan.

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http://dx.doi.org/10.1038/s41467-020-14571-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002452PMC
February 2020

Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.

Cancer Med 2020 01 12;9(1):324-334. Epub 2019 Nov 12.

Department of Medicine, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1002/cam4.2695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943155PMC
January 2020

Importance of gastric cancer for the diagnosis and surveillance of Japanese Lynch syndrome patients.

J Hum Genet 2019 Dec 7;64(12):1187-1194. Epub 2019 Oct 7.

Division of Clinical Genome Research, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://www.nature.com/articles/s10038-019-0674-5
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http://dx.doi.org/10.1038/s10038-019-0674-5DOI Listing
December 2019

Recent transition of medical cost and relapse rate of multiple sclerosis in Japan based on analysis of a health insurance claims database.

BMC Neurol 2019 Dec 16;19(1):324. Epub 2019 Dec 16.

International University of Health and Welfare, School of Medicine, Center for Medical Education, 4-2 Kozunomori, Narita, Chiba, 286-8686, Japan.

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http://dx.doi.org/10.1186/s12883-019-1534-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912943PMC
December 2019

Tamoxifen Metabolism and Breast Cancer Recurrence: A Question Unanswered by CYPTAM.

J Clin Oncol 2019 08 18;37(22):1982-1983. Epub 2019 Jun 18.

Matthew P. Goetz, MD and Vera J. Suman, PhD, Mayo Clinic, Rochester, MN; Yusuke Nakamura, MD, PhD and Kazuma Kiyotani, PhD, Cancer Precision Medicine Center, Tokyo, Japan; V. Craig Jordan, PhD, DSc, The University of Texas MD Anderson Cancer Center, Houston, TX; and James N. Ingle, MD, Mayo Clinic, Rochester, MN.

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https://ascopubs.org/doi/10.1200/JCO.19.00504
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http://dx.doi.org/10.1200/JCO.19.00504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675592PMC
August 2019

The road map of cancer precision medicine with the innovation of advanced cancer detection technology and personalized immunotherapy.

Jpn J Clin Oncol 2019 Jul;49(7):596-603

Project for Immunogenomics, Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, Japan.

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http://dx.doi.org/10.1093/jjco/hyz073DOI Listing
July 2019

Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.

Clin Pharmacol Ther 2019 06 17;105(6):1477-1491. Epub 2019 Feb 17.

General Medicine and Hypertension Unit, Department of Medicine, University of Verona, Verona, Italy.

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http://doi.wiley.com/10.1002/cpt.1323
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http://dx.doi.org/10.1002/cpt.1323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542461PMC
June 2019

MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.

Oncol Rep 2019 Apr 30;41(4):2540-2548. Epub 2019 Jan 30.

Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.

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http://www.spandidos-publications.com/10.3892/or.2019.6988
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http://dx.doi.org/10.3892/or.2019.6988DOI Listing
April 2019

Tandem N, N-Dialkylation Reaction of N-Trimethylsilyl α-Iminoesters Utilizing an Umpolung Reaction and Characteristics of the Silyl Substituent: Synthesis of Pyrrolidine, Piperidine, and Iminodiacetate.

Org Lett 2019 04 8;21(8):2663-2667. Epub 2019 Apr 8.

Department of Chemistry for Materials , Graduate School of Engineering, Mie University , Tsu , Mie 514-8507 , Japan.

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http://dx.doi.org/10.1021/acs.orglett.9b00654DOI Listing
April 2019

Critical roles of protein methyltransferases and demethylases in the regulation of embryonic stem cell fate.

Epigenetics 2017 16;12(12):1015-1027. Epub 2018 Jan 16.

a Section of Hematology/Oncology, Department of Medicine , The University of Chicago , 5841 S. Maryland Ave, MC2115 Chicago , IL 60637 , USA.

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http://dx.doi.org/10.1080/15592294.2017.1391430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810763PMC
December 2018

Impact of support agreement between municipalities and convenience store chain companies on store staff's support activities for older adults.

Health Policy 2018 Dec 28;122(12):1377-1383. Epub 2018 Sep 28.

Department of Gerontological Home Care and Long-Term Care Nursing, Division of Health Sciences and Nursing, Graduate School of Medicine, The University of Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.healthpol.2018.09.015DOI Listing
December 2018

Immunotherapy with cancer peptides in combination with intravesical bacillus Calmette-Guerin for patients with non-muscle invasive bladder cancer.

Cancer Immunol Immunother 2018 Sep 3;67(9):1371-1380. Epub 2018 Jul 3.

Department of Urology, Iwate Medical University School of Medicine, 19-1 Uchimaru, Morioka, 020-8505, Japan.

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http://dx.doi.org/10.1007/s00262-018-2197-xDOI Listing
September 2018

Stimulation of the ATPase activity of Hsp90 by zerumbone modification of its cysteine residues destabilizes its clients and causes cytotoxicity.

Biochem J 2018 08 16;475(15):2559-2576. Epub 2018 Aug 16.

Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1042/BCJ20180230DOI Listing
August 2018

Free‑floating cancer cells in lymph node sinuses of hilar lymph node‑positive patients with non‑small cell lung cancer.

Mol Med Rep 2018 Jul 14;18(1):1081-1087. Epub 2018 May 14.

Division of Thoracic Surgery, Department of Surgery, Tokai University School of Medicine, Isehara‑shi, Kanagawa 259‑1193, Japan.

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http://dx.doi.org/10.3892/mmr.2018.9014DOI Listing
July 2018

The era of immunogenomics/immunopharmacogenomics.

J Hum Genet 2018 Jul 21;63(8):865-875. Epub 2018 May 21.

Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.

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http://dx.doi.org/10.1038/s10038-018-0468-1DOI Listing
July 2018

α-particle therapy for synovial sarcoma in the mouse using an astatine-211-labeled antibody against frizzled homolog 10.

Cancer Sci 2018 Jul 27;109(7):2302-2309. Epub 2018 Jun 27.

Radiation and Cancer Biology Team, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

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http://doi.wiley.com/10.1111/cas.13636
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http://dx.doi.org/10.1111/cas.13636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029834PMC
July 2018

Breast cancer: The translation of big genomic data to cancer precision medicine.

Cancer Sci 2018 Mar 30;109(3):497-506. Epub 2017 Dec 30.

Department of Medicine, Center for Personalized Therapeutics, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1111/cas.13463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834810PMC
March 2018

Immunopharmacogenomics towards personalized cancer immunotherapy targeting neoantigens.

Cancer Sci 2018 Mar 14;109(3):542-549. Epub 2018 Feb 14.

Department of Medicine, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1111/cas.13498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834780PMC
March 2018

Plasma and intracellular concentrations in an elderly patient with chronic myeloid leukemia receiving low-dose dasatinib therapy.

Geriatr Gerontol Int 2018 Mar;18(3):505-507

Department of Biopharmaceutical Sciences and Pharmacy, Laboratory of Pharmacokinetics, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.

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http://dx.doi.org/10.1111/ggi.13238DOI Listing
March 2018

Characterization of the B-cell receptor repertoires in peanut allergic subjects undergoing oral immunotherapy.

J Hum Genet 2018 Feb 30;63(2):239-248. Epub 2017 Nov 30.

Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.

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http://dx.doi.org/10.1038/s10038-017-0364-0DOI Listing
February 2018

Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility.

Cell Rep 2018 02;22(6):1473-1483

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan; Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo 108-8639, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.01.031DOI Listing
February 2018

Temporal Changes of Inflammatory Cytokine Profiles in Epithelial Lining Fluid in a Canine Lung Transplant Model.

Tokai J Exp Clin Med 2017 Dec 20;42(4):165-175. Epub 2017 Dec 20.

Division of General Thoracic Surgery, Department of Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.

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December 2017

Observation of water evaporation and stratum corneum hydration and pH during the clinical course of a patient with acquired idiopathic generalized anhidrosis.

J Dermatol 2017 Nov 5;44(11):e308-e309. Epub 2017 Jul 5.

Department of Dermatology, Faculty of Medicine, Oita University, Oita, Japan.

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http://dx.doi.org/10.1111/1346-8138.13954DOI Listing
November 2017

Video-assisted segmental resection of an intrapulmonary bronchogenic cyst mimicking a middle mediastinal cystic tumor.

Asian J Endosc Surg 2017 Nov 5;10(4):404-406. Epub 2017 Jul 5.

Division of Thoracic Surgery, Department of Surgery, Tokai University School of Medicine, Kanagawa, Japan.

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http://dx.doi.org/10.1111/ases.12396DOI Listing
November 2017

Residual ethylene glycol and dimethyl sulphoxide concentration in human ovarian tissue during warming/thawing steps following cryopreservation.

Reprod Biomed Online 2017 Sep 6;35(3):311-313. Epub 2017 Jun 6.

Kyono ART Clinic, 1-1 3F, Honcho, Aobaku, Sendai, Miyagi, 980-0014, Japan; Kyono ART Clinic Takanawa, Takanawa Court 5F, 3-13-1, Takanawa, Minatoku, Tokyo, 108-0074, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14726483173024
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http://dx.doi.org/10.1016/j.rbmo.2017.05.016DOI Listing
September 2017

Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers.

Oncotarget 2017 Sep 28;8(37):62029-62038. Epub 2017 Jun 28.

Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.18632/oncotarget.18790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617483PMC
September 2017

Toxic epidermal necrolysis in a child 6 months post-hematopoietic stem cell transplantation.

Pediatr Transplant 2017 Aug 12;21(5). Epub 2017 May 12.

Department of Pediatrics, Oita University Faculty of Medicine, Oita University, Oita, Japan.

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http://doi.wiley.com/10.1111/petr.12931
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http://dx.doi.org/10.1111/petr.12931DOI Listing
August 2017

Erratum to "Characteristics and prognosis of Japanese colorectal cancer patients: The BioBank Japan Project" [J Epidemiol 27(3S) (2017) S36-S42].

J Epidemiol 2017 08 5;27(8):398-399. Epub 2017 Jun 5.

Laboratory of Molecular Medicine, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, USA.

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http://dx.doi.org/10.1016/j.je.2017.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549245PMC
August 2017

p53-independent p21 induction by MELK inhibition.

Oncotarget 2017 Aug 15;8(35):57938-57947. Epub 2017 Jun 15.

Department of Medicine, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.18632/oncotarget.18488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601624PMC
August 2017

Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.

Cancer Med 2017 Jul 22;6(7):1665-1672. Epub 2017 Jun 22.

Section of Hematology/Oncology, Department of Medicine, The University of Chicago, 5841 S. Maryland Ave, MC2115, Chicago, Illinois, 60637.

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http://dx.doi.org/10.1002/cam4.1099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504314PMC
July 2017

The Transcriptional Landscape of p53 Signalling Pathway.

EBioMedicine 2017 Jun 18;20:109-119. Epub 2017 May 18.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan; Laboratory of Clinical Genome Sequence, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478243PMC
June 2017

A Pilot Study of Post-Operative Adjuvant Vaccine for Advanced Gastric Cancer.

Yonago Acta Med 2017 06 26;60(2):101-105. Epub 2017 Jun 26.

Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502221PMC
June 2017

Productivity and deadweight losses due to relapses of schizophrenia in Japan.

Neuropsychiatr Dis Treat 2017 17;13:1341-1348. Epub 2017 May 17.

Health Economics, Janssen Pharmaceutical K.K., Tokyo, Japan.

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http://dx.doi.org/10.2147/NDT.S138033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439971PMC
May 2017