Yuquan Wei

Yuquan Wei

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Yuquan Wei

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A novel method to purify adenovirus based on increasing salt concentrations in buffer.

Eur J Pharm Sci 2020 Jan 15;141:105090. Epub 2019 Oct 15.

State Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejps.2019.105090DOI Listing
January 2020

Roles of different humin and heavy-metal resistant bacteria from composting on heavy metal removal.

Bioresour Technol 2020 Jan 6;296:122375. Epub 2019 Nov 6.

College of Life Science, Northeast Agricultural University, Harbin 150030, China. Electronic address:

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http://dx.doi.org/10.1016/j.biortech.2019.122375DOI Listing
January 2020

Corrigendum to "Lobaplatin arrests cell cycle progression, induces apoptosis and impairs migration and invasion in B16-F10 melanoma cell line in vitro" [Biomed. Pharmacother. 69 (2015) 402-408].

Biomed Pharmacother 2019 Dec 16;120:109511. Epub 2019 Oct 16.

State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, China.

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http://dx.doi.org/10.1016/j.biopha.2019.109511DOI Listing
December 2019

JMJD3 in the regulation of human diseases.

Protein Cell 2019 Dec 7;10(12):864-882. Epub 2019 Nov 7.

Laboratory of Aging Research and Nanotoxicology, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, China.

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http://dx.doi.org/10.1007/s13238-019-0653-9DOI Listing
December 2019

Transcription-Related Dynamics from Immune Disability into Endogenous Innovation.

Adv Sci (Weinh) 2019 Dec 30;6(23):1900767. Epub 2019 Sep 30.

State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy West China Hospital Sichuan University Keyuan Road 4 No. 1, High Technological Development Zone Chengdu Sichuan 610041 P. R. China.

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http://dx.doi.org/10.1002/advs.201900767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891922PMC
December 2019

Effects of exogenous protein-like precursors on humification process during lignocellulose-like biomass composting: Amino acids as the key linker to promote humification process.

Bioresour Technol 2019 Nov 25;291:121882. Epub 2019 Jul 25.

College of Life Science, Northeast Agricultural University, Harbin 150030, China.

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http://dx.doi.org/10.1016/j.biortech.2019.121882DOI Listing
November 2019

Structural and functional studies of TBC1D23 C-terminal domain provide a link between endosomal trafficking and PCH.

Proc Natl Acad Sci U S A 2019 Nov 17;116(45):22598-22608. Epub 2019 Oct 17.

Key Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Paediatrics, West China Second University Hospital, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China;

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http://dx.doi.org/10.1073/pnas.1909316116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842616PMC
November 2019

AXL receptor tyrosine kinase as a promising anti-cancer approach: functions, molecular mechanisms and clinical applications.

Mol Cancer 2019 11 4;18(1):153. Epub 2019 Nov 4.

Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No. 17, Block 3, Southern Renmin Road, Chengdu, Sichuan, 610041, People's Republic of China.

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http://dx.doi.org/10.1186/s12943-019-1090-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827209PMC
November 2019

A new and promising application of gene editing: CRISPR-controlled smart materials for tissue engineering, bioelectronics, and diagnostics.

Sci China Life Sci 2019 Nov 1;62(11):1547-1549. Epub 2019 Nov 1.

Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, China.

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http://dx.doi.org/10.1007/s11427-019-1576-0DOI Listing
November 2019

Immunoregulatory Functions of Nuclear Receptors: Mechanisms and Therapeutic Implications.

Trends Endocrinol Metab 2019 Nov 6. Epub 2019 Nov 6.

Department of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE and State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2019.10.002DOI Listing
November 2019

The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression.

Cell Death Differ 2019 Oct 15;26(10):1929-1941. Epub 2019 Jan 15.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, 610041, China.

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http://dx.doi.org/10.1038/s41418-018-0262-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748082PMC
October 2019

Macrophage Foam Cell-Targeting Immunization Attenuates Atherosclerosis.

Front Immunol 2018 10;9:3127. Epub 2019 Jan 10.

State Key Laboratory of Biotherapy, Department of Anesthesiology and Translational Neuroscience Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Sichuan University, Chengdu, China.

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http://dx.doi.org/10.3389/fimmu.2018.03127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335275PMC
October 2019

Reducing ammonia and greenhouse gas emission with adding high levels of superphosphate fertilizer during composting.

Environ Sci Pollut Res Int 2019 Oct 24;26(30):30921-30929. Epub 2019 Aug 24.

Environmental Monitoring Station of Baotou, Baotou, 014060, Inner Mongolia, China.

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http://dx.doi.org/10.1007/s11356-019-06209-4DOI Listing
October 2019

Epigenetic regulation of macrophages: from homeostasis maintenance to host defense.

Cell Mol Immunol 2019 Oct 29. Epub 2019 Oct 29.

Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No. 17, Block 3, Southern Renmin Road, 610041, Chengdu, Sichuan, PR China.

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http://dx.doi.org/10.1038/s41423-019-0315-0DOI Listing
October 2019

SARI attenuates colon inflammation by promoting STAT1 degradation in intestinal epithelial cells.

Mucosal Immunol 2019 09 10;12(5):1130-1140. Epub 2019 Jun 10.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan Province, China.

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http://dx.doi.org/10.1038/s41385-019-0178-9DOI Listing
September 2019

Surgical stress and cancer progression: the twisted tango.

Mol Cancer 2019 09 2;18(1):132. Epub 2019 Sep 2.

Department of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE and State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University and Collaborative Innovation Center, 610041, Chengdu, Sichuan, People's Republic of China.

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http://dx.doi.org/10.1186/s12943-019-1058-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717988PMC
September 2019

Powerful anti-colon cancer effect of modified nanoparticle-mediated IL-15 immunogene therapy through activation of the host immune system.

Theranostics 2018 6;8(13):3490-3503. Epub 2018 Jun 6.

Department of Neurosurgery and Institute of Neurosurgery, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University/Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.

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http://dx.doi.org/10.7150/thno.24157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037032PMC
August 2019

Erratum: Powerful anti-colon cancer effect of modified nanoparticle-mediated IL-15 immunogene therapy through activation of the host immune system: Erratum.

Theranostics 2019;9(22):6466-6467. Epub 2019 Aug 17.

Department of Neurosurgery and Institute of Neurosurgery, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University/Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.

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http://dx.doi.org/10.7150/thno.39082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771235PMC
August 2019

Metabolism-induced tumor activator 1 (MITA1), an Energy Stress-Inducible Long Noncoding RNA, Promotes Hepatocellular Carcinoma Metastasis.

Hepatology 2019 Jul 26;70(1):215-230. Epub 2019 Apr 26.

Division of Endocrinology and Metabolism, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.

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http://doi.wiley.com/10.1002/hep.30602
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http://dx.doi.org/10.1002/hep.30602DOI Listing
July 2019

CRISPR-Cas9 Delivery by Artificial Virus (RRPHC).

Methods Mol Biol 2019 ;1961:81-91

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.

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http://dx.doi.org/10.1007/978-1-4939-9170-9_6DOI Listing
July 2019

Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.

Nat Commun 2019 07 19;10(1):3214. Epub 2019 Jul 19.

Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, 610064, Chengdu, China.

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http://dx.doi.org/10.1038/s41467-019-11154-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642264PMC
July 2019

Erratum: Negative regulation of cationic nanoparticle-induced inflammatory toxicity through the increased production of prostaglandin E2 via mitochondrial DNA-activated Ly6C monocytes: Erratum.

Theranostics 2019;9(19):5443. Epub 2019 Jul 17.

Lab of Aging Research and Nanotoxicology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, No. 17, Block 3, Southern Renmin Road, Chengdu, Sichuan 610041, PR China.

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http://dx.doi.org/10.7150/thno.37524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735400PMC
July 2019

Temporal expression and functional analysis of long non-coding RNAs in colorectal cancer initiation.

J Cell Mol Med 2019 Jun 28;23(6):4127-4138. Epub 2019 Mar 28.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, P. R. China.

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http://dx.doi.org/10.1111/jcmm.14300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533480PMC
June 2019

Bat adeno-associated viruses as gene therapy vectors with the potential to evade human neutralizing antibodies.

Gene Ther 2019 06 20;26(6):264-276. Epub 2019 May 20.

Department of Cardiology and Laboratory of Gene Therapy for Heart Diseases, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan, China.

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http://dx.doi.org/10.1038/s41434-019-0081-8DOI Listing
June 2019

Negative regulation of cationic nanoparticle-induced inflammatory toxicity through the increased production of prostaglandin E2 via mitochondrial DNA-activated Ly6C monocytes.

Theranostics 2018 6;8(11):3138-3152. Epub 2018 May 6.

Lab of Aging Research and Nanotoxicology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, No. 17, Block 3, Southern Renmin Road, Chengdu, Sichuan 610041, PR China.

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http://dx.doi.org/10.7150/thno.21693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996362PMC
May 2019

Targeting Metabolic-Redox Circuits for Cancer Therapy.

Trends Biochem Sci 2019 05 21;44(5):401-414. Epub 2019 Jan 21.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital and West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.tibs.2019.01.001DOI Listing
May 2019

The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation.

Mol Metab 2019 05 20;23:14-23. Epub 2019 Feb 20.

Division of Endocrinology and Metabolism, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu 610041, Sichuan, China. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480316PMC
May 2019

Induction of neutrophil extracellular traps during tissue injury: Involvement of STING and Toll-like receptor 9 pathways.

Cell Prolif 2019 May 9;52(3):e12579. Epub 2019 Mar 9.

Lab of Aging Research and Nanotoxicology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan, China.

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http://dx.doi.org/10.1111/cpr.12579DOI Listing
May 2019

Rapid 3D printing of functional nanoparticle-enhanced conduits for effective nerve repair.

Acta Biomater 2019 May 28;90:49-59. Epub 2019 Mar 28.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan 610065, China.

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http://dx.doi.org/10.1016/j.actbio.2019.03.047DOI Listing
May 2019

Immune checkpoint blockade and its combination therapy with small-molecule inhibitors for cancer treatment.

Biochim Biophys Acta Rev Cancer 2019 04 31;1871(2):199-224. Epub 2018 Dec 31.

Laboratory of Aging Research and Nanotoxicology, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No. 17, Block 3, Southern Renmin Road, Chengdu, Sichuan 610041, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0304419X183020
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http://dx.doi.org/10.1016/j.bbcan.2018.12.002DOI Listing
April 2019

A novel role for ketoconazole in hepatocellular carcinoma treatment: linking PTGS2 to mitophagy machinery.

Autophagy 2019 04 22;15(4):733-734. Epub 2019 Jan 22.

b Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and West China School of Basic Medical Sciences & Forensic Medicine , Sichuan University, and Collaborative Innovation Center for Biotherapy , Chengdu , P.R. China.

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https://www.tandfonline.com/doi/full/10.1080/15548627.2019.1
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http://dx.doi.org/10.1080/15548627.2019.1569934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526862PMC
April 2019

Onsite quantifying electron donating capacity of dissolved organic matter.

Sci Total Environ 2019 Apr 19;662:57-64. Epub 2019 Jan 19.

School of Environment and State Key Joint Laboratory of Environment Simulation and Pollution Control, Tsinghua University, Beijing 100084, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00489697193019
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http://dx.doi.org/10.1016/j.scitotenv.2019.01.178DOI Listing
April 2019

Targeted demethylation of the SARI promotor impairs colon tumour growth.

Cancer Lett 2019 Apr 14;448:132-143. Epub 2019 Feb 14.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan, 610041, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2019.01.040DOI Listing
April 2019

Impact of phosphate additive on organic carbon component degradation during pig manure composting.

Environ Sci Pollut Res Int 2019 Apr 27;26(12):11805-11814. Epub 2019 Feb 27.

Environmental Monitoring Station of Baotou, Inner Mongolia, 014060, China.

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http://dx.doi.org/10.1007/s11356-019-04511-9DOI Listing
April 2019

3D Printing Enabled Customization of Functional Microgels.

ACS Appl Mater Interfaces 2019 Apr 25;11(13):12209-12215. Epub 2019 Mar 25.

Scientific Research Center , The Seventh Affiliated Hospital of Sun Yat-sen University , Shenzhen 518107 , Guangdong , P. R. China.

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http://pubs.acs.org/doi/10.1021/acsami.8b18701
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http://dx.doi.org/10.1021/acsami.8b18701DOI Listing
April 2019

Cellular Toxicity and Immunological Effects of Carbon-based Nanomaterials.

Part Fibre Toxicol 2019 04 11;16(1):18. Epub 2019 Apr 11.

Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No. 17, Block 3, Southern Renmin Road, Chengdu, Sichuan, 610041, People's Republic of China.

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http://dx.doi.org/10.1186/s12989-019-0299-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460856PMC
April 2019

Targeting mutant TP53 as a potential therapeutic strategy for the treatment of osteosarcoma.

J Orthop Res 2019 03 12;37(3):789-798. Epub 2019 Feb 12.

Sarcoma Biology Laboratory, Department of Orthopaedic Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, 90095.

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http://doi.wiley.com/10.1002/jor.24227
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http://dx.doi.org/10.1002/jor.24227DOI Listing
March 2019

Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma.

Autophagy 2019 Mar 25:1-17. Epub 2019 Mar 25.

a State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and West China School of Basic Medical Sciences & Forensic Medicine , Sichuan University, and Collaborative Innovation Center for Biotherapy , Chengdu , P.R. China.

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http://dx.doi.org/10.1080/15548627.2019.1598752DOI Listing
March 2019

Repositioning antipsychotic fluphenazine hydrochloride for treating triple negative breast cancer with brain metastases and lung metastases.

Am J Cancer Res 2019 1;9(3):459-478. Epub 2019 Mar 1.

Department of Rehabilitation Medicine, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy Chengdu 610041, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448056PMC
March 2019

Hyaluronic Acid Oligosaccharides Improve Myocardial Function Reconstruction and Angiogenesis against Myocardial Infarction by Regulation of Macrophages.

Theranostics 2019 16;9(7):1980-1992. Epub 2019 Mar 16.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China.

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http://www.thno.org/v09p1980.htm
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http://dx.doi.org/10.7150/thno.31073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485288PMC
March 2019

Identification of ANXA2 (annexin A2) as a specific bleomycin target to induce pulmonary fibrosis by impeding TFEB-mediated autophagic flux.

Autophagy 2018 29;14(2):269-282. Epub 2018 Jan 29.

d State Key Laboratory of Biotherapy and Cancer Center , West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy , Chengdu , China.

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http://dx.doi.org/10.1080/15548627.2017.1409405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902212PMC
February 2019

ZNF32 induces anoikis resistance through maintaining redox homeostasis and activating Src/FAK signaling in hepatocellular carcinoma.

Cancer Lett 2019 02 12;442:271-278. Epub 2018 Nov 12.

Lab of Cancer Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.

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https://linkinghub.elsevier.com/retrieve/pii/S03043835183066
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http://dx.doi.org/10.1016/j.canlet.2018.09.033DOI Listing
February 2019

Structural and mechanistic insights into polymyxin resistance mediated by EptC originating from Escherichia coli.

FEBS J 2019 02 22;286(4):750-764. Epub 2018 Dec 22.

Division of Respiratory and Critical Care Medicine, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.

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http://dx.doi.org/10.1111/febs.14719DOI Listing
February 2019

How do fungal communities and their interaction with bacterial communities influence dissolved organic matter on the stability and safety of sludge compost?

Environ Sci Pollut Res Int 2019 Feb 3;26(4):4141-4146. Epub 2019 Jan 3.

State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing, 100012, China.

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http://dx.doi.org/10.1007/s11356-018-4023-6DOI Listing
February 2019

Tumor cells induce LAMP2a expression in tumor-associated macrophage for cancer progression.

EBioMedicine 2019 Feb 30;40:118-134. Epub 2019 Jan 30.

State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.01.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413476PMC
February 2019

Targeting PI3K in cancer: mechanisms and advances in clinical trials.

Mol Cancer 2019 02 19;18(1):26. Epub 2019 Feb 19.

Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.

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http://dx.doi.org/10.1186/s12943-019-0954-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379961PMC
February 2019

Powerful Anticolon Tumor Effect of Targeted Gene Immunotherapy Using Folate-Modified Nanoparticle Delivery of CCL19 To Activate the Immune System.

ACS Cent Sci 2019 Feb 28;5(2):277-289. Epub 2019 Jan 28.

Department of Neurosurgery and Institute of Neurosurgery, State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041, PR China.

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http://dx.doi.org/10.1021/acscentsci.8b00688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396391PMC
February 2019

Effect of different components of single superphosphate on organic matter degradation and maturity during pig manure composting.

Sci Total Environ 2019 Jan 25;646:587-594. Epub 2018 Jul 25.

Environmental Monitoring Station of Baotou, Inner Mongolia 014060, China.

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http://dx.doi.org/10.1016/j.scitotenv.2018.07.336DOI Listing
January 2019

Improved lignocellulose-degrading performance during straw composting from diverse sources with actinomycetes inoculation by regulating the key enzyme activities.

Bioresour Technol 2019 Jan 17;271:66-74. Epub 2018 Sep 17.

College of Life Science, Northeast Agricultural University, Harbin 150030, China. Electronic address:

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http://dx.doi.org/10.1016/j.biortech.2018.09.081DOI Listing
January 2019

Ketoconazole exacerbates mitophagy to induce apoptosis by downregulating cyclooxygenase-2 in hepatocellular carcinoma.

J Hepatol 2019 01 1;70(1):66-77. Epub 2018 Oct 1.

Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu 610041, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01688278183244
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http://dx.doi.org/10.1016/j.jhep.2018.09.022DOI Listing
January 2019

Modulating the Tumor Microenvironment via Oncolytic Viruses and CSF-1R Inhibition Synergistically Enhances Anti-PD-1 Immunotherapy.

Mol Ther 2019 01 17;27(1):244-260. Epub 2018 Nov 17.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan 610041, China. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319306PMC
January 2019

Prediction of mortality in Chinese very old people through the frailty index based on routine laboratory data.

Sci Rep 2019 Jan 18;9(1):221. Epub 2019 Jan 18.

Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.

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http://dx.doi.org/10.1038/s41598-018-36569-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338748PMC
January 2019

Glutaminase 1 expression in colorectal cancer cells is induced by hypoxia and required for tumor growth, invasion, and metastatic colonization.

Cell Death Dis 2019 01 17;10(2):40. Epub 2019 Jan 17.

Department of Oncology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.

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http://www.nature.com/articles/s41419-018-1291-5
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http://dx.doi.org/10.1038/s41419-018-1291-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426853PMC
January 2019

An Endogenous Vaccine Based on Fluorophores and Multivalent Immunoadjuvants Regulates Tumor Micro-Environment for Synergistic Photothermal and Immunotherapy.

Theranostics 2018 1;8(3):860-873. Epub 2018 Jan 1.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, P. R. China.

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http://dx.doi.org/10.7150/thno.19826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771099PMC
December 2018

Pan-HER-targeted approach for cancer therapy: Mechanisms, recent advances and clinical prospect.

Cancer Lett 2018 12 12;439:113-130. Epub 2018 Sep 12.

Lab of Aging Research and Nanotoxicology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, No. 17, Block 3, Southern Renmin Road, Chengdu, Sichuan, 610041, PR China.

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https://linkinghub.elsevier.com/retrieve/pii/S03043835183047
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http://dx.doi.org/10.1016/j.canlet.2018.07.014DOI Listing
December 2018

Follistatin-like protein 5 inhibits hepatocellular carcinoma progression by inducing caspase-dependent apoptosis and regulating Bcl-2 family proteins.

J Cell Mol Med 2018 12 25;22(12):6190-6201. Epub 2018 Sep 25.

State Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

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http://dx.doi.org/10.1111/jcmm.13906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237577PMC
December 2018

Conversion of human adipose-derived stem cells into functional and expandable endothelial-like cells for cell-based therapies.

Stem Cell Res Ther 2018 12 17;9(1):350. Epub 2018 Dec 17.

State Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Ke-yuan Road 4, No. 1, Gao-peng Street, Chengdu, 610041, Sichuan, People's Republic of China.

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https://stemcellres.biomedcentral.com/articles/10.1186/s1328
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http://dx.doi.org/10.1186/s13287-018-1088-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296081PMC
December 2018

Roles of bacterial community in the transformation of dissolved organic matter for the stability and safety of material during sludge composting.

Bioresour Technol 2018 Nov 20;267:378-385. Epub 2018 Jul 20.

State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China. Electronic address:

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http://dx.doi.org/10.1016/j.biortech.2018.07.060DOI Listing
November 2018

Structural and functional insights into the regulation of the lysis-lysogeny decision in viral communities.

Nat Microbiol 2018 11 15;3(11):1285-1294. Epub 2018 Oct 15.

Division of Respiratory and Critical Care Medicine, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.

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http://dx.doi.org/10.1038/s41564-018-0259-7DOI Listing
November 2018

Zinc finger protein 32 promotes breast cancer stem cell-like properties through directly promoting GPER transcription.

Cell Death Dis 2018 11 26;9(12):1162. Epub 2018 Nov 26.

Division of Cancer Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.

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http://dx.doi.org/10.1038/s41419-018-1144-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255875PMC
November 2018

Enhanced degradation of ibuprofen by heterogeneous electro-Fenton at circumneutral pH.

Chemosphere 2018 Oct 28;209:998-1006. Epub 2018 Jun 28.

School of Environment and State Key Joint Laboratory of Environment Simulation and Pollution Control, Tsinghua University, Beijing 100084, China. Electronic address:

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http://dx.doi.org/10.1016/j.chemosphere.2018.06.164DOI Listing
October 2018

Three-Dimensional Ameliorated Biologics Elicit Thymic Renewal in Tumor-Bearing Hosts.

J Immunol 2018 10 27;201(7):1975-1983. Epub 2018 Aug 27.

State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, People's Republic of China;

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http://dx.doi.org/10.4049/jimmunol.1701727DOI Listing
October 2018

Delivery siRNA with a novel gene vector for glioma therapy by targeting Gli1.

Int J Nanomedicine 2018 27;13:4781-4793. Epub 2018 Aug 27.

Department of Pathology, Clinical Medicine College, Chengdu University of Traditional Chinese Medicine, Chengdu, People's Republic of China.

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https://www.dovepress.com/delivery-sirna-with-a-novel-gene-v
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http://dx.doi.org/10.2147/IJN.S164364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118331PMC
October 2018

Nuclear lactate dehydrogenase A senses ROS to produce α-hydroxybutyrate for HPV-induced cervical tumor growth.

Nat Commun 2018 10 24;9(1):4429. Epub 2018 Oct 24.

Fudan University Shanghai Cancer Center and Cancer Metabolism Laboratory, Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, P.R. China.

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http://www.nature.com/articles/s41467-018-06841-7
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http://dx.doi.org/10.1038/s41467-018-06841-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200739PMC
October 2018

Frailty and Cognitive Impairment in Predicting Mortality Among Oldest-Old People.

Front Aging Neurosci 2018 18;10:295. Epub 2018 Oct 18.

Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.

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https://www.frontiersin.org/article/10.3389/fnagi.2018.00295
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http://dx.doi.org/10.3389/fnagi.2018.00295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201058PMC
October 2018

Periclitoral accessory breast tissue in a lactating woman: A case report.

Medicine (Baltimore) 2018 Oct;97(43):e12936

Department of Neurosurgery, Department of Burns and Plastic Surgery, West China Hospital, State Key Laboratory of Biotherapy, Sichuan University, Sichuan, China.

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http://dx.doi.org/10.1097/MD.0000000000012936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221748PMC
October 2018

Systemic immune-inflammation index, SII, for prognosis of elderly patients with newly diagnosed tumors.

Oncotarget 2018 Oct 19;9(82):35293-35299. Epub 2018 Oct 19.

Department of Operation Management, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610072, P.R. China.

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http://www.oncotarget.com/fulltext/24293
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http://dx.doi.org/10.18632/oncotarget.24293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219675PMC
October 2018

Organophosphorus-degrading bacterial community during composting from different sources and their roles in phosphorus transformation.

Bioresour Technol 2018 Sep 26;264:277-284. Epub 2018 May 26.

College of Life Science, Northeast Agricultural University, Harbin 150030, China. Electronic address:

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http://dx.doi.org/10.1016/j.biortech.2018.05.088DOI Listing
September 2018

SKLB060 Reversibly Binds to Colchicine Site of Tubulin and Possesses Efficacy in Multidrug-Resistant Cell Lines.

Cell Physiol Biochem 2018 22;47(2):489-504. Epub 2018 May 22.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.

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http://dx.doi.org/10.1159/000489983DOI Listing
July 2018

Epigenetics in ovarian cancer: premise, properties, and perspectives.

Mol Cancer 2018 07 31;17(1):109. Epub 2018 Jul 31.

Department of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE and State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, 610041, People's Republic of China.

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http://dx.doi.org/10.1186/s12943-018-0855-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069741PMC
July 2018

Structural and Mechanistic Analyses Reveal a Unique Cas4-like Protein in the Mimivirus Virophage Resistance Element System.

iScience 2018 May 11;3:1-10. Epub 2018 Apr 11.

Division of Respiratory and Critical Care Medicine, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University and Collaborative Innovation Center of Biotherapy, 17th, 3rd Section, Southern Renmin Road, Chengdu, 610041, China. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2018.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137704PMC
May 2018

Biostimulation of nutrient additions on indigenous microbial community at the stage of nitrogen limitations during composting.

Waste Manag 2018 Apr 11;74:194-202. Epub 2017 Dec 11.

College of Life Science, Northeast Agricultural University, Harbin 150030, China. Electronic address:

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http://dx.doi.org/10.1016/j.wasman.2017.12.004DOI Listing
April 2018

Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis.

Proc Natl Acad Sci U S A 2018 04 28;115(16):E3673-E3681. Epub 2018 Mar 28.

Department of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of Ministry of Education and State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University and Collaborative Innovation Center, 610041 Chengdu, People's Republic of China;

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http://dx.doi.org/10.1073/pnas.1803291115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910874PMC
April 2018

SKLB-23bb, A HDAC6-Selective Inhibitor, Exhibits Superior and Broad-Spectrum Antitumor Activity via Additionally Targeting Microtubules.

Mol Cancer Ther 2018 04;17(4):763-775

State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu, China.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-0332DOI Listing
April 2018

G-395A polymorphism in the promoter region of the KLOTHO gene associates with frailty among the oldest-old.

Sci Rep 2018 04 30;8(1):6735. Epub 2018 Apr 30.

State Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

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http://dx.doi.org/10.1038/s41598-018-25040-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928057PMC
April 2018

The RNA binding protein SORBS2 suppresses metastatic colonization of ovarian cancer by stabilizing tumor-suppressive immunomodulatory transcripts.

Genome Biol 2018 03 16;19(1):35. Epub 2018 Mar 16.

Department of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE and State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, 610041, People's Republic of China.

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http://dx.doi.org/10.1186/s13059-018-1412-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857099PMC
March 2018

Molecular basis of binding between the global post-transcriptional regulator CsrA and the T3SS chaperone CesT.

Nat Commun 2018 03 22;9(1):1196. Epub 2018 Mar 22.

West China Hospital Emergency Department (WCHED), State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan, 610041, China.

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http://www.nature.com/articles/s41467-018-03625-x
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http://dx.doi.org/10.1038/s41467-018-03625-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864733PMC
March 2018

IL-35 recombinant protein reverses inflammatory bowel disease and psoriasis through regulation of inflammatory cytokines and immune cells.

J Cell Mol Med 2018 02 29;22(2):1014-1025. Epub 2017 Nov 29.

State Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.

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http://doi.wiley.com/10.1111/jcmm.13428
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http://dx.doi.org/10.1111/jcmm.13428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783847PMC
February 2018

Current Status of Nonviral Vectors for Gene Therapy in China.

Hum Gene Ther 2018 02;29(2):110-120

Laboratory for Aging Research and Nanotoxicology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University , and Collaborative Innovation Center for Biotherapy, Chengdu, P.R. China .

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http://www.liebertpub.com/doi/10.1089/hum.2017.226
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http://dx.doi.org/10.1089/hum.2017.226DOI Listing
February 2018

Mechanism of inhibition of retromer transport by the bacterial effector RidL.

Proc Natl Acad Sci U S A 2018 02 31;115(7):E1446-E1454. Epub 2018 Jan 31.

Key Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Pediatrics, Division of Neurology, West China Second University Hospital, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041 Chengdu, China;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1717383115
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http://dx.doi.org/10.1073/pnas.1717383115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816186PMC
February 2018

Recent Advances in Therapeutic Genome Editing in China.

Hum Gene Ther 2018 02;29(2):136-145

1 State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center , Chengdu, China.

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http://dx.doi.org/10.1089/hum.2017.210DOI Listing
February 2018

Apatinib alone or combined with radiotherapy in metastatic prostate cancer: Results from a pilot, multicenter study.

Oncotarget 2017 Dec 28;8(67):110774-110784. Epub 2017 Nov 28.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan, PR China.

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http://dx.doi.org/10.18632/oncotarget.22719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762283PMC
December 2017

Structural and mechanistic insights into the biosynthesis of CDP-archaeol in membranes.

Cell Res 2017 Nov 29;27(11):1378-1391. Epub 2017 Sep 29.

Division of Respiratory and Critical Care Medicine, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan 610041, China.

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http://dx.doi.org/10.1038/cr.2017.122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674157PMC
November 2017

Fabrication of Semiconductor ZnO Nanostructures for Versatile SERS Application.

Nanomaterials (Basel) 2017 Nov 19;7(11). Epub 2017 Nov 19.

Ceramics and Biomaterials Research Group, Ton Duc Thang University, Ho Chi Minh City 800010, Vietnam.

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http://dx.doi.org/10.3390/nano7110398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707615PMC
November 2017

Application of luteolin nanomicelles anti-glioma effect with improvement and .

Oncotarget 2017 Sep 19;8(37):61146-61162. Epub 2017 May 19.

Department of Neurosurgery and Institute of Neurosurgery, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, PR China.

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http://dx.doi.org/10.18632/oncotarget.18019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617413PMC
September 2017

Enhanced antitumor effect of biodegradable cationic heparin-polyethyleneimine nanogels delivering FILIP1LΔC103 gene combined with low-dose cisplatin on ovarian cancer.

Oncotarget 2017 Sep 22;8(44):76432-76442. Epub 2017 Jul 22.

Department of Gynecology and Obstetrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children of The Ministry of Education, West China Second Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.

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http://dx.doi.org/10.18632/oncotarget.19464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652717PMC
September 2017

A novel cancer vaccine with the ability to simultaneously produce anti-PD-1 antibody and GM-CSF in cancer cells and enhance Th1-biased antitumor immunity.

Signal Transduct Target Ther 2016 18;1:16025. Epub 2016 Nov 18.

State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

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http://www.nature.com/articles/sigtrans201625
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http://dx.doi.org/10.1038/sigtrans.2016.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661645PMC
November 2016