Yupu Deng

Yupu Deng

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Yupu Deng

Yupu Deng

Publications by authors named "Yupu Deng"

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Optimizing imaging of the rat pulmonary microvasculature by micro-computed tomography.

Pulm Circ 2019 Oct-Dec;9(4):2045894019883613. Epub 2019 Oct 31.

Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada.

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http://dx.doi.org/10.1177/2045894019883613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823983PMC
October 2019

High circulating angiopoietin-2 levels exacerbate pulmonary inflammation but not vascular leak or mortality in endotoxin-induced lung injury in mice.

Thorax 2018 03 25;73(3):248-261. Epub 2017 Sep 25.

Regenerative Medicine Program, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1136/thoraxjnl-2017-210413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870448PMC
March 2018

Effects of an endothelin receptor antagonist, Macitentan, on right ventricular substrate utilization and function in a Sugen 5416/hypoxia rat model of severe pulmonary arterial hypertension.

J Nucl Cardiol 2017 12 29;24(6):1979-1989. Epub 2016 Sep 29.

Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, 40 Ruskin St., Ottawa, ON, K1Y 4W7, Canada.

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http://dx.doi.org/10.1007/s12350-016-0663-4DOI Listing
December 2017

Systemic delivery of MicroRNA mimics with polyethylenimine elevates pulmonary microRNA levels, but lacks pulmonary selectivity.

Pulm Circ 2018 Jan-Mar;8(1):2045893217750613. Epub 2017 Dec 18.

1 10055 Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.

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http://dx.doi.org/10.1177/2045893217750613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753929PMC
December 2017

Cardiotrophin 1 stimulates beneficial myogenic and vascular remodeling of the heart.

Cell Res 2017 Oct 8;27(10):1195-1215. Epub 2017 Aug 8.

Sprott Centre for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa Hospital, Ottawa, Ontario K1H 8L6, Canada.

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http://dx.doi.org/10.1038/cr.2017.87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630684PMC
October 2017

Marked Strain-Specific Differences in the SU5416 Rat Model of Severe Pulmonary Arterial Hypertension.

Am J Respir Cell Mol Biol 2016 Apr;54(4):461-8

1 Sinclair Centre for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada; and.

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http://dx.doi.org/10.1165/rcmb.2014-0488OCDOI Listing
April 2016

Occlusive lung arterial lesions in endothelial-targeted, fas-induced apoptosis transgenic mice.

Am J Respir Cell Mol Biol 2015 Nov;53(5):712-8

1 Sinclair Centre for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1165/rcmb.2014-0311OCDOI Listing
November 2015

Discordant Regulation of microRNA Between Multiple Experimental Models and Human Pulmonary Hypertension.

Chest 2015 Aug;148(2):481-490

From the Regenerative Medicine Program, Ottawa Hospital Research Institute), Ottawa, ON, Canada; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada. Electronic address:

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http://dx.doi.org/10.1378/chest.14-2169DOI Listing
August 2015

A lymphocyte-dependent mode of action for imatinib mesylate in experimental pulmonary hypertension.

Am J Pathol 2013 May 19;182(5):1541-51. Epub 2013 Mar 19.

Terrence Donnelly Cardiovascular Research Laboratories, St. Michael's Hospital, Toronto, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S00029440130011
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http://dx.doi.org/10.1016/j.ajpath.2013.01.031DOI Listing
May 2013

Tie2-dependent neovascularization of the ischemic hindlimb is mediated by angiopoietin-2.

PLoS One 2012 25;7(9):e43568. Epub 2012 Sep 25.

Terrence Donnelly Research Laboratories, Division of Cardiology, St. Michael's Hospital, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0043568PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458045PMC
April 2013

Innate immunity in the therapeutic actions of endothelial progenitor cells in pulmonary hypertension.

Am J Respir Cell Mol Biol 2010 Nov 7;43(5):546-54. Epub 2009 Dec 7.

Ottawa Hospital Research Institute and the University of Ottawa, Ottawa, Ontario, K1H 8L6 Canada.

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http://dx.doi.org/10.1165/rcmb.2009-0152OCDOI Listing
November 2010

Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis.

Am J Respir Crit Care Med 2010 Oct 17;182(8):1047-57. Epub 2010 Jun 17.

The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada, K1H 8L6.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.201001-0010O
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http://dx.doi.org/10.1164/rccm.201001-0010OCDOI Listing
October 2010

The enzymatic degradation of hyaluronan is associated with disease progression in experimental pulmonary hypertension.

Am J Physiol Lung Cell Mol Physiol 2010 Feb 13;298(2):L148-57. Epub 2009 Nov 13.

Terrence Donnelly Cardiovascular Research Laboratories, Rm. 8-038, Queen Wing, St. Michael's Hospital, 30 Bond St., Toronto, Ontario, M5B 1W8 Canada.

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http://dx.doi.org/10.1152/ajplung.00097.2009DOI Listing
February 2010

The angiopietin-1-Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice.

J Exp Med 2009 Sep 8;206(10):2221-34. Epub 2009 Sep 8.

Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5G 1L5, Canada.

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http://dx.doi.org/10.1084/jem.20090389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757882PMC
September 2009

Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions.

Am J Physiol Lung Cell Mol Physiol 2008 Nov 22;295(5):L744-55. Epub 2008 Aug 22.

Vanderbilt University, 1161 21st Avenue S., Nashville, TN 37232-2650, USA.

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http://dx.doi.org/10.1152/ajplung.90255.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584890PMC
November 2008

Oxygen regulation of arterial smooth muscle cell proliferation and survival.

Am J Physiol Heart Circ Physiol 2008 Feb 30;294(2):H839-52. Epub 2007 Nov 30.

Institute of Medical Science, University of Toronto, St. Michael's Hospital, Ontario, Canada.

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http://www.physiology.org/doi/10.1152/ajpheart.00587.2007
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http://dx.doi.org/10.1152/ajpheart.00587.2007DOI Listing
February 2008

Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1.

PLoS Med 2007 Sep;4(9):e269

The Terrence Donnelly Research Laboratories, Division of Cardiology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1371/journal.pmed.0040269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1961632PMC
September 2007

Cell-based angiopoietin-1 gene therapy for acute lung injury.

Am J Respir Crit Care Med 2007 May 22;175(10):1014-26. Epub 2007 Feb 22.

St. Michael's Hospital, Toronto, ON, M5B 1W8, Canada.

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http://dx.doi.org/10.1164/rccm.200609-1370OCDOI Listing
May 2007

Microvascular regeneration in established pulmonary hypertension by angiogenic gene transfer.

Am J Respir Cell Mol Biol 2006 Aug 16;35(2):182-9. Epub 2006 Mar 16.

Division of Cardiology, The Terrence Donnelly Vascular Biology Laboratories, St. Michael's Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1165/rcmb.2005-0115OCDOI Listing
August 2006

Role of angiopoietin-1 in experimental and human pulmonary arterial hypertension.

Chest 2005 Dec;128(6 Suppl):633S-642S

Terrence Donnelly Heart Centre, Division of Cardiology, St. Michael's Hospital, Queen Wing, Toronto, ON, Canada, M5B 1W8.

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http://journal.publications.chestnet.org/data/Journals/CHEST
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http://linkinghub.elsevier.com/retrieve/pii/S001236921531042
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http://dx.doi.org/10.1378/chest.128.6_suppl.633SDOI Listing
December 2005

WASp verprolin homology, cofilin homology, and acidic region domain-mediated actin polymerization is required for T cell development.

Proc Natl Acad Sci U S A 2002 Feb 12;99(4):2240-5. Epub 2002 Feb 12.

Department of Medicine, University of Toronto, Toronto, ON, Canada M5G 1X5.

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http://dx.doi.org/10.1073/pnas.042686099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC122349PMC
February 2002