Publications by authors named "Yunzeng Zou"

100Publications

Rosuvastatin protects against coronary microembolization-induced cardiac injury via inhibiting NLRP3 inflammasome activation.

Cell Death Dis 2021 Jan 12;12(1):78. Epub 2021 Jan 12.

Department of Cardiology, Zhongshan Hospital, Fudan University; Shanghai Institute of Cardiovascular Diseases; National Clinical Research Center for Interventional Medicine, Shanghai, China.

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January 2021

Variations in Energy Metabolism Precede Alterations in Cardiac Structure and Function in Hypertrophic Preconditioning.

Front Cardiovasc Med 2020 11;7:602100. Epub 2020 Dec 11.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

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December 2020

Low-density lipoprotein receptor-related protein 6 regulates cardiomyocyte-derived paracrine signaling to ameliorate cardiac fibrosis.

Theranostics 2021 1;11(3):1249-1268. Epub 2021 Jan 1.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.

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January 2021

Pressure overload promotes cystatin C secretion of cardiomyocytes to regulate the MAPK signaling pathway and mediate cardiac hypertrophy.

Ann Transl Med 2020 Nov;8(22):1514

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.

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November 2020

Disruption of STAT6 Signal Promotes Cardiac Fibrosis Through the Mobilization and Transformation of CD11b Immature Myeloid Cells.

Front Physiol 2020 22;11:579712. Epub 2020 Oct 22.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.

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October 2020

Cardiomyocyte-restricted high-mobility group box 1 (HMGB1) deletion leads to small heart and glycolipid metabolic disorder through GR/PGC-1α signalling.

Cell Death Discov 2020 20;6:106. Epub 2020 Oct 20.

Shanghai Institute of Cardiovascular Diseases, Shanghai Clinical Bioinformatics Research Institute, Zhongshan Hospital, Shanghai Medical College of Fudan University, Shanghai, China.

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October 2020

Low density lipoprotein receptor related protein 6 (LRP6) protects heart against oxidative stress by the crosstalk of HSF1 and GSK3β.

Redox Biol 2020 Oct 25;37:101699. Epub 2020 Aug 25.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, and Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China. Electronic address:

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October 2020

Hypoxia-challenged MSC-derived exosomes deliver miR-210 to attenuate post-infarction cardiac apoptosis.

Stem Cell Res Ther 2020 06 8;11(1):224. Epub 2020 Jun 8.

Department of Cardiology, Zhongshan Hospital, Fudan University, 1609 Xietu Road, Shanghai, 200032, China.

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June 2020

Clinical analysis of sinus bradycardia in patients with severe COVID-19 pneumonia.

Crit Care 2020 May 26;24(1):257. Epub 2020 May 26.

Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, 180 Feng Lin Rd., Shanghai, 200032, China.

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May 2020

Interleukin-11 regulates the fate of adipose-derived mesenchymal stem cells via STAT3 signalling pathways.

Cell Prolif 2020 May 9;53(5):e12771. Epub 2020 Apr 9.

Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.

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May 2020

The diagonal branches and outcomes in patients with anterior ST- elevation myocardial infarction.

BMC Cardiovasc Disord 2020 03 4;20(1):108. Epub 2020 Mar 4.

Department of cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.

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March 2020

Disruption of histamine/HR signaling pathway represses cardiac differentiation and maturation of human induced pluripotent stem cells.

Stem Cell Res Ther 2020 03 4;11(1):27. Epub 2020 Mar 4.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China.

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March 2020

Hyperlipidemia inhibits the protective effect of lisinopril after myocardial infarction via activation of dendritic cells.

J Cell Mol Med 2020 Apr 19;24(7):4082-4091. Epub 2020 Feb 19.

Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.

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April 2020

Characterization of a nap1l1 transgenic reporter in zebrafish.

Gene 2020 Apr 24;735:144388. Epub 2020 Jan 24.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institute of Biomedical Sciences, Fudan University, Shanghai 200032, PR China. Electronic address:

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April 2020

Heat shock transcription factor 1 regulates exercise-induced myocardial angiogenesis after pressure overload via HIF-1α/VEGF pathway.

J Cell Mol Med 2020 02 12;24(3):2178-2188. Epub 2020 Jan 12.

Department of Kinesiology, Institute of Physical Education, Shanghai Normal University, Shanghai, China.

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February 2020

Overexpression of the histidine triad nucleotide-binding protein 2 protects cardiac function in the adult mice after acute myocardial infarction.

Acta Physiol (Oxf) 2020 04 21;228(4):e13439. Epub 2020 Jan 21.

Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.

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April 2020

Cardiac-specific LRP6 knockout induces lipid accumulation through Drp1/CPT1b pathway in adult mice.

Cell Tissue Res 2020 Apr 7;380(1):143-153. Epub 2019 Dec 7.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, and Institutes of Biomedical Sciences, Fudan University, 180 Feng Lin Road, Shanghai, 200032, China.

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April 2020

Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical Stress.

Dis Markers 2019 27;2019:5058313. Epub 2019 Oct 27.

Shanghai Institute of Cardiovascular Diseases, Shanghai Clinical Bioinformatics Research Institute, Zhongshan Hospital, Shanghai Medical College of Fudan University, Shanghai, China.

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April 2020

Expression of nucleosome assembly protein 1 like genes in zebrafish embryos.

Gene Expr Patterns 2020 01 24;35:119076. Epub 2019 Oct 24.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institute of Biomedical Sciences, Fudan University, Shanghai 200032, PR China. Electronic address:

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January 2020

Effects of Adiponectin on Diastolic Function in Mice Underwent Transverse Aorta Constriction.

J Cardiovasc Transl Res 2020 04 16;13(2):225-237. Epub 2019 Oct 16.

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.

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April 2020

Lipoprotein receptor-related protein 6 is required to maintain intercalated disk integrity.

Genes Cells 2019 Dec 10;24(12):789-800. Epub 2019 Nov 10.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institute of Biomedical Sciences, Fudan University, Shanghai, China.

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December 2019

HMGB1 enhances mechanical stress-induced cardiomyocyte hypertrophy in vitro via the RAGE/ERK1/2 signaling pathway.

Int J Mol Med 2019 Sep 16;44(3):885-892. Epub 2019 Jul 16.

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Shanghai Medical College of Fudan University, Shanghai 200032, P.R. China.

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September 2019

Loss of Rubicon ameliorates doxorubicin-induced cardiotoxicity through enhancement of mitochondrial quality.

Int J Cardiol 2019 12 24;296:129-135. Epub 2019 Jul 24.

Bio-X-Renji Hospital Research Center, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China. Electronic address:

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December 2019

Gender Differences in Cardiac Hypertrophy.

J Cardiovasc Transl Res 2020 02 15;13(1):73-84. Epub 2019 Aug 15.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, 180 Feng Lin Road, Shanghai, 200032, China.

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February 2020

Peroxisome Proliferator-Activated Receptor-γ Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p.

PPAR Res 2019 1;2019:2715176. Epub 2019 Jul 1.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai 200032, China.

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July 2019

Gut microbe-derived metabolite trimethylamine N-oxide accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis.

J Mol Cell Cardiol 2019 09 9;134:119-130. Epub 2019 Jul 9.

Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China; Institute of Biomedical Sciences, Fudan University, Shanghai, China; Shanghai Institute of Cardiovascular Diseases, Shanghai Cardiovascular Medical Center, Institute of Pan-vascular Medicine, Fudan University, Shanghai, China. Electronic address:

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September 2019

VEGFR endocytosis regulates the angiogenesis in a mouse model of hindlimb ischemia.

J Thorac Dis 2019 May;11(5):1849-1859

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

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May 2019

Cardiac Proteome Profiling in Ischemic and Dilated Cardiomyopathy Mouse Models.

Front Physiol 2019 18;10:750. Epub 2019 Jun 18.

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.

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June 2019

ACE inhibitor suppresses cardiac remodeling after myocardial infarction by regulating dendritic cells and AT receptor-mediated mechanism in mice.

Biomed Pharmacother 2019 Jun 8;114:108660. Epub 2019 Apr 8.

Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China; Shanghai Institute of Cardiovascular Diseases, Shanghai, China. Electronic address:

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June 2019

FTY720 alleviates coxsackievirus B3-induced myocarditis and inhibits viral replication through regulating sphingosine 1-phosphate receptors and AKT/caspase-3 pathways.

J Cell Physiol 2019 08 6;234(10):18029-18040. Epub 2019 Mar 6.

Department of Cardiology, Key Laboratory of Viral Heart Diseases, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Ministry of Public Health, Shanghai, China.

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August 2019

SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress.

PLoS One 2019 13;14(2):e0211796. Epub 2019 Feb 13.

Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, and The Molecular and Cell Biology Lab, Institutes of Biomedical Sciences, Key Laboratory of Medical Epigenetics and Metabolism, Shanghai Medical College, Fudan University, Shanghai, China.

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November 2019

Predictive Value of CHADS-VASc Score for Ischemic Events in Patients Undergoing Percutaneous Coronary Intervention.

Angiology 2019 10 15;70(9):878-886. Epub 2018 Oct 15.

1 Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.

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October 2019

Aldehyde dehydrogenase 2 deficiency promotes atherosclerotic plaque instability through accelerating mitochondrial ROS-mediated vascular smooth muscle cell senescence.

Biochim Biophys Acta Mol Basis Dis 2019 07 11;1865(7):1782-1792. Epub 2018 Oct 11.

Shanghai Institute of Cardiovascular Diseases, Department of Cardiology, Zhongshan Hospital, Fudan University Shanghai 200032, China. Electronic address:

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July 2019

Proteomics Analysis of Myocardial Tissues in a Mouse Model of Coronary Microembolization.

Front Physiol 2018 19;9:1318. Epub 2018 Sep 19.

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.

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September 2018

Clinical significance of increased urotensin II levels in acute myocardial infarction.

Discov Med 2018 08;26(141):7-20

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.

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August 2018

Mechanical stresses induce paracrine β-2 microglobulin from cardiomyocytes to activate cardiac fibroblasts through epidermal growth factor receptor.

Clin Sci (Lond) 2018 08 30;132(16):1855-1874. Epub 2018 Aug 30.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institute of Biomedical Sciences, Fudan University, Shanghai 200032, China

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August 2018

Evaluation of the performance of serum miRNAs as normalizers in microRNA studies focused on cardiovascular disease.

J Thorac Dis 2018 May;10(5):2599-2607

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Science, Fudan University, Shanghai 200032, China.

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May 2018

Heat-shock transcription factor 1 is critically involved in the ischaemia-induced cardiac hypertrophy via JAK2/STAT3 pathway.

J Cell Mol Med 2018 09 11;22(9):4292-4303. Epub 2018 Jul 11.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biological Science, Fudan University, Shanghai, China.

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September 2018

The diagnostic values of circulating miRNAs for hypertension and bioinformatics analysis.

Biosci Rep 2018 08 29;38(4). Epub 2018 Aug 29.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Science, Fudan University, Shanghai, China

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August 2018

Histamine deficiency aggravates cardiac injury through miR-206/216b-Atg13 axis-mediated autophagic-dependant apoptosis.

Cell Death Dis 2018 06 7;9(6):694. Epub 2018 Jun 7.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China.

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June 2018

Knockdown of LRP6 activates Drp1 to inhibit survival of cardiomyocytes during glucose deprivation.

Biomed Pharmacother 2018 Jul 7;103:1408-1414. Epub 2018 May 7.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.

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July 2018

Effects of different doses of granulocyte colony-stimulating factor mobilization therapy on ischemic cardiomyopathy.

Sci Rep 2018 04 12;8(1):5922. Epub 2018 Apr 12.

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Shanghai, 200032, China.

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April 2018

Liraglutide attenuates NLRP3 inflammasome-dependent pyroptosis via regulating SIRT1/NOX4/ROS pathway in H9c2 cells.

Biochem Biophys Res Commun 2018 05 23;499(2):267-272. Epub 2018 Mar 23.

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China. Electronic address:

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May 2018

Temporal and spatial expression of fgfbp genes in zebrafish.

Gene 2018 Jun 16;659:128-136. Epub 2018 Mar 16.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institute of Biomedical Sciences, Fudan University, Shanghai 200032, PR China. Electronic address:

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June 2018

Neural cell adhesion molecule-1 may be a new biomarker of coronary artery disease.

Int J Cardiol 2018 04;257:238-242

Shanghai Institute of Cardiovascular Diseases, Shanghai Institute of Clinical Bioinformatics, Zhongshan Hospital, Shanghai Medical College of Fudan University, China. Electronic address:

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April 2018

Identification of a Common Different Gene Expression Signature in Ischemic Cardiomyopathy.

Genes (Basel) 2018 Jan 22;9(1). Epub 2018 Jan 22.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, 180 Fenglin Road, Shanghai 200032, China.

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January 2018

Riboflavin attenuates myocardial injury via LSD1-mediated crosstalk between phospholipid metabolism and histone methylation in mice with experimental myocardial infarction.

J Mol Cell Cardiol 2018 02 8;115:115-129. Epub 2018 Jan 8.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China. Electronic address:

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February 2018

Case report: improvement of cardiac remodeling with shock wave therapy of a patient with ischemic cardiomyopathy.

J Thorac Dis 2017 Dec;9(12):E1104-E1109

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

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December 2017

Differential cardiac hypertrophy and signaling pathways in pressure versus volume overload.

Am J Physiol Heart Circ Physiol 2018 03 1;314(3):H552-H562. Epub 2017 Dec 1.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University , Shanghai , China.

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March 2018

Ryanodine Receptor Type 2 Plays a Role in the Development of Cardiac Fibrosis under Mechanical Stretch Through TGFβ-1.

Int Heart J 2017 Dec 22;58(6):957-961. Epub 2017 Nov 22.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institute of Biomedical Sciences, Fudan University.

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December 2017

Evolution of Vertebrate Ryanodine Receptors Family in Relation to Functional Divergence and Conservation.

Int Heart J 2017 Dec 17;58(6):969-977. Epub 2017 Nov 17.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University.

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December 2017

Sphingosine 1-phosphate alleviates Coxsackievirus B3-induced myocarditis by increasing invariant natural killer T cells.

Exp Mol Pathol 2017 10 3;103(2):210-217. Epub 2017 Oct 3.

Key Laboratory of Viral Heart Diseases, Ministry of Public Health, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China. Electronic address:

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October 2017

Lercanidipine attenuates angiotensin II-induced cardiomyocyte hypertrophy by blocking calcineurin-NFAT3 and CaMKII-HDAC4 signaling.

Mol Med Rep 2017 Oct 10;16(4):4545-4552. Epub 2017 Aug 10.

Department of Pharmacy, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.

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October 2017

LCZ696 improves cardiac function via alleviating Drp1-mediated mitochondrial dysfunction in mice with doxorubicin-induced dilated cardiomyopathy.

J Mol Cell Cardiol 2017 07 15;108:138-148. Epub 2017 Jun 15.

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases,Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai 200032, China. Electronic address:

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July 2017

Histamine promotes the differentiation of macrophages from CD11b myeloid cells and formation of foam cells through a Stat6-dependent pathway.

Atherosclerosis 2017 Aug 23;263:42-52. Epub 2017 May 23.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China. Electronic address:

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August 2017

miR-181a and miR-150 regulate dendritic cell immune inflammatory responses and cardiomyocyte apoptosis via targeting JAK1-STAT1/c-Fos pathway.

J Cell Mol Med 2017 Nov 9;21(11):2884-2895. Epub 2017 Jun 9.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.

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November 2017

Mitochondrial aldehyde dehydrogenase-2 deficiency compromises therapeutic effect of ALDH bright cell on peripheral ischemia.

Redox Biol 2017 10 29;13:196-206. Epub 2017 May 29.

Institute of Biomedical Science, Fudan University, Shanghai 200032, China; Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Shanghai 200032, China. Electronic address:

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October 2017

Ultrasound biomicroscopy validation of a murine model of cardiac hypertrophic preconditioning: comparison with a hemodynamic assessment.

Am J Physiol Heart Circ Physiol 2017 Jul 28;313(1):H138-H148. Epub 2017 Apr 28.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, People's Republic of China;

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July 2017

The Essential Role of Pin1 via NF-κB Signaling in Vascular Inflammation and Atherosclerosis in ApoE Mice.

Int J Mol Sci 2017 Mar 16;18(3). Epub 2017 Mar 16.

Shanghai Institute of Cardiovascular Diseases, Institute of Clinical Science, Zhongshan Hospital, Shanghai Medical College, Fudan University, 180 Fenglin Road, Shanghai 200032, China.

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March 2017

Aggravated myocardial infarction-induced cardiac remodeling and heart failure in histamine-deficient mice.

Sci Rep 2017 03 8;7:44007. Epub 2017 Mar 8.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, and Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China.

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March 2017

UVRAG Deficiency Exacerbates Doxorubicin-Induced Cardiotoxicity.

Sci Rep 2017 02 22;7:43251. Epub 2017 Feb 22.

Bio-X-Renji Hospital Research Center, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

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February 2017

Dendritic cells derived exosomes migration to spleen and induction of inflammation are regulated by CCR7.

Sci Rep 2017 02 22;7:42996. Epub 2017 Feb 22.

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.

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February 2017

Heat shock transcription factor 1 protects against pressure overload-induced cardiac fibrosis via Smad3.

J Mol Med (Berl) 2017 04 13;95(4):445-460. Epub 2017 Jan 13.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biological Science, Fudan University, Shanghai, 200032, China.

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April 2017

Circulating miR-181a as a Potential Novel Biomarker for Diagnosis of Acute Myocardial Infarction.

Cell Physiol Biochem 2016 21;40(6):1591-1602. Epub 2016 Dec 21.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.

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February 2017

Diagnostic Utility of ANG in Coronary Heart Disease Complicating Chronic Heart Failure: A Cross-Sectional Study.

Dis Markers 2016 31;2016:2740826. Epub 2016 Oct 31.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Shanghai Medical College of Fudan University, Shanghai 200032, China.

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February 2017

Aldehyde dehydrogenase 2 deficiency negates chronic low-to-moderate alcohol consumption-induced cardioprotecion possibly via ROS-dependent apoptosis and RIP1/RIP3/MLKL-mediated necroptosis.

Biochim Biophys Acta Mol Basis Dis 2017 08 11;1863(8):1912-1918. Epub 2016 Nov 11.

Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Institute of Biomedical Science, Fudan University, Shanghai 200032, China. Electronic address:

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August 2017

Ischemic Postconditioning-Regulated miR-499 Protects the Rat Heart Against Ischemia/Reperfusion Injury by Inhibiting Apoptosis through PDCD4.

Cell Physiol Biochem 2016 11;39(6):2364-2380. Epub 2016 Nov 11.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.

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February 2017

Opposing Roles of Wnt Inhibitors IGFBP-4 and Dkk1 in Cardiac Ischemia by Differential Targeting of LRP5/6 and β-catenin.

Circulation 2016 Dec 1;134(24):1991-2007. Epub 2016 Nov 1.

From Clinical and Translational Research Center Shanghai East Hospital, Key Laboratory of Arrhythmias, Ministry of Education, Tongji University School of Medicine, China (D.W., Jinhui Peng, D.-n.R., J.C., Y. Zhu, Y.Y., H.Y., E.M., Y.C., Zhongmin Liu, S.L., L.A., W.Z.); Department of Orthopedics, Changzheng Hospital, Shanghai, China (Jinhui Peng, Q.Q.); Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China (L.Q., Jun Peng); Shanghai Key Laboratory of Signaling and Disease Research, The School of Life Sciences and Technology, Tongji University, China (Zhenping Liu, C.J.); State Key Laboratory of Genetic Engineering, Department of Genetics, School of Life Sciences, Fudan University, Shanghai, China (Y.Y., T.Z.); and Institutes of Biomedical Sciences, Fudan University, Shanghai, China (J.W., Y. Zou).

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December 2016

Naoxintong attenuates Ischaemia/reperfusion Injury through inhibiting NLRP3 inflammasome activation.

J Cell Mol Med 2017 01 26;21(1):4-12. Epub 2016 Oct 26.

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.

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January 2017

Mitochondrial aldehyde dehydrogenase 2 deficiency aggravates energy metabolism disturbance and diastolic dysfunction in diabetic mice.

J Mol Med (Berl) 2016 11 3;94(11):1229-1240. Epub 2016 Aug 3.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Fenglin Road 180, Shanghai, 200032, People's Republic of China.

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November 2016

Exosomes derived from mature dendritic cells increase endothelial inflammation and atherosclerosis via membrane TNF-α mediated NF-κB pathway.

J Cell Mol Med 2016 12 12;20(12):2318-2327. Epub 2016 Aug 12.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.

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December 2016

Dual roles of calpain in facilitating Coxsackievirus B3 replication and prompting inflammation in acute myocarditis.

Int J Cardiol 2016 Oct 9;221:1123-31. Epub 2016 Jul 9.

Department of Cardiovascular Diseases, Key Laboratory of Viral Heart Diseases, Ministry of Public Health, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China. Electronic address:

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October 2016

Advanced glycation end products impair the functions of saphenous vein but not thoracic artery smooth muscle cells through RAGE/MAPK signalling pathway in diabetes.

J Cell Mol Med 2016 10 14;20(10):1945-55. Epub 2016 Jun 14.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.

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October 2016

Aldehyde dehydrogenase 2 deficiency blunts compensatory cardiac hypertrophy through modulating Akt phosphorylation early after transverse aorta constriction in mice.

Biochim Biophys Acta 2016 09 27;1862(9):1587-93. Epub 2016 May 27.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, PR China; Institute of Biomedical Science, Fudan University, Shanghai 200032, PR China. Electronic address:

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September 2016

The effects of different angiotensin II type 1 receptor blockers on the regulation of the ACE-AngII-AT1 and ACE2-Ang(1-7)-Mas axes in pressure overload-induced cardiac remodeling in male mice.

J Mol Cell Cardiol 2016 08 19;97:180-90. Epub 2016 May 19.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, People's Republic of China; Institute of Biomedical Sciences, Fudan University, Shanghai 200032, People's Republic of China. Electronic address:

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August 2016

Effects of Fine Particulate Matter (PM2.5) on Systemic Oxidative Stress and Cardiac Function in ApoE(-/-) Mice.

Int J Environ Res Public Health 2016 05 12;13(5). Epub 2016 May 12.

Department of Environmental Health, School of Public Health and Key Laboratory of Public Health Safety, Fudan University, Shanghai 200032, China.

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May 2016

Mechanical Stress Regulates Endothelial Progenitor Cell Angiogenesis Through VEGF Receptor Endocytosis.

Int Heart J 2016 May 28;57(3):356-62. Epub 2016 Apr 28.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University.

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May 2016

Nucleosome Assembly Protein 1-Like 1 (Nap1l1) Regulates the Proliferation of Murine Induced Pluripotent Stem Cells.

Cell Physiol Biochem 2016 29;38(1):340-50. Epub 2016 Jan 29.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

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October 2016

Exosomes derived from dendritic cells improve cardiac function via activation of CD4(+) T lymphocytes after myocardial infarction.

J Mol Cell Cardiol 2016 Feb 30;91:123-33. Epub 2015 Dec 30.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, 200032 Shanghai, PR China. Electronic address:

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February 2016

Extracellular high-mobility group box 1 mediates pressure overload-induced cardiac hypertrophy and heart failure.

J Cell Mol Med 2016 Mar 9;20(3):459-70. Epub 2015 Dec 9.

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Shanghai Medical College of Fudan University, Shanghai, China.

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March 2016

Mas receptor mediates cardioprotection of angiotensin-(1-7) against Angiotensin II-induced cardiomyocyte autophagy and cardiac remodelling through inhibition of oxidative stress.

J Cell Mol Med 2016 Jan 30;20(1):48-57. Epub 2015 Oct 30.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institute of Biomedical Science, Fudan University, Shanghai, China.

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January 2016

Mitochondrial Aldehyde Dehydrogenase 2 Regulates Revascularization in Chronic Ischemia: Potential Impact on the Development of Coronary Collateral Circulation.

Arterioscler Thromb Vasc Biol 2015 Oct 27;35(10):2196-206. Epub 2015 Aug 27.

From the Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital (X.L., H.Z., P.W., L.S., L.X., C.S., F.F., C.W., K.H., Y.Z., J.G., J.R., A.S.), Institute of Biomedical Science (X.S., L.X., X.M., Y.Z., J.G., A.S.), Department of Cardiology, Huashan Hospital (Z.D.), Fudan University, Shanghai, P.R. China; Center for Cardiovascular Research and Alternative Medicine, School of Pharmacy, University of Wyoming College of Health Sciences, Laramie (X.L., J.R.); Dongfang Hospital, Tongji University, Shanghai, P.R. China (H.L.); and Department of Cardiology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P.R. China (J.Z.).

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October 2015

Identification of Amino Acid Residues in Angiotensin II Type 1 Receptor Sensing Mechanical Stretch and Function in Cardiomyocyte Hypertrophy.

Cell Physiol Biochem 2015 17;37(1):105-16. Epub 2015 Aug 17.

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

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May 2016

Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis.

Sci Rep 2015 Aug 17;5:13131. Epub 2015 Aug 17.

1] Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, 200032, China [2] Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

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August 2015

Letter to the editor: When what you see might not be what you get: prudent considerations of anesthetics for murine echocardiography.

Am J Physiol Heart Circ Physiol 2015 Jun;308(12):H1612-3

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, China

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June 2015