Publications by authors named "Yun-Yong Park"

79Publications

A biocomposite-based rapid sampling assay for circulating cell-free DNA in liquid biopsy samples from human cancers.

Sci Rep 2020 Sep 10;10(1):14932. Epub 2020 Sep 10.

Department of Convergence Medicine, Asan Medical Center, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-020-72163-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484795PMC
September 2020

A novel nanoparticle-based theranostic agent targeting LRP-1 enhances the efficacy of neoadjuvant radiotherapy in colorectal cancer.

Biomaterials 2020 Oct 27;255:120151. Epub 2020 May 27.

Center for Advancing Cancer Therapeutics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, South Korea; Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2020.120151DOI Listing
October 2020

An RNA-binding-protein, NONO governs energy metabolism by regulating NAMPT in lung cancer.

Biochem Biophys Res Commun 2020 Jul 19;528(2):376-382. Epub 2020 Feb 19.

Department of Convergence Medicine, University of Ulsan College of Medicine, Seoul, South Korea; Asan Institute for Life Sciences, Asan Medical Center, Seoul, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2020.01.011DOI Listing
July 2020

Branchial cleft cyst in the parotid gland in a human immunodeficiency virus-negative patient.

Arch Craniofac Surg 2019 Jun 20;20(3):191-194. Epub 2019 Jun 20.

Department of Plastic and Reconstructive Surgery, Hanyang University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.7181/acfs.2019.00031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615421PMC
June 2019

Retraction notice to "Polo-like kinase 2 gene expression is regulated by the orphan nuclear receptor estrogen receptor-related receptor gamma (ERRγ)" [Biochem. Biophys. Res. Commun. 362 (1) (2007) 107-113].

Biochem Biophys Res Commun 2019 Aug;515(4):725

Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, 500-757, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2019.03.175DOI Listing
August 2019

Loss of PKM2 in Lgr5 intestinal stem cells promotes colitis-associated colorectal cancer.

Sci Rep 2019 04 17;9(1):6212. Epub 2019 Apr 17.

Mucosal Immunology Laboratory, Department of Convergence Medicine, University of Ulsan College of Medicine/Asan Medical Center, Seoul, Republic of Korea.

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http://www.nature.com/articles/s41598-019-42707-8
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http://dx.doi.org/10.1038/s41598-019-42707-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470145PMC
April 2019

Flap selection for reconstruction of wide palatal defect after cancer surgery.

Arch Craniofac Surg 2019 Feb 7;20(1):17-23. Epub 2019 Feb 7.

Department of Plastic and Reconstructive Surgery, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.

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http://dx.doi.org/10.7181/acfs.2018.02061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411529PMC
February 2019

Multiplane Forehead Shortening: Sparing the Frontalis Muscle and Supraorbital Nerve.

Plast Reconstr Surg 2019 02;143(2):405-413

Seoul and Guri, Republic of Korea From the ATOP Plastic Surgery Clinic; and the Department of Plastic and Reconstructive Surgery, Hanyang University Guri Hospital, Hanyang University College of Medicine.

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http://dx.doi.org/10.1097/PRS.0000000000005271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358193PMC
February 2019

Retraction Note: Distinct Repressive Properties of the Mammalian and Fish Orphan Nuclear Receptors SHP and DAX-1.

Mol Cells 2018 Dec;41(12):1081

Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju 500-757, Korea.

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http://dx.doi.org/10.14348/molcells.2018.3221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315315PMC
December 2018

An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRγ.

Nucleic Acids Res 2019 Feb;47(3):1604

Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, 500-757, Republic of Korea.

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http://dx.doi.org/10.1093/nar/gky1272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379710PMC
February 2019

Microbiota-Derived Lactate Accelerates Intestinal Stem-Cell-Mediated Epithelial Development.

Cell Host Microbe 2018 12;24(6):833-846.e6

Mucosal Immunology Laboratory, Department of Convergence Medicine, University of Ulsan College of Medicine/Asan Medical Center, Seoul, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19313128183055
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http://dx.doi.org/10.1016/j.chom.2018.11.002DOI Listing
December 2018

Corrigendum: An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRγ.

Nucleic Acids Res 2018 12;46(22):12192-12193

Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, 500-757, Republic of Korea.

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http://dx.doi.org/10.1093/nar/gky1145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294557PMC
December 2018

Author Correction: Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer.

Nat Commun 2018 08 31;9(1):3599. Epub 2018 Aug 31.

ASAN Institute for Life Sciences, ASAN Medical Center, University of Ulsan College of Medicine, Seoul, 05505, Republic of Korea.

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http://dx.doi.org/10.1038/s41467-018-06061-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119198PMC
August 2018

Fibroblast-associated tumour microenvironment induces vascular structure-networked tumouroid.

Sci Rep 2018 02 5;8(1):2365. Epub 2018 Feb 5.

Biomedical Engineering Research Center, Asan Medical Center, Seoul, Korea.

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http://dx.doi.org/10.1038/s41598-018-20886-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799156PMC
February 2018

Verteporfin inhibits gastric cancer cell growth by suppressing adhesion molecule FAT1.

Oncotarget 2017 Nov 19;8(58):98887-98897. Epub 2017 Oct 19.

Asan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea.

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http://dx.doi.org/10.18632/oncotarget.21946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716775PMC
November 2017

Relief of YAP-mediated inhibition by IKKɛ promotes innate antiviral immunity.

Cell Mol Immunol 2018 Jun 23;15(6):642-644. Epub 2017 Oct 23.

Department of Microbiology, Asan Medical Center, University of Ulsan College of Medicine, 05505, Seoul, Korea.

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http://dx.doi.org/10.1038/cmi.2017.97DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078990PMC
June 2018

The resident pathobiont Staphylococcus xylosus in Nfkbiz-deficient skin accelerates spontaneous skin inflammation.

Sci Rep 2017 07 24;7(1):6348. Epub 2017 Jul 24.

Mucosal Immunology Laboratory, Department of Convergence Medicine, University of Ulsan College of Medicine/Asan Medical Center, Seoul, Korea.

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http://dx.doi.org/10.1038/s41598-017-05740-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524713PMC
July 2017

A strategy for actualization of active targeting nanomedicine practically functioning in a living body.

Biomaterials 2017 Oct 30;141:136-148. Epub 2017 Jun 30.

Institute for Innovative Cancer Research, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, South Korea; Center for Advancing Cancer Therapeutics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, South Korea; Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2017.06.037DOI Listing
October 2017

SOHLH2 is essential for synaptonemal complex formation during spermatogenesis in early postnatal mouse testes.

Sci Rep 2016 Feb 12;6:20980. Epub 2016 Feb 12.

Department of Biomedical Science, CHA University, Seongnam-si, Gyeonggi-do 463-400, Republic of Korea.

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http://dx.doi.org/10.1038/srep20980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751484PMC
February 2016

Inactivation of Hippo Pathway Is Significantly Associated with Poor Prognosis in Hepatocellular Carcinoma.

Clin Cancer Res 2016 Mar 12;22(5):1256-64. Epub 2015 Oct 12.

Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Kleberg Center for Molecular Markers, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Biochemistry and Molecular Biology, Medical Research Center and Biomedical Science Institute, School of Medicine, Kyung Hee University, Seoul, Korea.

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http://clincancerres.aacrjournals.org/content/early/2015/10/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-15-1447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536176PMC
March 2016

Myristoylation confers noncanonical AMPK functions in autophagy selectivity and mitochondrial surveillance.

Nat Commun 2015 Aug 14;6:7926. Epub 2015 Aug 14.

Department of Systems Biology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ncomms8926DOI Listing
August 2015

Activating CAR and β-catenin induces uncontrolled liver growth and tumorigenesis.

Nat Commun 2015 Feb 9;6:5944. Epub 2015 Feb 9.

Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ncomms6944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324535PMC
February 2015

Genomic predictors for recurrence patterns of hepatocellular carcinoma: model derivation and validation.

PLoS Med 2014 Dec 23;11(12):e1001770. Epub 2014 Dec 23.

Department of Systems Biology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America; Kleberg Center for Molecular Markers, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America; Department of Biochemistry and Molecular Biology, Medical Research Center and Biomedical Science Institute, School of Medicine, Kyung Hee University, Seoul, Korea.

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http://dx.doi.org/10.1371/journal.pmed.1001770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275163PMC
December 2014

Significant association of oncogene YAP1 with poor prognosis and cetuximab resistance in colorectal cancer patients.

Clin Cancer Res 2015 Jan 11;21(2):357-64. Epub 2014 Nov 11.

Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Biochemistry and Molecular Biology, Medical Research Center for Bioreaction to Reactive Oxygen Species and Biomedical Science Institute, School of Medicine, Kyung Hee University, Seoul, Korea.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513664PMC
January 2015

HIG2 promotes colorectal cancer progression via hypoxia-dependent and independent pathways.

Cancer Lett 2013 Dec 2;341(2):159-65. Epub 2013 Aug 2.

Departments of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, United States.

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http://dx.doi.org/10.1016/j.canlet.2013.07.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928010PMC
December 2013

Comparison of prognostic genomic predictors in colorectal cancer.

PLoS One 2013 23;8(4):e60778. Epub 2013 Apr 23.

Department of Systems Biology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060778PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634034PMC
November 2013

Induction of the transcriptional repressor ZBTB4 in prostate cancer cells by drug-induced targeting of microRNA-17-92/106b-25 clusters.

Mol Cancer Ther 2012 Sep 29;11(9):1852-62. Epub 2012 Jun 29.

Institute of Biosciences and Technology, Texas A&M Health Science Center, MD Anderson Cancer Center, The University of Texas, Houston, USA.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-12
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http://dx.doi.org/10.1158/1535-7163.MCT-12-0181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632183PMC
September 2012

FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair.

Carcinogenesis 2012 Oct 10;33(10):1843-53. Epub 2012 May 10.

Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1093/carcin/bgs167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529559PMC
October 2012

Human nuclease/helicase DNA2 alleviates replication stress by promoting DNA end resection.

Cancer Res 2012 Jun 9;72(11):2802-13. Epub 2012 Apr 9.

Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367086PMC
June 2012

Systems biology approaches to decoding the genome of liver cancer.

Cancer Res Treat 2011 Dec 27;43(4):205-11. Epub 2011 Dec 27.

Department of Systems Biology, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA.

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http://dx.doi.org/10.4143/crt.2011.43.4.205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253861PMC
December 2011

Prognostic gene expression signature associated with two molecularly distinct subtypes of colorectal cancer.

Gut 2012 Sep 13;61(9):1291-8. Epub 2011 Oct 13.

Department of Systems Biology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1136/gutjnl-2011-300812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419333PMC
September 2012

Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis.

Proc Natl Acad Sci U S A 2011 Oct 10;108(42):17456-61. Epub 2011 Oct 10.

Department of Systems Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1073/pnas.1114210108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198333PMC
October 2011

ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression.

Cancer Res 2011 Nov 21;71(22):7010-20. Epub 2011 Sep 21.

Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217078PMC
November 2011

Gene expression signature analysis identifies vorinostat as a candidate therapy for gastric cancer.

PLoS One 2011 9;6(9):e24662. Epub 2011 Sep 9.

Division of Cancer Medicine, Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024662PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170379PMC
February 2012

Gene expression signature-based prognostic risk score in gastric cancer.

Clin Cancer Res 2011 Apr 29;17(7):1850-7. Epub 2011 Mar 29.

Department of Systems Biology, Division of Cancer Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77054, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-2180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078023PMC
April 2011

Systems-level analysis of gene expression data revealed NR0B2/SHP as potential tumor suppressor in human liver cancer.

Mol Cells 2010 Nov 16;30(5):485-91. Epub 2010 Sep 16.

Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.

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http://link.springer.com/10.1007/s10059-010-0136-6
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http://dx.doi.org/10.1007/s10059-010-0136-6DOI Listing
November 2010

The orphan nuclear receptor estrogen receptor-related receptor gamma negatively regulates BMP2-induced osteoblast differentiation and bone formation.

J Biol Chem 2009 May 26;284(21):14211-8. Epub 2009 Mar 26.

Dental Science Research Institute and Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju 500-757, Republic of Korea.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M808345200
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http://dx.doi.org/10.1074/jbc.M808345200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682869PMC
May 2009

The orphan nuclear receptor DAX-1 acts as a novel transcriptional corepressor of PPARgamma.

Biochem Biophys Res Commun 2008 May 31;370(2):264-8. Epub 2008 Mar 31.

Hormone Research Center, School of Biological Science and Technology, Chonnam National University, Gwangju 500-757, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2008.03.098DOI Listing
May 2008

EID-1 interacts with orphan nuclear receptor SF-1 and represses its transactivation.

Mol Cells 2007 Dec;24(3):372-7

Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju 500-757, Korea.

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December 2007

Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP.

Diabetes 2008 Feb 1;57(2):306-14. Epub 2007 Oct 1.

Hormone Research Center, School of Biological Sciences & Technology, Chonnam National University, Gwangju, 500-757, Republic of Korea.

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http://dx.doi.org/10.2337/db07-0381DOI Listing
February 2008

Polo-like kinase 2 gene expression is regulated by the orphan nuclear receptor estrogen receptor-related receptor gamma (ERRgamma).

Biochem Biophys Res Commun 2007 Oct 8;362(1):107-113. Epub 2007 Aug 8.

Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju 500-757, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2007.07.170DOI Listing
October 2007

Distinct repressive properties of the mammalian and fish orphan nuclear receptors SHP and DAX-1.

Mol Cells 2007 Jun;23(3):331-9

Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju 500-757, Korea.

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June 2007

Structure and function of the atypical orphan nuclear receptor small heterodimer partner.

Int Rev Cytol 2007 ;261:117-58

Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju 500-757, Korea.

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http://dx.doi.org/10.1016/S0074-7696(07)61003-1DOI Listing
September 2007

Orphan nuclear receptor small heterodimer partner inhibits transforming growth factor-beta signaling by repressing SMAD3 transactivation.

J Biol Chem 2006 Dec 30;281(51):39169-78. Epub 2006 Oct 30.

Hormone Research Center, School of Biological Science and Technology, Chonnam National University, Kwangju 500-757, Republic of Korea.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M605947200
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http://dx.doi.org/10.1074/jbc.M605947200DOI Listing
December 2006

Orphan nuclear receptor Nur77 induces zinc finger protein GIOT-1 gene expression, and GIOT-1 acts as a novel corepressor of orphan nuclear receptor SF-1 via recruitment of HDAC2.

J Biol Chem 2006 Jun 4;281(23):15605-14. Epub 2006 Apr 4.

Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju 500-757, Republic of Korea.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M505937200
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http://dx.doi.org/10.1074/jbc.M505937200DOI Listing
June 2006

An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRgamma.

Nucleic Acids Res 2005 28;33(21):6756-68. Epub 2005 Nov 28.

Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, 500-757, Republic of Korea.

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http://dx.doi.org/10.1093/nar/gki976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1301593PMC
December 2005

Differential role of the loop region between helices H6 and H7 within the orphan nuclear receptors small heterodimer partner and DAX-1.

Mol Endocrinol 2004 May 12;18(5):1082-95. Epub 2004 Feb 12.

Hormone Research Center, Chonnam National University, Gwangju 500-757, Republic of Korea.

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http://dx.doi.org/10.1210/me.2003-0339DOI Listing
May 2004

Synergistic activation of the human orphan nuclear receptor SHP gene promoter by basic helix-loop-helix protein E2A and orphan nuclear receptor SF-1.

Nucleic Acids Res 2003 Dec;31(23):6860-72

Hormone Research Center, Chonnam National University, Kwangju, 500-757, Republic of Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC290273PMC
http://dx.doi.org/10.1093/nar/gkg906DOI Listing
December 2003