Yun You

Yun You

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Yun You

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The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells.

Immunity 2018 09;49(3):504-514.e4

Institute for Immunology, Tsinghua University School of Medicine, Tsinghua, Beijing 100084, China; Tsinghua University-Peking University Joint Center for Life Sciences, Beijing 100084, China. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.08.018DOI Listing
September 2018

Preparation of Colon-Targeted Acetylharpagide Tablets and its Release Properties and .

Front Pharmacol 2018 14;9:832. Epub 2018 Aug 14.

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.

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http://dx.doi.org/10.3389/fphar.2018.00832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103264PMC
August 2018

Ginkgolide B inhibits platelet and monocyte adhesion in TNFα-treated HUVECs under laminar shear stress.

BMC Complement Altern Med 2018 Jul 20;18(1):220. Epub 2018 Jul 20.

MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, China.

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http://dx.doi.org/10.1186/s12906-018-2284-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053749PMC
July 2018

One-way edge modes in a photonic crystal of semiconductor at terahertz frequencies.

Sci Rep 2018 May 25;8(1):8165. Epub 2018 May 25.

Institute of Space Science and Technology, Nanchang University, Nanchang, 330031, China.

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http://dx.doi.org/10.1038/s41598-018-26395-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970209PMC
May 2018

[Development of bioassay method in quality control of traditional Chinese medicine].

Zhongguo Zhong Yao Za Zhi 2018 Feb;43(3):452-456

Resource Center of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

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http://www.cnki.net/kcms/doi/10.19540/j.cnki.cjcmm.20171208.
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http://dx.doi.org/10.19540/j.cnki.cjcmm.20171208.006DOI Listing
February 2018

[Relationship between pre-clinical toxicity and efficacy of traditional Chinese medicine].

Zhongguo Zhong Yao Za Zhi 2017 Oct;42(20):4045-4048

Drug Control Center, China Food and Drug Administration, Beijing 100038, China.

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http://dx.doi.org/10.19540/j.cnki.cjcmm.20170907.001DOI Listing
October 2017

[Pharmacological effect and toxicology of Sophorae Tonkinensis Radix et Rhizoma].

Zhongguo Zhong Yao Za Zhi 2017 Jul;42(13):2439-2442

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

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http://dx.doi.org/10.19540/j.cnki.cjcmm.20170609.012DOI Listing
July 2017

Intravenous leiomyomatosis of the subclavian vein.

J Vasc Surg Venous Lymphat Disord 2017 03 4;5(2):254-256. Epub 2016 Aug 4.

Vascular Surgery Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.

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http://dx.doi.org/10.1016/j.jvsv.2016.03.008DOI Listing
March 2017

[Anti-platelet adhesive effect and mechanisms of Xueshuantong capsules under flow conditions].

Zhongguo Zhong Yao Za Zhi 2017 Jan;42(2):341-346

Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China.

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http://dx.doi.org/10.19540/j.cnki.cjcmm.20161222.014DOI Listing
January 2017

[Simultaneous determination of seven alkaloids and three flavonoids in Sophorae Tonkinensis Radix et Rhizoma by HPLC].

Zhongguo Zhong Yao Za Zhi 2016 Dec;41(24):4628-4634

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

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http://dx.doi.org/10.4268/cjcmm20162423DOI Listing
December 2016

Transport of Corilagin, Gallic Acid, and Ellagic Acid from Fructus Phyllanthi Tannin Fraction in Caco-2 Cell Monolayers.

Evid Based Complement Alternat Med 2016 21;2016:9205379. Epub 2016 Sep 21.

School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China.

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http://dx.doi.org/10.1155/2016/9205379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050390PMC
September 2016

A Vector with a Single Promoter for In Vitro Transcription and Mammalian Cell Expression of CRISPR gRNAs.

PLoS One 2016 5;11(2):e0148362. Epub 2016 Feb 5.

Mouse Genetics Core Facility, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0148362PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744079PMC
July 2016

Dectin-3 Deficiency Promotes Colitis Development due to Impaired Antifungal Innate Immune Responses in the Gut.

PLoS Pathog 2016 06 9;12(6):e1005662. Epub 2016 Jun 9.

Department of Molecular and Cellular Oncology, The University of Texas, MD Anderson Cancer Center, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900642PMC
June 2016

The Genus Phyllanthus: An Ethnopharmacological, Phytochemical, and Pharmacological Review.

Evid Based Complement Alternat Med 2016 20;2016:7584952. Epub 2016 Apr 20.

School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China.

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http://dx.doi.org/10.1155/2016/7584952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854999PMC
May 2016

[Balance between cardiovascular pharmacological and hemolytic effects of saponins of Panax notogenseng].

Zhongguo Zhong Yao Za Zhi 2016 Mar;41(5):818-822

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

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http://dx.doi.org/10.4268/cjcmm20160510DOI Listing
March 2016

[Anti-platelet aggregation bioassay based quality control for XST capsules].

Zhongguo Zhong Yao Za Zhi 2015 Dec;40(23):4597-602

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December 2015

Anti-inflammatory effect of acetylharpagide demonstrated by its influence on leukocyte adhesion and transmigration in endothelial cells under controlled shear stress.

Clin Hemorheol Microcirc 2014 ;56(3):205-17

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.

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http://dx.doi.org/10.3233/CH-131704DOI Listing
August 2015

Establishment of an interleukin-1β-induced inflammation-activated endothelial cell-smooth muscle cell-mononuclear cell co-culture model and evaluation of the anti-inflammatory effects of tanshinone IIA on atherosclerosis.

Mol Med Rep 2015 Aug 23;12(2):1665-76. Epub 2015 Apr 23.

Department of Pharmacokinetics of Chinese Materia Medica, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, P.R. China.

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http://dx.doi.org/10.3892/mmr.2015.3668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464412PMC
August 2015

Leiomodin-3-deficient mice display nemaline myopathy with fast-myofiber atrophy.

Dis Model Mech 2015 Jun 16;8(6):635-41. Epub 2015 Apr 16.

State Key Laboratory of Genetic Engineering and National Center for International Research of Development and Disease, Fudan-Yale Center for Biomedical Research, Innovation Center for International Cooperation of Genetics and Development, Institute of Developmental Biology and Molecular Medicine, School of Life Sciences, Fudan University, Shanghai 200433, China Howard Hughes Medical Institute, Department of Genetics, Yale University School of Medicine, New Haven, CT 06536, USA

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http://dmm.biologists.org/content/dmm/8/6/635.full.pdf
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http://dmm.biologists.org/cgi/doi/10.1242/dmm.019430
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http://dx.doi.org/10.1242/dmm.019430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457035PMC
June 2015

Ligustri lucidi fructus as a traditional Chinese medicine: a review of its phytochemistry and pharmacology.

Nat Prod Res 2015 23;29(6):493-510. Epub 2014 Sep 23.

a Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences , Beijing 100700 , P.R. China.

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http://www.tandfonline.com/doi/full/10.1080/14786419.2014.95
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http://dx.doi.org/10.1080/14786419.2014.954114DOI Listing
April 2015

C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation.

J Biol Chem 2014 Oct 8;289(43):30052-62. Epub 2014 Sep 8.

From the Departments of Molecular and Cellular Oncology, and Immunology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030,

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http://dx.doi.org/10.1074/jbc.M114.588574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208012PMC
October 2014

[On plant stem cells and animal stem cells].

Zhongguo Zhong Yao Za Zhi 2014 Jan;39(2):343-5

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January 2014

In vitro and in vivo therapeutic efficacy of carfilzomib in mantle cell lymphoma: targeting the immunoproteasome.

Mol Cancer Ther 2013 Nov 29;12(11):2494-504. Epub 2013 Aug 29.

Corresponding Authors: Liang Zhang, Department of Lymphoma and Myeloma, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 0903, Houston, TX 77030.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0156DOI Listing
November 2013

C-type lectin receptors Dectin-3 and Dectin-2 form a heterodimeric pattern-recognition receptor for host defense against fungal infection.

Immunity 2013 Aug 1;39(2):324-34. Epub 2013 Aug 1.

Department of Immunology, Tongji University School of Medicine, Shanghai 200092, China.

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http://dx.doi.org/10.1016/j.immuni.2013.05.017DOI Listing
August 2013

Flowing cell trail to determine erythrocyte velocity in rat mesentery microcirculation by a consumer grade high-speed camera.

Clin Hemorheol Microcirc 2012 ;52(1):1-4

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.

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http://dx.doi.org/10.3233/CH-2012-1537DOI Listing
January 2013

[Analyses on positive influence of harmonous development of traditional Chinese medicine compounds' researchs and patent protection].

Zhongguo Zhong Yao Za Zhi 2012 Jan;37(1):9-12

Hebei Medical University, Shijiazhuang 050091, China.

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January 2012

Effects of shenlian extracts on atherosclerosis by inhibition of the inflammatory response.

J Tradit Chin Med 2011 Dec;31(4):344-8

Department of pharmacokinetics of Chinese Materia Medic, Institute of Chinese Materia Medica, China Academy of Chinese Medical sciences, Beijing, 100700 P.R. China

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December 2011

Joint preventive effects of swimming and Shenlian extract on rat atherosclerosis.

Clin Hemorheol Microcirc 2011 ;47(3):187-98

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.

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http://dx.doi.org/10.3233/CH-2010-1380DOI Listing
August 2011

[Chemical constituents from Bufonis periostracum and their antitumor activity in vitro].

Zhongguo Zhong Yao Za Zhi 2011 Aug;36(16):2207-10

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

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August 2011

Impact of tracheal mucosa involvement on clinical characteristics of sarcoidosis.

South Med J 2011 May;104(5):315-8

Department of Respiratory Medicine, Sarcoidosis Treatment Center of PLA, Navy General Hospital of PLA, Beijing City, China.

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http://dx.doi.org/10.1097/SMJ.0b013e318213ec03DOI Listing
May 2011

CARMA3 is crucial for EGFR-Induced activation of NF-κB and tumor progression.

Cancer Res 2011 Mar;71(6):2183-92

Department of Molecular and Cellular Oncology, University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059846PMC
March 2011

The mouse hairy ears mutation exhibits an extended growth (anagen) phase in hair follicles and altered Hoxc gene expression in the ears.

Vet Dermatol 2008 Dec 14;19(6):358-67. Epub 2008 Nov 14.

Mammalian Genetics and Genomics Group, Life Sciences Division, Oak Ridge National Laboratory, PO Box 2008, Bethel Valley Road, Oak Ridge, TN 37831-6445, USA.

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http://dx.doi.org/10.1111/j.1365-3164.2008.00709.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061202PMC
December 2008

Mice deficient for a small cluster of Piwi-interacting RNAs implicate Piwi-interacting RNAs in transposon control.

Biol Reprod 2008 Jul 9;79(1):51-7. Epub 2008 Apr 9.

Center for Research on Reproduction and Women's Health, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6080, USA.

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http://dx.doi.org/10.1095/biolreprod.108.068072DOI Listing
July 2008

Phosphorylation and ubiquitination of the IkappaB kinase complex by two distinct signaling pathways.

EMBO J 2007 Apr 15;26(7):1794-805. Epub 2007 Mar 15.

Department of Molecular and Cellular Oncology, University of Texas, M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/sj.emboj.7601622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847656PMC
April 2007

CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-{kappa}B activation.

Genes Dev 2007 Apr;21(8):984-96

Department of Molecular and Cellular Oncology, The University of Texas, M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1101/gad.1502507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847715PMC
April 2007

The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens.

Nat Immunol 2007 Feb 24;8(2):198-205. Epub 2006 Dec 24.

Department of Molecular and Cellular Oncology, University of Texas, M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dukespace.lib.duke.edu/dspace/bitstream/handle/10161/
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http://www.nature.com/doifinder/10.1038/ni1426
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http://dx.doi.org/10.1038/ni1426DOI Listing
February 2007

Bcl10 plays a critical role in NF-kappaB activation induced by G protein-coupled receptors.

Proc Natl Acad Sci U S A 2007 Jan 19;104(1):145-50. Epub 2006 Dec 19.

Department of Molecular and Cellular Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030 [corrected] USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0601894104
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http://dx.doi.org/10.1073/pnas.0601894104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1765424PMC
January 2007

Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation.

J Biol Chem 2006 May 16;281(19):13636-43. Epub 2006 Mar 16.

Deptartment of Molecular and Cellular Oncology, University of Texas, M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1074/jbc.M600620200DOI Listing
May 2006

X-ray-induced deletion complexes in embryonic stem cells on mouse chromosome 15.

Mamm Genome 2005 Sep 20;16(9):661-71. Epub 2005 Oct 20.

Graduate School of Genome Sciences and Technology, The University of Tennessee, Knoxville, Tennessee 37996, USA.

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http://dx.doi.org/10.1007/s00335-005-0011-5DOI Listing
September 2005

Restoration of NF-kappaB activation by tumor necrosis factor alpha receptor complex-targeted MEKK3 in receptor-interacting protein-deficient cells.

Mol Cell Biol 2004 Dec;24(24):10757-65

Department of Microbiology and Immunology, School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, 138 Farber Hall, 3435 Main St., Buffalo, NY 14214, USA.

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http://dx.doi.org/10.1128/MCB.24.24.10757-10765.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC533972PMC
December 2004

Modification of an existing chromosomal inversion to engineer a balancer for mouse chromosome 15.

Genetics 2004 Jun;167(2):889-95

Graduate School of Genome Sciences and Technology, Cellular and Molecular Biology, The University of Tennessee, Knoxville, 37996, USA.

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http://dx.doi.org/10.1534/genetics.104.026468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470889PMC
June 2004

MALT1/paracaspase is a signaling component downstream of CARMA1 and mediates T cell receptor-induced NF-kappaB activation.

J Biol Chem 2004 Apr 30;279(16):15870-6. Epub 2004 Jan 30.

Department of Microbiology and Immunology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York 14214, USA.

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http://dx.doi.org/10.1074/jbc.M310599200DOI Listing
April 2004

CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1.

Mol Cell Biol 2004 Jan;24(1):164-71

Department of Microbiology and Immunology, School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, Buffalo, New York 14214, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC303359PMC
http://dx.doi.org/10.1128/mcb.24.1.164-171.2003DOI Listing
January 2004

Overlapping deletions define novel embryonic lethal loci in the mouse t complex.

Genesis 2003 Feb;35(2):133-42

Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6445, USA.

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http://dx.doi.org/10.1002/gene.10174DOI Listing
February 2003

A requirement for CARMA1 in TCR-induced NF-kappa B activation.

Nat Immunol 2002 Sep 5;3(9):830-5. Epub 2002 Aug 5.

Department of Microbiology, School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, Buffalo, NY 14214, USA.

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http://dx.doi.org/10.1038/ni824DOI Listing
September 2002

Nuclear factor-kappa B augments beta(2)-adrenergic receptor expression in human airway epithelial cells.

Am J Physiol Lung Cell Mol Physiol 2001 Nov;281(5):L1271-8

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.

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http://dx.doi.org/10.1152/ajplung.2001.281.5.L1271DOI Listing
November 2001