Yuko Y Palesch

Yuko Y Palesch

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Yuko Y Palesch

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Blood pressure control and clinical outcomes in acute intracerebral haemorrhage: a preplanned pooled analysis of individual participant data.

Lancet Neurol 2019 Sep;18(9):857-864

The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia; Neurology Department, Royal Prince Alfred Hospital, Sydney Health Partners, Sydney, NSW, Australia; George Institute China at Peking University Health Science Center, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(19)30196-6DOI Listing
September 2019

Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.

N Engl J Med 2018 Jul 16;379(3):215-225. Epub 2018 May 16.

From the Dean's Office, Dell Medical School, University of Texas at Austin, Austin (S.C.J.); the Department of Neurology, University of California, San Francisco, San Francisco (J.D.E., M.F., A.S.K.); the Department of Emergency Medicine, University of Michigan, Ann Arbor (W.B.); the Division of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda (R.A.C.), and Emmes, Rockville (A.S.L.) - both in Maryland; and the Data Coordination Unit, Department of Public Health Sciences, Medical University of South Carolina, Charleston (J.J.E., Y.Y.P.).

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http://dx.doi.org/10.1056/NEJMoa1800410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193486PMC
July 2018

Blood Pressure-Attained Analysis of ATACH 2 Trial.

Stroke 2018 06 22;49(6):1412-1418. Epub 2018 May 22.

Department of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan (K.T., H.Y.).

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http://dx.doi.org/10.1161/STROKEAHA.117.019845DOI Listing
June 2018

Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging.

N Engl J Med 2018 02 24;378(8):708-718. Epub 2018 Jan 24.

From the Departments of Neurology and Neurological Sciences (G.W.A., S. Kemp, S.C., J.P.T., S.H., M.M., M.G.L.), Diagnostic Radiology (M.P.M., J.J.H., G.Z.), Radiology (R.B.), and Biomedical Data Science (P.W.L.), Stanford University School of Medicine, Stanford, and the Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles (M.K.-T.) - both in California; the Departments of Neurology, Anesthesia, Neurosurgery, and Radiology, University of Iowa, Ames (S.O.-G.); the Departments of Diagnostic Imaging, Neurology, and Neurosurgery, Warren Alpert School of Medicine at Brown University and Rhode Island Hospital, Providence (R.A.M.); the Departments of Neurology and Neurosurgery, Ohio State University, Columbus (M.T.T.), and the University of Cincinnati Gardner Neuroscience Institute and the Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati (J.C., J.P.B.) - both in Ohio; the Departments of Neurosurgery and Neurology, Massachusetts General Hospital, Boston (T.L.-M.); the Department of Neurology, University of Texas Health Science Center, Houston (A.S.); the Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia (S.E.K.); the Departments of Radiology, Neurology, and Neurological Surgery, Northwestern University, Feinberg School of Medicine, Chicago (S.A.A.); the Department of Public Health Sciences, Medical University of South Carolina, Charleston (S.D.Y., Y.Y.P.); the Department of Neurology, New York University School of Medicine, New York (S. Kim); and the Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary Cumming School of Medicine, Calgary, AB, Canada (A.M.D.).

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http://dx.doi.org/10.1056/NEJMoa1713973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590673PMC
February 2018

The impact of covariate misclassification using generalized linear regression under covariate-adaptive randomization.

Stat Methods Med Res 2018 01 23;27(1):20-34. Epub 2015 Nov 23.

1 Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1177/0962280215616405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476516PMC
January 2018

Assessing the impact of safety monitoring on the efficacy analysis in large Phase III group sequential trials with non-trivial safety event rate.

J Biopharm Stat 2016 26;26(4):672-85. Epub 2015 May 26.

b Department of Public Health Sciences , Medical University of South Carolina , Charleston , South Carolina , USA.

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http://dx.doi.org/10.1080/10543406.2015.1052473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661138PMC
November 2017

A surrogate-primary replacement algorithm for response-adaptive randomization in stroke clinical trials.

Stat Methods Med Res 2017 Jun 12;26(3):1078-1092. Epub 2015 Jan 12.

2 Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1177/0962280214567142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499496PMC
June 2017

Stroke Recovery and Rehabilitation Research: Issues, Opportunities, and the National Institutes of Health StrokeNet.

Stroke 2017 03 7;48(3):813-819. Epub 2017 Feb 7.

From the Departments of Neurology, Anatomy and Neurobiology (S.C.C.), and Physical Medicine and Rehabilitation (S.C.C.), and the Sue and Bill Gross Stem Cell Research Center (S.C.C.), University of California, Irvine; Division of Physical Therapy, Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA (S.L.W.); Atlanta VA Center for Visual and Neurocognitive Rehabilitation, GA (S.L.W.); Department of Neurology, University of Iowa, Iowa City (H.P.A.); Extramural Research Program, National Institute of Neurological Disorders and Stroke, Bethesda, MD (D.C.); Department of Rehabilitation Medicine, MedStar National Rehabilitation Hospital, Georgetown University, Washington, DC (A.W.D.); Washington DC VA Medical Center (A.W.D.); Department of Rehabilitation Sciences, University of Cincinnati, OH (K.D.); Data Coordination Unit, Department of Public Health Sciences, Medical University of South Carolina, Charleston (C.E., Y.Y.P.); Department of Neurosurgery, University of Minnesota, Minneapolis (A.G.); Office of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda, MD (S.J.); Department of Neurology and Neurological Sciences, Stanford Stroke Center, Stanford University School of Medicine, CA (M.G.L.); Stroke Division, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY (R.M.L.); Department of Occupational Therapy, University of Utah, Salt Lake City (L.R.); Department of Physical Medicine and Rehabilitation, Northwestern Feinberg School of Medicine, Chicago, IL (E.R.); Department of Neurology, University of Texas, Houston (S.I.S.); Department of Neurology, University of Pittsburgh Medical School, PA (L.R.W.); Neuroradiology Section, Department of Radiology, Stanford Healthcare and School of Medicine, CA (M.W.); University of Cincinnati Gardner Neuroscience Institute (J.P.B.) and Department of Neurology and Rehabilitation Medicine (J.P.B.), University of Cincinnati, OH.

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http://dx.doi.org/10.1161/STROKEAHA.116.015501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330812PMC
March 2017

Power of an Adaptive Trial Design for Endovascular Stroke Studies: Simulations Using IMS (Interventional Management of Stroke) III Data.

Stroke 2016 12 15;47(12):2931-2937. Epub 2016 Nov 15.

From the Stanford Stroke Center, School of Medicine (M.G.L., N.S.B., G.W.A.), Department of Statistics (T.L.L., P.W.L.), Department of Biomedical Data Science, School of Medicine (T.L.L., P.W.L.), Stanford University, CA; Department of Public Health Sciences, Medical University of South Carolina, Charleston (S.D.Y., Y.Y.P.); and Department of Neurology, University of Cincinnati Medical Center, OH (J.P.B.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134921PMC
December 2016

Intensive Blood-Pressure Lowering in Cerebral Hemorrhage.

N Engl J Med 2016 12;375(23):e48

Baylor College of Medicine, Houston, TX

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http://dx.doi.org/10.1056/NEJMc1613117DOI Listing
December 2016

Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.

N Engl J Med 2016 09 8;375(11):1033-43. Epub 2016 Jun 8.

From the Zeenat Qureshi Stroke Research Center, University of Minnesota, Minneapolis (A.I.Q.); the Department of Public Health Sciences, Medical University of South Carolina, Charleston (Y.Y.P., R.L.M.); the Department of Emergency Medicine, University of Michigan, Ann Arbor (W.G.B., R.S.); the Division of Brain Injury Outcomes, Johns Hopkins University, Baltimore (D.F.H.), and the Neurological Institute, National Institute of Neurological Disorders and Stroke, Bethesda (C.S.M.) - both in Maryland; China Medical University, Taichung, Taiwan (C.Y.H.); the Department of Neurology, Klinikum Frankfurt Höchst, Frankfurt, and the Department of Neurology, Heidelberg University Hospital, Heidelberg - both in Germany (T.S.); the Department of Neurology, Baylor College of Medicine, Houston (J.I.S.); the Departments of Cerebrovascular Medicine (K.T.) and Data Sciences (H.Y.), National Cerebral and Cardiovascular Center, Suita, Japan; Beijing Tiantan Hospital, Beijing (Y.W.); and the Department of Neurology, Seoul National University Hospital, Seoul, South Korea (B.-W.Y.).

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http://dx.doi.org/10.1056/NEJMoa1603460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345109PMC
September 2016

ALIAS (Albumin in Acute Ischemic Stroke) Trials: Analysis of the Combined Data From Parts 1 and 2.

Stroke 2016 09 26;47(9):2355-9. Epub 2016 Jul 26.

From the Department of Public Health Sciences, Medical University of South Carolina, Charleston (R.H.M., S.D.Y., Y.Y.P.); Calgary Stroke Program, Department of Clinical Neurosciences, Medicine, Radiology and Community Health Sciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, AB, Canada (M.D.H.); Office of Clinical Research, National Institute of Neurological Disorders and Stroke, National Institutes of health, Bethesda, MD (C.S.M.); and Department of Neurology, University of Miami Miller School of Medicine, FL (M.D.G.).

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http://dx.doi.org/10.1161/STROKEAHA.116.012825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995121PMC
September 2016

Assessing type I error and power of multistate Markov models for panel data-A simulation study.

Commun Stat Simul Comput 2017 23;46(9):7040-7061. Epub 2016 Sep 23.

Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC.

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http://dx.doi.org/10.1080/03610918.2016.1222425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722228PMC
September 2016

The National Institutes of Health StrokeNet: A User's Guide.

Stroke 2016 Feb 29;47(2):301-3. Epub 2015 Dec 29.

From the Departments of Neurology and Rehabilitation Medicine and Radiology, University of Cincinnati Neuroscience Institute, University of Cincinnati Academic Health Center, OH (J.P.B.); Department of Public Health Sciences, Medical University of South Carolina, Charleston (Y.Y.P); and the National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (L.S.J.).

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http://dx.doi.org/10.1161/STROKEAHA.115.011743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729626PMC
February 2016

Effect of endovascular reperfusion in relation to site of arterial occlusion.

Neurology 2016 Feb 22;86(8):762-70. Epub 2016 Jan 22.

From KU Leuven, University of Leuven, Belgium, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (R.L.); University Hospitals Leuven, Department of Neurology (R.L.); VIB, Vesalius Research Center, Laboratory of Neurobiology (R.L.); Stanford Stroke Center (S.A.H., M.P.M., G.W.A., M.G.L.), Stanford University of Medicine, CA; Neurovascular Imaging Research Core and Department of Neurology and Comprehensive Stroke Center (D.S.L., J.L.S.), and Division of Interventional Neuroradiology, Department of Radiology, David Geffen School of Medicine (R.J.), University of California, Los Angeles; Departments of Radiology (T.A.T.) and Neurology (J.P.B.), University of Cincinnati Medical Center, OH; Departments of Clinical Neurosciences and Radiology (A.M.D.), Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Canada; Departments of Neurology, Neurosurgery, and Radiology (R.G.N.), Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA; Department of Diagnostic and Interventional Neuroradiology (J.G.), University Hospital Bern, Switzerland; Division of Diagnostic and Interventional Neuroradiology (A.J.Y.), Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston; Department of Public Health Sciences (S.D.Y., Y.Y.P.), Medical University of South Carolina, Charleston; and Division of Neuroradiology, Department of Medical Imaging, and Division of Neurosurgery, Department of Surgery (V.M.P.), Toronto Western Hospital, University Health Network, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000002399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763803PMC
February 2016

Endovascular Therapy Is Effective and Safe for Patients With Severe Ischemic Stroke: Pooled Analysis of Interventional Management of Stroke III and Multicenter Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke in the Netherlands Data.

Stroke 2015 Dec 20;46(12):3416-22. Epub 2015 Oct 20.

From the Departments of Neurology and Rehabilitation Medicine and Radiology, University of Cincinnati Neuroscience Institute, University of Cincinnati Academic Health Center, Cincinnati, OH (J.P.B., P.K., J.S., J.C., T.A.T.); Division of Emergency Medicine (E.C.J.), Department of Public Health Sciences (Y.Y.P., L.D.F.), and Department of Healthcare Management and Leadership (K.N.S.), Medical University of South Carolina, Charleston; Calgary Stroke Program, Seaman Family MR Research Centre, Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada (A.M.D., M.D.H., M.G., K.J.R.); the Stroke Institute, University of Pittsburgh Medical Center, PA (T.G.J.); Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria, Australia (B.Y.); Department of Neuroradiology, Dresden University Stroke Center, University Hospital, Dresden, Germany (R.v.K.); Neurovascular Unit, Department of Neurology, Hospital Universitari Vall d'Hebron, Barcelona, Spain (C.A.M.); Department of Neurology, University Medical Center Utrecht and the Rudolph Magnus Institute of Neurosciences, Utrecht, the Netherlands (W.J.S.); St. Antonius Hospital, Nieuwegein, the Netherlands (W.J.S.); Department of Neurology and Stroke Center, Lariboisière Hospital, Paris, France (M.M.); Department of Neurology, Basel University Hospital, Basel, Switzerland (S.T.E.); the George Institute for Global Health, Royal Prince Alfred Hospital, University of Sydney, Sydney (C.S.A.); and the National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (L.S.J.); the Department of Radiology (O.A.B., C.B.L.M.M.) and Neurology (Y.B.W.E.M.R.), Academic Medical Center, Amsterdam, the Netherlands; Department of Neurology (D.W.J.D., B.R.), Radiology (A.v.d.L.), and Public Health (H.F.L.), Erasmus MC University Medical Center, Rotterdam, Netherlands; and Department of Radiology (W.H.v.Z.) and N

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http://dx.doi.org/10.1161/STROKEAHA.115.011397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659737PMC
December 2015

Imaging in StrokeNet: Realizing the Potential of Big Data.

Stroke 2015 Jul 4;46(7):2000-6. Epub 2015 Jun 4.

From the Neurovascular Imaging Research Core (D.S.L.) and Department of Neurology, Comprehensive Stroke Center, Geffen School of Medicine (D.S.L., J.L.S.), University of California, Los Angeles; Departments of Neurology (G.W.A.) and Radiology (M.W.), Stanford University, Palo Alto, CA; Laboratory of Neuro Imaging, Institute for Neuroimaging and Informatics, Keck School of Medicine, University of Southern California, Los Angeles (K.C., A.W.T.); Departments of Neurology and Neurological Surgery, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO (C.P.D.); Departments of Psychiatry, Radiology, and Neuroscience (M.S.G.) and Public Health Sciences (Y.Y.P., W.Z.), Medical University of South Carolina, Charleston; Ralph H Johnson VA Medical Center, Charleston, SC (M.S.G.); University of Texas Southwestern Medical Center, Austin (S.W.); Department of Neurology, Mayo Clinic, Jacksonville, FL (T.G.B.); Departments of Neurology, Public Health Sciences, Human Genetics, and Neurosurgery, Miller School of Medicine, University of Miami, FL (R.L.S.); Department of Neurology, University of Cincinnati, OH (P.K., J.P.B.); Department of Neurology, University of California, Irvine (S.C.C.); and Department of Rehabilitation Medicine, Emory University School of Medicine and Center for Visual and Cognitive Neurorehabilitation, Atlanta VA Medical Center, GA (S.L.W.).

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http://stroke.ahajournals.org/lookup/doi/10.1161/STROKEAHA.1
Publisher Site
http://dx.doi.org/10.1161/STROKEAHA.115.009479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557967PMC
July 2015

Multi-modality neuro-monitoring: conventional clinical trial design.

Neurocrit Care 2015 Jun;22(3):369-77

Division of Neurocritical Care and Vascular Neurology, Department of Neurology, Baylor College of Medicine, 6501 Fannin Street, MS: NB320, Houston, TX, 77030, USA,

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http://dx.doi.org/10.1007/s12028-015-0134-9DOI Listing
June 2015

Twelve-Month Clinical and Quality-of-Life Outcomes in the Interventional Management of Stroke III Trial.

Stroke 2015 May 9;46(5):1321-7. Epub 2015 Apr 9.

From the Departments of Neurology and Rehabilitation Medicine and Radiology, University of Cincinnati Neuroscience Institute, University of Cincinnati Academic Health Center, Cincinnati (J.P.B., P.K., J.S., J.C., T.A.T.); Department of Public Health Sciences (Y.Y.P., S.D.Y., L.D.F., A.S., K.N.S.) and Division of Emergency Medicine (E.C.J.), Medical University of South Carolina, Charleston; Calgary Stroke Program, Seaman Family MR Research Centre, Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada (A.M.D., M.D.H., M.G., K.J.R.); Stroke Institute, University of Pittsburgh Medical Center, Pittsburgh (T.G.J.); Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia (B.Y.); Department of Neuroradiology, Dresden University Stroke Center, University Hospital, Dresden, Germany (R.v.K.); Neurovascular Unit, Department of Neurology, Hospital Universitari Vall d'Hebron, Barcelona (C.A.M.); Department of Neurology, University Medical Center Utrecht and the Rudolph Magnus Institute of Neurosciences, Utrecht, the Netherlands, and the St. Antonius Hospital, Nieuwegein, the Netherlands (W.J.S.); Department of Neurology and Stroke Center, Lariboisière Hospital, Paris (M.M.); Department of Neurology, Basel University Hospital, Basel, Switzerland (S.T.E.); George Institute for Global Health, Royal Prince Alfred Hospital, University of Sydney, Sydney (C.A.); and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (L.S.J.).

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http://dx.doi.org/10.1161/STROKEAHA.115.009180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414900PMC
May 2015

Measuring continuous baseline covariate imbalances in clinical trial data.

Stat Methods Med Res 2015 Apr 24;24(2):255-72. Epub 2011 Aug 24.

Division of Biostatistics and Epidemiology, 135 Cannon Street, Suite 303, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1177/0962280211416038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280338PMC
April 2015

Evolution of practice during the Interventional Management of Stroke III Trial and implications for ongoing trials.

Stroke 2014 Dec 16;45(12):3606-11. Epub 2014 Oct 16.

From the Departments of Neurology and Rehabilitation Medicine and Radiology, University of Cincinnati Neuroscience Institute, University of Cincinnati Academic Health Center, Cincinnati (J.P.B., P.K., J.S., J.C., T.A.T.); Department of Public Health Sciences (Y.Y.P, S.D.Y., L.D.F.) and the Division of Emergency Medicine (E.C.J.), Medical University of South Carolina, Charleston; Calgary Stroke Program, Seaman Family MR Research Centre, Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada (A.M.D., M.D.H., M.G.); Stroke Institute, University of Pittsburgh Medical Center, Pittsburgh (T.G.J.); Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia (B.Y.); Department of Neuroradiology, Dresden University Stroke Center, University Hospital, Dresden, Germany (R.v.K.); Neurovascular Unit, Department of Neurology, Hospital Universitari Vall d'Hebron, Barcelona (C.A.M.); Department of Neurology, University Medical Center Utrecht and the Rudolph Magnus Institute of Neurosciences, Utrecht, the Netherlands, and the St. Antonius Hospital, Nieuwegein, the Netherlands (W.J.S.); Department of Neurology and Stroke Center, Lariboisière Hospital, Paris (M.M.); Department of Neurology, Basel University Hospital, Basel, Switzerland (S.T.E.); George Institute for Global Health, Royal Prince Alfred Hospital, University of Sydney, Sydney (C.A.); and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (L.S.J.).

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http://dx.doi.org/10.1161/STROKEAHA.114.005952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679363PMC
December 2014

Some common misperceptions about P values.

Authors:
Yuko Y Palesch

Stroke 2014 Dec 6;45(12):e244-6. Epub 2014 Nov 6.

From the Department of Public Health Sciences, Medical University of South Carolina, Charleston.

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http://dx.doi.org/10.1161/STROKEAHA.114.006138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245357PMC
December 2014

Very early administration of progesterone for acute traumatic brain injury.

N Engl J Med 2014 Dec 10;371(26):2457-66. Epub 2014 Dec 10.

From the Departments of Emergency Medicine (D.W.W., H.H.-S.) and Neurology (M.F., F.C.G.), Emory University School of Medicine and Grady Memorial Hospital, and the Department of Biostatistics, Rollins School of Public Health, Emory University (V.S.H.) - all in Atlanta; the Department of Public Health Sciences, Medical University of South Carolina, Charleston (S.D.Y., Y.Y.P.); the Departments of Emergency Medicine (R.S., E.M.B., W.G.B.) and Psychiatry (A.F.C.), University of Michigan, Ann Arbor; the Department of Neurosurgery, University of California, San Francisco, San Francisco (G.T.M.); the Department of Emergency Medicine, Warren Alpert Medical School of Brown University, Providence, RI (L.H.M.); and the National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (L.S.J.).

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http://www.epilepsyfoundationmn.org/files/8714/2109/3372/Pro
Web Search
http://www.nejm.org/doi/abs/10.1056/NEJMoa1404304
Publisher Site
http://dx.doi.org/10.1056/NEJMoa1404304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303469PMC
December 2014

Recanalization and clinical outcome of occlusion sites at baseline CT angiography in the Interventional Management of Stroke III trial.

Radiology 2014 Oct 5;273(1):202-10. Epub 2014 Jun 5.

From the Calgary Stroke Program, Dept of Clinical Neurosciences and Radiology, Hotchkiss Brain Inst, Univ of Calgary, 1403 29 St NW, Room 112, Calgary, AB, Canada T2N 2T9 (A.M.D., M.G., E.Q., M.D.H.); Dept of Public Health Sciences, Medical Univ of South Carolina, Charleston, SC (S.D.Y., L.D.F., Y.Y.P.); Depts of Neurology and Rehabilitation Medicine and Radiology, Univ of Cincinnati Academic Health Ctr, Cincinnati, Ohio (J.C., P.K., T.A.T., J.P.B.); Stroke Inst, Univ of Pittsburgh Medical Ctr, Pittsburgh, Pa (T.G.J.); Neurovascular Unit, Dept of Neurology, Hosp Universitari Vall d'Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain (M.R.); Melbourne Brain Ctr, The Royal Melbourne Hosp, Univ of Melbourne, Australia (B.Y.); Dept of Radiology, Medical College of Wisconsin, Milwaukee, Wis (O.O.Z.); Colorado Neurologic Inst, Denver, Colo (D.F.); Dept of Neuroradiology, Dresden Univ Stroke Ctr, Univ Hosp, Dresden, Germany (R.v.K.); Dept of Neurosurgery, Radiology and Public Health Sciences, Penn State M.S. Hershey Medical Ctr, Hershey, Pa (K.C.); and UCLA Stroke Ctr, Los Angeles, Calif (D.S.L.).

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http://pubs.rsna.org/doi/10.1148/radiol.14132649
Publisher Site
http://dx.doi.org/10.1148/radiol.14132649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174723PMC
October 2014

Drivers of costs associated with reperfusion therapy in acute stroke: the Interventional Management of Stroke III Trial.

Stroke 2014 Jun 13;45(6):1791-8. Epub 2014 May 13.

From the Department of Neurology and Rehabilitation Medicine, University of Cincinnati Academic Health Center, OH (J.P.B., D.K., P.K., J.A.S.); Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada (M.D.H.); and Department of Healthcare Leadership and Management (K.N.S., A.N.S.), Department of General Internal Medicine (P.D.M.), Department of Public Health Sciences (S.D.Y., L.D.F., R.M., Y.Y.P.), Department of Emergency Medicine (E.C.J.), Medical University of South Carolina, Charleston.

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http://dx.doi.org/10.1161/STROKEAHA.113.003874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128893PMC
June 2014

Continuous covariate imbalance and conditional power for clinical trial interim analyses.

Contemp Clin Trials 2014 May 7;38(1):9-18. Epub 2014 Mar 7.

Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1016/j.cct.2014.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024327PMC
May 2014

Challenges of decision making regarding futility in a randomized trial: the Interventional Management of Stroke III experience.

Stroke 2014 May 3;45(5):1408-14. Epub 2014 Apr 3.

From the Data Coordination Unit, Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC (S.D.Y., R.H.M., L.D.F., R.F.W., Y.Y.P.); Department of Biostatistics, University of Iowa, Iowa City, IA (C.S.C.); Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA (P.D.L.); Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH (J.P.B.); Department of Medicine, Division of Cardiology, Columbia University Medical Center, New York, NY (M.R.D.T); and Department of Radiology, Temple University School of Medicine, Philadelphia, PA (C.A.J.).

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http://stroke.ahajournals.org/cgi/doi/10.1161/STROKEAHA.113.
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May 2014

Collaterals at angiography and outcomes in the Interventional Management of Stroke (IMS) III trial.

Stroke 2014 Mar 28;45(3):759-64. Epub 2014 Jan 28.

From UCLA Stroke Center, Los Angeles, CA (D.S.L.); University of Cincinnati, Cincinnati, OH (T.A.T., J.C., P.K., J.P.B.); Medical University of South Carolina, Charleston, SC (L.D.F., S.D.Y., Y.Y.P.); Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada (A.M.D., M.G., B.K.M.); UPMC Stroke Institute, Pittsburgh, PA (T.G.J.); Department of Neuroradiology, University of Dresden, Dresden, Germany (R.v.K.); University of Mississippi, Jackson, MS (R.M.S.); Medical College of Wisconsin/Froedtert Hospital, Milwaukee, WI (O.O.Z.); Michigan State University, East Lansing, MI (S.I.H.); Summit Neurovascular Specialties and Akron General Hospital, Akron, OH (F.A.A.); and Royal Melbourne Hospital, Parkville, Victoria, Australia (B.Y.).

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March 2014

[Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH)-II at Japan site: study design and advance construction of domestic research network].

Rinsho Shinkeigaku 2012 ;52(9):642-50

Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center.

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December 2013

High dose deferoxamine in intracerebral hemorrhage (HI-DEF) trial: rationale, design, and methods.

Neurocrit Care 2013 Oct;19(2):257-66

Data Coordination Unit, Department of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, SC, USA.

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October 2013

Endovascular treatment for acute ischemic stroke.

N Engl J Med 2013 06;368(25):2432-3

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June 2013

Subject-investigator reproducibility of the Unified Parkinson's Disease Rating Scale.

Parkinsonism Relat Disord 2012 Mar 21;18(3):230-3. Epub 2011 Oct 21.

Division of Biostatistics & Epidemiology, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288816PMC
March 2012

The Albumin in Acute Stroke Part 1 Trial: an exploratory efficacy analysis.

Stroke 2011 Jun 5;42(6):1621-5. Epub 2011 May 5.

Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Foothills Hospital, Room 1242A, 1403 29th St. NW, Calgary, Alberta, T2N 2T9, Canada.

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June 2011

Design and analysis plans.

Authors:
Yuko Y Palesch

Front Neurol Neurosci 2009 19;25:76-77. Epub 2009 Mar 19.

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July 2009

Design of the economic evaluation for the Interventional Management of Stroke (III) trial.

Int J Stroke 2008 May;3(2):138-44

Department of Pharmacy and Clinical Sciences, Medical University of South Carolina, Ralph H Johnson VA Medical Center, Charleston, SC 29425, USA.

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May 2008

Comments regarding the recent OAST article.

Stroke 2008 Jan 29;39(1):e14; author reply e15. Epub 2007 Nov 29.

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January 2008

The albumin in acute stroke trial (ALIAS); design and methodology.

Int J Stroke 2007 Aug;2(3):214-9

Department of Clinical Neurosciences, Calgary Stroke Program, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.

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August 2007

The ALIAS Pilot Trial: a dose-escalation and safety study of albumin therapy for acute ischemic stroke--II: neurologic outcome and efficacy analysis.

Stroke 2006 Aug 29;37(8):2107-14. Epub 2006 Jun 29.

Department of Neurology (D4-5), University of Miami Miller School of Medicine, PO Box 016960, Miami, Florida 33101, USA.

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August 2006

The ALIAS Pilot Trial: a dose-escalation and safety study of albumin therapy for acute ischemic stroke--I: Physiological responses and safety results.

Stroke 2006 Aug 29;37(8):2100-6. Epub 2006 Jun 29.

Department of Neurology (D4-5), University of Miami Miller School of Medicine, PO Box 016960, Miami, Florida 33101, USA.

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August 2006

Non-linearity of Parkinson's disease progression: implications for sample size calculations in clinical trials.

Clin Trials 2005 ;2(6):509-18

Dept of Biostatistics, Bioinformatics & Epidemiology, Medical University of South Carolina, 135 Cannon St. Suite 303, Charleston, SC 29425, USA.

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March 2006

Applying a phase II futility study design to therapeutic stroke trials.

Stroke 2005 Nov 13;36(11):2410-4. Epub 2005 Oct 13.

Department of Biostatistics, Bioinformatics & Epidemiology, Medical University of South Carolina, P.O. Box 250835, Charleston, SC 29425, USA.

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November 2005

A responsive outcome for Parkinson's disease neuroprotection futility studies.

Ann Neurol 2005 Feb;57(2):197-203

Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, Charleston, SC 29425, USA.

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February 2005

An efficient multi-stage, single-arm Phase II futility design for ALS.

Amyotroph Lateral Scler Other Motor Neuron Disord 2004 Sep;5 Suppl 1:55-6

Medical University of South Carolina, Charleston, SC, USA.

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September 2004

Alzheimer's Disease in the Family Practice Setting: Assessment of a Screening Tool.

Prim Care Companion J Clin Psychiatry 2004 ;6(6):234-238

Department of Biometry and Epidemiology and the Institute of Psychiatry , Medical University of South Carolina, Charleston; the Partnership & Support Network, Mt. Olivet Rolling Acres, Victoria, Minn. ; and The Clinical Innovation Group, MUSC Foundation for Research Development, Charleston, S.C. .

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January 2004

Analysis of clustered matched-pair data.

Stat Med 2003 Aug;22(15):2417-28

The Clinical Innovation Group (TCIG), Medical University of South Carolina, Foundation for Research Development, Charleston, SC 29401, USA.

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August 2003

Analysis of clustered matched-pair data for a non-inferiority study design.

Stat Med 2003 Jan;22(2):279-90

TCIG*STATS, The Clinical Innovation Group, MUSC Foundation for Research Development, Charleston, SC, USA.

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January 2003

The virtual colonoscopy study: a large multicenter clinical trial designed to compare two diagnostic screening procedures.

Control Clin Trials 2002 Oct;23(5):570-83

TCIG*STATS, The Clinical Innovation Group, MUSC Foundation for Research and Development, The Medical University of South Carolina, Charleston, SC, USA.

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October 2002