Yuko Hirota

Yuko Hirota

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Yuko Hirota

Yuko Hirota

Publications by authors named "Yuko Hirota"

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28Publications

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Pedunculated signet ring cell carcinoma of the stomach mimicking a hyperplastic polyp.

Gastrointest Endosc 2019 11 6;90(5):848-849. Epub 2019 Jul 6.

Digestive Disease Center, Showa University Koto Toyosu Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.gie.2019.07.003DOI Listing
November 2019

The clinical impact of MRI screening for BRCA mutation carriers: the first report in Japan.

Breast Cancer 2019 Sep 28;26(5):552-561. Epub 2019 Feb 28.

Department of Radiology, Division of Radiology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, Japan.

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http://dx.doi.org/10.1007/s12282-019-00955-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694035PMC
September 2019

Investigation of the Endoplasmic Reticulum Localization of UDP-Glucuronosyltransferase 2B7 with Systematic Deletion Mutants.

Mol Pharmacol 2019 05 3;95(5):551-562. Epub 2019 Apr 3.

Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences (Y.M., A.K., K.K., Y.H., K.F., Y.T.) and Laboratory of Molecular Life Sciences, Graduate School of Pharmaceutical Sciences (Y.M., S.K., Y.I.), Kyushu University, Fukuoka, Japan; and Department of Clinical Pharmacology, Flinders Medical Centre and Flinders University, Adelaide, South Australia, Australia (P.I.M.)

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http://dx.doi.org/10.1124/mol.118.113902DOI Listing
May 2019

Raman spectroscopy for the diagnosis of unlabeled and unstained histopathological tissue specimens.

World J Gastrointest Oncol 2018 Nov;10(11):439-448

Digestive Disease Center, Showa University Koto Toyosu Hospital, Koto-ku, Tokyo 1358577, Japan.

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http://dx.doi.org/10.4251/wjgo.v10.i11.439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247109PMC
November 2018

The association between p16 and Ki-67 immunohistostaining and the progression of cervical intraepithelial neoplasia grade 2.

Int J Gynaecol Obstet 2016 Jul 8;134(1):45-8. Epub 2016 Apr 8.

Department of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.ijgo.2015.12.005DOI Listing
July 2016

Cytology of low-grade cribriform cystadenocarcinoma in salivary glands: Cytological and immunohistochemical distinctions from other salivary gland neoplasms.

Diagn Cytopathol 2016 Mar 21;44(3):241-5. Epub 2015 Dec 21.

Department of Pathology, Clinico-Diagnostic Pathology, Showa University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1002/dc.23411DOI Listing
March 2016

Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways.

Autophagy 2015 ;11(2):332-43

a Laboratory of Biosignaling ; Niigata University Graduate School of Medical and Dental Sciences ; Niigata , Japan.

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http://dx.doi.org/10.1080/15548627.2015.1023047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502654PMC
January 2016

Intracellular Dynamics and Fate of a Humanized Anti-Interleukin-6 Receptor Monoclonal Antibody, Tocilizumab.

Mol Pharmacol 2015 Oct 15;88(4):660-75. Epub 2015 Jul 15.

Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences (K.F., H.I., Y.H., Y.T.), and Organelle Homeostasis Research Center (K.F., Y.T.), Kyushu University, Maidashi, Fukuoka, Japan; and Chugai Pharmaceutical Co., Ltd., Fuji-Gotemba Research Laboratories, Komakado, Gotemba-shi, Shizuoka, Japan (M.I., J.A.)

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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.115.09
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http://dx.doi.org/10.1124/mol.115.099184DOI Listing
October 2015

Tor and the Sin3-Rpd3 complex regulate expression of the mitophagy receptor protein Atg32 in yeast.

J Cell Sci 2014 Jul 16;127(Pt 14):3184-96. Epub 2014 May 16.

Laboratory of Biosignaling, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan

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http://dx.doi.org/10.1242/jcs.153254DOI Listing
July 2014

Age-related disruption of autophagy in dermal fibroblasts modulates extracellular matrix components.

Biochem Biophys Res Commun 2014 Jan 25;443(1):167-72. Epub 2013 Nov 25.

Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan; Organelle Homeostasis Research Center, Kyushu University, Fukuoka, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2013.11.066DOI Listing
January 2014

Casein kinase 2 is essential for mitophagy.

EMBO Rep 2013 Sep 30;14(9):788-94. Epub 2013 Jul 30.

Laboratory of Biosignaling, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510.

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http://dx.doi.org/10.1038/embor.2013.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790056PMC
September 2013

The physiological role of mitophagy: new insights into phosphorylation events.

Int J Cell Biol 2012 7;2012:354914. Epub 2012 Mar 7.

Department of Clinical Chemistry and Laboratory Medicine, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1155/2012/354914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312226PMC
August 2012

Phosphorylation of Serine 114 on Atg32 mediates mitophagy.

Mol Biol Cell 2011 Sep 14;22(17):3206-17. Epub 2011 Jul 14.

Department of Clinical Chemistry and Laboratory Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1091/mbc.E11-02-0145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164466PMC
September 2011

Suppression of oral tolerance by Lactococcus lactis in mice.

Biosci Biotechnol Biochem 2011 7;75(3):599-601. Epub 2011 Mar 7.

Department of Public Health and Applied Nutrition, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan.

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http://dx.doi.org/10.1271/bbb.100714DOI Listing
August 2011

[Mitophagy: selective degradation of mitochondria by autophagy].

Seikagaku 2011 Feb;83(2):126-30

Department of Clinical Chemistry and Laboratory Medicine, Kyushu University Graduate School of Medical Sciences, 3-1-1, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

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February 2011

Nedd4-interacting protein 2, a short half-life membrane protein degraded in lysosomes, negatively controls down-regulation of connexin43.

Biol Pharm Bull 2010 ;33(6):951-7

Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1248/bpb.33.951DOI Listing
January 2011

Antigen-dependent internalization is related to rapid elimination from plasma of humanized anti-HM1.24 monoclonal antibody.

Drug Metab Dispos 2010 Dec 7;38(12):2339-46. Epub 2010 Sep 7.

Chugai Pharmaceutical Co., Ltd., Fuji-Gotenba Research Laboratories, 1-135 Komakado, Gotenba-shi, Shizuoka 412-8513, Japan.

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http://dmd.aspetjournals.org/cgi/doi/10.1124/dmd.110.035709
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http://dx.doi.org/10.1124/dmd.110.035709DOI Listing
December 2010

A small GTPase, human Rab32, is required for the formation of autophagic vacuoles under basal conditions.

Cell Mol Life Sci 2009 Sep 11;66(17):2913-32. Epub 2009 Jul 11.

Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka 812-8582, Japan.

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http://link.springer.com/10.1007/s00018-009-0080-9
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http://dx.doi.org/10.1007/s00018-009-0080-9DOI Listing
September 2009

HM1.24 is internalized from lipid rafts by clathrin-mediated endocytosis through interaction with alpha-adaptin.

J Biol Chem 2009 Jun 8;284(23):15927-41. Epub 2009 Apr 8.

Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1074/jbc.M109.005124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708888PMC
June 2009

Drug-induced phospholipidosis is caused by blockade of mannose 6-phosphate receptor-mediated targeting of lysosomal enzymes.

Biochem Biophys Res Commun 2008 Dec 7;377(1):268-74. Epub 2008 Oct 7.

Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0801916
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http://dx.doi.org/10.1016/j.bbrc.2008.09.121DOI Listing
December 2008

A role for Rab5 activity in the biogenesis of endosomal and lysosomal compartments.

Biochem Biophys Res Commun 2007 Dec 1;364(1):40-7. Epub 2007 Oct 1.

Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka 812-8582, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0702084
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http://dx.doi.org/10.1016/j.bbrc.2007.09.089DOI Listing
December 2007

The NH(2)-terminal transmembrane and lumenal domains of LGP85 are needed for the formation of enlarged endosomes/lysosomes.

Traffic 2005 Oct;6(10):895-906

Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1111/j.1600-0854.2005.00325.xDOI Listing
October 2005

3-Methyladenine specifically inhibits retrograde transport of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor from the early endosome to the TGN.

Biochem Biophys Res Commun 2004 Apr;316(3):845-52

Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2004.02.119DOI Listing
April 2004

Analysis of post-lysosomal compartments.

Biochem Biophys Res Commun 2004 Feb;314(2):306-12

Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, 812-8582 Fukuoka, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2003.12.092DOI Listing
February 2004

Preservation of mitochondrial function during ischemia as a possible mechanism for cardioprotection of diltiazem against ischemia/reperfusion injury.

Biochem Pharmacol 2004 Feb;67(3):565-74

Department of Pharmacology, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.

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http://dx.doi.org/10.1016/j.bcp.2003.09.016DOI Listing
February 2004