Yukio Nakamura

Yukio Nakamura

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Yukio Nakamura

Publications by authors named "Yukio Nakamura"

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Unexpected rapid increase in bone mineral density by bisphosphonate therapy after multiple spinal fractures: a case report.

J Med Case Rep 2019 Sep 13;13(1):288. Epub 2019 Sep 13.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto, 390-8621, Japan.

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http://dx.doi.org/10.1186/s13256-019-2219-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743166PMC
September 2019

Efficacy of 4-year denosumab treatment alone or in combination with teriparatide in Japanese postmenopausal osteoporotic women.

Mod Rheumatol 2019 Jul 28;29(4):676-681. Epub 2018 Nov 28.

a Department of Orthopaedic Surgery , Shinshu University School of Medicine , Matsumoto , Japan.

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https://www.tandfonline.com/doi/full/10.1080/14397595.2018.1
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http://dx.doi.org/10.1080/14397595.2018.1524997DOI Listing
July 2019

Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation.

Nature 2019 07 29;571(7763):117-121. Epub 2019 May 29.

Division of Stem Cell Therapy, Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/s41586-019-1244-xDOI Listing
July 2019

Author Correction: Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation.

Nature 2019 Jul;571(7766):E12

Division of Stem Cell Therapy, Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/s41586-019-1395-9DOI Listing
July 2019

Human erythroblasts with c-Kit activating mutations have reduced cell culture costs and remain capable of terminal maturation.

Exp Hematol 2019 Jun 18;74:19-24.e4. Epub 2019 Apr 18.

Center for Pediatric Biomedical Research, Department of Pediatrics, University of Rochester, Rochester, NY. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0301472X193013
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http://dx.doi.org/10.1016/j.exphem.2019.04.001DOI Listing
June 2019

The Shisa3 knockout mouse exhibits normal bone phenotype.

J Bone Miner Metab 2019 Jun 20. Epub 2019 Jun 20.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.

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http://dx.doi.org/10.1007/s00774-019-01014-yDOI Listing
June 2019

Additive effects of eldecalcitol in poorly responding long-term bisphosphonate treatment for osteoporosis.

Osteoporos Sarcopenia 2019 Jun 28;5(2):57-61. Epub 2019 Jun 28.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

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http://dx.doi.org/10.1016/j.afos.2019.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630044PMC
June 2019

Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I.

Stem Cell Res 2019 Apr 12;36:101406. Epub 2019 Feb 12.

iPSC-based Drug Discovery and Development Team, RIKEN BioResource Research Center, Kyoto, Japan; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2019.101406DOI Listing
April 2019

A natural regulatory mutation in the proximal promoter elevates fetal expression by creating a de novo GATA1 site.

Blood 2019 Feb 7;133(8):852-856. Epub 2019 Jan 7.

School of Biotechnology and Biomolecular Sciences, University of New South Wales (UNSW Sydney), Sydney, NSW, Australia.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2018-07
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http://dx.doi.org/10.1182/blood-2018-07-863951DOI Listing
February 2019

Potential application of cell reprogramming techniques for cancer research.

Cell Mol Life Sci 2019 Jan 3;76(1):45-65. Epub 2018 Oct 3.

Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, 807, Taiwan.

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http://link.springer.com/10.1007/s00018-018-2924-7
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http://dx.doi.org/10.1007/s00018-018-2924-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326983PMC
January 2019

Establishment and characterization of immortalized erythroid progenitor cell lines derived from a common cell source.

Exp Hematol 2019 01 13;69:11-16. Epub 2018 Oct 13.

Department of Research and Development, Central Blood Institute, Blood Service Headquarters, Japanese Red Cross Society, Tokyo, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S0301472X183086
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http://dx.doi.org/10.1016/j.exphem.2018.10.005DOI Listing
January 2019

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

Genes Dev 2018 12 21;32(23-24):1537-1549. Epub 2018 Nov 21.

Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1101/gad.318436.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295165PMC
December 2018

Calcium and vitamin D supplementation with 3-year denosumab treatment is beneficial to enhance bone mineral density in postmenopausal patients with osteoporosis and rheumatoid arthritis.

Ther Clin Risk Manag 2019 18;15:15-22. Epub 2018 Dec 18.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan,

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http://dx.doi.org/10.2147/TCRM.S182858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302805PMC
December 2018

Application of immortalized human erythroid progenitor cell line in serologic tests to detect red blood cell alloantibodies.

Transfusion 2018 11 4;58(11):2675-2682. Epub 2018 Sep 4.

Department of Research and Development, Central Blood Institute, Blood Service Headquarters, Japanese Red Cross Society, Tokyo, Japan.

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http://doi.wiley.com/10.1111/trf.14840
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http://dx.doi.org/10.1111/trf.14840DOI Listing
November 2018

Olfactomedin-like protein OLFML1 inhibits Hippo signaling and mineralization in osteoblasts.

Biochem Biophys Res Commun 2018 10 25;505(2):419-425. Epub 2018 Sep 25.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X183203
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http://dx.doi.org/10.1016/j.bbrc.2018.09.112DOI Listing
October 2018

Long non-coding RNA-dependent mechanism to regulate heme biosynthesis and erythrocyte development.

Nat Commun 2018 10 22;9(1):4386. Epub 2018 Oct 22.

State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, China.

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http://www.nature.com/articles/s41467-018-06883-x
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http://dx.doi.org/10.1038/s41467-018-06883-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197277PMC
October 2018

Significant improvement of bone mineral density by denosumab without bisphosphonate pre-treatment in glucocorticoid-induced osteoporosis.

Mod Rheumatol 2018 Sep 22;28(5):885-889. Epub 2018 Jan 22.

a Department of Orthopaedic Surgery , Shinshu University School of Medicine , Nagano , Japan.

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https://www.tandfonline.com/doi/full/10.1080/14397595.2017.1
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http://dx.doi.org/10.1080/14397595.2017.1416919DOI Listing
September 2018

Establishment of a cell model of X-linked sideroblastic anemia using genome editing.

Exp Hematol 2018 09 13;65:57-68.e2. Epub 2018 Jun 13.

Department of Molecular Biochemistry, Iwate Medical University School of Medicine, Yahaba, Iwate, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2018.06.002DOI Listing
September 2018

Determination of serum bone-related minerals during denosumab treatment in osteoporosis patients with rheumatoid arthritis: Mineral change by denosumab in osteoporosis with rheumatoid arthritis.

Clin Nutr ESPEN 2018 08;26:53-56

Department of Orthopedic Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto, 390-8621, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.clnesp.2018.04.014DOI Listing
August 2018

Denosumab significantly improves lumbar spine bone mineral density more in treatment-naïve than in long-term bisphosphonate-treated patients.

Bone Rep 2018 Jun 17;8:110-114. Epub 2018 Mar 17.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto 390-8621, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S23521872183001
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http://dx.doi.org/10.1016/j.bonr.2018.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020116PMC
June 2018

Tofacitinib Versus Non-Tumor Necrosis Factor Biologics for Patients With Active Rheumatoid Arthritis.

Arch Rheumatol 2018 Jun 13;33(2):154-159. Epub 2017 Oct 13.

Department of Orthopaedic Surgery, Shinshu University, Matsumoto, Japan.

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https://www.archivesofrheumatology.org/full-text/914
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http://dx.doi.org/10.5606/ArchRheumatol.2018.6366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117139PMC
June 2018

Efficacy, safety, and compliance of ibandronate treatment for 3 years in postmenopausal Japanese women with primary osteoporosis.

Osteoporos Sarcopenia 2018 Jun 27;4(2):69-72. Epub 2018 Apr 27.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.

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http://dx.doi.org/10.1016/j.afos.2018.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362971PMC
June 2018

Efficacy of denosumab in two cases with multiple-system atrophy and osteoporosis.

Ther Clin Risk Manag 2018 3;14:817-822. Epub 2018 May 3.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

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http://dx.doi.org/10.2147/TCRM.S162574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939903PMC
May 2018

Adequate nutrition status important for bone mineral density improvement in a patient with anorexia nervosa.

Ther Clin Risk Manag 2018 18;14:945-948. Epub 2018 May 18.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

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https://www.dovepress.com/adequate-nutrition-status-importan
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http://dx.doi.org/10.2147/TCRM.S160280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965386PMC
May 2018

Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.

Cell 2018 04 29;173(2):430-442.e17. Epub 2018 Mar 29.

Cancer and Blood Disorders Center, Dana Farber Cancer Institute and Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; Howard Hughes Medical Institute, Boston, MA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183029
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http://dx.doi.org/10.1016/j.cell.2018.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889339PMC
April 2018

Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding.

Nat Genet 2018 04 2;50(4):498-503. Epub 2018 Apr 2.

School of Biotechnology and Biomolecular Sciences, University of New South Wales (UNSW) Sydney, Sydney, New South Wales, Australia.

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http://www.nature.com/articles/s41588-018-0085-0
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http://dx.doi.org/10.1038/s41588-018-0085-0DOI Listing
April 2018

Efficacy of Denosumab for Glucocorticoid-Induced Osteoporosis in an Adolescent Patient with Duchenne Muscular Dystrophy: A Case Report.

JBJS Case Connect 2018 Apr-Jun;8(2):e22

Departments of Orthopaedic Surgery (D.K., Y.N., T.S., and H.K.) and Medical Genetics (T.K.) and Third Department of Medicine (A.N.), Shinshu University School of Medicine, Matsumoto, Japan.

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http://dx.doi.org/10.2106/JBJS.CC.17.00190DOI Listing
April 2018

Pretreatment of daily teriparatide enhances the increase of bone mineral density in cortical bones by denosumab therapy.

Ther Clin Risk Manag 2018 3;14:637-642. Epub 2018 Apr 3.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

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http://dx.doi.org/10.2147/TCRM.S154686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892610PMC
April 2018

Comparison of the effects of denosumab with either active vitamin D or native vitamin D on bone mineral density and bone turnover markers in postmenopausal osteoporosis.

Mod Rheumatol 2018 Mar 11;28(2):376-379. Epub 2017 Apr 11.

a Department of Orthopaedic Surgery , Shinshu University School of Medicine , Matsumoto, Nagano , Japan.

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http://dx.doi.org/10.1080/14397595.2017.1308454DOI Listing
March 2018

A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression.

Blood Cells Mol Dis 2018 03 29;69:1-9. Epub 2017 Nov 29.

Department of Medicine, Section of Hematology-Oncology, Boston University School of Medicine, Boston, MA 02118, USA; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2017.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783741PMC
March 2018

Effects of denosumab on bone metabolism and bone mineral density with anti-TNF inhibitors, tocilizumab, or abatacept in osteoporosis with rheumatoid arthritis.

Ther Clin Risk Manag 2018 1;14:453-459. Epub 2018 Mar 1.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto.

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http://dx.doi.org/10.2147/TCRM.S156350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840187PMC
March 2018

Efficacy of Denosumab for Osteoporosis in Two Patients with Adult-Onset Still's Disease-Denosumab Efficacy in Osteoporotic Still's Disease Patients.

J Clin Med 2018 Mar 22;7(4). Epub 2018 Mar 22.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto 390-8621, Japan.

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http://dx.doi.org/10.3390/jcm7040063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920437PMC
March 2018

Novel method for evaluation of hindfoot alignment in weight-bearing position using laser beam.

J Phys Ther Sci 2018 Mar 2;30(3):474-478. Epub 2018 Mar 2.

Department of Human Intelligence Systems, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Japan.

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http://dx.doi.org/10.1589/jpts.30.474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857461PMC
March 2018

Clinical Implications of Hip Flexion in the Measurement of Spinal Bone Mineral Density.

J Clin Densitom 2016 Jul-Sep;19(3):270-6. Epub 2016 Jan 5.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

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http://dx.doi.org/10.1016/j.jocd.2015.11.002DOI Listing
February 2018

Hsp90 chaperones hemoglobin maturation in erythroid and nonerythroid cells.

Proc Natl Acad Sci U S A 2018 02 22;115(6):E1117-E1126. Epub 2018 Jan 22.

Department of Pathobiology, Lerner Research Institute, The Cleveland Clinic, Cleveland, OH 44195;

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http://dx.doi.org/10.1073/pnas.1717993115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819442PMC
February 2018

Vitamin D and Calcium Addition during Denosumab Therapy over a Period of Four Years Significantly Improves Lumbar Bone Mineral Density in Japanese Osteoporosis Patients.

Nutrients 2018 Feb 27;10(3). Epub 2018 Feb 27.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto 390-8621, Japan.

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http://dx.doi.org/10.3390/nu10030272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872690PMC
February 2018

Bony findings detected by MRI may reflect the pathophysiology of osteoarthritis with thumb carpometacarpal joint pain.

Int J Rheum Dis 2017 Dec 18;20(12):1950-1957. Epub 2015 Nov 18.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

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http://dx.doi.org/10.1111/1756-185X.12781DOI Listing
December 2017

Vitamin D and calcium are required at the time of denosumab administration during osteoporosis treatment.

Bone Res 2017 10;5:17021. Epub 2017 Oct 10.

Department of Orthopedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

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http://dx.doi.org/10.1038/boneres.2017.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634512PMC
October 2017

Denosumab significantly improves bone mineral density with or without bisphosphonate pre-treatment in osteoporosis with rheumatoid arthritis : Denosumab improves bone mineral density in osteoporosis with rheumatoid arthritis.

Arch Osteoporos 2017 Sep 21;12(1):80. Epub 2017 Sep 21.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto, 390-8621, Japan.

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http://dx.doi.org/10.1007/s11657-017-0371-yDOI Listing
September 2017

KLF1 drives the expression of fetal hemoglobin in British HPFH.

Blood 2017 08 28;130(6):803-807. Epub 2017 Jun 28.

School of Biotechnology and Biomolecular Sciences, University of New South Wales (UNSW Sydney), Sydney, NSW, Australia.

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http://dx.doi.org/10.1182/blood-2017-02-767400DOI Listing
August 2017

Changes of Bone-Related Minerals during Denosumab Administration in Post-Menopausal Osteoporotic Patients.

Nutrients 2017 Aug 13;9(8). Epub 2017 Aug 13.

Department of Orthopedic Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto 390-8621, Japan.

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http://dx.doi.org/10.3390/nu9080871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579664PMC
August 2017

FANTOM5 CAGE profiles of human and mouse samples.

Authors:
Shuhei Noguchi Takahiro Arakawa Shiro Fukuda Masaaki Furuno Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Kaoru Kaida Ai Kaiho Mutsumi Kanamori-Katayama Tsugumi Kawashima Miki Kojima Atsutaka Kubosaki Ri-Ichiroh Manabe Mitsuyoshi Murata Sayaka Nagao-Sato Kenichi Nakazato Noriko Ninomiya Hiromi Nishiyori-Sueki Shohei Noma Eri Saijyo Akiko Saka Mizuho Sakai Christophe Simon Naoko Suzuki Michihira Tagami Shoko Watanabe Shigehiro Yoshida Peter Arner Richard A Axton Magda Babina J Kenneth Baillie Timothy C Barnett Anthony G Beckhouse Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher Ailsa J Carlisle Hans C Clevers Carrie A Davis Michael Detmar Taeko Dohi Albert S B Edge Matthias Edinger Anna Ehrlund Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Mary C Farach-Carson Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley M Forrester Rie Fujita Jun-Ichi Furusawa Teunis B Geijtenbeek Thomas Gingeras Daniel Goldowitz Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Yuki Hasegawa Meenhard Herlyn Peter Heutink Kelly J Hitchens David A Hume Tomokatsu Ikawa Yuri Ishizu Chieko Kai Hiroshi Kawamoto Yuki I Kawamura Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura Sarah Klein S Peter Klinken Alan J Knox Soichi Kojima Haruhiko Koseki Shigeo Koyasu Weonju Lee Andreas Lennartsson Alan Mackay-Sim Niklas Mejhert Yosuke Mizuno Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Kelly J Morris Hozumi Motohashi Christine L Mummery Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Tadasuke Nozaki Soichi Ogishima Naganari Ohkura Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Swati Pradhan-Bhatt Xian-Yang Qin Michael Rehli Patrizia Rizzu Sugata Roy Antti Sajantila Shimon Sakaguchi Hiroki Sato Hironori Satoh Suzana Savvi Alka Saxena Christian Schmidl Claudio Schneider Gundula G Schulze-Tanzil Anita Schwegmann Guojun Sheng Jay W Shin Daisuke Sugiyama Takaaki Sugiyama Kim M Summers Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Andru Tomoiu Hiroo Toyoda Marc van de Wetering Linda M van den Berg Roberto Verardo Dipti Vijayan Christine A Wells Louise N Winteringham Ernst Wolvetang Yoko Yamaguchi Masayuki Yamamoto Chiyo Yanagi-Mizuochi Misako Yoneda Yohei Yonekura Peter G Zhang Silvia Zucchelli Imad Abugessaisa Erik Arner Jayson Harshbarger Atsushi Kondo Timo Lassmann Marina Lizio Serkan Sahin Thierry Sengstag Jessica Severin Hisashi Shimoji Masanori Suzuki Harukazu Suzuki Jun Kawai Naoto Kondo Masayoshi Itoh Carsten O Daub Takeya Kasukawa Hideya Kawaji Piero Carninci Alistair R R Forrest Yoshihide Hayashizaki

Sci Data 2017 08 29;4:170112. Epub 2017 Aug 29.

RIKEN Omics Science Center, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1038/sdata.2017.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574368PMC
August 2017

A specialized pathway for erythroid iron delivery through lysosomal trafficking of transferrin receptor 2.

Blood Adv 2017 Jun 27;1(15):1181-1194. Epub 2017 Jun 27.

Department of Pathology, University of Virginia School of Medicine, Charlottesville, VA.

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http://dx.doi.org/10.1182/bloodadvances.2016003772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728310PMC
June 2017

Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci.

Nat Genet 2017 Apr 20;49(4):625-634. Epub 2017 Feb 20.

Division of Hematology/Oncology, Boston Children's Hospital; Department of Pediatric Oncology, Dana-Farber Cancer Institute; Harvard Stem Cell Institute; and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374001PMC
April 2017

Vitamin D and Calcium Are Required during Denosumab Treatment in Osteoporosis with Rheumatoid Arthritis.

Nutrients 2017 Apr 26;9(5). Epub 2017 Apr 26.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto 390-8621, Japan.

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http://www.mdpi.com/2072-6643/9/5/428
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http://dx.doi.org/10.3390/nu9050428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452158PMC
April 2017

An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors.

Stem Cell Reports 2017 03 23;8(3):500-508. Epub 2017 Feb 23.

Laboratory of Stem Cell Therapy, Center for Experimental Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan; Project Division of Advanced Regenerative Medicine, The Institute of Medical Science, the University of Tokyo, Tokyo 108-8639, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355634PMC
March 2017

Painful locking of the wrist in a patient with pseudoachondroplasia confirmed by COMP mutation.

J Surg Case Rep 2017 Jan 2;2017(1). Epub 2017 Jan 2.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

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http://dx.doi.org/10.1093/jscr/rjw216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204134PMC
January 2017

Genome-wide analysis of canonical Wnt target gene regulation in Xenopus tropicalis challenges β-catenin paradigm.

Genesis 2017 01;55(1-2)

Institute of Medical Sciences, Foresterhill Health Campus, University of Aberdeen, Aberdeen, AB25 2ZD, United Kingdom.

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http://dx.doi.org/10.1002/dvg.22991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299483PMC
January 2017

Goniothalamin induces mitochondria-mediated apoptosis associated with endoplasmic reticulum stress-induced activation of JNK in HeLa cells.

Oncol Lett 2017 Jan 11;13(1):119-128. Epub 2016 Nov 11.

Department of Biochemistry, Faculty of Medicine, Srinkharinwirot University, Bangkok 10110, Thailand.

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http://dx.doi.org/10.3892/ol.2016.5381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245090PMC
January 2017

Monthly minodronate inhibits bone resorption to a greater extent than does monthly risedronate.

Osteoporos Sarcopenia 2016 Sep 3;2(3):170-174. Epub 2016 Aug 3.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Nagano, Japan.

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http://dx.doi.org/10.1016/j.afos.2016.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372746PMC
September 2016

Associations of self-reported height loss and kyphosis with vertebral fractures in Japanese women 60 years and older: a cross-sectional survey.

Sci Rep 2016 07 6;6:29199. Epub 2016 Jul 6.

Department of Oral and Maxillofacial Radiology, School of Dentistry, Matsumoto Dental University, 1170 Gobara Hirooka, Shiojiri 399-0781, Japan.

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http://dx.doi.org/10.1038/srep29199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933969PMC
July 2016

Tissue- and stage-specific Wnt target gene expression is controlled subsequent to β-catenin recruitment to cis-regulatory modules.

Development 2016 06 11;143(11):1914-25. Epub 2016 Apr 11.

Institute of Medical Sciences, Foresterhill Health Campus, University of Aberdeen, Aberdeen AB25 2ZD, UK

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http://dx.doi.org/10.1242/dev.131664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920159PMC
June 2016

Bisphosphonate Pre-Treatment Diminishes the Therapeutic Benefits of Teriparatide in Japanese Osteoporotic Patients.

Tohoku J Exp Med 2016 05;239(1):17-24

Center for Osteoporosis and Spinal Disorders, Kamimura Orthopaedic Clinic.

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http://dx.doi.org/10.1620/tjem.239.17DOI Listing
May 2016

Identification of a novel putative mitochondrial protein FAM210B associated with erythroid differentiation.

Int J Hematol 2016 Apr 11;103(4):387-95. Epub 2016 Mar 11.

Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai, 980-8575, Japan.

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http://dx.doi.org/10.1007/s12185-016-1968-4DOI Listing
April 2016

Risk factors of adjacent vertebral collapse after percutaneous vertebroplasty for osteoporotic vertebral fracture in postmenopausal women.

BMC Musculoskelet Disord 2016 Jan 12;17:12. Epub 2016 Jan 12.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto, 390-8621, Japan.

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http://dx.doi.org/10.1186/s12891-016-0887-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711009PMC
January 2016

Bone alterations are associated with ankle osteoarthritis joint pain.

Sci Rep 2016 Jan 18;6:18717. Epub 2016 Jan 18.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto 390-8621, Japan.

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http://dx.doi.org/10.1038/srep18717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726085PMC
January 2016

Goniothalamin enhances TRAIL-induced apoptosis in colorectal cancer cells through DR5 upregulation and cFLIP downregulation.

Int J Oncol 2015 Dec 13;47(6):2188-96. Epub 2015 Oct 13.

Department of Biochemistry, Faculty of Medicine, Srinkharinwirot University, Bangkok 10110, Thailand.

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http://dx.doi.org/10.3892/ijo.2015.3204DOI Listing
December 2015

Mapping Mammalian Cell-type-specific Transcriptional Regulatory Networks Using KD-CAGE and ChIP-seq Data in the TC-YIK Cell Line.

Front Genet 2015 18;6:331. Epub 2015 Nov 18.

RIKEN Center for Life Science Technologies Yokohama, Japan ; Division of Genomic Technologies, RIKEN Center for Life Science Technologies Yokohama, Japan ; QEII Medical Centre and Centre for Medical Research, Harry Perkins Institute of Medical Research, The University of Western Australia Nedlands, WA, Australia.

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http://dx.doi.org/10.3389/fgene.2015.00331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650373PMC
December 2015

Eldecalcitol, in Combination with Bisphosphonate, Is Effective for Treatment of Japanese Osteoporotic Patients.

Tohoku J Exp Med 2015 12;237(4):339-43

Department of Orthopedic Surgery, Shinshu University School of Medicine.

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http://dx.doi.org/10.1620/tjem.237.339DOI Listing
December 2015