Yuk Ming Lo

Yuk Ming Dennis Lo

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Yuk Ming Lo

Yuk Ming Dennis Lo

Publications by authors named "Yuk Ming Dennis Lo"

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1PubMed Central Citations

Plasma Epstein-Barr virus DNA as an archetypal circulating tumour DNA marker.

J Pathol 2019 Apr 25;247(5):641-649. Epub 2019 Feb 25.

Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR.

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http://dx.doi.org/10.1002/path.5249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594142PMC
April 2019

Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamics.

Proc Natl Acad Sci U S A 2017 09 22;114(37):E7786-E7795. Epub 2017 Aug 22.

Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China;

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http://dx.doi.org/10.1073/pnas.1710470114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604038PMC
September 2017

Gestational Age Assessment by Methylation and Size Profiling of Maternal Plasma DNA: A Feasibility Study.

Clin Chem 2017 02 15;63(2):606-608. Epub 2016 Dec 15.

Li Ka Shing Institute of Health Sciences The Chinese University of Hong Kong Shatin, New Territories, Hong Kong SAR, China

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http://dx.doi.org/10.1373/clinchem.2016.265702DOI Listing
February 2017

Cell-free DNA in maternal plasma and serum: A comparison of quantity, quality and tissue origin using genomic and epigenomic approaches.

Clin Biochem 2016 Dec 9;49(18):1379-1386. Epub 2016 Sep 9.

Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2016.09.009DOI Listing
December 2016

Second generation noninvasive fetal genome analysis reveals de novo mutations, single-base parental inheritance, and preferred DNA ends.

Proc Natl Acad Sci U S A 2016 12 31;113(50):E8159-E8168. Epub 2016 Oct 31.

Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong;

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http://dx.doi.org/10.1073/pnas.1615800113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167168PMC
December 2016

Tracing the tissue of origin of plasma DNA-feasibility and implications.

Ann N Y Acad Sci 2016 07 15;1376(1):14-7. Epub 2016 Aug 15.

Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.

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http://dx.doi.org/10.1111/nyas.13163DOI Listing
July 2016

FetalQuant: accurate quantification of fetal DNA fraction by shallow-depth sequencing of maternal plasma DNA.

NPJ Genom Med 2016 11;1:16013. Epub 2016 May 11.

Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1038/npjgenmed.2016.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685300PMC
May 2016

Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments.

Proc Natl Acad Sci U S A 2015 Oct 21;112(40):E5503-12. Epub 2015 Sep 21.

Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China; State Key Laboratory in Oncology in South China, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China;

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http://dx.doi.org/10.1073/pnas.1508736112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603482PMC
October 2015

Maternal plasma fetal DNA fractions in pregnancies with low and high risks for fetal chromosomal aneuploidies.

PLoS One 2014 28;9(2):e88484. Epub 2014 Feb 28.

Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China ; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088484PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938419PMC
November 2014

Noninvasive prenatal molecular karyotyping from maternal plasma.

PLoS One 2013 17;8(4):e60968. Epub 2013 Apr 17.

Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060968PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629174PMC
November 2013

The potential clinical utility of serial plasma albumin mRNA monitoring for the post-liver transplantation management.

Clin Biochem 2013 Oct 30;46(15):1313-9. Epub 2013 Apr 30.

Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China.

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http://dx.doi.org/10.1016/j.clinbiochem.2013.04.022DOI Listing
October 2013

Genomic analysis of fetal nucleic acids in maternal blood.

Annu Rev Genomics Hum Genet 2012 29;13:285-306. Epub 2012 May 29.

Li Ka Shing Institute of Health Sciences and Department of Chemical Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.

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http://dx.doi.org/10.1146/annurev-genom-090711-163806DOI Listing
January 2013

Clinical applications of maternal plasma fetal DNA analysis: translating the fruits of 15 years of research.

Clin Chem Lab Med 2013 Jan;51(1):197-204

Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, P.R. China.

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http://dx.doi.org/10.1515/cclm-2012-0601DOI Listing
January 2013

Recent advances in the analysis of fetal nucleic acids in maternal plasma.

Curr Opin Hematol 2012 Nov;19(6):462-8

Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, Hong Kong, China.

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http://dx.doi.org/10.1097/MOH.0b013e328358e17aDOI Listing
November 2012

FetalQuant: deducing fractional fetal DNA concentration from massively parallel sequencing of DNA in maternal plasma.

Bioinformatics 2012 Nov 8;28(22):2883-90. Epub 2012 Sep 8.

Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.

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http://dx.doi.org/10.1093/bioinformatics/bts549DOI Listing
November 2012

Fetal nucleic acids in maternal blood: the promises.

Clin Chem Lab Med 2012 Jun;50(6):995-8

Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR , PR China.

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https://www.degruyter.com/view/j/cclm.2012.50.issue-6/cclm.2
Publisher Site
http://dx.doi.org/10.1515/CCLM.2011.765DOI Listing
June 2012

Non-invasive prenatal diagnosis by massively parallel sequencing of maternal plasma DNA.

Open Biol 2012 Jun;2(6):120086

Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, People's Republic of China.

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http://dx.doi.org/10.1098/rsob.120086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390796PMC
June 2012

Noninvasive fetal trisomy 21 detection using chromosome-selective sequencing: a variation of the molecular counting theme.

Expert Rev Mol Diagn 2012 May;12(4):329-31

Li Ka Shing Institute of Health Sciences & Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.

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http://dx.doi.org/10.1586/erm.12.24DOI Listing
May 2012

Host-response biomarkers for diagnosis of late-onset septicemia and necrotizing enterocolitis in preterm infants.

J Clin Invest 2010 Aug 1;120(8):2989-3000. Epub 2010 Jul 1.

Department of Pediatrics, Prince of Wales Hospital, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1172/JCI40196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912182PMC
August 2010

Elevated gene expression of Th1/Th2 associated transcription factors is correlated with disease activity in patients with systemic lupus erythematosus.

J Rheumatol 2007 Jan 15;34(1):89-96. Epub 2006 Nov 15.

Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.

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January 2007

Plasma epigenetic markers for cancer detection and prenatal diagnosis.

Front Biosci 2006 Sep 1;11:2647-56. Epub 2006 Sep 1.

Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, China.

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September 2006

MALDI-TOF mass spectrometry for quantitative, specific, and sensitive analysis of DNA and RNA.

Ann N Y Acad Sci 2006 Sep;1075:282-7

Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China.

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http://dx.doi.org/10.1196/annals.1368.038DOI Listing
September 2006

Circulating DNA analysis: protocols and clinical applications using TaqMan assays.

Methods Mol Med 2004 ;97:217-36

Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, New Territories, Hong Kong.

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http://dx.doi.org/10.1385/1-59259-760-2:217DOI Listing
May 2004