Publications by authors named "Yujin Hoshida"

98Publications

Clinical and Molecular Prediction of Hepatocellular Carcinoma Risk.

J Clin Med 2020 Nov 26;9(12). Epub 2020 Nov 26.

Liver Tumor Translational Research Program, Simmons Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.

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http://dx.doi.org/10.3390/jcm9123843DOI Listing
November 2020

Risk Factors, Pathogenesis, and Strategies for Hepatocellular Carcinoma Prevention: Emphasis on Secondary Prevention and Its Translational Challenges.

J Clin Med 2020 Nov 25;9(12). Epub 2020 Nov 25.

Division of Surgical Oncology, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.3390/jcm9123817DOI Listing
November 2020

Viral Exposure Signature Associated with Liver Cancer Risk.

Trends Mol Med 2020 08 10;26(8):711-713. Epub 2020 Jul 10.

Liver Tumor Translational Research Program, Simmons Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2020.06.008DOI Listing
August 2020

Thrombocytosis is associated with worse survival in patients with hepatocellular carcinoma.

Liver Int 2020 Oct 28;40(10):2522-2534. Epub 2020 Jun 28.

Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.1111/liv.14560DOI Listing
October 2020

Brazilian cohort and genes encoding for drug-metabolizing enzymes and drug transporters.

Pharmacogenomics 2020 06 3;21(9):575-586. Epub 2020 Jun 3.

Division of Clinical Gastroenterology & Hepatology, Department of Gastroenterology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, 05403-000, Brazil.

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http://dx.doi.org/10.2217/pgs-2020-0013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362932PMC
June 2020

Omics-derived hepatocellular carcinoma risk biomarkers for precision care of chronic liver diseases.

Hepatol Res 2020 Jul 15;50(7):817-830. Epub 2020 May 15.

Liver Tumor Translational Research Program, Simmons Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1111/hepr.13506DOI Listing
July 2020

Epigallocatechin Gallate Induces Hepatic Stellate Cell Senescence and Attenuates Development of Hepatocellular Carcinoma.

Cancer Prev Res (Phila) 2020 06 6;13(6):497-508. Epub 2020 Apr 6.

Division of Surgical Oncology, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1940-6207.CAPR-19-0383DOI Listing
June 2020

MRI radiomics features predict immuno-oncological characteristics of hepatocellular carcinoma.

Eur Radiol 2020 Jul 21;30(7):3759-3769. Epub 2020 Feb 21.

Biomedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.

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http://dx.doi.org/10.1007/s00330-020-06675-2DOI Listing
July 2020

Restricted immunological and cellular pathways are shared by murine models of chronic alcohol consumption.

Sci Rep 2020 02 12;10(1):2451. Epub 2020 Feb 12.

Division of Digestive Diseases and Nutrition, Section of Hepatology, Rush University, Chicago, IL, USA.

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http://dx.doi.org/10.1038/s41598-020-59188-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016184PMC
February 2020

Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury.

Gastroenterology 2020 05 20;158(6):1698-1712.e14. Epub 2020 Jan 20.

Children's Research Institute, Departments of Pediatrics and Internal Medicine, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2020.01.026DOI Listing
May 2020

Shared and Tissue-Specific Expression Signatures between Bone Marrow from Primary Myelofibrosis and Essential Thrombocythemia.

Exp Hematol 2019 11 1;79:16-25.e3. Epub 2019 Nov 1.

Division of Hematology and Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Biomedical and Neuromotorial Sciences, Alma Mater University, Bologna, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2019.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910948PMC
November 2019

MPIC: Molecular Prognostic Indicators in Cirrhosis Database for Clinical Context-Specific Prognostic Biomarker Validation.

Front Genet 2019 18;10:830. Epub 2019 Sep 18.

Liver Tumor Translational Research Program, Simmons Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States.

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http://dx.doi.org/10.3389/fgene.2019.00830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759478PMC
September 2019

Gene signature-MELD score and alcohol relapse determine long-term prognosis of patients with severe alcoholic hepatitis.

Liver Int 2020 03 15;40(3):565-570. Epub 2019 Oct 15.

Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1111/liv.14265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056530PMC
March 2020

Use of big data in drug development for precision medicine: an update.

Expert Rev Precis Med Drug Dev 2019 20;4(3):189-200. Epub 2019 May 20.

Liver Tumor Translational Research Program, Simmons Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1080/23808993.2019.1617632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613936PMC
May 2019

Dose and Duration of Aspirin Use to Reduce Incident Hepatocellular Carcinoma.

Hepatology 2019 12 7;70(6):2216-2217. Epub 2019 Aug 7.

Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.

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http://dx.doi.org/10.1002/hep.30813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885093PMC
December 2019

Addressing the Challenges of Hepatitis C Cure and Persistent Risk of Hepatocellular Carcinoma.

Viruses 2019 05 15;11(5). Epub 2019 May 15.

Liver Tumor Translational Research Program, Harold C. Simmons Comprehensive Cancer Center, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.3390/v11050441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563310PMC
May 2019

Hepatocellular Carcinoma Risk Stratification by Genetic Profiling in Patients with Cirrhosis.

Semin Liver Dis 2019 May 25;39(2):153-162. Epub 2019 Mar 25.

Liver Tumor Translational Research Program, Simmons Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1681031
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http://dx.doi.org/10.1055/s-0039-1681031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641542PMC
May 2019

Aspirin: Does it Have a Role for Chemoprevention of Hepatocellular Carcinoma?

Gastroenterology 2019 04 5;156(5):1530-1531. Epub 2019 Mar 5.

Division of Digestive and Liver Diseases, UT Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1053/j.gastro.2019.03.006DOI Listing
April 2019

HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response.

Gastroenterology 2019 06 2;156(8):2313-2329.e7. Epub 2019 Mar 2.

INSERM U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg, France; Université de Strasbourg, Strasbourg, France; Institut Hospitalo-Universitaire, Pôle Hépato-digestif, Nouvel Hôpital Civil, Strasbourg, France; Institut Universitaire de France (IUF), Paris, France. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.02.038DOI Listing
June 2019

Pioglitazone Reduces Hepatocellular Carcinoma Development in Two Rodent Models of Cirrhosis.

J Gastrointest Surg 2019 01 26;23(1):101-111. Epub 2018 Oct 26.

Division of Surgical Oncology, Massachusetts General Hospital Cancer Center and Harvard Medical School, 55 Fruit Street, WRN 401, Boston, MA, 02114, USA.

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http://link.springer.com/10.1007/s11605-018-4004-6
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http://dx.doi.org/10.1007/s11605-018-4004-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328630PMC
January 2019

Molecular heterogeneity in hepatocellular carcinoma.

Hepat Oncol 2018 Jan 11;5(1):HEP10. Epub 2018 Sep 11.

Liver Tumor Translational Research Program, Harold C. Simmons Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.2217/hep-2018-0005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168045PMC
January 2018

Generic chemoprevention of hepatocellular carcinoma.

Ann N Y Acad Sci 2019 03 17;1440(1):23-35. Epub 2018 Sep 17.

Liver Tumor Translational Research Program, Simmons Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1111/nyas.13971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420365PMC
March 2019

Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import.

Cell 2018 08 9;174(5):1200-1215.e20. Epub 2018 Aug 9.

Cancer Biology Department, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA; Medical Oncology Department, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA; Pathology Department, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150493PMC
August 2018

GIGSEA: genotype imputed gene set enrichment analysis using GWAS summary level data.

Bioinformatics 2019 01;35(1):160-163

Department of Genetics and Genomic Sciences and Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1093/bioinformatics/bty529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298047PMC
January 2019

A simple diet- and chemical-induced murine NASH model with rapid progression of steatohepatitis, fibrosis and liver cancer.

J Hepatol 2018 08 21;69(2):385-395. Epub 2018 Mar 21.

Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054570PMC
August 2018

In vitro modeling of hepatocellular carcinoma molecular subtypes for anti-cancer drug assessment.

Exp Mol Med 2018 01 5;50(1):e419. Epub 2018 Jan 5.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1038/emm.2017.164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992986PMC
January 2018

Cell type-specific pharmacological kinase inhibition for cancer chemoprevention.

Nanomedicine 2018 02 20;14(2):317-325. Epub 2017 Nov 20.

Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2017.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844817PMC
February 2018

Integrin alpha 11 in the regulation of the myofibroblast phenotype: implications for fibrotic diseases.

Exp Mol Med 2017 11 17;49(11):e396. Epub 2017 Nov 17.

Targeted Therapeutics, Department of Biomaterials Science and Technology, MIRA Institute for Biomedical Technology and Technical Medicine, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.

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http://dx.doi.org/10.1038/emm.2017.213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704196PMC
November 2017

Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine.

J Hepatol 2018 03 6;68(3):526-549. Epub 2017 Oct 6.

Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818315PMC
March 2018

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling.

Development 2017 08 11;144(16):2925-2939. Epub 2017 Jul 11.

Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, Box 1020, New York, NY 10029, USA

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http://dx.doi.org/10.1242/dev.147629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592811PMC
August 2017

Cost-Effectiveness of Risk Score-Stratified Hepatocellular Carcinoma Screening in Patients with Cirrhosis.

Clin Transl Gastroenterol 2017 Jun 22;8(6):e101. Epub 2017 Jun 22.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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http://dx.doi.org/10.1038/ctg.2017.26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518949PMC
June 2017

Patient-derived Interstitial Fluids and Predisposition to Aggressive Sporadic Breast Cancer through Collagen Remodeling and Inactivation of p53.

Clin Cancer Res 2017 Sep 19;23(18):5446-5459. Epub 2017 Jun 19.

Tisch Cancer Institute, Division of Hematology and Medical Oncology of the Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-0342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600839PMC
September 2017

The autotaxin-lysophosphatidic acid pathway emerges as a therapeutic target to prevent liver cancer.

Mol Cell Oncol 2017 31;4(3):e1311827. Epub 2017 Mar 31.

Division of Surgical Oncology, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1080/23723556.2017.1311827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462520PMC
March 2017

Hepatic stellate cells as key target in liver fibrosis.

Adv Drug Deliv Rev 2017 11 12;121:27-42. Epub 2017 May 12.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Division of Liver Diseases, Department of Medicine, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2017.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682243PMC
November 2017

Persisting risk of hepatocellular carcinoma after hepatitis C virus cure monitored by a liver transcriptome signature.

Hepatology 2017 10 26;66(4):1344-1346. Epub 2017 Aug 26.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1002/hep.29203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605396PMC
October 2017

Tailored algorithms for hepatocellular carcinoma surveillance: Is one-size-fits-all strategy outdated?

Curr Hepatol Rep 2017 Mar 1;16(1):64-71. Epub 2017 Feb 1.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, USA.

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http://dx.doi.org/10.1007/s11901-017-0336-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358664PMC
March 2017

Hepatitis C-related hepatocellular carcinoma in the era of new generation antivirals.

BMC Med 2017 03 14;15(1):52. Epub 2017 Mar 14.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, 1470 Madison Ave, Box 1123, New York, NY, 10029, USA.

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http://dx.doi.org/10.1186/s12916-017-0815-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348895PMC
March 2017

Transcriptome-based repurposing of apigenin as a potential anti-fibrotic agent targeting hepatic stellate cells.

Sci Rep 2017 03 3;7:42563. Epub 2017 Mar 3.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, USA.

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http://dx.doi.org/10.1038/srep42563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335661PMC
March 2017

The XBP1 Arm of the Unfolded Protein Response Induces Fibrogenic Activity in Hepatic Stellate Cells Through Autophagy.

Sci Rep 2016 12 20;6:39342. Epub 2016 Dec 20.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, US.

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http://dx.doi.org/10.1038/srep39342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172197PMC
December 2016

The role of GATA2 in lethal prostate cancer aggressiveness.

Nat Rev Urol 2017 Jan 22;14(1):38-48. Epub 2016 Nov 22.

Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

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http://dx.doi.org/10.1038/nrurol.2016.225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489122PMC
January 2017

Tratamiento personalizado del carcinoma hepatocelular basado en información molecular: perspectivas futuras.

Clin Liver Dis (Hoboken) 2016 Nov 10;8(Suppl 1):S43-S48. Epub 2016 Nov 10.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute Icahn School of Medicine at Mount Sinai New York NY, EE. UU.

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http://dx.doi.org/10.1002/cld.601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490229PMC
November 2016

Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes.

Cell Rep 2016 10;17(5):1357-1368

INSERM, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, 67000 Strasbourg, France; Université de Strasbourg, 67000 Strasbourg, France; Institut Hospitalo-universitaire, Pôle Hépato-digestif, Nouvel Hôpital Civil, 67000 Strasbourg, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.09.084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098118PMC
October 2016

Using Big Data to Discover Diagnostics and Therapeutics for Gastrointestinal and Liver Diseases.

Gastroenterology 2017 01 20;152(1):53-67.e3. Epub 2016 Oct 20.

Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1053/j.gastro.2016.09.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193106PMC
January 2017

Chronic hepatitis C virus infection and pathogenesis of hepatocellular carcinoma.

Curr Opin Virol 2016 10 11;20:99-105. Epub 2016 Oct 11.

Inserm, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg, France; Université de Strasbourg, Strasbourg, France. Electronic address:

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http://dx.doi.org/10.1016/j.coviro.2016.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120759PMC
October 2016

Use of big data in drug development for precision medicine.

Expert Rev Precis Med Drug Dev 2016;1(3):245-253. Epub 2016 Apr 28.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA.

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http://dx.doi.org/10.1080/23808993.2016.1174062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943760PMC
April 2016

Comparative Epigenomic Profiling of the DNA Methylome in Mouse and Zebrafish Uncovers High Interspecies Divergence.

Front Genet 2016 17;7:110. Epub 2016 Jun 17.

Department of Medicine/Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New YorkNY, USA; Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New YorkNY, USA; Liver Cancer Program/Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New YorkNY, USA; Program in Biology, New York University Abu DhabiAbu Dhabi, UAE.

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http://dx.doi.org/10.3389/fgene.2016.00110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911366PMC
July 2016

Is Hepatocellular Cancer the Same Disease in Alcoholic and Nonalcoholic Fatty Liver Diseases?

Gastroenterology 2016 06 16;150(8):1710-7. Epub 2016 Jan 16.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120760PMC
June 2016

Tumour initiating cells and IGF/FGF signalling contribute to sorafenib resistance in hepatocellular carcinoma.

Gut 2017 03 11;66(3):530-540. Epub 2015 Dec 11.

Liver Cancer Translational Research Laboratory, Barcelona Clinic Liver Cancer (BCLC) Group, Liver Unit and Pathology Department, IDIBAPS, Hospital Clínic, CIBERehd, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1136/gutjnl-2015-309501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600200PMC
March 2017

Molecular classification of hepatocellular carcinoma: potential therapeutic implications.

Hepat Oncol 2015;2(4):371-379

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 1470 Madison Ave, PO Box 1123, New York, NY 10029, USA.

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http://dx.doi.org/10.2217/hep.15.26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662420PMC
January 2015

Molecular subclasses of hepatocellular carcinoma predict sensitivity to fibroblast growth factor receptor inhibition.

Int J Cancer 2016 Mar 9;138(6):1494-505. Epub 2015 Nov 9.

Division of Surgical Oncology, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA.

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http://doi.wiley.com/10.1002/ijc.29893
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http://dx.doi.org/10.1002/ijc.29893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297453PMC
March 2016

Molecular prognostic prediction in liver cirrhosis.

World J Gastroenterol 2015 Sep;21(36):10262-73

Nicolas Goossens, Shigeki Nakagawa, Yujin Hoshida, Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.

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http://dx.doi.org/10.3748/wjg.v21.i36.10262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579874PMC
September 2015

Induction and contribution of beta platelet-derived growth factor signalling by hepatic stellate cells to liver regeneration after partial hepatectomy in mice.

Liver Int 2016 06 21;36(6):874-82. Epub 2015 Sep 21.

Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1111/liv.12933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749477PMC
June 2016

Origin and interpretation of cancer transcriptome profiling: the essential role of the stroma in determining prognosis and drug resistance.

EMBO Mol Med 2015 Nov;7(11):1385-7

Division of Hematology and Oncology, Department of Medicine, Department of Otolaryngology, Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.15252/emmm.201505284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644372PMC
November 2015

Progenitor cell markers predict outcome of patients with hepatocellular carcinoma beyond Milan criteria undergoing liver transplantation.

J Hepatol 2015 Dec 26;63(6):1368-77. Epub 2015 Jul 26.

Mount Sinai Liver Cancer Program (Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Department of Pathology, Recanati Miller Transplantation Institute, Department of Surgical Oncology), Icahn School of Medicine at Mount Sinai, New York, USA; Liver Cancer Translational Research Laboratory, Barcelona - Clínic Liver Cancer Group (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Liver Unit, Hospital Clínic, Universitat de Barcelona, Catalonia, Spain; Institució Catalana de Recerca i Estudis Avançats, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2015.07.025DOI Listing
December 2015

Cancer biomarker discovery and validation.

Transl Cancer Res 2015 Jun;4(3):256-269

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA.

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http://dx.doi.org/10.3978/j.issn.2218-676X.2015.06.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511498PMC
June 2015

Personalized management of hepatocellular carcinoma based on molecular information: future prospects.

Clin Liver Dis (Hoboken) 2015 Jun;5(6):132-135

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA.

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http://dx.doi.org/10.1002/cld.483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512174PMC
June 2015

Hepatitis C virus-induced hepatocellular carcinoma.

Clin Mol Hepatol 2015 Jun 26;21(2):105-14. Epub 2015 Jun 26.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA.

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http://e-cmh.org/journal/view.php?doi=10.3350/cmh.2015.21.2.
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http://dx.doi.org/10.3350/cmh.2015.21.2.105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493352PMC
June 2015

Clinicopathological indices to predict hepatocellular carcinoma molecular classification.

Liver Int 2016 Jan 29;36(1):108-18. Epub 2015 Jun 29.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1111/liv.12889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674393PMC
January 2016

A hepatic stellate cell gene expression signature associated with outcomes in hepatitis C cirrhosis and hepatocellular carcinoma after curative resection.

Gut 2016 10 4;65(10):1754-64. Epub 2015 Jun 4.

Department of Medicine, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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http://dx.doi.org/10.1136/gutjnl-2015-309655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848165PMC
October 2016

Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype.

Neuro Oncol 2015 Nov 29;17(11):1486-96. Epub 2015 Mar 29.

Department of Cancer Biology, Dana-Farber Cancer Institute, and Harvard Medical School, Boston, Massachusetts (G.B., P.B., B.R.P., S.E.S., B.T., R.F.-L., C.S., R.S., R.B.); Broad Institute, Cambridge, Massachusetts (G.B., P.B., B.R.P., S.E.S., B.T., R.F.-L., T.G., R.B.); Pediatric Neuro-Oncology Program, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Dana-Farber Cancer Institute and Boston Children's Hospital, and Harvard Medical School, Boston, Massachusetts (P.B., L.C.G., M.W.K.); Liver Cancer Program, Tisch Cancer Institute, Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York (Y.H.); Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts (S.R., S.S., P.Y.W., A.H.L., K.L.L., J.A.C.); Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts (S.R., L.R., B.R., C.L.M., K.L.L.); Department of Neurosurgery, Acibadem University Medical Center, Istanbul, Turkey (M.O.); Department of Pathology, Acibadem University Medical Center, Istanbul, Turkey (A.S.); Department of Neurosurgery, Boston Children's Hospital, Boston, Massachusetts (L.C.G.); Departement de Cancerologie de l'enfant et de l'adolescent, Gustave Roussy and Unité Mixte de Recherche 8203 du Centre National de la Recherche Scientifique, Université Paris-Sud, Villejuif, France (J.G.); Department of Pathology, Boston Children's Hospital, Boston, Massachusetts (K.L.L.).

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http://dx.doi.org/10.1093/neuonc/nov045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648300PMC
November 2015

YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression.

Cell Rep 2015 Mar 12;10(10):1692-1707. Epub 2015 Mar 12.

Cancer Center, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA; Center for Regenerative Medicine, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA; Department of Medicine, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565791PMC
March 2015

β-PDGF receptor expressed by hepatic stellate cells regulates fibrosis in murine liver injury, but not carcinogenesis.

J Hepatol 2015 Jul 9;63(1):141-7. Epub 2015 Feb 9.

Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2015.01.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475471PMC
July 2015

DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma.

Hepatology 2015 Jun 18;61(6):1945-56. Epub 2015 Mar 18.

Liver Cancer Research Program, Division of Liver Diseases, Tisch Cancer Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1002/hep.27732DOI Listing
June 2015