Yujiang Geno Shi

Yujiang Geno Shi

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Yujiang Geno Shi

Yujiang Geno Shi

Publications by authors named "Yujiang Geno Shi"

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Kdm1a promotes SCLC progression by transcriptionally silencing the tumor suppressor Rest.

Biochem Biophys Res Commun 2019 Jul 27;515(1):214-221. Epub 2019 May 27.

Division of Endocrinology, Brigham and Women Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.05.118DOI Listing
July 2019

Publisher Correction: N-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation.

Nat Chem Biol 2019 05;15(5):549

Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1038/s41589-019-0233-6DOI Listing
May 2019

TET2 stabilization by 14-3-3 binding to the phosphorylated Serine 99 is deregulated by mutations in cancer.

Cell Res 2019 Mar 3;29(3):248-250. Epub 2019 Jan 3.

Laboratory of Epigenetics, Liver Cancer Institute, Zhongshan Hospital, and Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China.

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http://www.nature.com/articles/s41422-018-0132-5
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http://dx.doi.org/10.1038/s41422-018-0132-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460428PMC
March 2019

NMethyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation.

Nat Chem Biol 2019 01 10;15(1):88-94. Epub 2018 Dec 10.

Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1038/s41589-018-0184-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463480PMC
January 2019

ERα is a negative regulator of PD-L1 gene transcription in breast cancer.

Biochem Biophys Res Commun 2018 10 18;505(1):157-161. Epub 2018 Sep 18.

Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China; Department of Cellular and Genetic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.09.005DOI Listing
October 2018

Zc3h13 Regulates Nuclear RNA mA Methylation and Mouse Embryonic Stem Cell Self-Renewal.

Mol Cell 2018 03;69(6):1028-1038.e6

Institute of Clinical Science, Zhongshan Hospital, and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P.R. China; Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China; Key Laboratory of Epigenetics, Department of Cellular and Genetic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China; The Fifth People's Hospital of Shanghai, Fudan University, Shanghai 200240, China. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858226PMC
March 2018

A primary role of TET proteins in establishment and maintenance of De Novo bivalency at CpG islands.

Nucleic Acids Res 2016 Oct 10;44(18):8682-8692. Epub 2016 Jun 10.

Laboratory of Epigenetics, Institutes of Biomedical Sciences, Shanghai Medical College of Fudan University, Shanghai 200032, China Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA

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http://dx.doi.org/10.1093/nar/gkw529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062965PMC
October 2016

Nono, a Bivalent Domain Factor, Regulates Erk Signaling and Mouse Embryonic Stem Cell Pluripotency.

Cell Rep 2016 10;17(4):997-1007

Key Laboratory of Birth Defects, Children's Hospital and Key Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai 201102, China; Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Cellular and Genetic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China; Newborn Medicine Division, Boston Children's Hospital, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086807PMC
http://dx.doi.org/10.1016/j.celrep.2016.09.078DOI Listing
October 2016

Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex.

Cell 2016 Apr;165(2):331-42

Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, and Key Laboratory of Epigenetics, Department of Cellular and Genetic Medicine, School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China; Key Laboratory of Birth Defect, Children's Hospital of Fudan University, Shanghai 201102, China; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Shanghai Cancer Center, Fudan University, Shanghai 200032, China. Electronic address:

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http://www.cell.com/cell/pdf/S0092-8674(16)30214-8.pdf
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http://www.cell.com/cms/attachment/2052648744/2059866671/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S009286741630214
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http://dx.doi.org/10.1016/j.cell.2016.02.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826479PMC
April 2016

BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing.

Mol Cell 2014 Oct 25;56(2):298-310. Epub 2014 Sep 25.

Epigenetics Laboratory, Institutes of Biomedical Sciences and School of Basic Medicine, Shanghai Medical College of Fudan University, Shanghai 200032, China; Division of Newborn Medicine and Program in Epigenetics, Department of Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.08.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363072PMC
October 2014

Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming.

Cell Stem Cell 2014 Apr 13;14(4):512-22. Epub 2014 Feb 13.

Shanghai Key Laboratory of Molecular Andrology, The State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909140000
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http://dx.doi.org/10.1016/j.stem.2014.01.001DOI Listing
April 2014

Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation.

Cell 2013 Dec 5;155(7):1545-55. Epub 2013 Dec 5.

Fudan University Shanghai Cancer Center, Department of Oncology and Institute of Biomedical Sciences, Shanghai Medical College of Fudan University, Shanghai 200032, China; State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200433, China. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2013.11.020DOI Listing
December 2013

The discovery of histone demethylases.

Cold Spring Harb Perspect Biol 2013 Sep 1;5(9). Epub 2013 Sep 1.

Harvard Medical School, and Endocrinology Division, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1101/cshperspect.a017947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753710PMC
September 2013

Genome-wide comparison of DNA hydroxymethylation in mouse embryonic stem cells and neural progenitor cells by a new comparative hMeDIP-seq method.

Nucleic Acids Res 2013 Apr 13;41(7):e84. Epub 2013 Feb 13.

Laboratory of Epigenetics, Institutes of Biomedical Sciences, Shanghai Medical College of Fudan University, Shanghai 200032, China.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkt091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627583PMC
April 2013

DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.

Mol Cell Biol 2013 Mar 7;33(6):1139-48. Epub 2013 Jan 7.

Laboratory of Epigenetics, Institute of Biomedical Sciences, and Department of Biochemistry, Fudan University Medical School, Shanghai, China.

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http://dx.doi.org/10.1128/MCB.01191-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592027PMC
March 2013

LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation.

Mol Cell 2013 Feb 20;49(3):558-70. Epub 2012 Dec 20.

Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine and Department of Biological Chemistry & Molecular Pharmacology, Brigham and Women's Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.molcel.2012.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625064PMC
February 2013

Tet family proteins and 5-hydroxymethylcytosine in development and disease.

Development 2012 Jun;139(11):1895-902

Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, PR China.

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http://dx.doi.org/10.1242/dev.070771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347683PMC
June 2012

M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability.

Proc Natl Acad Sci U S A 2012 Mar 12;109(13):4828-33. Epub 2012 Mar 12.

Laboratory of Epigenetics, Institute of Biomedical Sciences, and Department of Biochemistry, Fudan University Medical School, 138 Yixue Yuan Road, Shanghai 200032, China.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1116349109
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http://dx.doi.org/10.1073/pnas.1116349109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323953PMC
March 2012

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes.

Nature 2011 Sep 4;477(7366):606-10. Epub 2011 Sep 4.

Group of DNA Metabolism, The State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

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http://dx.doi.org/10.1038/nature10443DOI Listing
September 2011

Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation.

Mol Cell 2010 Jul;39(2):222-33

Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.molcel.2010.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518444PMC
July 2010