Yueh-Chiang Hu

Yueh-Chiang Hu

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Yueh-Chiang Hu

Yueh-Chiang Hu

Publications by authors named "Yueh-Chiang Hu"

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Knockout of latrophilin-3 in Sprague-Dawley rats causes hyperactivity, hyper-reactivity, under-response to amphetamine, and disrupted dopamine markers.

Neurobiol Dis 2019 Oct 6;130:104494. Epub 2019 Jun 6.

Department of Pediatrics, University of Cincinnati College of Medicine, Division of Neurology, Cincinnati Children's Hospital Medical Center, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.104494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689430PMC
October 2019

The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension.

Nat Commun 2019 Sep 12;10(1):4143. Epub 2019 Sep 12.

Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.

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http://dx.doi.org/10.1038/s41467-019-12226-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742632PMC
September 2019

Generation of CRISPR-Edited Rodents Using a Piezo-Driven Zygote Injection Technique.

Methods Mol Biol 2019 ;1874:169-178

Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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http://link.springer.com/10.1007/978-1-4939-8831-0_9
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http://dx.doi.org/10.1007/978-1-4939-8831-0_9DOI Listing
June 2019

Anthropoid primate-specific retroviral element THE1B controls expression of CRH in placenta and alters gestation length.

PLoS Biol 2018 09 19;16(9):e2006337. Epub 2018 Sep 19.

Division of Human Genetics, Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.2006337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166974PMC
September 2018

A Transgenic Core Facility's Experience in Genome Editing Revolution.

Adv Exp Med Biol 2017 ;1016:75-90

Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC7007, Cincinnati, OH, 45229, USA.

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http://dx.doi.org/10.1007/978-3-319-63904-8_4DOI Listing
April 2018

lncRNA Functional Networks in Oligodendrocytes Reveal Stage-Specific Myelination Control by an lncOL1/Suz12 Complex in the CNS.

Neuron 2017 Jan 29;93(2):362-378. Epub 2016 Dec 29.

Divisions of Experimental Hematology and Cancer Biology & Developmental Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Integrative Biology Graduate Training Program, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Key Laboratory of Birth Defects, Children's Hospital of Fudan University, 201102 Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2016.11.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600615PMC
January 2017

Functional significance of the sex chromosomes during spermatogenesis.

Reproduction 2015 Jun;149(6):R265-77

Division of Developmental BiologyDivision of Reproductive SciencesCincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA Division of Developmental BiologyDivision of Reproductive SciencesCincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA

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http://dx.doi.org/10.1530/REP-14-0613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510947PMC
June 2015

Licensing of primordial germ cells for gametogenesis depends on genital ridge signaling.

PLoS Genet 2015 Mar 4;11(3):e1005019. Epub 2015 Mar 4.

Whitehead Institute, Cambridge, Massachusetts, United States of America; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Howard Hughes Medical Institute, Whitehead Institute, Cambridge, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349450PMC
March 2015

Retinoic acid activates two pathways required for meiosis in mice.

PLoS Genet 2014 Aug 7;10(8):e1004541. Epub 2014 Aug 7.

Whitehead Institute, Cambridge, Massachusetts, United States of America; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Howard Hughes Medical Institute, Whitehead Institute, Cambridge, Massachusetts, United States of America.

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http://pagelab.wi.mit.edu/pdf/2014-Koubova.pdf
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http://dx.plos.org/10.1371/journal.pgen.1004541
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http://dx.doi.org/10.1371/journal.pgen.1004541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125102PMC
August 2014

Gata4 is required for formation of the genital ridge in mice.

PLoS Genet 2013 11;9(7):e1003629. Epub 2013 Jul 11.

Whitehead Institute, Howard Hughes Medical Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1371/journal.pgen.1003629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708810PMC
January 2014

Tumor suppressor gene Rb is required for self-renewal of spermatogonial stem cells in mice.

Proc Natl Acad Sci U S A 2013 Jul 15;110(31):12685-90. Epub 2013 Jul 15.

Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1073/pnas.1311548110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732951PMC
July 2013

Licensing of gametogenesis, dependent on RNA binding protein DAZL, as a gateway to sexual differentiation of fetal germ cells.

Proc Natl Acad Sci U S A 2011 May 19;108(18):7443-8. Epub 2011 Apr 19.

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1073/pnas.1104501108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088606PMC
May 2011

Loss of YY1 impacts the heterochromatic state and meiotic double-strand breaks during mouse spermatogenesis.

Mol Cell Biol 2009 Dec 28;29(23):6245-56. Epub 2009 Sep 28.

Department of Pathology, Harvard Medical School, New Research Building 854b, Boston, MA 02115, USA.

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http://dx.doi.org/10.1128/MCB.00679-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786691PMC
December 2009

Promotion of bladder cancer development and progression by androgen receptor signals.

J Natl Cancer Inst 2007 Apr;99(7):558-68

Department of Pathology, University of Rochester Medical Center, 601 Elmwood Ave, Box 626, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1093/jnci/djk113DOI Listing
April 2007

In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replication.

Nat Genet 2006 Dec 19;38(12):1430-4. Epub 2006 Nov 19.

Howard Hughes Medical Institute, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/ng1919DOI Listing
December 2006

Inhibition of lung tumor growth and augmentation of radiosensitivity by decreasing peroxiredoxin I expression.

Int J Radiat Oncol Biol Phys 2006 Feb;64(2):581-91

Department of Radiation Oncology, Chang Gung Memorial Hospital, and Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.ijrobp.2005.10.012DOI Listing
February 2006

Induction of androgen receptor expression by phosphatidylinositol 3-kinase/Akt downstream substrate, FOXO3a, and their roles in apoptosis of LNCaP prostate cancer cells.

J Biol Chem 2005 Sep 1;280(39):33558-65. Epub 2005 Aug 1.

George Whipple Laboratory for Cancer Research, Department of Pathology, The Cancer Center, University of Rochester, Rochester, New York 14642, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M504461200
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http://dx.doi.org/10.1074/jbc.M504461200DOI Listing
September 2005

Regulation of androgen receptor signaling by PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor through distinct mechanisms in prostate cancer cells.

Mol Endocrinol 2004 Oct 17;18(10):2409-23. Epub 2004 Jun 17.

George Whipple Laboratory for Cancer Research, Department of Urology, The Cancer Center, University of Rochester, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1210/me.2004-0117DOI Listing
October 2004

Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer.

J Biol Chem 2004 Aug 27;279(32):33438-46. Epub 2004 May 27.

George Whipple Laboratory for Cancer Research, Department of Pathology, University of Rochester, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1074/jbc.M401781200DOI Listing
August 2004

Subfertility and defective folliculogenesis in female mice lacking androgen receptor.

Proc Natl Acad Sci U S A 2004 Aug 26;101(31):11209-14. Epub 2004 Jul 26.

George Whipple Laboratory for Cancer Research, Departments of Pathology and Urology, University of Rochester, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1073/pnas.0404372101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC509185PMC
August 2004

Nongenomic androgen activation of phosphatidylinositol 3-kinase/Akt signaling pathway in MC3T3-E1 osteoblasts.

J Bone Miner Res 2004 Jul 8;19(7):1181-90. Epub 2004 Mar 8.

The Center for Menopause and Reproductive Medicine Research, Chang Gung University/Memorial Hospital, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1359/JBMR.040306DOI Listing
July 2004

Suppression of androgen receptor-mediated transactivation and cell growth by the glycogen synthase kinase 3 beta in prostate cells.

J Biol Chem 2004 Jul 3;279(31):32444-52. Epub 2004 Jun 3.

George Whipple Laboratory for Cancer Research, Department of Pathology, University of Rochester Medical Center, New York 14642, USA.

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http://dx.doi.org/10.1074/jbc.M313963200DOI Listing
July 2004

Actin monomer enhances supervillin-modulated androgen receptor transactivation.

Biochem Biophys Res Commun 2004 Jun;319(2):393-6

George Whipple Cancer Research Laboratory, University of Rochester Medical Center, 601 Elmwood Ave., Rochester, NY 14642, USA.

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http://dx.doi.org/10.1016/j.bbrc.2004.04.186DOI Listing
June 2004

Androgen signaling is required for the vitamin D-mediated growth inhibition in human prostate cancer cells.

Oncogene 2004 Apr;23(19):3350-60

Department of Urology, University of Rochester, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1038/sj.onc.1207461DOI Listing
April 2004

Androgen suppresses PML protein expression in prostate cancer CWR22R cells.

Biochem Biophys Res Commun 2004 Jan;314(1):69-75

George Whipple Lab for Cancer Research, Department of Pathology, The Cancer Center, University of Rochester Medical Center, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1016/j.bbrc.2003.12.060DOI Listing
January 2004

Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers.

J Biol Chem 2003 Dec 10;278(51):50902-7. Epub 2003 Oct 10.

George Whipple Laboratory for Cancer Research, Department of Pathology, and The Cancer Center, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1074/jbc.M300676200DOI Listing
December 2003

Disruption of TR4 orphan nuclear receptor reduces the expression of liver apolipoprotein E/C-I/C-II gene cluster.

J Biol Chem 2003 Nov 3;278(47):46919-26. Epub 2003 Sep 3.

George Whipple Laboratory for Cancer Research, University of Rochester Medical Center, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1074/jbc.M304088200DOI Listing
November 2003

The use of phage display technique for the isolation of androgen receptor interacting peptides with (F/W)XXL(F/W) and FXXLY new signature motifs.

J Biol Chem 2003 Jun 24;278(26):23691-8. Epub 2003 Apr 24.

Department of Pathology, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1074/jbc.M211908200DOI Listing
June 2003

Suppression of estrogen receptor-mediated transcription and cell growth by interaction with TR2 orphan receptor.

J Biol Chem 2002 Sep 1;277(37):33571-9. Epub 2002 Jul 1.

George Whipple Laboratory for Cancer Research, Department of Pathology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M203531200
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http://dx.doi.org/10.1074/jbc.M203531200DOI Listing
September 2002

Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase.

EMBO J 2002 Aug;21(15):4037-48

George H.Whipple Laboratory for Cancer Research, Department of Pathology and The Cancer Center, University of Rochester, Rochester, NY 14642, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC126152PMC
http://dx.doi.org/10.1093/emboj/cdf406DOI Listing
August 2002

Modulation of estrogen receptor-mediated transactivation by orphan receptor TR4 in MCF-7 cells.

J Biol Chem 2002 Apr 13;277(17):14622-8. Epub 2002 Feb 13.

George Whipple Laboratory for Cancer Research, Department of Pathology, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1074/jbc.M110051200DOI Listing
April 2002