Am J Med 2022 May 15. Epub 2022 May 15.
Division of Nephrology, Nanfang Hospital, Southern Medical University; National Clinical Research Center for Kidney Disease; State Key Laboratory of Organ Failure Research; Guangdong Provincial Institute of Nephrology, Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou Regenerative Medicine and Health Guangdong Laboratory; Guangdong Provincial Clinical Research Center for Kidney Disease, Guangzhou, China; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Institute of Biomedicine, Anhui Medical University, Hefei 230032, China. Electronic address:
Background: The association between domestic physical activity and the risk of hypertension remains uncertain. We aimed to evaluate the prospective relation of domestic physical activity and new-onset hypertension among Chinese males and females.
Methods: A total of 9254 adults who were free of hypertension at baseline were enrolled from the China Health and Nutrition Survey (CHNS). Data on domestic physical activity were obtained by using self-reported questionnaires, and calculated as metabolic equivalent task (MET)-hours/week. MET-hours/week may account for both intensity and time spent on activities. The study outcome was new-onset hypertension, defined as systolic blood pressure ≥140mmHg or diastolic blood pressure ≥90mmHg or diagnosed by physician or under antihypertensive treatment during the follow-up.
Results: During a median of 8.0 years (81,996 person-years) of follow-up, a total of 2892 participants developed hypertension. Overall, there were reversed J-shaped associations between the domestic physical activity and new-onset hypertension in both males and females (both P values for nonlinearity<0.001). Consistently, when domestic physical activity was assessed as categories (<10, 10-<20, 20-<30, 30-<40, 40-<50, 50-<60, 60-<70, 70-<80, 80-<90, 90-<100, ≥100 MET-hours/week), compared with those with domestic physical activity <10 MET-hours/week, the lower and similar risks of new-onset hypertension were found in participants with domestic physical activity 30-<90 MET-hours/week in both males and females.
Conclusion: Moderate domestic physical activity was associated with a lower risk of new-onset hypertension among both males and females.