Publications by authors named "Yuan-Hao Fu"

3 Publications

  • Page 1 of 1

Simulation Training in Minimally Invasive Direct Coronary Artery Bypass Grafting.

Heart Surg Forum 2020 Oct 16;23(6):E774-E780. Epub 2020 Oct 16.

Cardiac Surgery Department, Peking University Third Hospital, Beijing, P.R. China.

Background: To evaluate the effect of minimally invasive direct coronary artery bypass (MIDCAB) simulator for cardiac residency training.

Methods: A total of 26 resident surgeons who had never trained for coronary artery anastomosis participated in this training program. They received coronary artery anastomosis training on off-pump coronary artery bypass grafting (OPCAB) simulator for 15 h. After training, their performance of anastomosis was evaluated on the OPCAB simulator according to 12 items and a 5-point global rating scale. Based on the total score of assessment, those with an individual score of 12-36 formed group A, while group B was composed of the remaining trainees. The two groups then received another 15 h coronary artery anastomosis training on the MIDCAB simulator, and the performance was assessed.

Results: Trainees improved their performance of coronary artery anastomosis after training on the OPCAB simulator. Group A was composed of 7 trainees with an individual with a total score of 12-36 points and group B was composed of the remaining 19 trainees. After MIDCAB simulator training, significant differences were noted in the pre- and post-training values in the A group (P < .001), and the assessment value of group A was significantly better than those of group B (P < .05). No significant difference was detected between pre- and post-training values in group B after MIDCAB simulator training (P > .05).

Conclusion: We concluded that trainees who performed well in OPCAB simulation training can also perform better in MIDCAB, and our designed MIDCAB simulator was useful for residency training.
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http://dx.doi.org/10.1532/hsf.3185DOI Listing
October 2020

Identification of Vinculin as a Potential Diagnostic Biomarker for Acute Aortic Dissection Using Label-Free Proteomics.

Biomed Res Int 2020 19;2020:7806409. Epub 2020 Jul 19.

Department of Cardiac Surgery, Peking University Third Hospital, Beijing 100191, China.

Acute aortic dissection (AAD) is an emergent vascular disease. Currently, its diagnosis depends on clinical and radiological investigations but lacking of serum biomarkers. In this study, we aimed to identify potential serum biomarkers for AAD using label-free proteomics approach. A total of 90 serum samples were collected from three groups: patients with acute aortic dissection (AAD, = 30), patients with acute myocardial infarction (AMI, = 30), and healthy controls ( = 30), and the first four samples from each group were selected for label-free proteomics analysis. Using label-free approach, a total of 22 differentially expressed proteins were identified in the serum samples of the AAD group, of which 15 were upregulated and 7 were downregulated as compared to the AMI and healthy control groups. The most prominent increased protein was vinculin, which was selected to validate in total samples. The level of vinculin was significantly elevated in AAD patients (15.8 ng/ml, IQR: 9.3-19.9 ng/ml) than that in AMI patients (8.6 ng/ml, IQR:5.3-11.4 ng/ml) and healthy volunteers (5.3 ng/ml, IQR:2.8-7.6 ng/ml), < 0.0001. Furthermore, the concentration of vinculin both increased in type A and B dissection. At the early stage of AAD, vinculin maintained a high level to 48 hours compared with that of AMI. Our study demonstrated that vinculin may play a role in the early diagnosis of AAD.
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http://dx.doi.org/10.1155/2020/7806409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388002PMC
May 2021

A Huge Congenital Left Atrial Appendage Aneurysm.

Chin Med J (Engl) 2017 Dec;130(24):3011-3012

Department of Cardiac Surgery, Peking University Third Hospital, Beijing 100191, China.

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http://dx.doi.org/10.4103/0366-6999.220301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742935PMC
December 2017
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