Dr. Yu-Fen Lin, PhD - UT Southwestern Medical Center at Dallas - Instructor

Dr. Yu-Fen Lin

PhD

UT Southwestern Medical Center at Dallas

Instructor

Dallas, TX | United States

Main Specialties: Biology

Additional Specialties: Radiation Biology, Cell Biology, Biochemistry, Proteomics

Dr. Yu-Fen Lin, PhD - UT Southwestern Medical Center at Dallas - Instructor

Dr. Yu-Fen Lin

PhD

Introduction

Primary Affiliation: UT Southwestern Medical Center at Dallas - Dallas, TX , United States

Specialties:

Additional Specialties:

Publications

15Publications

442Reads

-Profile Views

260PubMed Central Citations

The catalytic subunit of DNA-dependent protein kinase is required for cellular resistance to oxidative stress independent of DNA double-strand break repair.

Free Radic Biol Med 2014 Nov 16;76:278-85. Epub 2014 Sep 16.

Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267055PMC
November 2014
66 Reads
7 Citations
5.740 Impact Factor

DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response.

Nucleic Acids Res 2014 Apr 5;42(7):4463-73. Epub 2014 Feb 5.

Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas, Southwestern Medical Center at Dallas, Dallas, TX 75390, USA and Division of Molecular Pharmacology, Department of Pathophysiological and Therapeutic Science, Tottori University, Japan.

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http://dx.doi.org/10.1093/nar/gku116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985680PMC
April 2014
12 Reads
10 Citations
9.112 Impact Factor

MicroRNA-449a enhances radiosensitivity in CL1-0 lung adenocarcinoma cells.

PLoS One 2013 17;8(4):e62383. Epub 2013 Apr 17.

Graduate Institute of Physiology, National Taiwan University, Taipei, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062383PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629161PMC
November 2013
35 Reads
11 Citations
3.234 Impact Factor

A method for systematic mapping of protein lysine methylation identifies functions for HP1β in DNA damage response.

Mol Cell 2013 Jun 23;50(5):723-35. Epub 2013 May 23.

Department of Biochemistry and the Siebens-Drake Medical Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON N6A 5C1, Canada.

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http://dx.doi.org/10.1016/j.molcel.2013.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032624PMC
June 2013
35 Reads
29 Citations
14.020 Impact Factor

Threonine 2609 phosphorylation of the DNA-dependent protein kinase is a critical prerequisite for epidermal growth factor receptor-mediated radiation resistance.

Mol Cancer Res 2012 Oct 23;10(10):1359-68. Epub 2012 Aug 23.

Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-12-0482-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475795PMC
October 2012
14 Reads
9 Citations
4.380 Impact Factor

Akt promotes post-irradiation survival of human tumor cells through initiation, progression, and termination of DNA-PKcs-dependent DNA double-strand break repair.

Mol Cancer Res 2012 Jul 17;10(7):945-57. Epub 2012 May 17.

Division of Radiobiology and Molecular Environmental Research, Department of Radiation Oncology, Eberhard Karls University Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1158/1541-7786.MCR-11-0592DOI Listing
July 2012
38 Reads
36 Citations
4.380 Impact Factor

Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair.

J Cell Biol 2011 Apr 11;193(2):295-305. Epub 2011 Apr 11.

Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1083/jcb.201009074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080267PMC
April 2011
49 Reads
53 Citations
9.834 Impact Factor

Involvement of DNA-dependent protein kinase in normal cell cycle progression through mitosis.

J Biol Chem 2011 Apr 17;286(14):12796-802. Epub 2011 Feb 17.

Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1074/jbc.M110.212969DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069479PMC
April 2011
21 Reads
28 Citations
4.573 Impact Factor

Differential role of DNA-PKcs phosphorylations and kinase activity in radiosensitivity and chromosomal instability.

Radiat Res 2011 Jan 17;175(1):83-9. Epub 2010 Nov 17.

Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado 80523, USA.

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http://dx.doi.org/10.1667/RR2092.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073160PMC
January 2011
8 Reads
13 Citations
2.911 Impact Factor

Comparison of several radiation effects in human MCF10A mammary epithelial cells cultured as 2D monolayers or 3D acinar stuctures in matrigel.

Radiat Res 2009 Jun;171(6):708-15

Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado 80523, USA.

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http://dx.doi.org/10.1667/RR1554.1DOI Listing
June 2009
21 Reads
7 Citations
2.911 Impact Factor

Secretome analysis of novel IgE-binding proteins from Penicillium citrinum.

Proteomics Clin Appl 2008 Jan 11;2(1):33-45. Epub 2007 Dec 11.

Graduate Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1002/prca.200780050DOI Listing
January 2008
41 Reads
7 Citations
2.683 Impact Factor

Duodenal ulcer-related antigens from Helicobacter pylori: immunoproteome and protein microarray approaches.

Mol Cell Proteomics 2007 Jun 21;6(6):1018-26. Epub 2007 Feb 21.

Graduate Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.

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http://dx.doi.org/10.1074/mcp.M700009-MCP200DOI Listing
June 2007
11 Reads
4 Citations
6.564 Impact Factor

Comparative immunoproteomics of identification and characterization of virulence factors from Helicobacter pylori related to gastric cancer.

Mol Cell Proteomics 2006 Aug 11;5(8):1484-96. Epub 2006 Jun 11.

Graduate Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.

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http://dx.doi.org/10.1074/mcp.M600111-MCP200DOI Listing
August 2006
26 Reads
21 Citations
6.564 Impact Factor

Proteomics and immunological analysis of a novel shrimp allergen, Pen m 2.

J Immunol 2003 Jan;170(1):445-53

Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.4049/jimmunol.170.1.445DOI Listing
January 2003
29 Reads
20 Citations
4.922 Impact Factor

Top co-authors

David J Chen
David J Chen

University of Texas Southwestern Medical Center

5
Lu-Ping Chow
Lu-Ping Chow

College of Medicine

4
Joel S Bedford
Joel S Bedford

Colorado State University

3
Hatsumi Nagasawa
Hatsumi Nagasawa

Colorado State University

3
Eric Y Chuang
Eric Y Chuang

National Taiwan University

3
Benjamin P Chen
Benjamin P Chen

University of Texas Southwestern Medical Center

2
Yuanlin Peng
Yuanlin Peng

Colorado State University

2
Mong-Hsun Tsai
Mong-Hsun Tsai

National Taiwan University

2