Publications by authors named "Yu-Chih Liu"

89Publications

HDAC1 dysregulation induces aberrant cell cycle and DNA damage in progress of TDP-43 proteinopathies.

EMBO Mol Med 2020 Jun 25;12(6):e10622. Epub 2020 May 25.

Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

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http://dx.doi.org/10.15252/emmm.201910622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278561PMC
June 2020

The cancer control status and APACHE II score are prognostic factors for critically ill patients with cancer and sepsis.

J Formos Med Assoc 2020 Jan 30;119(1 Pt 2):276-281. Epub 2019 May 30.

Division of Pulmonary, Critical Care, and Sleep Medicine Chang Gung Memorial Hospital, Keelung, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.jfma.2019.05.012DOI Listing
January 2020

Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening.

Bioorg Chem 2019 05 28;86:494-500. Epub 2019 Jan 28.

State Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China; School of Life Science and Technology, ShanghaiTech University, 100 Haike Road, Shanghai 201210, China; Open Studio for Druggability Research of Marine Natural Products, Pilot National Laboratory for Marine Science and Technology (Qingdao), 1 Wenhai Road, Aoshanwei, Jimo, Qingdao 266237, China. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.01.035DOI Listing
May 2019

Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors.

Bioorg Med Chem 2018 11 27;26(20):5397-5407. Epub 2018 Jul 27.

State Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China; Open Studio for Druggability Research of Marine Natural Products, Pilot National Laboratory for Marine Science and Technology (Qingdao), 1 Wenhai Road, Aoshanwei, Jimo, Qingdao 266237, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680896183114
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http://dx.doi.org/10.1016/j.bmc.2018.07.048DOI Listing
November 2018

Identification of novel inhibitors of histone acetyltransferase hMOF through high throughput screening.

Eur J Med Chem 2018 Sep 17;157:867-876. Epub 2018 Aug 17.

State Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.08.026DOI Listing
September 2018

C6orf106 is a novel inhibitor of the interferon-regulatory factor 3-dependent innate antiviral response.

J Biol Chem 2018 07 25;293(27):10561-10573. Epub 2018 May 25.

From the Australian Animal Health Laboratory, Commonwealth Scientific and Industrial Research Organisation (CSIRO) Health and Biosecurity, Geelong, Victoria 3220, Australia and

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http://dx.doi.org/10.1074/jbc.RA117.001491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036214PMC
July 2018

Discovery of 1,8-acridinedione derivatives as novel GCN5 inhibitors via high throughput screening.

Eur J Med Chem 2018 May 14;151:740-751. Epub 2018 Feb 14.

Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234183012
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http://dx.doi.org/10.1016/j.ejmech.2018.02.005DOI Listing
May 2018

Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay.

Bioorg Med Chem 2018 05 24;26(8):1751-1758. Epub 2018 Feb 24.

Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2018.02.020DOI Listing
May 2018

Design, synthesis and biological activity of 4-(4-benzyloxy)phenoxypiperidines as selective and reversible LSD1 inhibitors.

Bioorg Chem 2018 08 16;78:7-16. Epub 2018 Feb 16.

Department of Pharmaceutical Engineering & Department of Biochemical Engineering, 639 Longmian Avenue, Nanjing 211198, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2018.02.016DOI Listing
August 2018

Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1.

ACS Chem Biol 2018 03 8;13(3):772-781. Epub 2018 Feb 8.

Drug Discovery and Design Center, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research , Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203 , China.

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http://dx.doi.org/10.1021/acschembio.7b00890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913882PMC
March 2018

Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation.

J Med Chem 2017 11 27;60(21):8888-8905. Epub 2017 Oct 27.

Drug Discovery and Design Center, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , 555 Zuchongzhi Road, Shanghai 201203, China.

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http://dx.doi.org/10.1021/acs.jmedchem.7b01134DOI Listing
November 2017

A microfluidics-based mobility shift assay to identify new inhibitors of β-secretase for Alzheimer's disease.

Anal Bioanal Chem 2017 Nov 9;409(28):6635-6642. Epub 2017 Sep 9.

State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China.

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http://dx.doi.org/10.1007/s00216-017-0617-yDOI Listing
November 2017

Machine-Learning-Assisted Approach for Discovering Novel Inhibitors Targeting Bromodomain-Containing Protein 4.

J Chem Inf Model 2017 07 10;57(7):1677-1690. Epub 2017 Jul 10.

Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , 555 Zuchongzhi Road, Shanghai 201203, China.

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http://dx.doi.org/10.1021/acs.jcim.7b00098DOI Listing
July 2017

Design and optimization of purine derivatives as in vivo active PDE10A inhibitors.

Bioorg Med Chem 2017 07 13;25(13):3315-3329. Epub 2017 Apr 13.

Department of Medicinal Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.04.019DOI Listing
July 2017

Design, synthesis and biological activity of 3-oxoamino-benzenesulfonamides as selective and reversible LSD1 inhibitors.

Bioorg Chem 2017 06 13;72:182-189. Epub 2017 Apr 13.

Jiangsu Key Laboratory of Drug Screening, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China; Department of Biochemical Engineering, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2017.04.006DOI Listing
June 2017

Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening.

Org Biomol Chem 2017 May;15(17):3648-3661

Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.

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http://dx.doi.org/10.1039/c7ob00070gDOI Listing
May 2017

Marine-derived chromopeptide A, a novel class I HDAC inhibitor, suppresses human prostate cancer cell proliferation and migration.

Acta Pharmacol Sin 2017 Apr 23;38(4):551-560. Epub 2017 Jan 23.

Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

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http://dx.doi.org/10.1038/aps.2016.139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386309PMC
April 2017

Discovery of novel DNA methyltransferase 3A inhibitors via structure-based virtual screening and biological assays.

Bioorg Med Chem Lett 2017 01 11;27(2):342-346. Epub 2016 Nov 11.

Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of MateriaMedica, Chinese Academy of Sciences, Shanghai 201203, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.11.023DOI Listing
January 2017

Discovery of Novel Inhibitors Targeting the Menin-Mixed Lineage Leukemia Interface Using Pharmacophore- and Docking-Based Virtual Screening.

J Chem Inf Model 2016 09 24;56(9):1847-55. Epub 2016 Aug 24.

Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , 555 Zuchongzhi Road, Shanghai 201203, China.

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http://dx.doi.org/10.1021/acs.jcim.6b00185DOI Listing
September 2016

Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays.

Bioorg Med Chem Lett 2016 08 30;26(15):3813-7. Epub 2016 May 30.

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai 201203, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.05.018DOI Listing
August 2016

Identification of subclinical transmission of vancomycin-resistant enterococcus within an intensive care unit in Taiwan.

J Microbiol Immunol Infect 2016 Oct 18;49(5):749-759. Epub 2016 Jan 18.

Department of Chest, Chang Gung Memorial Hospital, Keelung, and Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan.

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http://dx.doi.org/10.1016/j.jmii.2015.11.002DOI Listing
October 2016

Liver Cirrhosis and Diabetes Mellitus Are Risk Factors for Staphylococcus aureus Infection in Patients with Healthcare-Associated or Hospital-Acquired Pneumonia.

Pulm Med 2016 22;2016:4706150. Epub 2016 Feb 22.

Division of Pulmonary, Critical Care and Sleep Medicine, Chang Gung Memorial Hospital, 222 Maijin Road, Anle District, Keelung 20401, Taiwan; Chang Gung University College of Medicine, Taoyuan, Taiwan.

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http://dx.doi.org/10.1155/2016/4706150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779838PMC
October 2016

Identification of Novel Disruptor of Telomeric Silencing 1-like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays.

J Chem Inf Model 2016 Mar 4;56(3):527-34. Epub 2016 Mar 4.

Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , 555 Zu Chongzhi Road, Shanghai 201203, China.

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http://dx.doi.org/10.1021/acs.jcim.5b00738DOI Listing
March 2016

Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors.

Bioorg Med Chem Lett 2016 Feb 7;26(3):721-725. Epub 2016 Jan 7.

Department of Medicinal Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.01.006DOI Listing
February 2016

Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening.

J Med Chem 2015 Oct 30;58(20):8166-81. Epub 2015 Sep 30.

Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

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http://dx.doi.org/10.1021/acs.jmedchem.5b01154DOI Listing
October 2015

Effect of interleukin-17 on in vitro cytokine production in healthy controls and patients with severe sepsis.

J Formos Med Assoc 2015 Dec 28;114(12):1250-7. Epub 2015 Jan 28.

Department of Chemistry, National Chung-Hsing University, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jfma.2014.09.009DOI Listing
December 2015

Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization.

J Med Chem 2015 Feb 14;58(3):1281-97. Epub 2015 Jan 14.

Department of Medicinal Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, ‡Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, and §Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , 555 Zuchongzhi Road, Shanghai 201203, China.

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http://pubs.acs.org/doi/10.1021/jm501504k
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http://dx.doi.org/10.1021/jm501504kDOI Listing
February 2015

Expression, refolding, purification and crystallization of the sensory domain of the TlpC chemoreceptor from Helicobacter pylori for structural studies.

Protein Expr Purif 2015 Mar 21;107:29-34. Epub 2014 Nov 21.

Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pep.2014.11.003DOI Listing
March 2015

Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening.

J Med Chem 2014 Nov 4;57(21):9028-41. Epub 2014 Nov 4.

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.

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http://dx.doi.org/10.1021/jm501134eDOI Listing
November 2014

Comparison of cardiovascular co-morbidities and CPAP use in patients with positional and non-positional mild obstructive sleep apnea.

BMC Pulm Med 2014 Sep 26;14:153. Epub 2014 Sep 26.

Division of Pulmonary Medicine, Department of Internal Medicine, Taipei Tzuchi Hospital, the Buddhist Tzuchi Medical Foundation, Xindian Dist, New Taipei City, Taiwan.

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http://dx.doi.org/10.1186/1471-2466-14-153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189203PMC
September 2014

Chemical proteomics identifies heterogeneous nuclear ribonucleoprotein (hnRNP) A1 as the molecular target of quercetin in its anti-cancer effects in PC-3 cells.

J Biol Chem 2014 Aug 24;289(32):22078-89. Epub 2014 Jun 24.

From the Graduate Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei 100, Taiwan and

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http://www.jbc.org/lookup/doi/10.1074/jbc.M114.553248
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http://dx.doi.org/10.1074/jbc.M114.553248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139222PMC
August 2014

Ergoline-derived inverse agonists of the human h3 receptor for the treatment of narcolepsy.

ChemMedChem 2014 Aug 21;9(8):1683-96. Epub 2014 May 21.

Novartis Institutes for BioMedical Research, Forum 1, Novartis Campus, 4056 Basel (Switzerland).

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http://dx.doi.org/10.1002/cmdc.201402055DOI Listing
August 2014

A molecular basis for the interplay between T cells, viral mutants, and human leukocyte antigen micropolymorphism.

J Biol Chem 2014 Jun 23;289(24):16688-98. Epub 2014 Apr 23.

From the Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Melbourne 3800, Australia, Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria 3800, Australia

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http://dx.doi.org/10.1074/jbc.M114.563502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059114PMC
June 2014

Elevated circulating levels of tissue factor-positive microvesicles are associated with distant metastasis in lung cancer.

J Cancer Res Clin Oncol 2014 Jan 30;140(1):61-7. Epub 2013 Oct 30.

Department of Internal Medicine, Chang Gung Memory Hospital, Keelung, Taiwan, ROC.

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http://link.springer.com/10.1007/s00432-013-1544-8
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http://dx.doi.org/10.1007/s00432-013-1544-8DOI Listing
January 2014

Disease animal models of TDP-43 proteinopathy and their pre-clinical applications.

Int J Mol Sci 2013 Oct 9;14(10):20079-111. Epub 2013 Oct 9.

Institute of Clinical Medicine, National Cheng Kung University, Tainan 704, Taiwan.

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http://dx.doi.org/10.3390/ijms141020079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821604PMC
October 2013

Associations of T helper 1, 2, 17 and regulatory T lymphocytes with mortality in severe sepsis.

Inflamm Res 2013 Aug 14;62(8):751-63. Epub 2013 May 14.

Division of Pulmonary, Critical Care and Sleep Medicine, Chang Gung Memorial Hospital, Keelung 204, Taiwan ROC.

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http://dx.doi.org/10.1007/s00011-013-0630-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712133PMC
August 2013

Psychometric properties of the Chinese version of Strength and Difficulties Questionnaire.

Compr Psychiatry 2013 Aug 20;54(6):720-30. Epub 2013 Feb 20.

Department of Child and Adolescent Psychiatry, Taoyuan Mental Hospital, Tao-Yuan, Taiwan.

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http://dx.doi.org/10.1016/j.comppsych.2013.01.002DOI Listing
August 2013

Factors affecting CPAP acceptance in elderly patients with obstructive sleep apnea in Taiwan.

Respir Care 2013 Sep 19;58(9):1504-13. Epub 2013 Feb 19.

Division of Pulmonary and Critical Care Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.

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http://dx.doi.org/10.4187/respcare.02176DOI Listing
September 2013

Comparison of respiratory parameters and plasma cytokine levels between treatment with Salmeterol/fluticasone and ipratropium/terbutaline/budesonide in mechanically ventilated COPD patients.

Chang Gung Med J 2012 Sep-Oct;35(5):373-81

Division of Pulmonary, Critical Care and Sleep Medicine, Chang Gung Memorial Hospital at Keelung, Chang Gung University College of Medicine, Taoyuan, Taiwan.

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http://dx.doi.org/10.4103/2319-4170.105481DOI Listing
November 2013

Images in emergency medicine. A suddenly collapsed man. Neurogenic pulmonary edema.

Ann Emerg Med 2012 Oct;60(4):535, 541

Department of Surgery, Tainan Hospital, Department of Health, Executive Yuan, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.annemergmed.2012.03.033DOI Listing
October 2012

Endogenous antigen presentation impacts on T-box transcription factor expression and functional maturation of CD8+ T cells.

Blood 2012 Oct 31;120(16):3237-45. Epub 2012 Aug 31.

Australian Centre for Vaccine Development and Tumour Immunology Laboratory, Department of Immunology, Queensland Institute of Medical Research, Brisbane, Australia.

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http://www.bloodjournal.org/content/early/2012/08/31/blood-2
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2012-03-42
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http://dx.doi.org/10.1182/blood-2012-03-420182DOI Listing
October 2012

Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43.

Proc Natl Acad Sci U S A 2012 Sep 29;109(37):15024-9. Epub 2012 Aug 29.

Institute of Life Science, National Defense Medical Center, Taipei, Taiwan 11490.

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http://dx.doi.org/10.1073/pnas.1206362109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443184PMC
September 2012

Images in emergency medicine. Woman with painful purpura. Propylthiouracil-related ANCA-positive vasculitis.

Ann Emerg Med 2012 Sep;60(3):260, 268

Department of Surgery, Tainan Hospital, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.annemergmed.2012.01.014DOI Listing
September 2012

Gossypiboma.

Dig Liver Dis 2012 Aug 29;44(8):e17. Epub 2012 Mar 29.

Department of Surgery, Tainan Hospital, Department of Health, Executive Yuan, Tainan, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.dld.2012.02.019DOI Listing
August 2012

Factors that affect the diagnostic yield of endobronchial ultrasonography-assisted transbronchial lung biopsy.

J Laparoendosc Adv Surg Tech A 2012 May 29;22(4):319-23. Epub 2012 Mar 29.

Division of Pulmonary, Critical Care, and Sleep Medicine, Chang Gung Memorial Hospital at Keelung, Keelung City, Taiwan.

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http://dx.doi.org/10.1089/lap.2012.0092DOI Listing
May 2012

The effects of heated humidifier in continuous positive airway pressure titration.

Sleep Breath 2013 Mar 4;17(1):133-8. Epub 2012 Feb 4.

Chang Gung Memorial Hospital, Keelung, Taiwan, Republic of China.

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http://dx.doi.org/10.1007/s11325-012-0661-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575558PMC
March 2013

A structural basis for varied αβ TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule.

J Immunol 2012 Jan 2;188(1):311-21. Epub 2011 Dec 2.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.4049/jimmunol.1102686DOI Listing
January 2012

Autonomic activity difference during continuous positive airway pressure titration in patients with obstructive sleep apnea/hypopnea syndrome with or without hypertension.

Chang Gung Med J 2011 Jul-Aug;34(4):410-7

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Respiratory Therapy, Chang Gung Memorial Hospital at Keelung, Chang Gung University College of Medicine, Taoyuan, Taiwan.

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January 2012

Factors associated with in vitro interferon-gamma production in tuberculosis.

J Formos Med Assoc 2011 Apr;110(4):239-46

Division of Pulmonary Medicine, Chang Gung Memorial Hospital, Keelung, Chang Gung University College of Medicine, Taoyuan, Taiwan.

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http://dx.doi.org/10.1016/S0929-6646(11)60036-3DOI Listing
April 2011

Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.

Proc Natl Acad Sci U S A 2010 Jul 28;107(28):12599-604. Epub 2010 Jun 28.

Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1073/pnas.1007270107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906563PMC
July 2010

Functional haplotypes in the promoter region of transcription factor Nrf2 in chronic obstructive pulmonary disease.

Dis Markers 2010 ;28(3):185-93

Department of Internal Medicine, Chang Gung Memorial Hospital & Chang Gung University, Keelung, Taiwan.

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http://dx.doi.org/10.3233/DMA-2010-0700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833611PMC
September 2010

Comparing hydrocortisone and methylprednisolone in patients with septic shock.

Adv Ther 2009 Jul 23;26(7):728-35. Epub 2009 Jul 23.

Division of Pulmonary Medicine, Department of Internal Medicine & Department of Respiratory Therapy, Chang Gung Memorial Hospital, Keelung, Taiwan, Republic of China.

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http://dx.doi.org/10.1007/s12325-009-0043-4DOI Listing
July 2009

Augmentation of tendon-bone interface healing with low-intensity pulsed ultrasound.

Orthopedics 2009 Mar;32(3):173

Department of Orthopedic Surgery, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

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http://dx.doi.org/10.3928/01477447-20090301-19DOI Listing
March 2009

Serial cytokine levels in patients with severe sepsis.

Inflamm Res 2009 Jul 5;58(7):385-93. Epub 2009 Mar 5.

Division of Pulmonary Medicine, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung, #222, Maijin Rd. Anle Chiu, Keelung 204, Taiwan, ROC.

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http://dx.doi.org/10.1007/s00011-009-0003-0DOI Listing
July 2009

A long, naturally presented immunodominant epitope from NY-ESO-1 tumor antigen: implications for cancer vaccine design.

Cancer Res 2009 Feb 27;69(3):1046-54. Epub 2009 Jan 27.

Ludwig Institute for Cancer Research, Melbourne Centre for Clinical Sciences, Austin Health, Heidelberg, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2926DOI Listing
February 2009

The shaping of T cell receptor recognition by self-tolerance.

Immunity 2009 Feb 22;30(2):193-203. Epub 2009 Jan 22.

Department of Biochemistry and Molecular Biology, The Protein Crystallography Unit, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1016/j.immuni.2008.11.011DOI Listing
February 2009

Psychometric properties of the Chinese version of the Swanson, Nolan, and Pelham, Version IV Scale-Teacher Form.

J Pediatr Psychol 2009 Sep 12;34(8):850-61. Epub 2008 Dec 12.

Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1093/jpepsy/jsn133DOI Listing
September 2009

The interleukin-4 expression in patients with severe sepsis.

J Crit Care 2008 Dec;23(4):519-24

Division of Pulmonary Medicine, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung 204, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.jcrc.2007.11.008DOI Listing
December 2008

Effects of insulin and glucose on cytokine production from peripheral blood mononuclear cells.

Chang Gung Med J 2008 May-Jun;31(3):253-9

Division of Pulmonary Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan, ROC.

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October 2008

Pleural fluid viscosity may help identifying malignant pleural effusions.

Respirology 2008 May;13(3):341-5

Department of Pathology, Chang Gung Memorial Hospital and Chang Gung University, Keelung, Taiwan.

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http://dx.doi.org/10.1111/j.1440-1843.2008.01276.xDOI Listing
May 2008

Chiral separation of hydroxyflavanones in cyclodextrin-modified capillary zone electrophoresis using sulfated cyclodextrins as chiral selectors.

J Chromatogr A 2008 Apr 29;1188(2):301-7. Epub 2008 Feb 29.

Department of Applied Chemistry, Fooyin University, Ta-Liao, Kaohsiung County 831, Taiwan.

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http://dx.doi.org/10.1016/j.chroma.2008.02.074DOI Listing
April 2008

Psychometric properties of the Chinese version of the Swanson, Nolan, and Pelham, version IV scale - parent form.

Int J Methods Psychiatr Res 2008 ;17(1):35-44

Department of Psychiatry, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.1002/mpr.237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878250PMC
May 2008

Efficiency of interleukin-4 expression in patients with tuberculosis and nontubercular pneumonia.

Hum Immunol 2007 Oct 15;68(10):832-8. Epub 2007 Aug 15.

Division of Pulmonary Medicine, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan, Republic of China.

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http://dx.doi.org/10.1016/j.humimm.2007.07.003DOI Listing
October 2007

Enantioseparation of phenothiazines in CD-modified CZE using single isomer sulfated CD as a chiral selector.

Electrophoresis 2007 Nov;28(21):3922-9

Department of Chemistry, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1002/elps.200700059DOI Listing
November 2007

Gene polymorphisms of fibrinolytic enzymes in coal workers' pneumoconiosis.

Arch Environ Occup Health 2006 Mar-Apr;61(2):61-6

Department of Pathology, Chang Gung Memorial Hospital, Keelung and Chang Gung University, Keelung, Taiwan, Republic of China.

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http://dx.doi.org/10.3200/AEOH.61.2.61-66DOI Listing
August 2007

Ileocolon graft pedicled on ileocolic artery: an alternative esophageal substitute for corrosive injury.

Ann Thorac Surg 2007 Jul;84(1):295-6

Surgical Department, National Cheng-Kung University Hospital, Tainan, Taiwan.

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http://dx.doi.org/10.1016/j.athoracsur.2007.02.065DOI Listing
July 2007

Stem cell factor attenuates vascular smooth muscle apoptosis and increases intimal hyperplasia after vascular injury.

Arterioscler Thromb Vasc Biol 2007 Mar 4;27(3):540-7. Epub 2007 Jan 4.

Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, 222 Mai Chin Road, Keelung, Taiwan.

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https://www.ahajournals.org/doi/10.1161/01.ATV.0000257148.01
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http://dx.doi.org/10.1161/01.ATV.0000257148.01384.7dDOI Listing
March 2007

Identification of a novel competitive inhibitor of p38alpha MAPK by a human PBMC screen.

Biochem Biophys Res Commun 2007 Jan 27;352(3):656-61. Epub 2006 Nov 27.

Graduate Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.

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http://dx.doi.org/10.1016/j.bbrc.2006.11.069DOI Listing
January 2007

Conservative treatment for a symptomatic solitary ganglion cyst of the anterior meniscus invading into the infrapatellar fat pad.

Knee Surg Sports Traumatol Arthrosc 2007 Mar 18;15(3):220-4. Epub 2006 Aug 18.

Department of Orthopaedic Surgery, Mackay Memorial Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1007/s00167-006-0157-zDOI Listing
March 2007

Enantioseparation of phenothiazines in cyclodextrin-modified capillary zone electrophoresis using sulfated cyclodextrins as chiral selectors.

Electrophoresis 2005 Oct;26(20):3869-77

Department of Chemistry, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1002/elps.200500087DOI Listing
October 2005

Screening of drugs by FRET analysis identifies inhibitors of SARS-CoV 3CL protease.

Biochem Biophys Res Commun 2005 Jul;333(1):194-9

Graduate Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei.

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http://dx.doi.org/10.1016/j.bbrc.2005.05.095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092914PMC
July 2005

Enantioseparation of benzoins and enantiomer migration reversal of hydrobenzoin in capillary zone electrophoresis with dual cyclodextrin systems and borate complexation.

J Chromatogr A 2004 Apr;1032(1-2):227-35

Department of Chemistry, National Taiwan University, 1 Roosevelt Road Section 4, Taipei 10674, Taiwan.

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http://dx.doi.org/10.1016/j.chroma.2004.01.011DOI Listing
April 2004