Publications by authors named "Yu-Chen Chang"

77Publications

Demyelination Regulates the Circadian Transcription Factor BMAL1 to Signal Adult Neural Stem Cells to Initiate Oligodendrogenesis.

Cell Rep 2020 Nov;33(7):108394

Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China; Shenzhen Research Institute, City University of Hong Kong, Shenzhen, China. Electronic address:

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November 2020

Therapeutic Effects of BCG Vaccination on Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

J Diabetes Res 2020 26;2020:8954125. Epub 2020 Mar 26.

Department of Family Medicine, MacKay Memorial Hospital, No. 92, Section 2, Zhongshan North Road, Taipei City 10449, Taiwan.

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March 2020

Expedition to the missing link: Long noncoding RNAs in cardiovascular diseases.

J Biomed Sci 2020 Apr 2;27(1):48. Epub 2020 Apr 2.

Graduate Institute and Department of Pharmacology, National Taiwan University School of Medicine, No.1, Sec. 1, Ren-Ai Rd, 1150R, Taipei, Taiwan.

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April 2020

A field pilot-scale study on heavy metal-contaminated soil washing by using an environmentally friendly agent-poly-γ-glutamic acid (γ-PGA).

Environ Sci Pollut Res Int 2020 Oct 31;27(28):34760-34769. Epub 2019 Dec 31.

Department of Civil Engineering, National Chi Nan University, 1 Univ. Rd, Puli, Nantou 54561, Taiwan.

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October 2020

Therapeutic implications of circadian clocks in neurodegenerative diseases.

J Neurosci Res 2020 06 12;98(6):1095-1113. Epub 2019 Dec 12.

Department of Biomedical Sciences, City University of Hong Kong, Kowloon, Hong Kong.

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June 2020

Music Interventions for Anxiety in Pregnant Women: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

J Clin Med 2019 Nov 6;8(11). Epub 2019 Nov 6.

Department of Family Medicine, Hsinchu MacKay Memorial Hospital, No. 690, Section 2, Guangfu Road, East District, Hsinchu City 30071, Taiwan.

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November 2019

Comparisons of early and delayed abstainers and its effects on long-term smoking cessation in Taiwan.

Subst Abuse Treat Prev Policy 2019 08 14;14(1):31. Epub 2019 Aug 14.

The Department of Family Medicine, MacKay Memorial Hospital, No.92, Sec. 2, Zhongshan N. Rd., Zhongshan Dist, Taipei City, 104, Taiwan.

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August 2019

An acute decrease in plasma membrane tension induces macropinocytosis via PLD2 activation.

J Cell Sci 2019 09 2;132(17). Epub 2019 Sep 2.

Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei 10002, Taiwan

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September 2019

IgG4-Related Disease Presenting as Cervical Lymphadenopathy.

J Med Ultrasound 2019 Jan-Mar;27(1):43-46. Epub 2018 Oct 30.

Department of Otolaryngology, Far Eastern Memorial Hospital, Taipei, Taiwan.

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October 2018

Tks5 and Dynamin-2 enhance actin bundle rigidity in invadosomes to promote myoblast fusion.

J Cell Biol 2019 05 20;218(5):1670-1685. Epub 2019 Mar 20.

Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan

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May 2019

Factors associated with hospitalization for community-acquired pneumonia in home health care patients in Taiwan.

Aging Clin Exp Res 2020 Jan 14;32(1):149-155. Epub 2019 Mar 14.

The Department of Family Medicine, MacKay Memorial Hospital, No. 92, Sec. 2, Zhongshan N. Rd., Zhongshan Dist., Taipei, 104, Taiwan, ROC.

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January 2020

Dispersant-modified iron nanoparticles for mobility enhancement and TCE degradation: a comparison study.

Environ Sci Pollut Res Int 2019 Nov 19;26(33):34157-34166. Epub 2018 Nov 19.

Department of Civil Engineering, National Chi Nan University, 1 Univ. Rd, Puli, Nantou, 54561, Taiwan.

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November 2019

An atypical infection of the esophagus mimicking malignancy.

Gastrointest Endosc 2018 10 21;88(4):765-766. Epub 2018 Jun 21.

Department of Internal Medicine, Far Eastern Memorial Hospital, Ban-Ciao, New Taipei City, Taiwan, Republic of China; College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan, Republic of China.

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October 2018

Roles of posttherapy F-FDG PET/CT in patients with advanced squamous cell carcinoma of the uterine cervix receiving concurrent chemoradiotherapy.

Eur J Nucl Med Mol Imaging 2018 07 22;45(7):1197-1204. Epub 2018 Feb 22.

Gynecologic Cancer Research Center, Chang Gung Memorial Hospital at Linkou and Chang Gung University College of Medicine, Taoyuan, Taiwan.

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July 2018

Distance-saturation product of the 6-minute walk test predicts mortality of patients with non-cystic fibrosis bronchiectasis.

J Thorac Dis 2017 Sep;9(9):3168-3176

Department of Thoracic Medicine, Chang Gung Medical Foundation, Chang Gung University, College of Medicine, Taoyuan, Taiwan.

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September 2017

Endocrine mucin-producing sweat gland carcinoma with GATA3 expression: report of two cases.

Pathology 2017 Dec 25;49(7):805-808. Epub 2017 Oct 25.

Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:

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December 2017

Effects of different amounts of exercise on preventing depressive symptoms in community-dwelling older adults: a prospective cohort study in Taiwan.

BMJ Open 2017 05 2;7(4):e014256. Epub 2017 May 2.

Department of Public Health, National Cheng Kung University College of Medicine, Tainan, Taiwan.

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May 2017

Aerobic-synergized exercises may improve fall-related physical fitness in older adults.

J Sports Med Phys Fitness 2017 May;57(5):660-669

Department of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan -

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May 2017

The risk of carriage of spp. and in food animals in dynamic populations.

Vet Med Sci 2016 Nov 24;2(4):246-254. Epub 2016 Jun 24.

Department of Population Medicine and Diagnostic SciencesCornell UniversityIthaca NY14853.

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November 2016

Utility of (18)F-FDG PET/CT in patients with advanced squamous cell carcinoma of the uterine cervix receiving concurrent chemoradiotherapy: a parallel study of a prospective randomized trial.

Eur J Nucl Med Mol Imaging 2016 Sep 10;43(10):1812-23. Epub 2016 May 10.

Department of Nuclear Medicine and Molecular Imaging Center, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 5, Fu-Shin St., Gueishan Township, Taoyuan County, 33305, Taiwan.

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September 2016

Target disruption of ribosomal protein pNO40 accelerates aging and impairs osteogenic differentiation of mesenchymal stem cells.

Biochem Biophys Res Commun 2016 Jan 23;469(4):903-10. Epub 2015 Dec 23.

Department of Anatomy, College of Medicine, Chang Gung University, Taoyuan, Taiwan; Gene Engineered Mice Core Lab, Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan. Electronic address:

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January 2016

Levels of depressive symptoms may modify the relationship between the WHOQOL-BREF and its determining factors in community-dwelling older adults.

Int Psychogeriatr 2016 Apr 17;28(4):591-601. Epub 2015 Dec 17.

Department of Public Health,College of Medicine,National Cheng Kung University,Tainan,Taiwan.

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April 2016

Depression Affects the Scores of All Facets of the WHOQOL-BREF and May Mediate the Effects of Physical Disability among Community-Dwelling Older Adults.

PLoS One 2015 26;10(5):e0128356. Epub 2015 May 26.

Department of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Departments of Internal Medicine and Occuptional and Environmental Medicine, National Cheng Kung University, Tainan, Taiwan.

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April 2016

The Role of Pretreatment FDG-PET in Treating Cervical Cancer Patients With Enlarged Pelvic Lymph Node(s) Shown on MRI: A Phase 3 Randomized Trial With Long-Term Follow-Up.

Int J Radiat Oncol Biol Phys 2015 Jul 28;92(3):577-85. Epub 2015 Apr 28.

Department of Radiation Oncology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan; Department of Medical Imaging and Radiological Sciences, College of Medicine, Chang Gung University, Taiwan; Institute for Radiological Research, Chang Gung University and Chang Gung Memorial Hospital, Taiwan. Electronic address:

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July 2015

Protein binding reaction enhanced by bi-directional flow driven by on-chip thermopneumatic actuator.

Biomed Microdevices 2014 Apr;16(2):325-32

Graduate Institute of Medical Mechatronics, Chang Gung University, 259 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan, 333, Taiwan, Republic of China,

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April 2014

The role of the high-sensitivity C-reactive protein in patients with stable non-cystic fibrosis bronchiectasis.

Pulm Med 2013 7;2013:795140. Epub 2013 Dec 7.

Department of Thoracic Medicine, Chang Gung Medical Foundation, Department of Chest Medicine, Chang Gung University, College of Medicine, Taoyuan 33342, Taiwan.

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January 2014

The association between drinking habits and family relationships in 3 villages of indigenous Taiwanese.

Asia Pac J Public Health 2015 Mar 18;27(2):NP2721-31. Epub 2012 Jul 18.

China Medical University and Yang Ming University, Taipei, Taiwan

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March 2015

Centrosomal protein 55 (Cep55) stability is negatively regulated by p53 protein through Polo-like kinase 1 (Plk1).

J Biol Chem 2012 Feb 19;287(6):4376-85. Epub 2011 Dec 19.

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan 333.

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February 2012

Evaluation of novel fusion proteins derived from extracellular matrix binding domains of LigB as vaccine candidates against leptospirosis in a hamster model.

Vaccine 2011 Oct 29;29(43):7379-86. Epub 2011 Jul 29.

Department of Population medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, United States.

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October 2011

Effects of a community prevention intervention on public awareness, knowledge, and risk perception of club drug use by youth in Taiwan.

Subst Use Misuse 2011 27;46(10):1265-74. Epub 2011 May 27.

Department of Health Promotion and Health Education, National Taiwan Normal University, Taipei, Taiwan, Republic of China.

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December 2011

Associations between maternal phthalate exposure and cord sex hormones in human infants.

Chemosphere 2011 May 26;83(8):1192-9. Epub 2011 Jan 26.

Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.

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May 2011

Collection of in vivo-like liver cell secretome with alternative sample enrichment method using a hollow fiber bioreactor culture system combined with tangential flow filtration for secretomics analysis.

Anal Chim Acta 2011 Jan 5;684(1-2):72-9. Epub 2010 Nov 5.

Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

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January 2011

Age-dependent congener profiles of polychlorinated dibenzo-p-dioxins and dibenzofurans in the general population of Taiwan.

Chemosphere 2010 Sep 24;81(4):469-77. Epub 2010 Aug 24.

Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan 704, Taiwan.

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September 2010

A label-free differential proteomic analysis of mouse bronchoalveolar lavage fluid exposed to ultrafine carbon black.

Anal Chim Acta 2010 Jul 4;673(2):160-6. Epub 2010 Jun 4.

Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

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July 2010

Eliminating the limiting-current phenomenon by geometric field focusing into nanopores and nanoslots.

Phys Rev E Stat Nonlin Soft Matter Phys 2010 Apr 5;81(4 Pt 2):046301. Epub 2010 Apr 5.

Department of Chemical and Biomolecular Engineering, Center for Microfluidics and Medical Diagnostics, University of Notre Dame, Notre Dame, Indiana 46556, USA.

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April 2010

Characterization of centrosomal proteins Cep55 and pericentrin in intercellular bridges of mouse testes.

J Cell Biochem 2010 Apr;109(6):1274-85

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan, ROC.

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April 2010

Rectification, gating voltage, and interchannel communication of nanoslot arrays due to asymmetric entrance space charge polarization.

Phys Rev Lett 2009 Oct 8;103(15):154502. Epub 2009 Oct 8.

Department of Chemical and Biomolecular Engineering, Center for Microfluidics and Medical Diagnostics, University of Notre Dame, Notre Dame, Indiana 46556, USA.

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October 2009

A statistical procedure to selectively detect metabolite signals in LC-MS data based on using variable isotope ratios.

J Am Soc Mass Spectrom 2010 Feb 12;21(2):232-41. Epub 2009 Oct 12.

Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

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February 2010

Cell secretome analysis using hollow fiber culture system leads to the discovery of CLIC1 protein as a novel plasma marker for nasopharyngeal carcinoma.

J Proteome Res 2009 Dec;8(12):5465-74

Institute of Biopharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

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December 2009

Nonlinear current-voltage characteristics of nanochannels.

Phys Rev E Stat Nonlin Soft Matter Phys 2009 Apr 3;79(4 Pt 2):046305. Epub 2009 Apr 3.

Department of Chemical and Biomolecular Engineering, Center for Microfluidics and Medical Diagnostics, University of Notre Dame, Notre Dame, Indiana 46556, USA.

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April 2009

Vascularized groin lymph node transfer using the wrist as a recipient site for management of postmastectomy upper extremity lymphedema.

Plast Reconstr Surg 2009 Apr;123(4):1265-1275

Taoyuan, Taiwan From the Departments of Plastic and Reconstructive Surgery, General Surgery, and Nuclear Medicine, Chang Gung Memorial Hospital, Chang Gung Medical College, Chang Gung University, and the Department of Plastic and Reconstructive Surgery, E-Da Hospital.

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April 2009

The role of radioactive iodine therapy in young patients with papillary thyroid cancer.

Clin Nucl Med 2009 Jan;34(1):4-6

Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taiwan, Republic of China.

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January 2009

Proteomics analysis of nasopharyngeal carcinoma cell secretome using a hollow fiber culture system and mass spectrometry.

J Proteome Res 2009 Jan;8(1):380-9

Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

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January 2009

Strategy for determination of in vitro protein acetylation sites by using isotope-labeled acetyl coenzyme A and liquid chromatography-mass spectrometry.

Anal Chem 2008 Aug 11;80(16):6178-89. Epub 2008 Jul 11.

Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

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August 2008

Evaluation of electrospray ionization and atmospheric pressure chemical ionization for simultaneous detection of estrone and its metabolites using high-performance liquid chromatography/tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2007 Dec 22;860(1):49-56. Epub 2007 Oct 22.

Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan 70428, Taiwan.

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December 2007

Concurrent papillary thyroid cancer with pituitary ACTH-secreting tumor.

J Formos Med Assoc 2007 Apr;106(4):330-5

Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.

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April 2007

Body burdens of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls and their relations to estrogen metabolism in pregnant women.

Environ Health Perspect 2006 May;114(5):740-5

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Miaoli, and Graduate Institute of Occupational and Industrial Health, Kaohsiung Medical University, Kaohsiung, Taiwan.

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May 2006

Advantages and pitfalls of 18F-fluoro-2-deoxy-D-glucose positron emission tomography in detecting locally residual or recurrent nasopharyngeal carcinoma: comparison with magnetic resonance imaging.

Eur J Nucl Med Mol Imaging 2006 Sep 19;33(9):1032-40. Epub 2006 Apr 19.

Department of Nuclear Medicine, Chang Gung Memorial Hospital Linkou Medical Center, 5 Fu-Shin St, Kueishan, Taoyuan, Taiwan, 333, Republic of China.

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September 2006

Ovarian metastasis in a nulliparous woman with endometrial adenocarcinoma failing conservative hormonal treatment.

Gynecol Oncol 2005 May;97(2):652-5

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital Linkou Medical Center and Chang Gung University, 5 Fu-Shin St., Kueishan, Taoyuan 333, Taiwan.

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May 2005

The value of 18F-FDG PET in the detection of stage M0 carcinoma of the nasopharynx.

J Nucl Med 2005 Mar;46(3):405-10

Department of Nuclear Medicine, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.

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March 2005

Another designer steroid: discovery, synthesis, and detection of 'madol' in urine.

Rapid Commun Mass Spectrom 2005 ;19(6):781-4

UCLA Olympic Analytical Laboratory, Department of Molecular and Medical Pharmacology, University of California at Los Angeles, 2122 Granville Ave., Los Angeles, CA 90025, USA.

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May 2005

Does diabetes mellitus influence the efficacy of FDG-PET in the diagnosis of cervical cancer?

Eur J Nucl Med Mol Imaging 2005 Jun 10;32(6):647-52. Epub 2005 Feb 10.

Department of Nuclear Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.

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June 2005

Are dual-phase 18F-FDG PET scans necessary in nasopharyngeal carcinoma to assess the primary tumour and loco-regional nodes?

Eur J Nucl Med Mol Imaging 2005 May 30;32(5):541-8. Epub 2004 Dec 30.

Department of Nuclear Medicine, Chang Gung Memorial University Hospital, Linkou Medical Center, Taiwan.

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May 2005

Papillary thyroid cancer with chest metastases only detected using radioactive iodine.

Chang Gung Med J 2004 Sep;27(9):663-72

Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Fushing Street, Gueishan Shiang, Taoyuan, Taiwan 333, ROC.

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September 2004

[Strategies to improve protection from glutaraldehyde in endoscopic examination].

Hu Li Za Zhi 2004 Aug;51(4):53-9

Department of Health Examiniation, Chang Gung Memorial Hospital at Kaohsiung, ROC.

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August 2004

Tetrahydrogestrinone: discovery, synthesis, and detection in urine.

Rapid Commun Mass Spectrom 2004 ;18(12):1245-049

UCLA Olympic Analytical Laboratory, Department of Molecular and Medical Pharmacology, University of California at Los Angeles, 2122 Granville Avenue, Los Angeles, CA 90025, USA.

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July 2004

Nodal metastases of nasopharyngeal carcinoma: patterns of disease on MRI and FDG PET.

Eur J Nucl Med Mol Imaging 2004 Aug 9;31(8):1073-80. Epub 2004 Mar 9.

Department of Diagnostic Radiology, Chang Gung Memorial Hospital Linkou Medical Center, Taiwan.

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August 2004

Antioxidant activity of 3-dehydroshikimic acid in liposomes, emulsions, and bulk oil.

J Agric Food Chem 2003 Apr;51(9):2753-7

Department of Food Science & Human Nutrition, Michigan State University, East Lansing, MI 48824-1224, USA.

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April 2003

Pore structure effects on Ca-based sorbent sulfation capacity at medium temperatures: activated carbon as sorbent/catalyst support.

J Air Waste Manag Assoc 2002 Nov;52(11):1281-7

Department of Environmental Engineering, National Chung-Hsing University, Taiwan, Republic of China.

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November 2002