Yu Nie

Yu Nie

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Bioactive iron oxide nanoparticles suppress osteoclastogenesis and ovariectomy-induced bone loss through regulating the TRAF6-p62-CYLD signaling complex.

Acta Biomater 2020 Feb 20;103:281-292. Epub 2019 Dec 20.

National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China; Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2019.12.022DOI Listing
February 2020

Integration of Indocyanine Green Analogs as Near-Infrared Fluorescent Carrier for Precise Imaging-Guided Gene Delivery.

Small 2020 Feb 5:e1906538. Epub 2020 Feb 5.

National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, P. R. China.

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http://dx.doi.org/10.1002/smll.201906538DOI Listing
February 2020

Transplantation of murine neonatal cardiac macrophage improves adult cardiac repair.

Cell Mol Immunol 2020 Feb 13. Epub 2020 Feb 13.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.

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http://dx.doi.org/10.1038/s41423-020-0371-5DOI Listing
February 2020

Arterial Sca1 Vascular Stem Cells Generate De Novo Smooth Muscle for Artery Repair and Regeneration.

Cell Stem Cell 2020 Jan 27;26(1):81-96.e4. Epub 2019 Dec 27.

The State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China; Key Laboratory of Regenerative Medicine of the Ministry of Education, Jinan University, Guangzhou 510632, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2019.11.010DOI Listing
January 2020

A genetic system for tissue-specific inhibition of cell proliferation.

Development 2020 Jan 27. Epub 2020 Jan 27.

The State Key Laboratory of Cell Biology, CAS Center for Excellence on Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China

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http://dx.doi.org/10.1242/dev.183830DOI Listing
January 2020

Individualized treatment of pediatric inguinal hernia reduces adolescent recurrence rate: an analysis of 3006 cases.

Surg Today 2019 Dec 19. Epub 2019 Dec 19.

Department of Hernia and Abdominal Wall Surgery, Beijing Chaoyang Hospital, Capital Medical University, 5 Jingyuan Road, Shijingshan District, Beijing, 100043, China.

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http://dx.doi.org/10.1007/s00595-019-01940-4DOI Listing
December 2019

Recent advances in myocardial regeneration strategy.

J Int Med Res 2019 Nov 23;47(11):5453-5464. Epub 2019 Oct 23.

Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China.

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http://dx.doi.org/10.1177/0300060519862663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862912PMC
November 2019

Overcoming the Reticuloendothelial System Barrier to Drug Delivery with a "Don't-Eat-Us" Strategy.

ACS Nano 2019 Nov 7;13(11):13015-13026. Epub 2019 Nov 7.

Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Pharmaceutical Sciences , Southwest University , Chongqing 400715 , P.R. China.

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http://dx.doi.org/10.1021/acsnano.9b05679DOI Listing
November 2019

Non-Cardiomyocytes in Heart Regeneration.

Curr Drug Targets 2018 ;19(9):1077-1086

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.

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http://dx.doi.org/10.2174/1389450119666180518111931DOI Listing
October 2019

Effects of bronchial blockers on one-lung ventilation in general anesthesia: A randomized controlled trail.

Medicine (Baltimore) 2019 Oct;98(41):e17387

Department of Anesthesiology, Cangzhou Central Hospital, Cangzhou, Hebei Province, China.

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http://dx.doi.org/10.1097/MD.0000000000017387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799619PMC
October 2019

The future of organ-oriented research and treatment.

Hepatobiliary Surg Nutr 2019 Oct;8(5):502-505

Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.

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http://dx.doi.org/10.21037/hbsn.2019.08.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791979PMC
October 2019

Relief of irritable bowel syndrome by fecal microbiota transplantation is associated with changes in diversity and composition of the gut microbiota.

J Dig Dis 2019 Aug 7;20(8):401-408. Epub 2019 Jul 7.

Department of Gastroenterology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China.

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http://dx.doi.org/10.1111/1751-2980.12756DOI Listing
August 2019

Virus-inspired and mimetic designs in non-viral gene delivery.

J Gene Med 2019 Jul 13;21(7):e3090. Epub 2019 Jun 13.

National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jgm.3090
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http://dx.doi.org/10.1002/jgm.3090DOI Listing
July 2019

Exosome-derived galectin-9 may be a novel predictor of rejection and prognosis after liver transplantation.

J Zhejiang Univ Sci B 2019 Jul;20(7):605-612

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.

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http://dx.doi.org/10.1631/jzus.B1900051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586996PMC
July 2019

Reassessment of c-Kit Cells for Cardiomyocyte Contribution in Adult Heart.

Circulation 2019 Jul 8;140(2):164-166. Epub 2019 Jul 8.

State Key Laboratory of Cell Biology, Chinese Academy of Sciences Center for Excellence on Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, China (L.H., M.H., Z.Z., Y.L., X.H., X.L., W.P., H.Z., B.Z.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.039909DOI Listing
July 2019

PDGFR-β Signaling Regulates Cardiomyocyte Proliferation and Myocardial Regeneration.

Cell Rep 2019 Jul;28(4):966-978.e4

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193084
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http://dx.doi.org/10.1016/j.celrep.2019.06.065DOI Listing
July 2019

Synthetic nucleic acid nanomedicines: A Chinese perspective.

J Gene Med 2019 Jul;21(7):e3111

National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China.

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http://dx.doi.org/10.1002/jgm.3111DOI Listing
July 2019

Intronic Polymorphisms in Gene of Second Heart Field as Risk Factors for Human Congenital Heart Disease in a Chinese Population.

DNA Cell Biol 2019 Jun 23;38(6):521-531. Epub 2019 Apr 23.

1 Center for Cardiac Surgery, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1089/dna.2018.4254DOI Listing
June 2019

Proteomic profiling of key transcription factors in the process of neonatal mouse cardiac regeneration capacity loss.

Cell Biol Int 2019 Jun 12. Epub 2019 Jun 12.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167A Beilishi Road, Xi Cheng District, Beijing, 100037, P.R. China.

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http://dx.doi.org/10.1002/cbin.11192DOI Listing
June 2019

Minor alleles of genetic variants in second heart field increase the risk of hypoplastic right heart syndrome.

J Genet 2019 06;98(2)

Department of Cardiac Surgery, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100037, People's Republic of China.

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June 2019

Iron oxide nanoparticles promote macrophage autophagy and inflammatory response through activation of toll-like Receptor-4 signaling.

Biomaterials 2019 05 28;203:23-30. Epub 2019 Feb 28.

National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China; Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2019.02.026DOI Listing
May 2019

Proanthocyanidins of Natural Origin: Molecular Mechanisms and Implications for Lipid Disorder and Aging-Associated Diseases.

Adv Nutr 2019 05;10(3):464-478

Department of Analytical, Environmental & Forensic Sciences, School of Population Health & Environmental Sciences, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1093/advances/nmy118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520035PMC
May 2019

Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction.

Nat Genet 2019 04 18;51(4):728-738. Epub 2019 Feb 18.

The State Key Laboratory of Cell Biology, CAS Center for Excellence on Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.

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http://www.nature.com/articles/s41588-019-0346-6
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http://dx.doi.org/10.1038/s41588-019-0346-6DOI Listing
April 2019

Author Correction: Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction.

Nat Genet 2019 04;51(4):766

The State Key Laboratory of Cell Biology, CAS Center for Excellence on Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.

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http://dx.doi.org/10.1038/s41588-019-0388-9DOI Listing
April 2019

Molecular characterization, pathogenicity, and protection efficacy analysis of 2 wild-type lentogenic class I Newcastle disease viruses from chickens in China.

Poult Sci 2019 Feb;98(2):602-612

Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou 510642, P. R. China.

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https://academic.oup.com/ps/advance-article/doi/10.3382/ps/p
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http://dx.doi.org/10.3382/ps/pey471DOI Listing
February 2019

A long noncoding RNA NR_045363 controls cardiomyocyte proliferation and cardiac repair.

J Mol Cell Cardiol 2019 02 13;127:105-114. Epub 2018 Dec 13.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2018.12.005DOI Listing
February 2019

The Effects of Diabetic Duration on Lacrimal Functional Unit in Patients with Type II Diabetes.

J Ophthalmol 2019 10;2019:8127515. Epub 2019 Jan 10.

Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin 300384, China.

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http://dx.doi.org/10.1155/2019/8127515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350560PMC
January 2019

Fate Mapping of Sca1 Cardiac Progenitor Cells in the Adult Mouse Heart.

Circulation 2018 12;138(25):2967-2969

State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences (J.T., Y.L., X.H., L.H., L.Z., H.W., W.Y., W.P., B.Z.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036210DOI Listing
December 2018

Machine perfusion for liver transplantation: A concise review of clinical trials.

Hepatobiliary Pancreat Dis Int 2018 Oct 26;17(5):387-391. Epub 2018 Jun 26.

Division of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China; Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Hangzhou 310003, China; Collaborative Innovation Centers for Diagnosis Treatment of Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. Electronic address:

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http://dx.doi.org/10.1016/j.hbpd.2018.06.003DOI Listing
October 2018

Novel Delivery of Mitoxantrone with Hydrophobically Modified Pullulan Nanoparticles to Inhibit Bladder Cancer Cell and the Effect of Nano-drug Size on Inhibition Efficiency.

Nanoscale Res Lett 2018 Oct 30;13(1):345. Epub 2018 Oct 30.

Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province and Department of Pharmacy, School of Medicine, Hunan Normal University, Changsha, 410013, China.

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https://nanoscalereslett.springeropen.com/articles/10.1186/s
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http://dx.doi.org/10.1186/s11671-018-2769-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207605PMC
October 2018

Histopathologic features of alcoholic cardiomyopathy compared with idiopathic dilated cardiomyopathy.

Medicine (Baltimore) 2018 Sep;97(39):e12259

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1097/MD.0000000000012259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181549PMC
September 2018

The role of FTO variants in the susceptibility of polycystic ovary syndrome and in vitro fertilization outcomes in Chinese women.

Gynecol Endocrinol 2018 Aug 20;34(8):719-723. Epub 2018 Feb 20.

a Institute of Biology, School of Pharmaceutical and Biological Science , University of South China , Hengyang , PR China.

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https://www.tandfonline.com/doi/full/10.1080/09513590.2018.1
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http://dx.doi.org/10.1080/09513590.2018.1441397DOI Listing
August 2018

Impact of local administration of various doses of dexmedetomidine on ropivacaine-induced lumbar plexus-sciatic nerve block.

Exp Ther Med 2018 Aug 24;16(2):711-717. Epub 2018 May 24.

Department of Anesthesiology, Central Hospital of Cangzhou, Cangzhou, Hebei 061000, P.R. China.

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http://dx.doi.org/10.3892/etm.2018.6218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090230PMC
August 2018

Fatty liver mediated by peroxisome proliferator-activated receptor-α DNA methylation can be reversed by a methylation inhibitor and curcumin.

J Dig Dis 2018 Jul 15;19(7):421-430. Epub 2018 Jul 15.

Department of Gastroenterology and Hepatology, Guangzhou Digestive Diseases Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China.

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http://dx.doi.org/10.1111/1751-2980.12610DOI Listing
July 2018

Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease.

BMC Genomics 2018 Jun 4;19(1):428. Epub 2018 Jun 4.

Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Peking University, Beijing, 100871, China.

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http://dx.doi.org/10.1186/s12864-018-4814-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987557PMC
June 2018

Enhancing the precision of genetic lineage tracing using dual recombinases.

Nat Med 2017 Dec 13;23(12):1488-1498. Epub 2017 Nov 13.

State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), University of Chinese Academy of Sciences, Shanghai, China.

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http://dx.doi.org/10.1038/nm.4437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913096PMC
December 2017

Proanthocyanidin trimer gallate modulates lipid deposition and fatty acid desaturation in .

FASEB J 2017 11 31;31(11):4891-4902. Epub 2017 Jul 31.

Analytical and Environmental Sciences Division, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom;

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http://dx.doi.org/10.1096/fj.201700438RDOI Listing
November 2017

Association of Mental Health Status With Perception of Nasal Function.

JAMA Facial Plast Surg 2017 Sep;19(5):369-377

Rhinology and Skull Base Surgery, St Vincent's Centre for Applied Medical Research, University of New South Wales, Darlinghurst, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1001/jamafacial.2017.0459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710631PMC
September 2017

Iridium-Catalyzed Asymmetric Hydrogenation of 2H-Chromenes: A Highly Enantioselective Approach to Isoflavan Derivatives.

Org Lett 2017 09 31;19(18):4884-4887. Epub 2017 Aug 31.

School of Pharmacy and ‡School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, P. R. China.

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http://dx.doi.org/10.1021/acs.orglett.7b02341DOI Listing
September 2017

Preexisting endothelial cells mediate cardiac neovascularization after injury.

J Clin Invest 2017 Aug 26;127(8):2968-2981. Epub 2017 Jun 26.

The State Key Laboratory of Cell Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology.

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http://dx.doi.org/10.1172/JCI93868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531398PMC
August 2017

Identification of a hybrid myocardial zone in the mammalian heart after birth.

Nat Commun 2017 07 20;8(1):87. Epub 2017 Jul 20.

The State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.

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http://dx.doi.org/10.1038/s41467-017-00118-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519540PMC
July 2017

[Risk factors of perioperative intra-aortic balloon pump complications in cardiac surgery: a 12-year single-institution analysis].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2017 Jun;29(6):506-510

Department of Cardiac Surgery ICU, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovascular Diseases, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, Beijing 100037, China (Zhou HY, Zhang YH, Du Y, Cao FF, Wang J, Zhao L, Zhang HT); Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovascular Diseases, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, Beijing 100037, China (Nie Y). Corresponding author: Zhang Haitao, Email:

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http://dx.doi.org/10.3760/cma.j.issn.2095-4352.2017.06.006DOI Listing
June 2017

Development of a bacterial-based negative selection system for rapid screening of active single guide RNAs.

Biotechnol Lett 2017 Mar 17;39(3):351-358. Epub 2016 Nov 17.

Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510006, People's Republic of China.

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http://dx.doi.org/10.1007/s10529-016-2259-0DOI Listing
March 2017

Synthesis of Pt/KCO/MgAlO-reduced graphene oxide hybrids as promising NO storage-reduction catalysts with superior catalytic performance.

Sci Rep 2017 02 16;7:42862. Epub 2017 Feb 16.

College of Environmental Science and Engineering, Beijing Forestry University, 35 Qinghua East Road, Haidian District, Beijing 100083, P. R. China.

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http://dx.doi.org/10.1038/srep42862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311869PMC
February 2017

The role of ADIPOQ methylation in curcumin-administrated experimental nonalcoholic fatty liver disease.

J Dig Dis 2016 Dec;17(12):829-836

Department of Gastroenterology and Hepatology, Guangzhou Institute of Digestive Disease, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China.

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http://doi.wiley.com/10.1111/1751-2980.12431
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http://dx.doi.org/10.1111/1751-2980.12431DOI Listing
December 2016

Effects of Liposomes Charge on Extending Sciatic Nerve Blockade of N-ethyl Bromide of Lidocaine in Rats.

Sci Rep 2016 12 7;6:38582. Epub 2016 Dec 7.

National Engineering Research Centre for Biomaterials, Sichuan University, Chengdu 610064, Sichuan, P.R. China.

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http://dx.doi.org/10.1038/srep38582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141481PMC
December 2016

Multi-Responsive "Turn-On" Nanocarriers for Efficient Site-Specific Gene Delivery In Vitro and In Vivo.

Adv Healthc Mater 2016 11 26;5(21):2799-2812. Epub 2016 Sep 26.

National Engineering Research Center for Biomaterials, Sichuan University, 29 Wangjiang Road, Chengdu, 610064, P. R. China.

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http://dx.doi.org/10.1002/adhm.201600710DOI Listing
November 2016

Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration.

Nat Commun 2016 11 18;7:13369. Epub 2016 Nov 18.

Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.

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http://dx.doi.org/10.1038/ncomms13369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120209PMC
November 2016

Liposomes as a Novel Ocular Delivery System for Brinzolamide: In Vitro and In Vivo Studies.

AAPS PharmSciTech 2016 Jun 3;17(3):710-7. Epub 2015 Sep 3.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan, 610041, China.

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http://dx.doi.org/10.1208/s12249-015-0382-1DOI Listing
June 2016

Specially-Made Lipid-Based Assemblies for Improving Transmembrane Gene Delivery: Comparison of Basic Amino Acid Residue Rich Periphery.

Mol Pharm 2016 06 12;13(6):1809-21. Epub 2016 May 12.

National Engineering Research Center for Biomaterials, Sichuan University , Chengdu 610064, Sichuan, P. R. China.

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http://dx.doi.org/10.1021/acs.molpharmaceut.5b00967DOI Listing
June 2016

The Human Myotrophin Variant Attenuates MicroRNA-Let-7 Binding Ability but Not Risk of Left Ventricular Hypertrophy in Human Essential Hypertension.

PLoS One 2015 14;10(8):e0135526. Epub 2015 Aug 14.

Sino-German Laboratory for Molecular Medicine, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135526PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537090PMC
May 2016

GATA4 regulates Fgf16 to promote heart repair after injury.

Development 2016 Mar 18;143(6):936-49. Epub 2016 Feb 18.

Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210 China

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http://dx.doi.org/10.1242/dev.130971DOI Listing
March 2016

Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes.

Cell Res 2016 Jan 4;26(1):119-30. Epub 2015 Dec 4.

Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Graduate School of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

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http://dx.doi.org/10.1038/cr.2015.143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816131PMC
January 2016

Endocardium Contributes to Cardiac Fat.

Circ Res 2016 Jan 9;118(2):254-65. Epub 2015 Dec 9.

From the Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China (H.Z., W.P., Q.L., L.H., X.H., X.T., L.Z., B.Z.); Department of Cardiovascular Surgery, Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China (Y.N., S.H.); Department of Chemical Pathology, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China (K.O.L.); Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai China (B.Z.); and ShanghaiTech University, Shanghai, China (B.Z.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.307202DOI Listing
January 2016

Association of adiponectin gene variation with progression of nonalcoholic fatty liver disease: A 4-year follow-up survey.

J Dig Dis 2015 Oct;16(10):601-9

Department of Gastroenterology and Hepatology, Guangzhou Digestive Diseases Center, Guangzhou First People's Hospital, Guangzhou Medical University, Guangdong, China.

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http://doi.wiley.com/10.1111/1751-2980.12288
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October 2015

Acute inflammation stimulates a regenerative response in the neonatal mouse heart.

Cell Res 2015 Oct 11;25(10):1137-51. Epub 2015 Sep 11.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.

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http://dx.doi.org/10.1038/cr.2015.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650627PMC
October 2015

Effect of telmisartan on the therapeutic efficacy of pitavastatin in high-fat diet induced dyslipidemic guinea pigs.

Eur J Pharmacol 2015 Sep 6;762:364-71. Epub 2015 Jun 6.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu 610041, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2015.06.005DOI Listing
September 2015

Insight into the efficient transfection activity of a designed low aggregated magnetic polyethyleneimine/DNA complex in serum-containing medium and the application in vivo.

Biomater Sci 2015 Mar 5;3(3):446-56. Epub 2014 Nov 5.

National Engineering Research Center for Biomaterials and Sichuan University, Chengdu 610064, P. R. China.

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http://dx.doi.org/10.1039/c4bm00317aDOI Listing
March 2015

Dual-targeted polyplexes based on sequence-defined peptide-PEG-oligoamino amides.

J Pharm Sci 2015 Feb 29;104(2):464-75. Epub 2014 Sep 29.

Pharmaceutical Biotechnology, Center for System-Based Drug Research, Ludwig-Maximilians-University Munich, Munich, D-81377, Germany.

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http://dx.doi.org/10.1002/jps.24194DOI Listing
February 2015

Extending the time window of mammalian heart regeneration by thymosin beta 4.

J Cell Mol Med 2014 Dec 6;18(12):2417-24. Epub 2014 Oct 6.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1111/jcmm.12421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302647PMC
December 2014

Ectopic expression of reprogramming factors enhances the development of cloned porcine embryos.

Biotechnol Lett 2014 Oct 15;36(10):1953-61. Epub 2014 Jun 15.

State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Higher Education Mega Center, Guangzhou, 510006, People's Republic of China.

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http://dx.doi.org/10.1007/s10529-014-1580-8DOI Listing
October 2014

Generation of CD44 gene-deficient mouse derived induced pluripotent stem cells: CD44 gene-deficient iPSCs.

In Vitro Cell Dev Biol Anim 2014 Oct 21;50(9):874-82. Epub 2014 Jun 21.

State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Higher Education Mega Center, Guangzhou, 510006, People's Republic of China,

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http://link.springer.com/10.1007/s11626-014-9786-6
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October 2014

Damage of zona pellucida reduces the developmental potential and quality of porcine circovirus type 2-infected oocytes after parthenogenetic activation.

Theriogenology 2014 Oct 24;82(6):790-9. Epub 2014 Jun 24.

State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.theriogenology.2014.06.003DOI Listing
October 2014

Cardiomyocyte cytokinesis score: a potential method for cardiomyocyte proliferation.

Cell Biol Int 2014 Sep 16;38(9):1032-40. Epub 2014 Jun 16.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, People's Republic of China.

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http://dx.doi.org/10.1002/cbin.10307DOI Listing
September 2014

Exogenous expression of OCT4 facilitates oocyte-mediated reprogramming in cloned porcine embryos.

Mol Reprod Dev 2014 Sep 18;81(9):820-32. Epub 2014 Aug 18.

State Key Laboratory of Biocontrol, Sun Yat-Sen University, Guangzhou, P. R. China.

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http://dx.doi.org/10.1002/mrd.22351DOI Listing
September 2014

The association between androgen receptor gene CAG polymorphism and polycystic ovary syndrome: a case-control study and meta-analysis.

J Assist Reprod Genet 2014 Sep 2;31(9):1211-9. Epub 2014 Jul 2.

Department of Pharmacy and Biological Sciences, University of South China, Heng yang, 421001, Hunan Province, People's Republic of China,

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http://dx.doi.org/10.1007/s10815-014-0286-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156942PMC
September 2014

A Polymorphism in Hepatocyte Nuclear Factor 1 Alpha, rs7310409, Is Associated with Left Main Coronary Artery Disease.

Biochem Res Int 2014 18;2014:924105. Epub 2014 Aug 18.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishilu Street, Beijing 100037, China.

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http://dx.doi.org/10.1155/2014/924105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151485PMC
September 2014

Multi-investigator letter on reproducibility of neonatal heart regeneration following apical resection.

Stem Cell Reports 2014 Jul 8;3(1). Epub 2014 Jul 8.

Brigham Regenerative Medicine Center, Brigham and Women's Hospital Cardiovascular Division, Brigham and Women's Hospital Partners Research Facility, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.stemcr.2014.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110774PMC
July 2014

[Automatic analysis pipeline of next-generation sequencing data].

Yi Chuan 2014 Jun;36(6):618-24

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.

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http://dx.doi.org/10.3724/SP.J.1005.2014.0618DOI Listing
June 2014

Polymorphisms of VEGF, TGFβ1, TGFβR2 and conotruncal heart defects in a Chinese population.

Mol Biol Rep 2014 Mar 18;41(3):1763-70. Epub 2014 Jan 18.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital & Cardiovascular Institute, Chinese Academy of Medical Science, Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1007/s11033-014-3025-9DOI Listing
March 2014

p53 mediated apoptosis by reduction sensitive shielding ternary complexes based on disulfide linked PEI ternary complexes.

Biomaterials 2014 Feb 20;35(5):1657-66. Epub 2013 Nov 20.

National Engineering Research Center for Biomaterials, Sichuan University, No. 29, Wangjiang Road, Chengdu 610064, Sichuan, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2013.10.073DOI Listing
February 2014

Cholesterol derivatives based charged liposomes for doxorubicin delivery: preparation, in vitro and in vivo characterization.

Theranostics 2012 13;2(11):1092-103. Epub 2012 Nov 13.

National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, Sichuan, PR China.

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http://dx.doi.org/10.7150/thno.4949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516839PMC
January 2014

The efficacy, safety and cost-effectiveness of hydrotalcite versus esomeprazole in on-demand therapy of NERD: A multicenter, randomized, open-label study in China.

J Dig Dis 2013 Sep;14(9):463-8

Department of Gastroenterology and Hepatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong Province, China.

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http://dx.doi.org/10.1111/1751-2980.12069DOI Listing
September 2013

Reciprocal regulation of miR-23a and lysophosphatidic acid receptor signaling in cardiomyocyte hypertrophy.

Biochim Biophys Acta 2013 Aug 25;1831(8):1386-94. Epub 2013 May 25.

Fuwai Hospital, National Centre for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.

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http://dx.doi.org/10.1016/j.bbalip.2013.05.005DOI Listing
August 2013

Circulating miRNAs reflect early myocardial injury and recovery after heart transplantation.

J Cardiothorac Surg 2013 Jul 1;8:165. Epub 2013 Jul 1.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, People's Republic of China.

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http://dx.doi.org/10.1186/1749-8090-8-165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716980PMC
July 2013

Association between metabolic syndrome and the development of non-alcoholic fatty liver disease.

Exp Ther Med 2013 Jul 29;6(1):77-84. Epub 2013 Apr 29.

Departments of Infectious Disease, Guangzhou Medical University, Guangzhou, Guangdong 510180;

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http://dx.doi.org/10.3892/etm.2013.1090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735568PMC
July 2013

MicroRNA profiling during rat ventricular maturation: A role for miR-29a in regulating cardiomyocyte cell cycle re-entry.

FEBS Lett 2013 May 12;587(10):1548-55. Epub 2013 Apr 12.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100037, China.

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http://dx.doi.org/10.1016/j.febslet.2013.01.075DOI Listing
May 2013

Development of a reduction-sensitive diselenide-conjugated oligoethylenimine nanoparticulate system as a gene carrier.

Int J Nanomedicine 2012 31;7:3991-4006. Epub 2012 Jul 31.

National Engineering Research Center for Biomaterials, West China School of Pharmacy, Sichuan University, 29 Wangjiang Road, Chengdu, Sichuan, People's Republic of China.

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http://dx.doi.org/10.2147/IJN.S32961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418076PMC
March 2013

Polyethyleneimine/DNA polyplexes with reduction-sensitive hyaluronic acid derivatives shielding for targeted gene delivery.

Biomaterials 2013 Jan 3;34(4):1235-45. Epub 2012 Nov 3.

National Engineering Research Center for Biomaterials, Sichuan University, No. 29, Wangjiang Road, Chengdu, Sichuan 610064, PR China.

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http://dx.doi.org/10.1016/j.biomaterials.2012.09.049DOI Listing
January 2013

MicroRNA-24 regulates cardiac fibrosis after myocardial infarction.

J Cell Mol Med 2012 Sep;16(9):2150-60

State Key Laboratory of Translational Cardiovascular Medicine, Fuwai Hospital & Cardiovascular Institute, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1111/j.1582-4934.2012.01523.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822985PMC
September 2012

MicroRNA-193 pro-proliferation effects for bone mesenchymal stem cells after low-level laser irradiation treatment through inhibitor of growth family, member 5.

Stem Cells Dev 2012 Sep 20;21(13):2508-19. Epub 2012 Apr 20.

State Key Laboratory of Cardiovascular Medicine, Fuwai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1089/scd.2011.0695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424971PMC
September 2012

Developmental changes in lysophospholipid receptor expression in rodent heart from near-term fetus to adult.

Mol Biol Rep 2012 Sep 28;39(9):9075-84. Epub 2012 Jun 28.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital & Cardiovascular Institute, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100037, China.

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http://dx.doi.org/10.1007/s11033-012-1778-6DOI Listing
September 2012

Investigation of PEG-PLGA-PEG nanoparticles-based multipolyplexes for IL-18 gene delivery.

J Biomater Appl 2012 May 27;26(8):893-916. Epub 2011 Jan 27.

National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, Sichuan, China.

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http://dx.doi.org/10.1177/0885328210384889DOI Listing
May 2012

Natural course of nonalcoholic fatty liver disease in southern China: a prospective cohort study.

J Dig Dis 2012 Mar;13(3):153-60

Department of Gastroenterology and Hepatology, Guangzhou First Municipal People's Hospital, Guangzhou Medical College, Guangzhou, Guangdong Province, China.

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http://dx.doi.org/10.1111/j.1751-2980.2011.00571.xDOI Listing
March 2012

Methylenetetrahydrofolate reductase C677T and reduced folate carrier 80 G>A polymorphisms are associated with an increased risk of conotruncal heart defects.

Clin Chem Lab Med 2012 Feb 4;50(8):1455-61. Epub 2012 Feb 4.

State Key Laboratory of Cardiovascular Disease, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beijing, PR China.

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http://dx.doi.org/10.1515/cclm-2011-0759DOI Listing
February 2012

A new carbamate with cytotoxic activity from the aerial parts of Siegesbeckia pubecens.

Chin J Nat Med 2012 Jan;10(1):13-5

Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.

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http://dx.doi.org/10.1016/S1875-5364(12)60002-8DOI Listing
January 2012

Methylenetetrahydrofolate reductase C677T polymorphism and congenital heart disease: a meta-analysis.

Clin Chem Lab Med 2011 Dec 28;49(12):2101-8. Epub 2011 Jul 28.

State Key Laboratory of Translational Cardiovascular Medicine, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China.

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http://dx.doi.org/10.1515/CCLM.2011.673DOI Listing
December 2011

Identification of MicroRNAs involved in hypoxia- and serum deprivation-induced apoptosis in mesenchymal stem cells.

Int J Biol Sci 2011 9;7(6):762-8. Epub 2011 Jun 9.

Research Center for Cardiovascular Regenerative Medicine, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119848PMC
http://dx.doi.org/10.7150/ijbs.7.762DOI Listing
November 2011

Characterization of 9-nitrocamptothecin liposomes: anticancer properties and mechanisms on hepatocellular carcinoma in vitro and in vivo.

PLoS One 2011 9;6(6):e21064. Epub 2011 Jun 9.

Department of General Surgery, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021064PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111480PMC
October 2011

Epidermal growth factor-PEG functionalized PAMAM-pentaethylenehexamine dendron for targeted gene delivery produced by click chemistry.

Biomacromolecules 2011 Jun 27;12(6):2039-47. Epub 2011 Apr 27.

Department of Pharmacy, and Center for Nanoscience (CeNS), Ludwig-Maximilians Universität , Butenandtstrasse 5-13, D-81377 Munich, Germany.

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http://pubs.acs.org/doi/abs/10.1021/bm101464n
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June 2011

Dual-targeted polyplexes: one step towards a synthetic virus for cancer gene therapy.

J Control Release 2011 May 8;152(1):127-34. Epub 2011 Mar 8.

Pharmaceutical Biotechnology, Center for Drug Research, and Center for NanoScience (CeNS), Ludwig-Maximilians-University, Butenandstr. 5-13, D-81377 Munich, Germany.

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http://dx.doi.org/10.1016/j.jconrel.2011.02.028DOI Listing
May 2011

Gene transfer efficacies of serum-resistant amino acids-based cationic lipids: dependence on headgroup, lipoplex stability and cellular uptake.

Int J Pharm 2011 Apr 1;408(1-2):183-90. Epub 2011 Feb 1.

National Engineering Research Center for Biomaterials, Sichuan University, 29 Wangjiang Road, Chengdu 610064, Sichuan, China.

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http://dx.doi.org/10.1016/j.ijpharm.2011.01.051DOI Listing
April 2011

[Role of circulating microRNA on clinical diagnosis of cardiovascular diseases].

Zhonghua Xin Xue Guan Bing Za Zhi 2011 Apr;39(4):377-82

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http://dx.doi.org/10.3760/cma.j.issn.0253-3758.2011.04.022DOI Listing
April 2011