Yousang Hwang

Yousang Hwang

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Yousang Hwang

Yousang Hwang

Publications by authors named "Yousang Hwang"

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15Publications

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CREB promotes beta cell gene expression by targeting Its coactivators to tissue-specific enhancers.

Mol Cell Biol 2019 Jun 10. Epub 2019 Jun 10.

Peptide Biology Laboratories, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA

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http://dx.doi.org/10.1128/MCB.00200-19DOI Listing
June 2019

Combination Targeting of the Bromodomain and Acetyltransferase Active Site of p300/CBP.

Biochemistry 2019 Apr 11;58(16):2133-2143. Epub 2019 Apr 11.

Division of Genetics, Department of Medicine , Brigham and Women's Hospital , Boston , Massachusetts 02115 , United States.

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http://dx.doi.org/10.1021/acs.biochem.9b00160DOI Listing
April 2019

Hydrazide Mimics for Protein Lysine Acylation To Assess Nucleosome Dynamics and Deubiquitinase Action.

J Am Chem Soc 2018 Aug 24;140(30):9478-9485. Epub 2018 Jul 24.

Department of Pharmacology and Molecular Sciences , Johns Hopkins University School of Medicine , Baltimore , Maryland 21205 , United States.

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http://dx.doi.org/10.1021/jacs.8b03572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070418PMC
August 2018

Enzyme-catalyzed expressed protein ligation.

Nat Methods 2016 Nov 26;13(11):925-927. Epub 2016 Sep 26.

Department of Pharmacology and Molecular and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088058PMC
http://dx.doi.org/10.1038/nmeth.4004DOI Listing
November 2016

Mechanistic analysis of ghrelin-O-acyltransferase using substrate analogs.

Bioorg Chem 2015 Oct 13;62:64-73. Epub 2015 Jul 13.

Department of Pharmacology & Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2015.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567917PMC
October 2015

Inhibition of ghrelin O-acyltransferase attenuates food deprivation-induced increases in ingestive behavior.

Horm Behav 2013 Apr 8;63(4):667-73. Epub 2013 Feb 8.

Department of Biology, Georgia State University, Atlanta, GA 30302-4010, USA.

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http://dx.doi.org/10.1016/j.yhbeh.2013.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633643PMC
April 2013

Ghrelin O-acyltransferase assays and inhibition.

Methods Enzymol 2012 ;514:205-28

Department of Pharmacology & Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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https://linkinghub.elsevier.com/retrieve/pii/B97801238127280
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http://dx.doi.org/10.1016/B978-0-12-381272-8.00013-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763810PMC
February 2013

Electrophilic tuning of the chemoprotective natural product sulforaphane.

Proc Natl Acad Sci U S A 2010 May 3;107(21):9590-5. Epub 2010 May 3.

Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.1004104107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906893PMC
May 2010

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator.

Nature 2008 Feb;451(7180):846-50

Program in Gene Expression and Regulation, The Wistar Institute, 3601 Spruce Street, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/nature06546DOI Listing
February 2008

A selective chemical probe for coenzyme A-requiring enzymes.

Angew Chem Int Ed Engl 2007 ;46(40):7621-4

Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1002/anie.200702485DOI Listing
December 2007

Enzymatic and cellular study of a serotonin N-acetyltransferase phosphopantetheine-based prodrug.

Bioorg Med Chem 2007 Mar 13;15(5):2147-55. Epub 2006 Dec 13.

Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.bmc.2006.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1831523PMC
March 2007

Efficient synthesis of phosphorylated prodrugs with bis(POM)-phosphoryl chloride.

Org Lett 2004 May;6(10):1555-6

Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 725 N. Wolfe St. Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1021/ol049714vDOI Listing
May 2004