Young-hun Lee

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Young-hun Lee

Publications by authors named "Young-hun Lee"

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24Publications

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Processing of syndecan-2 by matrix metalloproteinase-14 and effect of its cleavage on VEGF-induced tube formation of HUVECs.

Biochem J 2017 11 1;474(22):3719-3732. Epub 2017 Nov 1.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea

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November 2017

PTK6 Localized at the Plasma Membrane Promotes Cell Proliferation and MigratiOn Through Phosphorylation of Eps8.

J Cell Biochem 2017 09 15;118(9):2887-2895. Epub 2017 May 15.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.

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September 2017

Syndecan-2 cytoplasmic domain up-regulates matrix metalloproteinase-7 expression via the protein kinase Cγ-mediated FAK/ERK signaling pathway in colon cancer.

J Biol Chem 2017 09 16;292(39):16321-16332. Epub 2017 Aug 16.

From the Department of Life Sciences, Research Center for Cellular Homeostasis, Ewha Womans University, Seoul 03760 and

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September 2017

A Comparative Study of Phenolic Antioxidant Activity and Flavonoid Biosynthesis-Related Gene Expression Between Summer and Winter Strawberry Cultivars.

J Food Sci 2017 Feb 18;82(2):341-349. Epub 2017 Jan 18.

Dept. of Plant Science, Gangneung-Wonju Natl. Univ., 7 Jukheon-Gil, Gangneung, 25457, Republic of Korea.

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February 2017

A novel synthetic cathinone, 2-(methylamino)-1-(naphthalen-2-yl) propan-1-one (BMAPN), produced rewarding effects and altered striatal dopamine-related gene expression in mice.

Behav Brain Res 2017 01 11;317:494-501. Epub 2016 Oct 11.

Uimyung Research Institute for Neuroscience, School of Pharmacy, Sahmyook University, 815 Hwarangro, Nowon-gu, Seoul, 01795, Republic of Korea. Electronic address:

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January 2017

PKCδ knockout mice are protected from para-methoxymethamphetamine-induced mitochondrial stress and associated neurotoxicity in the striatum of mice.

Neurochem Int 2016 11 10;100:146-158. Epub 2016 Sep 10.

Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea. Electronic address:

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November 2016

The expression of methiopropamine-induced locomotor sensitization requires dopamine D2, but not D1, receptor activation in the rat.

Behav Brain Res 2016 09 3;311:403-407. Epub 2016 Jun 3.

Department of Physiology, Brain Korea 21 Plus Project for Medical Science, Brain Research Institute, Yonsei University College of Medicine, Seoul 120-752, South Korea. Electronic address:

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September 2016

Synthesis of novel flavone derivatives possessing substituted benzamides and their biological evaluation against human cancer cells.

Bioorg Med Chem Lett 2016 09 28;26(17):4170-3. Epub 2016 Jul 28.

Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, 26 Kyungheedae-ro, Seoul 02447, Republic of Korea; Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Seoul 02447, Republic of Korea. Electronic address:

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September 2016

Synthesis and biological evaluation of 1,2-dithiol-3-thiones and pyrrolo[1,2-a]pyrazines as novel hypoxia inducible factor-1 (HIF-1) inhibitor.

Bioorg Med Chem 2016 06 26;24(12):2843-51. Epub 2016 Apr 26.

Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul 02447, Republic of Korea; Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea. Electronic address:

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June 2016

Galangin and kaempferol suppress phorbol-12-myristate-13-acetate-induced matrix metalloproteinase-9 expression in human fibrosarcoma HT-1080 cells.

Mol Cells 2015 10;38(2):151-5. Epub 2014 Dec 10.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.

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November 2015

Synthesis of (2-amino)ethyl derivatives of quercetin 3-O-methyl ether and their antioxidant and neuroprotective effects.

Bioorg Med Chem 2015 Aug 21;23(15):4970-9. Epub 2015 May 21.

Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, Seoul 130-701, Republic of Korea; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea. Electronic address:

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August 2015

Synthesis of aminoalkyl-substituted aurone derivatives as acetylcholinesterase inhibitors.

Bioorg Med Chem 2015 Jan 13;23(1):231-40. Epub 2014 Nov 13.

Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, 26 Kyungheedae-ro, Seoul 130-701, Republic of Korea; Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Seoul 130-701, Republic of Korea. Electronic address:

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January 2015

Synthesis of aminoalkyl-substituted coumarin derivatives as acetylcholinesterase inhibitors.

Bioorg Med Chem 2014 Feb 11;22(4):1262-7. Epub 2014 Jan 11.

Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea; Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, Republic of Korea. Electronic address:

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February 2014

Construction and characterization of functional anti-epiregulin humanized monoclonal antibodies.

Biochem Biophys Res Commun 2013 Nov 12;441(4):1011-7. Epub 2013 Nov 12.

Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan.

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November 2013

The presence of outer arm fucose residues on the N-glycans of tissue inhibitor of metalloproteinases-1 reduces its activity.

J Proteome Res 2013 Aug 1;12(8):3547-60. Epub 2013 Jul 1.

Department of Biochemistry, College of Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

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August 2013

Synthesis of indolyl-3-acetonitrile derivatives and their inhibitory effects on nitric oxide and PGE2 productions in LPS-induced RAW 264.7 cells.

Bioorg Med Chem Lett 2013 May 7;23(9):2571-4. Epub 2013 Mar 7.

Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea.

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May 2013

Significant enhancement of the power conversion efficiency for organic photovoltaic cells due to a P3HT pillar layer containing ZnSe quantum dots.

Opt Express 2012 May;20(10):10476-83

Department of Electronics and Computer Engineering, Hanyang University, Seoul 133-791, Korea.

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May 2012

Hypoxia-inducible factor-1α inhibition by a pyrrolopyrazine metabolite of oltipraz as a consequence of microRNAs 199a-5p and 20a induction.

Carcinogenesis 2012 Mar 4;33(3):661-9. Epub 2012 Jan 4.

Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul 151-742, South Korea.

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March 2012

Differentiation between benign and malignant solid thyroid nodules using an US classification system.

Korean J Radiol 2011 Sep-Oct;12(5):559-67. Epub 2011 Aug 24.

Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan 614-725, Korea.

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January 2012

4'-bromo-5,6,7-trimethoxyflavone represses lipopolysaccharide-induced iNOS and COX-2 expressions by suppressing the NF-κB signaling pathway in RAW 264.7 macrophages.

Bioorg Med Chem Lett 2012 Jan 31;22(1):700-5. Epub 2011 Oct 31.

Department of Life and Nanopharmaceutical Science & Department of Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul 130 701, Republic of Korea.

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January 2012

Wide-angle catadioptric lens with a rectilinear projection scheme.

Appl Opt 2006 Dec;45(34):8659-73

Department of Optoelectronics, Honam University, Gwangju, South Korea.

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December 2006