Publications



A novel synthetic cathinone, 2-(methylamino)-1-(naphthalen-2-yl) propan-1-one (BMAPN), produced rewarding effects and altered striatal dopamine-related gene expression in mice.
Behav Brain Res 2017 Jan 11;317:494-501. Epub 2016 Oct 11.
Uimyung Research Institute for Neuroscience, School of Pharmacy, Sahmyook University, 815 Hwarangro, Nowon-gu, Seoul, 01795, Republic of Korea. Electronic address:

PKCδ knockout mice are protected from para-methoxymethamphetamine-induced mitochondrial stress and associated neurotoxicity in the striatum of mice.
Neurochem Int 2016 Nov 10;100:146-158. Epub 2016 Sep 10.
Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea. Electronic address:


Synthesis of (2-amino)ethyl derivatives of quercetin 3-O-methyl ether and their antioxidant and neuroprotective effects.
Bioorg Med Chem 2015 Aug 21;23(15):4970-9. Epub 2015 May 21.
Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, Seoul 130-701, Republic of Korea; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea. Electronic address:

Synthesis of aminoalkyl-substituted aurone derivatives as acetylcholinesterase inhibitors.
Bioorg Med Chem 2015 Jan 13;23(1):231-40. Epub 2014 Nov 13.
Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, 26 Kyungheedae-ro, Seoul 130-701, Republic of Korea; Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Seoul 130-701, Republic of Korea. Electronic address:

Synthesis of aminoalkyl-substituted coumarin derivatives as acetylcholinesterase inhibitors.
Bioorg Med Chem 2014 Feb 11;22(4):1262-7. Epub 2014 Jan 11.
Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea; Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, Republic of Korea. Electronic address:

Construction and characterization of functional anti-epiregulin humanized monoclonal antibodies.
Biochem Biophys Res Commun 2013 Nov 12;441(4):1011-7. Epub 2013 Nov 12.
Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan.

The presence of outer arm fucose residues on the N-glycans of tissue inhibitor of metalloproteinases-1 reduces its activity.
J Proteome Res 2013 Aug 1;12(8):3547-60. Epub 2013 Jul 1.
Department of Biochemistry, College of Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

4'-bromo-5,6,7-trimethoxyflavone represses lipopolysaccharide-induced iNOS and COX-2 expressions by suppressing the NF-κB signaling pathway in RAW 264.7 macrophages.
Bioorg Med Chem Lett 2012 Jan 31;22(1):700-5. Epub 2011 Oct 31.
Department of Life and Nanopharmaceutical Science & Department of Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul 130 701, Republic of Korea.

Synthesis and biological evaluation of 1,2-dithiol-3-thiones and pyrrolo[1,2-a]pyrazines as novel hypoxia inducible factor-1 (HIF-1) inhibitor.
Bioorg Med Chem 2016 06 26;24(12):2843-51. Epub 2016 Apr 26.
Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul 02447, Republic of Korea; Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea. Electronic address:

Synthesis of novel flavone derivatives possessing substituted benzamides and their biological evaluation against human cancer cells.
Bioorg Med Chem Lett 2016 09 28;26(17):4170-3. Epub 2016 Jul 28.
Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, 26 Kyungheedae-ro, Seoul 02447, Republic of Korea; Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Seoul 02447, Republic of Korea. Electronic address:

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