Publications by authors named "Young-Guen Kwon"

100Publications

Human plasminogen-derived N-acetyl-Arg-Leu-Tyr-Glu antagonizes VEGFR-2 to prevent blood-retinal barrier breakdown in diabetic mice.

Biomed Pharmacother 2020 Dec 15;134:111110. Epub 2020 Dec 15.

Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do, 24341, Republic of Korea; Kangwon Institute of Inclusive Technology, Kangwon National University, Chuncheon, Gangwon-Do, 24341, Republic of Korea. Electronic address:

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December 2020

The endothelial dysfunction blocker CU06-1004 ameliorates choline-deficient L-amino acid diet-induced non-alcoholic steatohepatitis in mice.

PLoS One 2020 4;15(12):e0243497. Epub 2020 Dec 4.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.

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December 2020

CU06-1004 Alleviates Experimental Colitis by Modulating Colonic Vessel Dysfunction.

Front Pharmacol 2020 15;11:571266. Epub 2020 Sep 15.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.

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September 2020

Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia.

Cells 2020 08 31;9(9). Epub 2020 Aug 31.

Departments of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do 24341, Korea.

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August 2020

NF-κB-dependent miR-31/155 biogenesis is essential for TNF-α-induced impairment of endothelial progenitor cell function.

Exp Mol Med 2020 08 7;52(8):1298-1309. Epub 2020 Aug 7.

Department of Molecular and Cellular Biochemistry, Kangwon National University School of Medicine, Chuncheon, Gangwon-do, 24341, South Korea.

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August 2020

CU06-1004 (endothelial dysfunction blocker) ameliorates astrocyte end-feet swelling by stabilizing endothelial cell junctions in cerebral ischemia/reperfusion injury.

J Mol Med (Berl) 2020 06 16;98(6):875-886. Epub 2020 May 16.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

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June 2020

CLEC14A deficiency exacerbates neuronal loss by increasing blood-brain barrier permeability and inflammation.

J Neuroinflammation 2020 Feb 4;17(1):48. Epub 2020 Feb 4.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, South Korea.

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February 2020

MicroRNA-148a/b-3p regulates angiogenesis by targeting neuropilin-1 in endothelial cells.

Exp Mol Med 2019 11 13;51(11):1-11. Epub 2019 Nov 13.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Korea.

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November 2019

N-Terminal Modification of the Tetrapeptide Arg-Leu-Tyr-Glu, a Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) Antagonist, Improves Antitumor Activity by Increasing its Stability against Serum Peptidases.

Mol Pharmacol 2019 12 8;96(6):692-701. Epub 2019 Oct 8.

Departments of Molecular and Cellular Biochemistry (J.-A.Y., J.K., Y.-Y.B., W.P., M.P., S.K., T.K., S.C., K.-S.H., Y.-M.K.) and Neurobiology, School of Medicine (M.-H.W.), Departments of Biochemistry, College of Natural Sciences (D.J.) and Life Sciences, College of Natural Sciences (H.L.), and Kangwon Institute of Inclusive Technology (J.K., Y.-M.K.), Kangwon National University, Chuncheon, Gangwon-do, and Department of Anesthesiology and Pain Medicine, Hanyang University Hospital, Seoul (J.-Y.K.), and Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul (Y.-G.K.), Korea

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December 2019

Stabilization of Intrinsically Disordered DKK2 Protein by Fusion to RNA-Binding Domain.

Int J Mol Sci 2019 Jun 11;20(11). Epub 2019 Jun 11.

Department of Biotechnology, College of Life Sciences and Biotechnology, Yonsei University, Seoul 03722, Korea.

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June 2019

SALM4 regulates angiogenic functions in endothelial cells through VEGFR2 phosphorylation at Tyr1175.

FASEB J 2019 09 6;33(9):9842-9857. Epub 2019 Jun 6.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.

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September 2019

NF-κB-responsive miR-155 induces functional impairment of vascular smooth muscle cells by downregulating soluble guanylyl cyclase.

Exp Mol Med 2019 02 15;51(2):1-12. Epub 2019 Feb 15.

Departments of Molecular and Cellular Biochemistry, Kangwon National University School of Medicine, Chuncheon, Gangwon-do, 24341, South Korea.

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February 2019

Heme oxygenase metabolites improve astrocytic mitochondrial function via a Ca2+-dependent HIF-1α/ERRα circuit.

PLoS One 2018 28;13(8):e0202039. Epub 2018 Aug 28.

Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Kangwon-do, Republic of Korea.

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February 2019

Pericyte-Derived Dickkopf2 Regenerates Damaged Penile Neurovasculature Through an Angiopoietin-1-Tie2 Pathway.

Diabetes 2018 06 20;67(6):1149-1161. Epub 2018 Mar 20.

National Research Center for Sexual Medicine and Department of Urology, Inha University School of Medicine, Incheon, Republic of Korea

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June 2018

REDD-1 aggravates endotoxin-induced inflammation via atypical NF-κB activation.

FASEB J 2018 08 16;32(8):4585-4599. Epub 2018 Mar 16.

Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, South Korea.

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August 2018

Hippo-YAP/TAZ signaling in angiogenesis.

BMB Rep 2018 Mar;51(3):157-162

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University; Initiative for Biological Function & Systems, BK21 PLUS, Yonsei University, Seoul 03722, Korea.

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March 2018

Dickkopf2 rescues erectile function by enhancing penile neurovascular regeneration in a mouse model of cavernous nerve injury.

Sci Rep 2017 12 19;7(1):17819. Epub 2017 Dec 19.

National Research Center for Sexual Medicine and Department of Urology, Inha University School of Medicine, Incheon, 22332, Republic of Korea.

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December 2017

Carbon monoxide prevents TNF-α-induced eNOS downregulation by inhibiting NF-κB-responsive miR-155-5p biogenesis.

Exp Mol Med 2017 11 24;49(11):e403. Epub 2017 Nov 24.

Departments of Molecular and Cellular Biochemistry, Kangwon National University School of Medicine, Chuncheon, Gangwon-do, South Korea.

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November 2017

LDB2 regulates the expression of DLL4 through the formation of oligomeric complexes in endothelial cells.

BMB Rep 2018 Jan;51(1):21-26

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.

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January 2018

The caspase-8/Bid/cytochrome c axis links signals from death receptors to mitochondrial reactive oxygen species production.

Free Radic Biol Med 2017 11 6;112:567-577. Epub 2017 Sep 6.

Departments of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do, South Korea. Electronic address:

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November 2017

Integrative analysis of DNA methylation and mRNA expression during differentiation of umbilical cord blood derived mononuclear cells to endothelial cells.

Gene 2017 Nov 6;635:48-60. Epub 2017 Sep 6.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea. Electronic address:

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November 2017

YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation.

J Clin Invest 2017 Sep 14;127(9):3441-3461. Epub 2017 Aug 14.

Center for Vascular Research, Institute for Basic Science, Daejeon, South Korea.

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September 2017

A miRNA-101-3p/Bim axis as a determinant of serum deprivation-induced endothelial cell apoptosis.

Cell Death Dis 2017 05 18;8(5):e2808. Epub 2017 May 18.

Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do 24341, Republic of Korea.

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May 2017

Hhip regulates tumor-stroma-mediated upregulation of tumor angiogenesis.

Exp Mol Med 2017 01 27;49(1):e289. Epub 2017 Jan 27.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.

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January 2017

Carbon monoxide stimulates astrocytic mitochondrial biogenesis via L-type Ca channel-mediated PGC-1α/ERRα activation.

Biochem Biophys Res Commun 2016 Oct 14;479(2):297-304. Epub 2016 Sep 14.

Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Kangwon-do 200-701, Republic of Korea. Electronic address:

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October 2016

The endothelial E3 ligase HECW2 promotes endothelial cell junctions by increasing AMOTL1 protein stability via K63-linked ubiquitination.

Cell Signal 2016 11 4;28(11):1642-51. Epub 2016 Aug 4.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea. Electronic address:

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November 2016

A small molecule inhibitor for ATPase activity of Hsp70 and Hsc70 enhances the immune response to protein antigens.

Sci Rep 2015 Dec 3;5:17642. Epub 2015 Dec 3.

National Creative Research Initiative Center for Biofunctional Molecules, Department of Chemistry, Yonsei University, Seoul 03722, Korea.

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December 2015

Lipopolysaccharide induction of REDD1 is mediated by two distinct CREB-dependent mechanisms in macrophages.

FEBS Lett 2015 Sep 18;589(19 Pt B):2859-65. Epub 2015 Aug 18.

Departments of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do 200-701, South Korea. Electronic address:

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September 2015

Loss of NDRG2 promotes epithelial-mesenchymal transition of gallbladder carcinoma cells through MMP-19-mediated Slug expression.

J Hepatol 2015 Dec 17;63(6):1429-39. Epub 2015 Aug 17.

Functional Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea; Department of Biomolecular Science, University of Science & Technology, Daejeon, Republic of Korea. Electronic address:

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December 2015

BMP9 Induces Cord Blood-Derived Endothelial Progenitor Cell Differentiation and Ischemic Neovascularization via ALK1.

Arterioscler Thromb Vasc Biol 2015 Sep 30;35(9):2020-31. Epub 2015 Jul 30.

From the Department of Biochemistry, College of Life Science and Biotechnology (J.K., Y.J., W.-b.L., H.P., Y.-G.K.) and Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, College of Medicine (J.-Y.K.), Yonsei University, Seoul, Korea; School of Interdisciplinary Biosciences and Bioengineering, Pohang University of Science and Technology, Pohang, Korea (M.K., D.H.); Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Korea (M.K.); and Department of new Biology, Daegu Gyeongbuk Institute of Science and Technology, Daegu, Korea (D.H.).

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September 2015

Roles of YAP in mediating endothelial cell junctional stability and vascular remodeling.

BMB Rep 2015 Aug;48(8):429-30

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.

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August 2015

Endothelial Snail Regulates Capillary Branching Morphogenesis via Vascular Endothelial Growth Factor Receptor 3 Expression.

PLoS Genet 2015 Jul 6;11(7):e1005324. Epub 2015 Jul 6.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.

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July 2015

The tetrapeptide Arg-Leu-Tyr-Glu inhibits VEGF-induced angiogenesis.

Biochem Biophys Res Commun 2015 Aug 4;463(4):532-7. Epub 2015 Jun 4.

Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do, 200-702, South Korea. Electronic address:

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August 2015

Yes-associated protein regulates endothelial cell contact-mediated expression of angiopoietin-2.

Nat Commun 2015 May 12;6:6943. Epub 2015 May 12.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

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May 2015

p-Hydroxybenzyl alcohol-containing biodegradable nanoparticle improves functional blood flow through angiogenesis in a mouse model of hindlimb ischemia.

Biomaterials 2015 24;53:679-87. Epub 2015 Mar 24.

Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do 200-701, South Korea. Electronic address:

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January 2016

Stimulation of angiogenesis and survival of endothelial cells by human monoclonal Tie2 receptor antibody.

Biomaterials 2015 May 17;51:119-128. Epub 2015 Feb 17.

Functional Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea; Department of Biomolecular Science, University of Science & Technology, Daejeon, Republic of Korea. Electronic address:

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May 2015

Heterochromatin Protein 1 Alpha (HP1α: CBX5) is a Key Regulator in Differentiation of Endothelial Progenitor Cells to Endothelial Cells.

Stem Cells 2015 May;33(5):1512-22

Corneal Dystrophy Research Institute; Department of Ophthalmology, Yonsei University College of Medicine, Seoul, 120-752, Korea; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 120-749, Korea.

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May 2015

Effects of high-fat diet on neuronal damage, gliosis, inflammatory process and oxidative stress in the hippocampus induced by transient cerebral ischemia.

Neurochem Res 2014 Dec 12;39(12):2465-78. Epub 2014 Oct 12.

Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou, 225001, China.

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December 2014

Combined effect of vascular-leakage-blocker Sac-1004 and antiangiogenic drug sunitinib on tumor angiogenesis.

Biochem Biophys Res Commun 2014 Aug 5;450(4):1320-6. Epub 2014 Jul 5.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, 262 Seongsanno, Seodaemun-Gu, Seoul 120-749, Republic of Korea. Electronic address:

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August 2014

Multiple paracrine factors secreted by mesenchymal stem cells contribute to angiogenesis.

Vascul Pharmacol 2014 Oct 2;63(1):19-28. Epub 2014 Jul 2.

Departments of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do 200-701, Republic of Korea. Electronic address:

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October 2014

Functional role of NF-κB in expression of human endothelial nitric oxide synthase.

Biochem Biophys Res Commun 2014 May 21;448(1):101-7. Epub 2014 Apr 21.

Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do 200-702, South Korea. Electronic address:

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May 2014

Glucal-conjugated sterols as novel vascular leakage blocker: structure-activity relationship focusing on the C17-side chain.

Eur J Med Chem 2014 Mar 25;75:184-94. Epub 2014 Jan 25.

College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 151-742, Republic of Korea. Electronic address:

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March 2014

Korean Red Ginseng protects endothelial cells from serum-deprived apoptosis by regulating Bcl-2 family protein dynamics and caspase S-nitrosylation.

J Ginseng Res 2013 Oct;37(4):413-24

Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon 200-701, Korea.

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October 2013

TRAIL negatively regulates VEGF-induced angiogenesis via caspase-8-mediated enzymatic and non-enzymatic functions.

Angiogenesis 2014 Jan 5;17(1):179-94. Epub 2013 Oct 5.

Vascular Homeostasis Laboratory and Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do, 200-701, Korea.

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January 2014

Distinct roles of DKK1 and DKK2 in tumor angiogenesis.

Angiogenesis 2014 Jan 4;17(1):221-34. Epub 2013 Oct 4.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 120-752, Republic of Korea.

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January 2014

The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc/Vegfr3 signaling in zebrafish.

Development 2013 Oct;140(19):4081-90

Department of Cell Biology, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.

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October 2013

Rk1, a ginsenoside, is a new blocker of vascular leakage acting through actin structure remodeling.

PLoS One 2013 22;8(7):e68659. Epub 2013 Jul 22.

Department of Biochemistry College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.

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February 2014

Sac-1004, a novel vascular leakage blocker, enhances endothelial barrier through the cAMP/Rac/cortactin pathway.

Biochem Biophys Res Commun 2013 Jun 9;435(3):420-7. Epub 2013 May 9.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

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June 2013

Recruitment of monocytes/macrophages in different tumor microenvironments.

Biochim Biophys Acta 2013 Apr 31;1835(2):170-9. Epub 2012 Dec 31.

Department of Biochemistry, Yonsei University, Seoul, Republic of Korea.

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April 2013

Ginseng Berry Extract Prevents Atherogenesis via Anti-Inflammatory Action by Upregulating Phase II Gene Expression.

Evid Based Complement Alternat Med 2012 25;2012:490301. Epub 2012 Nov 25.

Vascular Homeostasis Laboratory and Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Gangwon-do, Chuncheon 200-701, Republic of Korea.

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December 2012

Kurarinone promotes TRAIL-induced apoptosis by inhibiting NF-κB-dependent cFLIP expression in HeLa cells.

Exp Mol Med 2012 Nov;44(11):653-64

Vascular Homeostasis Laboratory, Departments of Molecular and Cellular Biochemistry and Institute of Medical Sciences School of Medicine Kangwon National University.

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November 2012

Regulation of ROS production and vascular function by carbon monoxide.

Oxid Med Cell Longev 2012 9;2012:794237. Epub 2012 Aug 9.

Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do 200-701, Republic of Korea.

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November 2012

The Wnt pathway and the roles for its antagonists, DKKS, in angiogenesis.

IUBMB Life 2012 Sep 18;64(9):724-31. Epub 2012 Jul 18.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.

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September 2012

Nuclear IL-33 is a transcriptional regulator of NF-κB p65 and induces endothelial cell activation.

Biochem Biophys Res Commun 2012 May 7;421(2):305-11. Epub 2012 Apr 7.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

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May 2012

Functional dissection of Nrf2-dependent phase II genes in vascular inflammation and endotoxic injury using Keap1 siRNA.

Free Radic Biol Med 2012 Aug 27;53(3):629-40. Epub 2012 Apr 27.

Vascular Homeostasis Laboratory and Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chunchon, Kangwon-do, Korea.

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August 2012

A novel sLRP6E1E2 inhibits canonical Wnt signaling, epithelial-to-mesenchymal transition, and induces mitochondria-dependent apoptosis in lung cancer.

PLoS One 2012 14;7(5):e36520. Epub 2012 May 14.

Brain Korea 21 Project for Medical Sciences, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.

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October 2012

Senescence of fetal endothelial progenitor cell in pregnancy with idiopathic fetal growth restriction.

J Matern Fetal Neonatal Med 2012 Sep 13;25(9):1769-73. Epub 2012 Mar 13.

Department of Obstetrics and Gynecology, Konkuk University School of Medicine, Seoul, Korea.

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September 2012

Extracellular taurine induces angiogenesis by activating ERK-, Akt-, and FAK-dependent signal pathways.

Eur J Pharmacol 2012 Jan 23;674(2-3):188-99. Epub 2011 Nov 23.

Vascular System Research Center, School of Medicine, Kangwon National University, South Korea.

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January 2012

Chk1 and Hsp90 cooperatively regulate phosphorylation of endothelial nitric oxide synthase at serine 1179.

Free Radic Biol Med 2011 Dec 25;51(12):2217-26. Epub 2011 Sep 25.

Department of Molecular Medicine and Ewha Medical Research Institute, Ewha Womans University Medical School, Seoul 158-710, Korea.

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December 2011

Homeobox D1 regulates angiogenic functions of endothelial cells via integrin β1 expression.

Biochem Biophys Res Commun 2011 Apr 9;408(1):186-92. Epub 2011 Apr 9.

College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.

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April 2011

Pre- and post-treatments with escitalopram protect against experimental ischemic neuronal damage via regulation of BDNF expression and oxidative stress.

Exp Neurol 2011 Jun 31;229(2):450-9. Epub 2011 Mar 31.

Laboratory of Veterinary Pharmacology, College of Veterinary Medicine, Seoul National University, Seoul 151-742, South Korea.

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June 2011

The cell adhesion molecule L1 promotes gallbladder carcinoma progression in vitro and in vivo.

Oncol Rep 2011 Apr 11;25(4):945-52. Epub 2011 Feb 11.

Therapeutic Antibody Research Center, Korea Research Institute of Bioscience and Biotechnology, 52 Eoeun-dong, Yuseong-gu, Daejeon 305-333, Republic of Korea.

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April 2011

Sac-0601 prevents retinal vascular leakage in a mouse model of diabetic retinopathy.

Eur J Pharmacol 2011 Apr 4;657(1-3):35-40. Epub 2011 Feb 4.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120–749, Republic of Korea.

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April 2011

Antioxidant enzymes are differently changed in experimental ischemic hippocampal CA1 region following repeated restraint stress.

J Neurol Sci 2011 Mar 6;302(1-2):33-42. Epub 2011 Jan 6.

Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 200-701, Republic of Korea.

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March 2011

Clec14a is specifically expressed in endothelial cells and mediates cell to cell adhesion.

Biochem Biophys Res Commun 2011 Jan 21;404(1):103-8. Epub 2010 Nov 21.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.

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January 2011

Cholesterol-derived novel anti-apoptotic agents on the structural basis of ginsenoside Rk1.

Bioorg Med Chem Lett 2010 Dec 21;20(23):7102-5. Epub 2010 Oct 21.

College of Pharmacy, Seoul National University, Gwanak-gu, Seoul, Republic of Korea.

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December 2010

Mel-18, a mammalian Polycomb gene, regulates angiogenic gene expression of endothelial cells.

Biochem Biophys Res Commun 2010 Oct 27;400(4):523-30. Epub 2010 Aug 27.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.

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October 2010